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1. Abstracts of the 33rd International Austrian Winter Symposium

Author

K. Binzel, A. Adelaja, C. L. Wright, D. Scharre, J. Zhang, M. V. Knopp, E. J. Teoh, D. Bottomley, A. Scarsbrook, H. Payne, A. Afaq, J. Bomanji, N. van As, S. Chua, P. Hoskin, A. Chambers, G. J. Cook, V. S. Warbey, A. Chau, P. Ward, M. P. Miller, D. J. Stevens, L. Wilson, F. V. Gleeson, K. Scheidhauer, C. Seidl, M. Autenrieth, F. Bruchertseifer, C. Apostolidis, F. Kurtz, T. Horn, C. Pfob, M. Schwaiger, J. Gschwend, C. D’Alessandria, A. Morgenstern, C. Uprimny, A. Kroiss, C. Decristoforo, E. von Guggenberg, B. Nilica, W. Horninger, I. Virgolini, S. Rasul, N. Poetsch, A. Woehrer, M. Preusser, M. Mitterhauser, W. Wadsak, G. Widhalm, M. Mischkulnig, M. Hacker, T. Traub-Weidinger, E. J. Wuthrick, E. D. Miller, P. Maniawski, Sebastijan Rep, Marko Hocevar, Janja Vaupotic, Urban Zdesar, Katja Zaletel, Luka Lezaic, S. Mairinger, Thomas Filip, M. Sauberer, S. Flunkert, T. Wanek, J. Stanek, N. Okamura, O. Langer, C. Kuntner, M. C. Fornito, R. Balzano, V. Di Martino, S. Cacciaguerra, G. Russo, D. Seifert, M. Kleinova, A. Cepa, J. Ralis, P. Hanc, O. Lebeda, M. Mosa, S. Vandenberghe, E. Mikhaylova, D. Borys, V. Viswanath, M. Stockhoff, N. Efthimiou, P. Caribe, R. Van Holen, J. S. Karp, P. M. Haller, C. Farhan, E. Piackova, B. Jäger, P. Knoll, A. Kiss, B. K. Podesser, J. Wojta, K. Huber, S. Mirzaei, A. Traxl, K. Komposch, Elisabeth Glitzner, M. Sibilia, M. Russello, S. Sorko, H. J. Gallowitsch, S. Kohlfuerst, S. Matschnig, M. Rieser, M. Sorschag, P. Lind, L. Ležaič, S. Rep, J. Žibert, N. Frelih, S. Šuštar, R. P. Baum, T. Langbein, A. Singh, M. Shahinfar, C. Schuchardt, G. F. Volk, H. R. Kulkarni, G. V. Di Martino, W. H. Thomson, M. Kudlacek, M. Karik, H. Rieger, W. Pokieser, K. Glaser, V. Petz, C. Tugendsam, W. Buchinger, B. Schmoll-Hauer, I. P. Schenk, K. Rudolph, M. Krebs, G. Zettinig, V. Zoufal, M. Krohn, T. Filip, J. Pahnke, F. Weitzer, B. Pernthaler, S. Salamon, R. Aigner, P. Koranda, L. Henzlová, M. Kamínek, Mo. Váchalová, P. Bachleda, D. Summer, J. Garousi, M. Oroujeni, B. Mitran, K. G. Andersson, A. Vorobyeva, J.n Löfblom, A. Orlova, V. Tolmachev, P. Kaeopookum, T. Orasch, B. Lechner, M. Petrik, Z. Novy, C. Rangger, and H. Haas

Subjects
Siderophore, Biochemistry, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Bifunctional chelator, business, Egfr expression, Conjugate
Abstract

Aim: Zirconium-89 has gained great interest for PET, when imaging at late time points is required. Desferrioxamine B (DFO), is mostly used for this radionuclide as bifunctional chelator (BFC) and w ...

Published
2018
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2. Malignant Pleural and Pericardial Effusion in Invasive Breast Cancer: Impact of the Site of the Primary Tumor

Author

M. Vesely, W. Ulrich, P. Cassik, W. Pokieser, Peters-Engl C, and G. Fischer

Subjects
Cancer Research, medicine.medical_specialty, Breast Neoplasms, Pericardial effusion, Medical Records, Pericardial Effusion, Metastasis, Pleural disease, Breast cancer, Humans, Medicine, Neoplasm Invasiveness, Survival rate, Neoplasm Staging, Retrospective Studies, business.industry, Respiratory disease, Pericardial fluid, Middle Aged, medicine.disease, Primary tumor, Pleural Effusion, Malignant, Surgery, Oncology, Austria, Case-Control Studies, Female, Radiology, business
Abstract

Background. Malignant effusion in invasive breast cancer, either pleural or pericardial, is associated with a poor survival rate. We investigated the role of the location of invasive breast cancer in developing malignant pleural or pericardial effusion. Methods. Three thousand eight hundred and fifty six women with a history of invasive breast cancer between 1960 and 1994 were analyzed in a retrospective study. Two hundred and six patients (5.34%; group A) developed malignant pleural and/or pericardial fluid as the first visible clinical sign of distant metastasis. A control group of 206 patients (group B) without malignant effusions were matched in terms of clinical and pathological characteristics. The two groups were compared in respect of the location of the primary tumor. Fifty patients in group A (n = 50; 24.2%) had tumors in the inner quadrants, 83 patients (n = 83; 40.3%) in the outer quadrants, and 13 patients (n = 13; 6.3%) in a central location. No data were available for 60 patients (n = 60; 29.1%). In group B, 12 patients (n = 12; 5.9%) had tumors in the inner quadrants, 140 patients (n = 140; 68.0%) in the outer quadrants, 14 patients (n = 14; 6.8%) had centrally located tumors, while no data were available for 40 patients (n = 40; 19.4%). Invasive ductal carcinomas (IDC) located in the inner quadrants were highly significantly associated with increased pleural or pericardial effusion as the first site of distant metastasis (p ≤ 0.0001; chi-square tests). Conclusion. IDC in the inner quadrants were associated with a 4-fold higher rate of malignant pleural or pericardial effusions. Further studies will have to determine whether tumor location is a criterion for more aggressive adjuvant therapy.

Published
2004
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