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34 results on '"Venturini, E"'

4. Genomic characterization of asymptomatic CT-detected lung cancers

Author

Belloni, E, primary, Veronesi, G, additional, Micucci, C, additional, Javan, S, additional, Minardi, S P, additional, Venturini, E, additional, Maisonneuve, P, additional, Volorio, S, additional, Riboni, M, additional, Bellomi, M, additional, Scanagatta, P, additional, Taliento, G, additional, Pelosi, G, additional, Pece, S, additional, Spaggiari, L, additional, and Pelicci, P G, additional

Published
2010
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20. Novel Processing of Hts Based Conductors

Author

Ginley, D. S., primary, Venturini, E. L., additional, Kwak, J. F., additional, Baughman, R. J., additional, Bourceer, R. J., additional, Mitchell, M. A., additional, Morosin, B., additional, Halloran, J. W., additional, Neal, M. J., additional, and Ca- Pone, D. W., additional

Published
1989
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26. Bulk Superconductivity in La2CuO4

Author

Schirber, J. E., primary, Venturini, E. L., additional, Morosin, B., additional, Kwak, J. F., additional, Ginley, D. S., additional, and Baughman, R. J., additional

Published
1987
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32. Treatment of children with COVID-19: update of the Italian Society of Pediatric Infectious Diseases position paper

Author

Elisabetta Venturini, Carlotta Montagnani, Silvia Garazzino, Daniele Donà, Luca Pierantoni, Andrea Lo Vecchio, Andrzej Krzysztofiak, Giangiacomo Nicolini, Sonia Bianchini, Luisa Galli, Alberto Villani, Guido Castelli Gattinara, the Italian SITIP-SIP SARS-Cov-2 pediatric infection study group, Venturini, E., Montagnani, C., Garazzino, S., Dona, D., Pierantoni, L., Lo Vecchio, A., Krzysztofiak, A., Nicolini, G., Bianchini, S., Galli, L., Villani, A., and Gattinara, G. C.

Subjects
Male, 2019-20 coronavirus outbreak, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MEDLINE, Pediatrics, RJ1-570, Medical, medicine, Humans, Disease management (health), Child, Intensive care medicine, Letter to the Editor, book, Societies, Medical, Infectious Disease Medicine, SARS-CoV-2, business.industry, COVID-19, Disease Management, Settore MED/38, Italy, Practice Guidelines as Topic, Pediatric Infectious Disease, Position paper, book.journal, Female, Periodicals as Topic, Societies, business, Human
Published
2021
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33. Is kinesiophobia a predictor of early functional performance after total hip replacement? A prospective prognostic cohort study

Author

A. Ruggiero, A Culcasi, Mattia Morri, C Govoni, E. Venturini, Riccardo Ruisi, Natalia Franchini, Maria Grazia Benedetti, Morri M., Venturini E., Franchini N., Ruisi R., Culcasi A., Ruggiero A., Govoni C., and Benedetti M.G.

Subjects
medicine.medical_specialty, lcsh:Diseases of the musculoskeletal system, WOMAC, Sports medicine, Arthroplasty, Replacement, Hip, medicine.medical_treatment, Population, Osteoarthritis, Hip, Hip replacement (animal), Arthroplasty, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Osteoarthritis, medicine, Humans, Psychology, Orthopedics and Sports Medicine, Prospective Studies, 030212 general & internal medicine, Functional ability, education, Ontario, education.field_of_study, business.industry, Recovery of function, Osteoarthritis, Knee, Physical Functional Performance, Prognosis, Treatment Outcome, Physical therapy, Osteoarthriti, Female, lcsh:RC925-935, business, Body mass index, 030217 neurology & neurosurgery, Research Article, Cohort study
Abstract

