1. Single-dose treatment with netilmicin for different clinical forms of urinary tract infections
- Author
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J Hnátek, Matousovic K, M Hatala, Liska M, Milotová Z, Horcicková M, and V Prát
- Subjects
Adult ,Male ,Microbiology (medical) ,medicine.medical_specialty ,medicine.drug_class ,Urinary system ,medicine.medical_treatment ,Antibiotics ,Injections, Intramuscular ,Gastroenterology ,Internal medicine ,Single dose treatment ,medicine ,Humans ,Netilmicin ,Aged ,Chemotherapy ,business.industry ,General Medicine ,Middle Aged ,Surgery ,Infectious Diseases ,Renal transplant ,Urinary Tract Infections ,Female ,Gentamicin ,Gentamicins ,business ,medicine.drug - Abstract
A group of 44 patients with various clinical forms of urinary tract infections received a single dose of 300 mg netilmicin i.m. The treatment was efficacious in all patients with infections which were negative in the antibody-coated bacteria test and not complicated by anatomic and/or functional abnormalities of the kidneys and urinary tract. After three weeks the recurrence rate was only 19%. Single-dose treatment also proved very effective against urinary tract infections in renal transplant patients whose infection is almost always located in the lower urinary tract. In contrast, the short-term results of treatment were much poorer in complicated infections and particularly in urinary tract infections which were positive in the anti-body-coated bacteria test; here, the recurrence rate was 67%.
- Published
- 1984
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