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Your search keyword '"Milyausha S. Kadyrova"' showing total 2 results
Start Over Author "Milyausha S. Kadyrova" Publisher springer science and business media llc
2 results on '"Milyausha S. Kadyrova"'

1. The Dimroth Rearrangement in the Synthesis of Condensed Pyrimidines – Structural Analogs of Antiviral Compounds

Author

Nataliya А. Zhukova, Vakhid А. Mamedov, and Milyausha S. Kadyrova

Subjects
imidazo[1,2-a]pyrimidines, 010405 organic chemistry, Chemistry, Organic Chemistry, pyrazolo[3,4-d]pyrimidines, thieno[2,3-d]pyrimidines, 010402 general chemistry, 01 natural sciences, Dimroth rearrangement, Article, 0104 chemical sciences, [1,2,4]triazolo[1,5-a]pyrimidines, pyrrolo[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines, furo[2,3-d]pyrimidines, antiviral activity, Organic chemistry, purines, quinazolin(on)es
Abstract

The review discusses the use of the Dimroth rearrangement in the synthesis of condensed pyrimidines which are key structural fragments of antiviral agents. The main attention is given to publications over the past 10 years. The bibliography includes 107 references.

Published
2021
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2. New method for the synthesis of 2-substituted benzimidazole-5(6)-carboxylic acids

Author

Il'dar Kh. Rizvanov, Shamil K. Latypov, Victor V. Syakaev, Nataliya A. Zhukova, Tat'yana N. Beschastnova, Vakhid A. Mamedov, and Milyausha S. Kadyrova

Subjects
Benzimidazole, chemistry.chemical_compound, 010405 organic chemistry, Chemistry, Group (periodic table), Product (mathematics), Organic Chemistry, Rearrangement reaction, 010402 general chemistry, 01 natural sciences, Tautomer, Medicinal chemistry, 0104 chemical sciences
Abstract

A new method is proposed for the synthesis of 2-substituted benzimidazole-5(6)-carboxylic acids. The acid-catalyzed rearrangement of 2(3)-aroyl-3(2)-oxo-3,4(1,2)-dihydroquinoxaline-6-carboxylic acids was shown to proceed with the formation of 2-(3-arylquinoxalin-2-yl)-1H-benzimidazole-5(6)-carboxylic acids. NMR studies of the rearrangement reaction product, 2-(3-phenylquinoxalin-2-yl)-1Hbenzimidazole-6-carboxylic acid, indicated that it existed as a mixture of two tautomeric forms due to benzimidazole tautomerism under the NMR conditions. The carboxyl group of the synthesized benzimidazoles was used for the preparation of new derivatives.

Published
2017
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