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119 results on '"Morton R"'

3. Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300

Author

Boissinot, M., primary, King, H., additional, Adams, M., additional, Higgins, J., additional, Shaw, G., additional, Ward, T. A., additional, Steele, L. P., additional, Tams, D., additional, Morton, R., additional, Polson, E., additional, da Silva, B., additional, Droop, A., additional, Hayes, J. L., additional, Martin, H., additional, Laslo, P., additional, Morrison, E., additional, Tomlinson, D. C., additional, Wurdak, H., additional, Bond, J., additional, Lawler, S. E., additional, and Short, S. C., additional

Published
2020
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45. The International Register of Lithium Babies

Author

Morton R. Weinstein

Subjects
Pediatrics, medicine.medical_specialty, Lithium (medication), International Cooperation, MEDLINE, Pharmacology (nursing), Lithium, 030226 pharmacology & pharmacy, 01 natural sciences, 010104 statistics & probability, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Drug Guides, Humans, Medicine, Pharmacology (medical), Registries, 0101 mathematics, business.industry, Public Health, Environmental and Occupational Health, Abnormalities, Drug-Induced, Teratogens, Register (music), Female, business, medicine.drug
Published
1976
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46. Lipoprotein Lipase Activity and Blood Triglyceride Levels in Fetal and Newborn Rats

Author

Hall Canter, Morton R. Simon, Margit Hamosh, and Paul Hamosh

Subjects
Male, medicine.medical_specialty, Adipose tissue, chemistry.chemical_compound, Fetus, Internal medicine, medicine, Animals, Lung, Triglycerides, Epididymis, Lipoprotein lipase, biology, Triglyceride, business.industry, Myocardium, Body Weight, Age Factors, Organ Size, Enzyme assay, Rats, Lipoprotein Lipase, Endocrinology, medicine.anatomical_structure, Adipose Tissue, chemistry, In utero, Pediatrics, Perinatology and Child Health, biology.protein, Gestation, Female, business, Omentum
Abstract

Summary: Lipoprotein lipase activity in lung and heart was studied in fetal (17-22 days of gestation) and newborn rats from the day of birth until 30 days of age. Enzyme activity in epididymal, omental, and parametrial adipose tissue was tested after 18 days of age. Blood triglyceride levels were measured at all ages from 17 days in utero until 30 days after birth. The developmental pattern of lipoprotein lipase differed markedly in lung and heart. Although lipoprotein lipase activity was 4 to 5 times higher hi adult rat heart than in lung (30-40 U/g in heart vs. 8-11 U/g in lung), the activity was almost completely absent from fetal heart and was very low during the first 3 days after birth. Lipoprotein lipase reached 60-70% of adult activity at 6 days and remained at that level until 19 days after birth; adult activity levels were reached at 24 days. In the lung, contrary to the heart, lipoprotein lipase activity was high in the fetus (84% of adult activity), decreased immediately after birth to 45% of adult activity at 2 days, and remained at that level up to 15 days after birth. Enzyme activity started to rise again at 15 days and reached adult levels at 21 days of age. Adipose tissue was present in trace amounts before the age of 2 weeks. In the three fat depots tested, lipoprotein lipase activity was 50% lower than in adults between 20 and 30 days after birth. Blood triglyceride levels increased 4- fold between 2 to 10 hr after birth and remained elevated during the first 3 days after birth. Speculation: The triglyceridemia that starts in the immediate postnatal period and lasts for several days in the rat probably results from the combination of high fat intake and low clearing ability of the extrahepatic tissues. In addition to its role in clearing circulating triglyceride, lipoprotein lipase may play a role in the growth and maturation of individual organs. The present study shows that lipoprotein lipase activity is high in fetal lung during the period of marked surfactant synthesis and suggests that circulating triglyceride-fatty acids are used by the fetal lung for surfactant synthesis.

Published
1978
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47. Clinical applications of the Argon and carbon dioxide lasers in dermatology and plastic surgery

Author

Morton R. Maser, Harvey Lash, and David B. Apfelberg

Subjects
medicine.medical_specialty, Skin Neoplasms, Gas laser, Port wine, Dermatologic Surgical Procedures, chemistry.chemical_element, Skin Diseases, law.invention, Hemangioma, chemistry.chemical_compound, law, medicine, Humans, Argon, Surgery, Plastic, business.industry, Carbon Dioxide, medicine.disease, Laser, Dermatology, eye diseases, Plastic surgery, chemistry, Carbon dioxide, Surgery, Laser Therapy, sense organs, Skin lesion, business
Abstract

Since the 1960's, thousands of skin and soft tissue malformations have been treated with the Argon and carbon dioxide lasers. The Argon laser, emitting blue-green light, is very useful for treating port wine hemangiomas and other cutaneous vascular abnormalities; it has also been applied to a variety of nonvascular skin lesions. Its mechanism of action is essentially heat coagulation.

Published
1983
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