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18 results on '"Shigefuku A"'

1. Risk factors for portopulmonary hypertension in patients with cirrhosis: a prospective, multicenter study

Author

Atsukawa, Masanori, primary, Tsubota, Akihito, additional, Kondo, Chisa, additional, Koyano, Kaori-Shioda, additional, Ishikawa, Toru, additional, Toyoda, Hidenori, additional, Takaguchi, Koichi, additional, Watanabe, Tsunamasa, additional, Matsuura, Kentaro, additional, Ogawa, Chikara, additional, Hiraoka, Atsushi, additional, Okubo, Hironao, additional, Tateyama, Masakuni, additional, Uojima, Haruki, additional, Nozaki, Akito, additional, Chuma, Makoto, additional, Kato, Keizo, additional, Mikami, Shigeru, additional, Tani, Joji, additional, Morishita, Asahiro, additional, Kawata, Kazuhito, additional, Tada, Toshifumi, additional, Furuichi, Yoshihiro, additional, Okubo, Tomomi, additional, Kawano, Tadamichi, additional, Arai, Taeang, additional, Kawabe, Naoto, additional, Kawamura, Naohiro, additional, Ikegami, Tadashi, additional, Nakamuta, Makoto, additional, Shigefuku, Ryuta, additional, Iwasa, Motoh, additional, Tanaka, Yasuhito, additional, Hatano, Masaru, additional, and Iwakiri, Katsuhiko, additional

Published
2022
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5. Effects of endoscopic injection sclerotherapy for esophagogastric varices on portal hemodynamics and liver function

Author

Shigefuku, Ryuta, primary, Takahashi, Hideaki, additional, Watanabe, Tsunamasa, additional, Hattori, Nobuhiro, additional, Ikeda, Hiroki, additional, Matsunaga, Kotaro, additional, Ehira, Takuya, additional, Suzuki, Tatsuya, additional, Matsumoto, Nobuyuki, additional, Okuse, Chiaki, additional, Iwasa, Motoh, additional, Nakagawa, Hayato, additional, Itoh, Fumio, additional, and Suzuki, Michihiro, additional

Published
2022
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6. Prognostic Significance of Ground-Glass Opacity Components in 5-Year Survivors With Resected Lung Adenocarcinoma

Author

Masaru Hagiwara, Norihiko Ikeda, Shunsuke Shigefuku, Masatoshi Kakihana, Tatsuo Ohira, Naohiro Kajiwara, and Yoshihisa Shimada

Subjects
medicine.medical_specialty, Lung, Proportional hazards model, business.industry, Incidence (epidemiology), Retrospective cohort study, medicine.disease, Gastroenterology, Ground-glass opacity, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Oncology, Surgical oncology, 030220 oncology & carcinogenesis, Internal medicine, medicine, Adenocarcinoma, 030211 gastroenterology & hepatology, Surgery, Stage (cooking), medicine.symptom, business
Abstract

Reports on the prognosis for 5-year survivors with lung adenocarcinoma after resection are sparse. This study aimed to identify factors associated with overall survival (OS) and cancer-specific survival (CSS) for 5-year survivors with completely resected lung adenocarcinoma, and to determine whether preoperative imaging factors, including the presence of ground-glass opacity (GGO) components, affect late recurrence in long-term survivors. Complete resection of lung adenocarcinoma was performed for 1681 patients between January 2000 and December 2013. Of these patients, 936 who survived 5 years or longer after surgery were identified, and factors associated with OS and CSS were determined using the Cox proportional hazard model. Multivariable analysis demonstrated that lymph node metastasis (p

Published
2020
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7. Significant prognostic determinants in lung cancers of the superior sulcus: comparable analysis of resected and unresected cases

Author

Sachio Maehara, Naohiro Kajiwara, Yujin Kudo, Shunsuke Shigefuku, Masaru Hagiwara, Yoshihisa Shimada, Masatoshi Kakihana, Norihiko Ikeda, Takehiko Tanaka, and Tatsuo Ohira

Subjects
Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lung Neoplasms, Multivariate analysis, 030204 cardiovascular system & hematology, Gastroenterology, 03 medical and health sciences, Pancoast tumor, 0302 clinical medicine, Carcinoembryonic antigen, Japan, Unresected, Surgical oncology, Carcinoma, Non-Small-Cell Lung, Internal medicine, medicine, Humans, Neoplasm Metastasis, Pathological, Aged, Aged, 80 and over, biology, business.industry, Pancoast Syndrome, General Medicine, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Cardiac surgery, Cardiothoracic surgery, 030220 oncology & carcinogenesis, biology.protein, Female, Surgery, Cardiology and Cardiovascular Medicine, business
Abstract

In this study, we aimed to identify prognostic determinants and to comparably analyze clinical features of patients with both resected and unresected superior sulcus tumors (SSTs). The data of 56 patients who underwent any treatment for an SST from 2004 through 2016 in our hospital were reviewed. Overall survival (OS) rates were estimated using the Kaplan–Meier method. Univariate and multivariate analyses were performed to determine independent prognostic factors for patients with resected and unresected SST separately. The number of patients with resected and unresected SSTs was 24 (43%) and 32 (57%), respectively. Of the 24 patients who underwent surgery, 20 received induction therapy, with 32% achieving pathological complete response. Complete resection (R0) was performed in 22 patients (92%). On multivariate survival analysis, preoperative serum carcinoembryonic antigen (CEA) level (median 8.3 ng/ml, p = 0.021) was identified as the independent determinant of OS in surgical patients; whereas, initial treatment response (complete response or partial response, p = 0.032) was the independent OS indicator in non-surgical patients. The 5-year OS of the patient with resected and unresected SST was 68.8% and 29.1% (p = 0.008), respectively. Significant prognostic factors differ among patients stratified by the presence of surgical resection for SSTs. Preoperative CEA level in surgical candidates and initial treatment response in non-surgical patients were the independent factors associated with OS. Surgical candidates are expected to have more favorable survival than patients with unresectable SSTs.

