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14 results on '"Ojo Oluwafemi Adeleke"'

4. Correction: Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Author

Nwonuma, Charles O., primary, Nwatu, Victoria C., additional, Mostafa‑Hedeab, Gomaa, additional, Adeyemi, Oluyomi S., additional, Alejolowo, Omokolade O., additional, Ojo, Oluwafemi Adeleke, additional, Adah, Sylvanus A., additional, Awakan, Oluwakemi J., additional, Okolie, Charles E., additional, Asogwa, Nnaemeka Tobechukwu, additional, Udofia, Inemesit A., additional, Egharevba, Godshelp O., additional, Aljarba, Nada H., additional, Alkahtani, Saad, additional, and Batiha, Gaber El‑Saber, additional

Published
2022
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5. Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Author

Nwonuma, Charles O., primary, Nwatu, Victoria C., additional, Mostafa-Hedeab, Gomaa, additional, Adeyemi, Oluyomi S., additional, Alejolowo, Omokolade O., additional, Ojo, Oluwafemi Adeleke, additional, Adah, Sylvanus A., additional, Awakan, Oluwakemi J., additional, Okolie, Charles E., additional, Asogwa, Nnaemeka Tobechukwu, additional, Udofia, Inemesit A., additional, Egharevba, Godshelp O., additional, Aljarba, Nada H., additional, Alkahtani, Saad, additional, and Batiha, Gaber El-Saber, additional

Published
2022
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6. Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats

Author

Essien Precious Ekong, Ajiboye Basiru Olaitan, Kappo Abidemi Paul, Onikanni Sunday Amos, Ojo Oluwafemi Adeleke, and Oyinloye Babatunji Emmanuel

Subjects
medicine.medical_specialty, Pharmaceutical Science, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Nephropathy, chemistry.chemical_compound, Internal medicine, Diabetes mellitus, medicine, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Creatinine, business.industry, Glutathione, 021001 nanoscience & nanotechnology, medicine.disease, Streptozotocin, 0104 chemical sciences, Metformin, Endocrinology, chemistry, Uric acid, Alkaline phosphatase, 0210 nano-technology, business, medicine.drug
Abstract

The ameliorative potential of aqueous leave extract of Sterculia tragacantha on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats were assessed. Forty albino rats (out of fifty) were intraperitoneally induced using 35 mg/kg of streptozotocin, and then grouped into normal control, diabetic control, diabetic animals received 150 and 300 mg/kg of aqueous extract of S. tragacantha leaves (AESTL) and diabetic animals placed on 200 mg/kg of metformin. This experiment lasted for two weeks, animals were sacrificed, and a series of biochemical indices were evaluated. Diabetic rats receiving AESTL revealed a momentous decline in fasting blood glucose, urea, creatinine, uric acid, and alkaline phosphatase levels. Administration of AESTL to diabetic animals considerably improved the activities of SOD, CAT, GPx, GST, and GSH with a decline in MDA levels. Also, AESTL reversed abnormalities in mRNA gene expressions of IL-1β, TGF-1β, KIM-1, EPO and CASP 6 in diabetic rats placed on AESTL treatment. The excellent results of diabetic rats maintained on AESTL were supported by histological findings in this study. Hence, AESTL may have beneficial effects in controlling nephropathy associated with diabetes mellitus.

Published
2020
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7. Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway

Author

Ojo, Oluwafemi Adeleke, primary, Amanze, Jennifer Chidubem, additional, Oni, Abosede Itunuoluwa, additional, Grant, Susan, additional, Iyobhebhe, Matthew, additional, Elebiyo, Tobiloba Christiana, additional, Rotimi, Damilare, additional, Asogwa, Nnaemeka Tobechukwu, additional, Oyinloye, Babatunji Emmanuel, additional, Ajiboye, Basiru Olaitan, additional, and Ojo, Adebola Busola, additional

Published
2022
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8. Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations

Author

Khan, Muhammad Idrees, primary, Bouyahya, Abdelhakim, additional, Hachlafi, Naoufal E. L., additional, Menyiy, Naoual El, additional, Akram, Muhammad, additional, Sultana, Sabira, additional, Zengin, Gokhan, additional, Ponomareva, Lilya, additional, Shariati, Mohammad Ali, additional, Ojo, Oluwafemi Adeleke, additional, Dall’Acqua, Stefano, additional, and Elebiyo, Tobiloba Christiana, additional

Published
2022
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14. Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats

Author

Ojo, Oluwafemi Adeleke, primary, Ojo, Adebola Busola, additional, Oyinloye, Babatunji Emmanuel, additional, Ajiboye, Basiru Olaitan, additional, Anifowose, Omosola Olufisayo, additional, Akawa, Ayodeji, additional, Olaiya, Oluranti Esther, additional, Olasehinde, Oluwaseun Ruth, additional, and Kappo, Abidemi Paul, additional

Published
2019
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