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4. Identification of early predictors for infected necrosis in acute pancreatitis

Author

Wiese, Mats L., primary, Urban, Steffi, additional, von Rheinbaben, Sabrina, additional, Frost, Fabian, additional, Sendler, Matthias, additional, Weiss, Frank Ulrich, additional, Bülow, Robin, additional, Kromrey, Marie-Luise, additional, Tran, Quang Trung, additional, Lerch, Markus M., additional, Schauer, Birgit, additional, and Aghdassi, Ali A., additional

Published
2022
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6. In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response

Author

Glaubitz, Juliane, primary, Wilden, Anika, additional, Golchert, Janine, additional, Homuth, Georg, additional, Völker, Uwe, additional, Bröker, Barbara M., additional, Thiele, Thomas, additional, Lerch, Markus M., additional, Mayerle, Julia, additional, Aghdassi, Ali A., additional, Weiss, Frank U., additional, and Sendler, Matthias, additional

Published
2022
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11. Association of hepatic steatosis derived from ultrasound and quantitative MRI with prediabetes in the general population

Author

Naeem, Muhammad, primary, Bülow, Robin, additional, Schipf, Sabine, additional, Werner, Nicole, additional, Dörr, Marcus, additional, Lerch, Markus M., additional, Kühn, Jens-Peter, additional, Rathmann, Wolfgang, additional, Nauck, Matthias, additional, Markus, Marcello Ricardo Paulista, additional, Ittermann, Till, additional, and Völzke, Henry, additional

Published
2021
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12. Carrying asymptomatic gallstones is not associated with changes in intestinal microbiota composition and diversity but cholecystectomy with significant dysbiosis

Author

Frost, Fabian, primary, Kacprowski, Tim, additional, Rühlemann, Malte, additional, Weiss, Stefan, additional, Bang, Corinna, additional, Franke, Andre, additional, Pietzner, Maik, additional, Aghdassi, Ali A., additional, Sendler, Matthias, additional, Völker, Uwe, additional, Völzke, Henry, additional, Mayerle, Julia, additional, Weiss, Frank U., additional, Homuth, Georg, additional, and Lerch, Markus M., additional

Published
2021
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13. Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome

Author

Rühlemann, Malte Christoph, primary, Hermes, Britt Marie, additional, Bang, Corinna, additional, Doms, Shauni, additional, Moitinho-Silva, Lucas, additional, Thingholm, Louise Bruun, additional, Frost, Fabian, additional, Degenhardt, Frauke, additional, Wittig, Michael, additional, Kässens, Jan, additional, Weiss, Frank Ulrich, additional, Peters, Annette, additional, Neuhaus, Klaus, additional, Völker, Uwe, additional, Völzke, Henry, additional, Homuth, Georg, additional, Weiss, Stefan, additional, Grallert, Harald, additional, Laudes, Matthias, additional, Lieb, Wolfgang, additional, Haller, Dirk, additional, Lerch, Markus M., additional, Baines, John F., additional, and Franke, Andre, additional

Published
2021
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14. Large-scale association analyses identify host factors influencing human gut microbiome composition

