1. Fetal mouse weights and albumin/α1-fetoprotein ratios after maternal infection with Coxsackievirus B3
- Author
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M. J. R. Healy, C. R. Coid, and D. B. Ramsden
- Subjects
Fetal Proteins ,Microbiology (medical) ,Litter (animal) ,Immunology ,Coxsackievirus Infections ,Alpha (ethology) ,Immunoelectrophoresis ,Biology ,Virus ,Andrology ,Embryonic and Fetal Development ,Mice ,Fetus ,Pregnancy ,medicine ,Animals ,Immunology and Allergy ,Pregnancy Complications, Infectious ,Serum Albumin ,medicine.diagnostic_test ,Body Weight ,Albumin ,food and beverages ,General Medicine ,medicine.disease ,Disease Models, Animal ,Animals, Newborn ,Coxsackievirus b3 ,Female - Abstract
The injection of pregnant mice with Coxsackievirus B3 results in a reduction of fetal weights and retarded development of the albumin/α1-fetoprotein ratio which can be measured by using the Laurell two-dimensional immunoelectrophoretic technique. The litter weights tended to be lower in litters with a low albumin/α1-fetoprotein ratio and from an analysis of covariance the results indicate that the effect of the virus on fetal weights can not all be accounted for by the effect on maturation.
- Published
- 1974
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