Background Considerable attention has been paid to the role of kinesiophobia with respect to knee prosthesis but it has not yet been studied as a prognostic factor of short-term functional performance following total hip replacement. The main purpose of the present study is to examine the possible predictors of early functional performance of patients undergoing total primary hip arthroplasty, including demographics as age, sex and body mass index, preoperative functional ability, type of anaesthesia, level of haemoglobin, pain and level of kinesiophobia before surgery. Secondly, we want to describe the main characteristics of the population with the highest levels of kinesiophobia. Methods A prospective, prognostic cohort study was carried out. Patients undergoing primary hip replacement were recruited consecutively. The main outcome is the early functional performance achieved by patients after surgery and measured using the Iowa Level of Assistance (ILOA) scale on the fifth postoperative day. Preoperative kinesiophobia was measured by the Tampa Scale and the preoperative functional ability by the Western Ontario and McMaster Osteoarthritis Index (WOMAC). The multivariate analysis was performed by the General Linear Model. The analysis of the population with high levels of kinesiophobia was conducted by identifying a cut-off of 40 compared to the Tampa Scale. Results Statistical analysis was performed on 269 patients. The average ILOA score recorded was 19.5 (DS 8.3). The levels of kinesiophobia, showed an average score of 35.1 (7.8) and it was not associated with early functional performance. The independent predictive factors include age, sex and body mass index. Kinesiophobia high levels were recorded in 30% of the population and this population had a higher level of pre-operative WOMAC score. Conclusions Early functional performance after hip replacement surgery was not correlated with the level of kinesiophobia. Three significant factors that describe a population most at risk of not achieving optimal functional performance are increased age, being female and increase in body mass index. In the preoperative phase, high levels of kinesiophobia were associated with more impaired preoperative functional ability. Trial registration Current Controlled Trials NCT02786121, May 2016. Retrospectively registered.

Published
2020
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34. Genomic characterization of asymptomatic CT-detected lung cancers

Author

G. Taliento, S. Javan, Simone Minardi, P G Pelicci, Sara Volorio, Massimo Bellomi, Elena Belloni, Lorenzo Spaggiari, Patrick Maisonneuve, Elisa Venturini, Mirko Riboni, Salvatore Pece, Giuseppe Pelosi, Carla Micucci, Paolo Scanagatta, Giulia Veronesi, Belloni, E, Veronesi, G, Micucci, C, Javan, S, Minardi, Sp, Venturini, E, Maisonneuve, P, Volorio, S, Riboni, M, Bellomi, M, Scanagatta, P, Taliento, G, Pelosi, G, Pece, S, Spaggiari, L, and Pelicci, Pg

Subjects
Cancer Research, Pathology, medicine.medical_specialty, Lung Neoplasms, DNA Copy Number Variations, Population, Single-nucleotide polymorphism, Biology, medicine.disease_cause, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Asymptomatic, Genetics, medicine, Humans, Mass Screening, Copy-number variation, Lung cancer, education, Molecular Biology, Early Detection of Cancer, Aged, Neoplasm Staging, education.field_of_study, Smoking, Cancer, Karyotype, Genes, erbB-1, Sequence Analysis, DNA, Middle Aged, Aneuploidy, Genes, p53, medicine.disease, Genes, ras, Karyotyping, Asymptomatic Diseases, Immunology, medicine.symptom, Tomography, X-Ray Computed, Carcinogenesis
Abstract

http://hdl.handle.net/20.500.11768/96459 Computed tomography (CT) screening of lung cancer allows the detection of early tumors. The objective of our study was to verify whether initial asymptomatic lung cancers, identified by high-resolution low-dose CT (LD-CT) on a high-risk population, show genetic abnormalities that could be indicative of the early events of lung carcinogenesis. We analyzed 78 tumor samples: 21 (pilot population) from heavy smokers with asymptomatic non-screening detected early-stage lung cancers and 57 from 5203 asymptomatic heavy smoker volunteers, who underwent a LD-CT screening study. During surgical resection of the detected tumors, tissue samples were collected and short-term cultures were started for karyotype evaluation. Samples were classified according to the normal (NK) or aneuploid (AK) karyotype. The NK samples were further analyzed by the Affymetrix single-nucleotide polymorphisms (SNPs) technology. Metaphase spreads were obtained in 73.0% of the selected samples: 80.7% showed an AK. A statistically significant correlation was found between presence of vascular invasion and abnormal karyotype. A total of 10 NK samples were suitable for SNPs analysis. Subtle genomic alterations were found in eight tumors, the remaining two showing no evidence to date of chromosomal aberrations anywhere in the genome. Two common regions of amplification were identified at 5p and 8p11. Mutation analysis by direct sequencing was conducted for the K-RAS, TP53 and EGFR genes, confirming data already described for heavy smokers. We show that: (i) the majority of screening-detected tumors are aneuploid; (ii) early-stage tumors tend to harbor a less abnormal karyotype; (iii) whole genome analysis of NK tumors allows for the detection of common regions of copy number variation (such as amplifications at 5p and 8p11), highlighting genes that might be considered candidate markers of early events in lung carcinogenesis. Oncogene (2011) 30, 1117-1126; doi:10.1038/onc.2010.478; published online 25 October 2010

Published
2010
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