Author

Kurilshikov, Alexander, primary, Medina-Gomez, Carolina, additional, Bacigalupe, Rodrigo, additional, Radjabzadeh, Djawad, additional, Wang, Jun, additional, Demirkan, Ayse, additional, Le Roy, Caroline I., additional, Raygoza Garay, Juan Antonio, additional, Finnicum, Casey T., additional, Liu, Xingrong, additional, Zhernakova, Daria V., additional, Bonder, Marc Jan, additional, Hansen, Tue H., additional, Frost, Fabian, additional, Rühlemann, Malte C., additional, Turpin, Williams, additional, Moon, Jee-Young, additional, Kim, Han-Na, additional, Lüll, Kreete, additional, Barkan, Elad, additional, Shah, Shiraz A., additional, Fornage, Myriam, additional, Szopinska-Tokov, Joanna, additional, Wallen, Zachary D., additional, Borisevich, Dmitrii, additional, Agreus, Lars, additional, Andreasson, Anna, additional, Bang, Corinna, additional, Bedrani, Larbi, additional, Bell, Jordana T., additional, Bisgaard, Hans, additional, Boehnke, Michael, additional, Boomsma, Dorret I., additional, Burk, Robert D., additional, Claringbould, Annique, additional, Croitoru, Kenneth, additional, Davies, Gareth E., additional, van Duijn, Cornelia M., additional, Duijts, Liesbeth, additional, Falony, Gwen, additional, Fu, Jingyuan, additional, van der Graaf, Adriaan, additional, Hansen, Torben, additional, Homuth, Georg, additional, Hughes, David A., additional, Ijzerman, Richard G., additional, Jackson, Matthew A., additional, Jaddoe, Vincent W. V., additional, Joossens, Marie, additional, Jørgensen, Torben, additional, Keszthelyi, Daniel, additional, Knight, Rob, additional, Laakso, Markku, additional, Laudes, Matthias, additional, Launer, Lenore J., additional, Lieb, Wolfgang, additional, Lusis, Aldons J., additional, Masclee, Ad A. M., additional, Moll, Henriette A., additional, Mujagic, Zlatan, additional, Qibin, Qi, additional, Rothschild, Daphna, additional, Shin, Hocheol, additional, Sørensen, Søren J., additional, Steves, Claire J., additional, Thorsen, Jonathan, additional, Timpson, Nicholas J., additional, Tito, Raul Y., additional, Vieira-Silva, Sara, additional, Völker, Uwe, additional, Völzke, Henry, additional, Võsa, Urmo, additional, Wade, Kaitlin H., additional, Walter, Susanna, additional, Watanabe, Kyoko, additional, Weiss, Stefan, additional, Weiss, Frank U., additional, Weissbrod, Omer, additional, Westra, Harm-Jan, additional, Willemsen, Gonneke, additional, Payami, Haydeh, additional, Jonkers, Daisy M. A. E., additional, Arias Vasquez, Alejandro, additional, de Geus, Eco J. C., additional, Meyer, Katie A., additional, Stokholm, Jakob, additional, Segal, Eran, additional, Org, Elin, additional, Wijmenga, Cisca, additional, Kim, Hyung-Lae, additional, Kaplan, Robert C., additional, Spector, Tim D., additional, Uitterlinden, Andre G., additional, Rivadeneira, Fernando, additional, Franke, Andre, additional, Lerch, Markus M., additional, Franke, Lude, additional, Sanna, Serena, additional, D’Amato, Mauro, additional, Pedersen, Oluf, additional, Paterson, Andrew D., additional, Kraaij, Robert, additional, Raes, Jeroen, additional, and Zhernakova, Alexandra, additional

Published
2021
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15. Lack of association between proton pump inhibitor use and brain aging: a cross-sectional study

Author

Ahn, Nayeon, primary, Frenzel, Stefan, additional, Wittfeld, Katharina, additional, Bülow, Robin, additional, Völzke, Henry, additional, Lerch, Markus M., additional, Chenot, Jean-Francois, additional, Schminke, Ulf, additional, Nolde, Michael, additional, Amann, Ute, additional, Meisinger, Christa, additional, Linseisen, Jakob, additional, Baumeister, Sebastian E., additional, Grabe, Hans Jörgen, additional, and Rückert-Eheberg, Ina-Maria, additional

Published
2021
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18. Quality of life and olfactory function after suprasellar craniopharyngioma surgery—a single-center experience comparing transcranial and endoscopic endonasal approaches

Author

Marx, Sascha, primary, Tsavdaridou, Ioanna, additional, Paul, Sebastian, additional, Steveling, Antje, additional, Schirmer, Cornelia, additional, Eördögh, Marton, additional, Nowak, Stephan, additional, Matthes, Marc, additional, El Refaee, Ehab, additional, Fleck, Steffen K., additional, Baldauf, Joerg, additional, Lerch, Markus M., additional, Stahl, Andreas, additional, Hosemann, Werner, additional, and Schroeder, Henry W. S., additional

Published
2020
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19. Helicobacter pylori infection associates with fecal microbiota composition and diversity

Author

Frost, Fabian, primary, Kacprowski, Tim, additional, Rühlemann, Malte, additional, Bang, Corinna, additional, Franke, Andre, additional, Zimmermann, Kathrin, additional, Nauck, Matthias, additional, Völker, Uwe, additional, Völzke, Henry, additional, Biffar, Reiner, additional, Schulz, Christian, additional, Mayerle, Julia, additional, Weiss, Frank U., additional, Homuth, Georg, additional, and Lerch, Markus M., additional

Published
2019
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22. The impact of diabetes mellitus on survival following resection and adjuvant chemotherapy for pancreatic cancer

Author

Kleeff, Jorg, Costello, Eithne, Jackson, Richard, Halloran, Chris, Greenhalf, William, Ghaneh, Paula, Lamb, Richard F, Lerch, Markus M, Mayerle, Julia, Palmer, Daniel, Cox, Trevor, Rawcliffe, Charlotte L, Strobel, Oliver, Buechler, Markus W, Neoptolemos, John P, and Canc, European Study Grp Pancreatic

