1. Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
- Author
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Irene Andia-Biraro, William Worodria, Robert Buyungo, Joseph Baruch Baluku, Amir Wasswa, Godwin Anguzu, Samuel Ntambi, Sylvia Nassozi, Rose Mulwana, Sharon Namiiro, Febronius Babirye, and Mike Sempiira
- Subjects
Adult ,Male ,0301 basic medicine ,medicine.medical_specialty ,Tuberculosis ,Alcohol Drinking ,Science ,Population ,Human immunodeficiency virus (HIV) ,HIV Infections ,medicine.disease_cause ,Article ,03 medical and health sciences ,0302 clinical medicine ,Alcohol intoxication ,Tuberculosis diagnosis ,Cigarette smoking ,Risk Factors ,Poverty Areas ,Internal medicine ,Prevalence ,Humans ,Mass Screening ,Medicine ,Uganda ,education ,Antibiotics, Antitubercular ,Tuberculosis, Pulmonary ,education.field_of_study ,Multidisciplinary ,High risk populations ,business.industry ,Sputum ,HIV ,Mycobacterium tuberculosis ,medicine.disease ,030104 developmental biology ,Female ,medicine.symptom ,business ,Nucleic Acid Amplification Techniques ,030217 neurology & neurosurgery - Abstract
Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcohol intoxication were excluded. We performed HIV testing using immunochromatographic antibody tests (Alere Determine HIV-1/2 and Chembio HIV 1/2 STAT-PAK). TB was confirmed using the Xpert MTB/RIF Ultra assay, performed on single spot sputum samples. We enrolled 272 participants from 42 bars in 5 slums. The prevalence of HIV and TB was 11.4% (95% CI 8.1–15.8) and 15 (95% CI 6–39) per 1,000 population respectively. Predictors of HIV were female sex (aOR 5.87, 95% CI 2.05–16.83), current cigarette smoking (aOR 3.23, 95% CI 1.02–10.26), history of TB treatment (aOR 10.19, 95% CI 3.17–32.82) and CAGE scores of 2–3 (aOR 3.90, 95% CI 1.11–13.70) and 4 (aOR 4.77, 95% CI 1.07–21.35). The prevalence of HIV and TB was twice and four times the national averages respectively. These findings highlight the need for concurrent programmatic screening for both HIV and TB among high risk populations in slums.
- Published
- 2020
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