1. HIV vaccine design and the neutralizing antibody problem
- Author
-
Wayne C. Koff, Gary J. Nabel, Joseph Sodroski, Robert W. Doms, Ronald C. Desrosiers, Dennis R. Burton, John P. Moore, Richard T. Wyatt, Ian A. Wilson, and Peter D. Kwong
- Subjects
Models, Molecular ,Immunology ,Human immunodeficiency virus (HIV) ,HIV Antibodies ,HIV Envelope Protein gp120 ,medicine.disease_cause ,Epitopes ,Acquired immunodeficiency syndrome (AIDS) ,Neutralization Tests ,medicine ,Humans ,Immunology and Allergy ,HIV vaccine ,Neutralizing antibody ,AIDS Vaccines ,biology ,business.industry ,Antibodies, Monoclonal ,medicine.disease ,Virology ,HIV Envelope Protein gp41 ,Drug Design ,HIV-1 ,biology.protein ,Antibody ,business - Abstract
Eliciting broadly neutralizing antibodies to human immunodeficiency virus could bring closer the goal of a successful AIDS vaccine. Here the International AIDS Vaccine Initiative Neutralizing Antibody Consortium discusses current approaches to overcome the problems faced.
- Published
- 2004