Subjects
Male, Cancer Research, Epidemiology, medicine.medical_treatment, pancreatic cancer, Comorbidity, Kaplan-Meier Estimate, Gastroenterology, 0302 clinical medicine, Risk Factors, Insulin, Multicenter Studies as Topic, resection, Randomized Controlled Trials as Topic, Aged, 80 and over, Hazard ratio, adjuvant therapy, Middle Aged, Prognosis, Tumor Burden, Treatment Outcome, Oncology, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Pancreatectomy, Female, 030211 gastroenterology & hepatology, Carcinoma, Pancreatic Ductal, medicine.medical_specialty, 03 medical and health sciences, Internal medicine, Diabetes mellitus, Pancreatic cancer, Diabetes Mellitus, medicine, Carcinoma, Humans, Risk factor, Aged, Proportional Hazards Models, Proportional hazards model, business.industry, Overweight, medicine.disease, Surgery, Pancreatic Neoplasms, Clinical Trials, Phase III as Topic, business
Abstract

Background: Diabetes mellitus is frequently observed in pancreatic cancer patients and is both a risk factor and an early manifestation of the disease. Methods: We analysed the prognostic impact of diabetes on the outcome of pancreatic cancer following resection and adjuvant chemotherapy using individual patient data from three European Study Group for Pancreatic Cancer randomised controlled trials. Analyses were carried out to assess the association between clinical characteristics and the presence of preoperative diabetes, as well as the effect of diabetic status on overall survival. Results: In total, 1105 patients were included in the analysis, of whom 257 (23%) had confirmed diabetes and 848 (77%) did not. Median (95% confidence interval (CI)) unadjusted overall survival in non-diabetic patients was 22.3 (20.8–24.1) months compared with 18.8 (16.9–22.1) months for diabetic patients (P=0.24). Diabetic patients were older, had increased weight and more co-morbidities. Following adjustment, multivariable analysis demonstrated that diabetic patients had an increased risk of death (hazard ratio: 1.19 (95% CI 1.01, 1.40), P=0.034). Maximum tumour size of diabetic patients was larger at randomisation (33.6 vs 29.7 mm, P=0.026). Conclusions: Diabetes mellitus was associated with increased tumour size and reduced survival following pancreatic cancer resection and adjuvant chemotherapy.

