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4. Are dietary supplements and nutraceuticals effective for musculoskeletal health and cognitive function? A scoping review

Author

Iolascon, G., primary, Gimigliano, R., additional, Bianco, M., additional, de Sire, A., additional, Moretti, A., additional, Giusti, A., additional, Malavolta, N., additional, Migliaccio, S., additional, Migliore, A., additional, Napoli, N., additional, Piscitelli, P., additional, Resmini, G., additional, Tarantino, U., additional, and Gimigliano, F., additional more...

Published
2016
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6. Erratum to: Taxonomy of rare genetic metabolic bone disorders

Author

Masi, L., primary, Agnusdei, D., additional, Bilezikian, J., additional, Chappard, D., additional, Chapurlat, R., additional, Cianferotti, L., additional, Devolgelaer, J.-P., additional, El Maghraoui, A., additional, Ferrari, S., additional, Javaid, K., additional, Kaufman, J.-M., additional, Liberman, U. A., additional, Lyritis, G., additional, Miller, P., additional, Napoli, N., additional, Roldan, E., additional, Papapoulos, S., additional, Watts, N. B., additional, and Brandi, M. L., additional more...

Published
2015
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7. Serum chitotriosidase in postmenopausal women with severe osteoporosis

Author

Musumeci, M., primary, Palermo, A., additional, D’Onofrio, L., additional, Vadalà, G., additional, Greto, V., additional, Di Stasio, E., additional, Maddaloni, E., additional, Di Rosa, M., additional, Tibullo, D., additional, Silvia, A., additional, Napoli, N., additional, Denaro, V., additional, and Manfrini, S., additional more...

Published
2015
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8. Taxonomy of rare genetic metabolic bone disorders

Author

Masi, L., primary, Agnusdei, D., additional, Bilezikian, J., additional, Chappard, D., additional, Chapurlat, R., additional, Cianferotti, L., additional, Devolgelaer, J.-P., additional, El Maghraoui, A., additional, Ferrari, S., additional, Javaid, M. K., additional, Kaufman, J.-M., additional, Liberman, U. A., additional, Lyritis, G., additional, Miller, P., additional, Napoli, N., additional, Roldan, E., additional, Papapoulos, S., additional, Watts, N. B., additional, and Brandi, M. L., additional more...

Published
2015
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16. Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report

Author

Rizzoli, R., primary, Åkesson, K., additional, Bouxsein, M., additional, Kanis, J. A., additional, Napoli, N., additional, Papapoulos, S., additional, Reginster, J.-Y., additional, and Cooper, C., additional more...

Published
2010
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23. FokI Polymorphism of the Vitamin D Receptor Gene Correlates with Parameters of Bone Mass and Turnover in a Female Population of the Italian Island of Lampedusa

Author

Falchetti, A., primary, Sferrazza, C., additional, Cepollaro, C., additional, Gozzini, A., additional, Del Monte, F., additional, Masi, L., additional, Napoli, N., additional, Di Fede, G., additional, Cannone, V., additional, Cusumano, G., additional, Pandolfo, M. C., additional, Rini, G. B., additional, Tanini, A., additional, and Brandi, M. L., additional more...

Published
2006
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25. Short- and Long-term Outcomes after Robotic and Laparoscopic Liver Resection for Malignancies: A Propensity Score-Matched Study

Author

Eylon Lahat, Ugo Boggi, Antonella Tudisco, Chetana Lim, Claudio Ricci, Chady Salloum, Daniel Azoulay, Michael Osseis, Niccolò Napoli, Lim C., Salloum C., Tudisco A., Ricci C., Osseis M., Napoli N., Lahat E., Boggi U., and Azoulay D. more...

Subjects
Male, Laparoscopic surgery, medicine.medical_specialty, Carcinoma, Hepatocellular, Blood transfusion, Matched-Pair Analysis, medicine.medical_treatment, 03 medical and health sciences, 0302 clinical medicine, Robotic Surgical Procedures, medicine, Hepatectomy, Humans, Blood Transfusion, Propensity Score, Survival rate, Aged, Female, Length of Stay, Liver Neoplasms, Margins of Excision, Middle Aged, Laparoscopy, business.industry, Carcinoma, Hepatocellular, robotic surgery, laparoscopic surgery, Surgery, Cardiac surgery, Cardiothoracic surgery, 030220 oncology & carcinogenesis, Propensity score matching, Resection margin, 030211 gastroenterology & hepatology, business, Abdominal surgery
Abstract

