1. Psychomotor development of children born after preimplantation genetic diagnosis and parental stress evaluation
- Author
-
Joanne Traeger-Synodinos, Aspasia Destouni, Sophia Kitsiou-Tzeli, Stelios Mantoudis, Elena Critselis, Emmanouel Kanavakis, Loretta Thomaidis, Vassiliki Touliatou, Eleni Leze, Dimitrios Kafetzis, and Hera Drandakis
- Subjects
Adult ,Parents ,Pediatrics ,medicine.medical_specialty ,Cross-sectional study ,Developmental Disabilities ,Preimplantation genetic diagnosis ,Bayley Scales of Infant Development ,Pediatric surgery ,Cognitive development ,Humans ,Medicine ,Cognitive skill ,Child ,Preimplantation Diagnosis ,Psychomotor learning ,Cesarean Section ,business.industry ,Cognition ,respiratory system ,Cross-Sectional Studies ,Motor Skills ,Pediatrics, Perinatology and Child Health ,lipids (amino acids, peptides, and proteins) ,Cognition Disorders ,business ,Stress, Psychological - Abstract
The increasing number of children conceived following preimplantation genetic diagnosis (PGD) necessitates the evaluation of their motor and cognitive development. The primary study objective was to evaluate the physical, developmental, and neurological outcome of children born after PGD in Greece. In addition, the secondary study objective was to compare the stress levels regarding parental roles between parents of PGD children and those of naturally conceived children. A cross-sectional study design was applied. The study population consisted of 31 children (aged 2 months to 7.5 years) born after PGD analysis and their parents. The developmental evaluation of children included a detailed physical evaluation and cognitive assessment with the Bayley Scales of Infant Development. The parent stress index was applied to evaluate comparative parental stress levels between those parents of PGD children and those of naturally conceived healthy children. High rates of caesarean deliveries, increased incidence of prematurity, multiples and low-birth weight were observed among the 31 PGD children. Overall, 24 of the 31 PGD children had cognitive skills within normal range [general developmental quotient (GDQ): 86–115], while 6 children had lower levels of cognitive skills (GDQ
- Published
- 2012
- Full Text
- View/download PDF