Search

Modern myoelectric prosthetic hands have multiple independently controllable degrees of freedom, but require constant visual attention to use effectively. Somatosensory feedback provides information not available through vision alone and is essential for fine motor control of our limbs. Similarly, stimulation of the nervous system can potentially provide artificial somatosensory feedback to reduce the reliance on visual cues to efficiently operate prosthetic devices. We have shown previously that epidural stimulation of the lateral cervical spinal cord can evoke tactile sensations perceived as emanating from the missing arm and hand in people with upper-limb amputation. In this case study, two subjects with upper-limb amputation used this somatotopically-matched tactile feedback to discriminate object size and compliance while controlling a prosthetic hand. With less than 30 min of practice each day, both subjects were able to use artificial somatosensory feedback to perform a subset of the discrimination tasks at a success level well above chance. Subject 1 was consistently more adept at determining object size (74% accuracy; chance: 33%) while Subject 2 achieved a higher accuracy level in determining object compliance (60% accuracy; chance 33%). In each subject, discrimination of the other object property was only slightly above or at chance level suggesting that the task design and stimulation encoding scheme are important determinants of which object property could be reliably identified. Our observations suggest that changes in the intensity of artificial somatosensory feedback provided via spinal cord stimulation can be readily used to infer information about object properties with minimal training.

Background The application of rehabilitation robots has grown during the last decade. While meta-analyses have shown beneficial effects of robotic interventions for some patient groups, the evidence is less in others. We established the Advanced Robotic Therapy Integrated Centers (ARTIC) network with the goal of advancing the science and clinical practice of rehabilitation robotics. The investigators hope to exploit variations in practice to learn about current clinical application and outcomes. The aim of this paper is to introduce the ARTIC network to the clinical and research community, present the initial data set and its characteristics and compare the outcome data collected so far with data from prior studies. Methods ARTIC is a pragmatic observational study of clinical care. The database includes patients with various neurological and gait deficits who used the driven gait orthosis Lokomat® as part of their treatment. Patient characteristics, diagnosis-specific information, and indicators of impairment severity are collected. Core clinical assessments include the 10-Meter Walk Test and the Goal Attainment Scaling. Data from each Lokomat® training session are automatically collected. Results At time of analysis, the database contained data collected from 595 patients (cerebral palsy: n = 208; stroke: n = 129; spinal cord injury: n = 93; traumatic brain injury: n = 39; and various other diagnoses: n = 126). At onset, average walking speeds were slow. The training intensity increased from the first to the final therapy session and most patients achieved their goals. Conclusions The characteristics of the patients matched epidemiological data for the target populations. When patient characteristics differed from epidemiological data, this was mainly due to the selection criteria used to assess eligibility for Lokomat® training. While patients included in randomized controlled interventional trials have to fulfill many inclusion and exclusion criteria, the only selection criteria applying to patients in the ARTIC database are those required for use of the Lokomat®. We suggest that the ARTIC network offers an opportunity to investigate the clinical application and effectiveness of rehabilitation technologies for various diagnoses. Due to the standardization of assessments and the use of a common technology, this network could serve as a basis for researchers interested in specific interventional studies expanding beyond the Lokomat®.

Volumetric muscle loss (VML) is a severe and debilitating clinical problem. Current standard of care includes physical therapy or orthotics, which do not correct underlying strength deficits, and surgical tendon transfers or muscle transfers, which involve donor site morbidity and fall short of restoring function. The results of a 13-patient cohort study are described herein and involve a regenerative medicine approach for VML treatment. Acellular bioscaffolds composed of mammalian extracellular matrix (ECM) were implanted and combined with aggressive and early physical therapy following treatment. Immunolabeling of ultrasound-guided biopsies, and magnetic resonance imaging and computed tomography imaging were performed to analyse the presence of stem/progenitor cells and formation of new skeletal muscle. Force production, range-of-motion and functional task performance were analysed by physical therapists. Electrodiagnostic evaluation was used to analyse presence of innervated skeletal muscle. This study is registered with ClinicalTrials.gov, numbers NCT01292876. In vivo remodelling of ECM bioscaffolds was associated with mobilisation of perivascular stem cells; formation of new, vascularised, innervated islands of skeletal muscle within the implantation site; increased force production; and improved functional task performance when compared with pre-operative performance. Compared with pre-operative performance, by 6 months after ECM implantation, patients showed an average improvement of 37.3% (PP

