1. Comparison of outflow facility before and after the microhook ab interno trabeculotomy
- Author
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Mihoko Mochiji, Aika Tsutsui, Kaoru Manabe, and Masaki Tanito
- Subjects
Intraocular pressure ,medicine.medical_specialty ,genetic structures ,Ocular Hypotension ,Trabeculectomy ,Mixed effects regression ,Article ,03 medical and health sciences ,0302 clinical medicine ,Trabecular Meshwork ,Ophthalmology ,Linear regression ,Humans ,Medicine ,Outflow resistance ,Intraocular Pressure ,Aged ,Retrospective Studies ,business.industry ,Aqueous humour ,Middle Aged ,Trabeculotomy ,eye diseases ,Treatment Outcome ,030221 ophthalmology & optometry ,Outflow ,business ,030217 neurology & neurosurgery ,Student's t-test - Abstract
PURPOSES: To elucidate the mechanism of intraocular pressure (IOP) reduction by microhook ab interno trabeculotomy (μLOT), the aqueous humour outflow facility was compared preoperatively and post-operatively. METHODS: Fifty-one eyes (37 patients; mean age, 67.2 ± 11.8 years) were included. The IOP, number of medications and outflow facility coefficient (C) estimated by pneumatonography were compared preoperatively and post-operatively using the paired t test. Linear regression analysis was performed to identify possible correlations between the C value and IOP or number of medications. To adjust for biases from including both eyes of a patient and differences in background, the preoperative and post-operative C values were compared using a mixed effects regression model. RESULTS: The mean preoperative IOP (18.2 mmHg) and mean number of medications (2.8) decreased significantly post-operatively by 26% and 18%, respectively, to 13.5 mmHg and 2.3 (p
- Published
- 2021
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