Published
2020
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8. Recurrent hepatocellular carcinoma with osteoclast-like giant cells: a case report

Author

Mone, Tsukimoto, Kazushi, Sugimoto, Ryuta, Shigefuku, Ryosuke, Sugimoto, Hiroto, Yuasa, Katsunori, Uchida, and Norihiko, Yamamoto

Subjects
Male, Carcinoma, Hepatocellular, Liver Neoplasms, Humans, Osteoclasts, General Medicine, Middle Aged, Neoplasm Recurrence, Local, Giant Cells, Aged
Abstract

Background Hepatocellular carcinoma with osteoclast-like giant cells is very rare and has an extremely poor prognosis. Here, we report a case of hepatocellular carcinoma with osteoclast-like giant cells that had a relatively better prognosis. Case presentation A 70-year-old Japanese man with hepatitis B virus-related liver cirrhosis was admitted to our hospital for the treatment of recurrent hepatocellular carcinoma. At the age of 60 years, he was first diagnosed as having hepatocellular carcinoma in the right lobe (9 cm in diameter), and liver resection of segment 7/8 was performed. Histological findings showed well-differentiated hepatocellular carcinoma. Since then, imaging studies have been performed every 3 or 4 months. One year later, hepatocellular carcinoma recurred in the lateral segment, and radiofrequency ablation was performed. Nine years after the first presentation, hepatocellular carcinoma recurrences were detected in the caudate lobe and segment 5 by imaging studies. Surgical resection of the caudate lobe was performed, and ultrasonography-guided radiofrequency ablation was subsequently performed for the segment 5 tumor. The resected tumor was simple nodular, well-differentiated HCC; it measured 21 × 21 mm and contained many osteoclast-like giant cells. As neither vascular nor bile duct invasion was found, we believe that radical resection was achieved. Since then, the hepatocellular carcinoma has not recurred for over a year and a half. Conclusion Hepatocellular carcinoma with osteoclast-like giant cells is very rare and the prognosis is extremely poor, but early detection can lead to a better clinical course.

Published
2022
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14. Esophagogastric varices were diagnosed in a non-cirrhotic liver case during long-term follow-up after oxaliplatin-based chemotherapy

Author

Shigefuku, Ryuta, primary, Watanabe, Tsunamasa, additional, Mizukami, Takuro, additional, Matsunaga, Kotaro, additional, Hattori, Nobuhiro, additional, Ehira, Takuya, additional, Suzuki, Tatsuya, additional, Nakano, Hiroyasu, additional, Sato, Yoshinori, additional, Matsuo, Yasumasa, additional, Nakahara, Kazunari, additional, Ikeda, Hiroki, additional, Matsumoto, Nobuyuki, additional, Tsuda, Takashi, additional, Katayama, Masafumi, additional, Koizumi, Satoshi, additional, Okuse, Chiaki, additional, Suzuki, Michihiro, additional, Otsubo, Takehito, additional, Nakajima, Takako Eguchi, additional, Yasuda, Hiroshi, additional, and Itoh, Fumio, additional

Published
2018
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15. Improvement of high serum levels of biomarkers of endothelial injury after allogeneic hematopoietic SCT with pre-existing severe hepatitis using recombinant human soluble thrombomodulin

Author

Y Inoue, R Shigefuku, M Takahashi, T Saito, H Ikeda, K Sato, C Okuse, Ikuo Miura, and Y Tsuruoka

Subjects
Transplantation, Endothelium, business.industry, medicine.medical_treatment, Hematology, Hematopoietic stem cell transplantation, medicine.disease, law.invention, Haematopoiesis, Graft-versus-host disease, medicine.anatomical_structure, law, Immunology, cardiovascular system, medicine, Recombinant DNA, Stem cell, Progenitor cell, business
Abstract

Improvement of high serum levels of biomarkers of endothelial injury after allogeneic hematopoietic SCT with pre-existing severe hepatitis using recombinant human soluble thrombomodulin

Published
2014
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17. Xenon computed tomography can evaluate the improvement of hepatic hemodynamics before and after endoscopic injection sclerotherapy

Author

Takahashi, Hideaki, primary, Suzuki, Michihiro, additional, Shigefuku, Ryuta, additional, Okano, Miki, additional, Hiraishi, Tetsuya, additional, Takagi, Rei, additional, Noguchi, Yohei, additional, Hattori, Nobuhiro, additional, Hatsugai, Moriaki, additional, Nakahara, Kazunari, additional, Okamoto, Masaru, additional, Kobayashi, Minoru, additional, Ikeda, Hiroki, additional, Fukuda, Yasunobu, additional, Nagase, Yoshihiko, additional, Ishii, Toshiya, additional, Matsunaga, Kotaro, additional, Matsumoto, Nobuyuki, additional, Okuse, Chiaki, additional, Sase, Shigeru, additional, and Itoh, Fumio, additional

Published
2013
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18. Pathophysiological analysis of nonalcoholic fatty liver disease by evaluation of fatty liver changes and blood flow using xenon computed tomography: can early-stage nonalcoholic steatohepatitis be distinguished from simple steatosis?

Author

Shigefuku, Ryuta, primary, Takahashi, Hideaki, additional, Kobayashi, Minoru, additional, Ikeda, Hiroki, additional, Matsunaga, Kotaro, additional, Okuse, Chiaki, additional, Matsumoto, Nobuyuki, additional, Maeyama, Shiro, additional, Sase, Shigeru, additional, Suzuki, Michihiro, additional, and Itoh, Fumio, additional

Published
2012
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