Two-way factorial mixed design, the between-subjects factor as the spinal cord injury (SCI) status (SCI and non-SCI) and the within-subjects factor as the pressure pattern (alternating and constant pressures).To compare the effects of alternating and constant pressures on weight-bearing tissue perfusion in people with SCI, with application for improving alternating pressure support surface usage.University research laboratory.A total of 28 participants were studied, 7 participants with cervical injury, 7 participants with injury below T6 and 14 healthy controls.Sacral skin perfusion was continuously measured using laser Doppler flowmetry under 10 min preloading, 20 min loading (alternating or constant pressures) and 10 min postloading. Alternating pressure was applied with low-interface pressure at 0 mm Hg and high-interface pressure at 60 mm Hg with a cycle time of 5 min; constant pressure was applied with interface pressure at 30 mm Hg.The results showed that pressure pattern affects skin perfusion responses in weight-bearing tissues (P0.01). Alternating pressure stimulates an increase in skin perfusion (1.21 ± 0.08 au) as compared with constant pressure (0.74 ± 0.07 au) in people with SCI (P0.01). There was no overall difference in the skin perfusion responses of patients with SCI as compared with non-SCI patients (P0.05).This study has shown that alternating pressure enhances the skin perfusion of weight-bearing tissues as compared with constant pressure in people with SCI. The protocol tested in this study may be used to guide the selection of parameters of commercial alternating pressure support surfaces for preventing pressure ulcers in people with SCI.

Cross-sectional study. The purpose of this study was to examine stroke characteristics of long-term manual wheelchair users during an extended manual wheelchair propulsion trial and the extent to which changes in propulsion biomechanics occurred. Human Engineering Research Laboratories, VA Rehabilitation Research and Development Center, VA Pittsburgh Healthcare Systems, Pittsburgh, PA, USA. Kinetic data were recorded from 21 subjects with paraplegia at four time points over the course of a 10-min propulsion trial at a steady state speed of 1.4 m s−1. Upper extremity kinetic parameters were recorded using Smartwheels, force and torque sensing pushrims. Subjects for propulsion biomechanics changed from early to late during the 10-min trial. Individuals displayed decreased maximum rate of rise of resultant force (P=0.0045) with a simultaneous increase in push time (P=0.043) and stroke time (P=0.023), whereas stroke frequency remained static. In addition, there was a decrease in out of plane moment application (P=0.032). Individuals seemed to naturally accommodate their propulsive stroke, using less injurious propulsion biomechanics over the course of a 10-minute trial on a dynamometer. The findings may have occurred as a result of both biomechanical compensations to a challenging propulsion trial and accommodation to propelling on a dynamometer. These results suggest that subjects may be capable of independently incorporating favorable biomechanical strategies to meet the demands of a challenging propulsion scenario.

Individuals who propel wheelchairs have a high prevalence of upper extremity injuries. To better understand the mechanism behind these injuries this study investigates the motion of the shoulder and elbow during wheelchair propulsion. The objectives of this study are: (1) To describe the motion occurring at the shoulder and elbow in anatomical terms during wheelchair propulsion; (2) to obtain variables that characterize shoulder and elbow motion and are statistically stable; (3) to determine how these variables change with speed. The participants in the study were a convenience sample of Paralympic athletes who use manual wheelchairs for mobility and have unimpaired arm function. Each subject propelled an ultralight wheelchair on a dynamometer at 1.3 and 2.2 meters per second (m/s). Biomechanical data was obtained using a force and moment sensing pushrim and a motion analysis system. The main outcome measures investigated were: maximum and minimum angles while in contact with the pushrim, range of motion during the entire stroke and peak accelerations. All of the measures were found to be stable at both speeds (Cronbach's alpha > 0.8). The following measures were found to differ with speed (data format: measure at 1.3 m/s +/- SD; measure at 2.2 m/s +/- SD): minimum shoulder abduction angle during propulsion (24.5 degrees +/- 6.7, 21.6 degrees +/- 7.2), range of motion during the entire stroke in elbow flexion/extension (54.0 degrees +/- 9.9, 58.1 degrees +/- 10.4) and shoulder sagittal flexion/extension (74.8 degrees +/- 9.4, 82.6 degrees +/- 8.5), and peak acceleration in shoulder sagittal flexion/extension (4044 degrees/s2 +/- 946, 7146 degrees/s2 +/- 1705), abduction/adduction (2678 degrees/s2 +/- 767, 4928 degrees/s2 +/- 1311), and elbow flexion/extension (9355 degrees/s2 +/- 4120, 12889 degrees/s2 +/- 5572). This study described the motion occurring at the shoulder and elbow using a local coordinate system. Stable parameters that characterize the propulsive stroke and differed with speed were found. In the future these same parameters may provide insight into the cause and prevention of shoulder and elbow injuries in manual wheelchair.

Wheelchair pushrim kinetics: Body weight and median nerve function [Archives of Physical Medicine and Rehabilitation 1999;80(8):910-5]