Objectives: A laparoscopic approach improves short-term outcomes and maintains long-term outcomes compared to an open approach. In turn, the recent development of robotic surgery raises the question whether it performs as well as laparoscopic surgery. The aim of this study was to compare the short- and long-term outcomes of laparoscopic liver resection (LLR) and robotic liver resection (RLR) for malignancies. Method: From 2011 to 2017, the study population included 111 patients in the LLR group and 61 in the RLR group. Short- and long-term outcomes were compared before and after propensity score matching (PSM). Results: Operative mortality rate was nil. The intraoperative blood transfusion rate was higher during RLR (15% vs. 2%, p = 0.0009). Major morbidity and hospital stay were not different between the two groups. The resection margin width (LLR 7mm vs. RLR 10mm, p = 0.13) and R1 resection rates (resection margin width < 1mm; LLR 15% vs. RLR 11%, p = 0.49) were similar. After PSM (55 patients in each group), the blood transfusion, major morbidity, hospital stay and R1 resection were similar between the two groups. When considering the largest subset of patients with hepatocellular carcinoma including 114 patients (66%), the 3-year overall survival rate was 80% in the LLR group and 97% in the RLR group (p = 0.10) and remained similar after PSM (p = 0.27). The 3-year recurrence-free survival rate was 50% in the LLR group and 64% in the RLR group (p = 0.30) and remained similar after PSM (p = 0.26). Conclusions: No differences were found in blood transfusion, incidence of positive resection margins and long-term outcomes between the two techniques. RLR does not compromise short-term and oncologic outcomes in patients with liver cancers. more...

Published
2019
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26. FokI Polymorphism of the Vitamin D Receptor Gene Correlates with Parameters of Bone Mass and Turnover in a Female Population of the Italian Island of Lampedusa

Author

Gaspare Cusumano, Chiara Cepollaro, M. C. Pandolfo, Nicola Napoli, Alessia Gozzini, M. L. Brandi, F. Del Monte, Giovam Battista Rini, Laura Masi, Valentina Cannone, G. Di Fede, Annalisa Tanini, C. Sferrazza, Alberto Falchetti, FALCHETTI A, SFERRAZZA C, CEPOLLARO C, GOZZINI A, DEL MONTE F, MASI L, NAPOLI N, DI FEDE G, CANNONE V, CUSUMANO G, PANDOLFO MC, RINI GB, TANINI A, and BRANDI ML more...

Subjects
medicine.medical_specialty, Genotype, Bone density, Endocrinology, Diabetes and Metabolism, Osteoporosis, Calcitriol receptor, Bone and Bones, White People, Cohort Studies, FokI polymorphism of the vitamin D, Endocrinology, Gene Frequency, Bone Density, Risk Factors, Internal medicine, medicine, Humans, Orthopedics and Sports Medicine, Allele frequency, Osteoporosis, Postmenopausal, Ultrasonography, Polymorphism, Genetic, biology, Exons, Middle Aged, medicine.disease, FokI, Postmenopause, Italy, Premenopause, Osteocalcin, biology.protein, Receptors, Calcitriol, Female, Gene polymorphism
Abstract

One of the most promising genetic approaches to dissecting a multifactorial disease is represented by genetically isolated population studies. We studied a genetic marker in a cohort of women living on the Mediterranean island of Lampedusa, a geographically isolated population. Lampedusa, located between the African coast and Sicily, consists of a young genetic isolate ( more...

Published
2006
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27. Hypogonadism and Hormone Replacement Therapy on Bone Mass of Adult Women with Thalassemia Major

Author

G. Di Fede, Enrico Carmina, Nicola Napoli, G. Renda, C. Lo Pinto, Giustina Vitale, R. Malizia, Dario Bruno, Giovan Battista Rini, CARMINA E, DI FEDE G, NAPOLI N, RENDA G, G VITALE, LO PINTO C, BRUNO D, MALIZIA R, and RINI GB more...

Subjects
Adult, medicine.medical_specialty, Hormone Replacement Therapy, Endocrinology, Diabetes and Metabolism, Thalassemia, Osteoporosis, Bone remodeling, Adult women, Endocrinology, Sex hormone-binding globulin, Bone Density, Internal medicine, medicine, Humans, Orthopedics and Sports Medicine, Femoral neck, Estradiol, biology, business.industry, Hypogonadism, beta-Thalassemia, Osteoporosi, Luteinizing Hormone, medicine.disease, Thalassaemia, medicine.anatomical_structure, Transgender hormone therapy, Orthopedic surgery, biology.protein, Female, Follicle Stimulating Hormone, business
Abstract

We studied bone mass and metabolism in 30 adult women (age 28.5 +/- 1.3) with thalassemia major (TM) and evaluated whether prolonged hormone replacement therapy (HRT) was able to optimize bone accrual. TM patients had reduced bone mass, increased bone turnover and lower serum gonadotropin and estradiol levels compared with 10 normal women of similar age. A significant correlation was found between bone mass and sex hormone levels. Six TM patients with normal ovarian function had normal bone turnover markers and modestly low bone mass (lumbar spine -1.29 +/- 0.31; femoral neck -0.60+/-0.21; Z-score). The other 24 TM women were hypogonadic and had significantly lower bone mass for age (lumbar spine -2.35 +/- 0.2, femoral neck -1.83 +/- 0.2) and increased bone turnover relative to eugonadal women. Of the hypogonadal patients, 13 had taken HRT since age 15 +/- 1 years, but their bone mass and turnover markers were not different than untreated hypogonadal patients. In conclusion, while hypogonadism negatively affects bone mass acquisition in adult TM women, HRT at the standard replacement doses is not sufficient to secure optimal bone accrual. more...

Published
2003
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