Published
2016

23. Associations of autozygosity with a broad range of human phenotypes

Author

Clark, David W, primary, Okada, Yukinori, additional, Moore, Kristjan H S, additional, Mason, Dan, additional, Pirastu, Nicola, additional, Gandin, Ilaria, additional, Mattsson, Hannele, additional, Barnes, Catriona L K, additional, Lin, Kuang, additional, Zhao, Jing Hua, additional, Deelen, Patrick, additional, Rohde, Rebecca, additional, Schurmann, Claudia, additional, Guo, Xiuqing, additional, Giulianini, Franco, additional, Zhang, Weihua, additional, Medina-Gomez, Carolina, additional, Karlsson, Robert, additional, Bao, Yanchun, additional, Bartz, Traci M, additional, Baumbach, Clemens, additional, Biino, Ginevra, additional, Bixley, Matthew J, additional, Brumat, Marco, additional, Chai, Jin-Fang, additional, Corre, Tanguy, additional, Cousminer, Diana L, additional, Dekker, Annelot M, additional, Eccles, David A, additional, van Eijk, Kristel R, additional, Fuchsberger, Christian, additional, Gao, He, additional, Germain, Marine, additional, Gordon, Scott D, additional, de Haan, Hugoline G, additional, Harris, Sarah E, additional, Hofer, Edith, additional, Huerta-Chagoya, Alicia, additional, Igartua, Catherine, additional, Jansen, Iris E, additional, Jia, Yucheng, additional, Kacprowski, Tim, additional, Karlsson, Torgny, additional, Kleber, Marcus E, additional, Li, Shengchao Alfred, additional, Li-Gao, Ruifang, additional, Mahajan, Anubha, additional, Matsuda, Koichi, additional, Meidtner, Karina, additional, Meng, Weihua, additional, Montasser, May E, additional, van der Most, Peter J, additional, Munz, Matthias, additional, Nutile, Teresa, additional, Palviainen, Teemu, additional, Prasad, Gauri, additional, Prasad, Rashmi B, additional, Priyanka, Tallapragada Divya Sri, additional, Rizzi, Federica, additional, Salvi, Erika, additional, Sapkota, Bishwa R, additional, Shriner, Daniel, additional, Skotte, Line, additional, Smart, Melissa C, additional, Smith, Albert Vernon, additional, van der Spek, Ashley, additional, Spracklen, Cassandra N, additional, Strawbridge, Rona J, additional, Tajuddin, Salman M, additional, Trompet, Stella, additional, Turman, Constance, additional, Verweij, Niek, additional, Viberti, Clara, additional, Wang, Lihua, additional, Warren, Helen R, additional, Wootton, Robyn E, additional, Yanek, Lisa R, additional, Yao, Jie, additional, Yousri, Noha A, additional, Zhao, Wei, additional, Adeyemo, Adebowale A, additional, Afaq, Saima, additional, Aguilar-Salinas, Carlos Alberto, additional, Akiyama, Masato, additional, Albert, Matthew L, additional, Allison, Matthew A, additional, Alver, Maris, additional, Aung, Tin, additional, Azizi, Fereidoun, additional, Bentley, Amy R, additional, Boeing, Heiner, additional, Boerwinkle, Eric, additional, Borja, Judith B, additional, de Borst, Gert J, additional, Bottinger, Erwin P, additional, Broer, Linda, additional, Campbell, Harry, additional, Chanock, Stephen, additional, Chee, Miao-Li, additional, Chen, Guanjie, additional, Chen, Yii-Der I, additional, Chen, Zhengming, additional, Chiu, Yen-Feng, additional, Cocca, Massimiliano, additional, Collins, Francis S, additional, Concas, Maria Pina, additional, Corley, Janie, additional, Cugliari, Giovanni, additional, van Dam, Rob M, additional, Damulina, Anna, additional, Daneshpour, Maryam S, additional, Day, Felix R, additional, Delgado, Graciela E, additional, Dhana, Klodian, additional, Doney, Alexander S F, additional, Dörr, Marcus, additional, Doumatey, Ayo P, additional, Dzimiri, Nduna, additional, Ebenesersdóttir, S Sunna, additional, Elliott, Joshua, additional, Elliott, Paul, additional, Ewert, Ralf, additional, Felix, Janine F, additional, Fischer, Krista, additional, Freedman, Barry I, additional, Girotto, Giorgia, additional, Goel, Anuj, additional, Gögele, Martin, additional, Goodarzi, Mark O, additional, Graff, Mariaelisa, additional, Granot-Hershkovitz, Einat, additional, Grodstein, Francine, additional, Guarrera, Simonetta, additional, Gudbjartsson, Daniel F, additional, Guity, Kamran, additional, Gunnarsson, Bjarni, additional, Guo, Yu, additional, Hagenaars, Saskia P, additional, Haiman, Christopher A, additional, Halevy, Avner, additional, Harris, Tamara B, additional, Hedayati, Mehdi, additional, van Heel, David A, additional, Hirata, Makoto, additional, Höfer, Imo, additional, Hsiung, Chao Agnes, additional, Huang, Jinyan, additional, Hung, Yi-Jen, additional, Ikram, M Arfan, additional, Jagadeesan, Anuradha, additional, Jousilahti, Pekka, additional, Kamatani, Yoichiro, additional, Kanai, Masahiro, additional, Kerrison, Nicola D, additional, Kessler, Thorsten, additional, Khaw, Kay-Tee, additional, Khor, Chiea Chuen, additional, de Kleijn, Dominique P V, additional, Koh, Woon-Puay, additional, Kolcic, Ivana, additional, Kraft, Peter, additional, Krämer, Bernhard K, additional, Kutalik, Zoltán, additional, Kuusisto, Johanna, additional, Langenberg, Claudia, additional, Launer, Lenore J, additional, Lawlor, Deborah A, additional, Lee, I-Te, additional, Lee, Wen-Jane, additional, Lerch, Markus M, additional, Li, Liming, additional, Liu, Jianjun, additional, Loh, Marie, additional, London, Stephanie J, additional, Loomis, Stephanie, additional, Lu, Yingchang, additional, Luan, Jian’an, additional, Mägi, Reedik, additional, Manichaikul, Ani W, additional, Manunta, Paolo, additional, Másson, Gísli, additional, Matoba, Nana, additional, Mei, Xue W, additional, Meisinger, Christa, additional, Meitinger, Thomas, additional, Mezzavilla, Massimo, additional, Milani, Lili, additional, Millwood, Iona Y, additional, Momozawa, Yukihide, additional, Moore, Amy, additional, Morange, Pierre-Emmanuel, additional, Moreno-Macías, Hortensia, additional, Mori, Trevor A, additional, Morrison, Alanna C, additional, Muka, Taulant, additional, Murakami, Yoshinori, additional, Murray, Alison D, additional, de Mutsert, Renée, additional, Mychaleckyj, Josyf C, additional, Nalls, Mike A, additional, Nauck, Matthias, additional, Neville, Matt J, additional, Nolte, Ilja M, additional, Ong, Ken K, additional, Orozco, Lorena, additional, Padmanabhan, Sandosh, additional, Pálsson, Gunnar, additional, Pankow, James S, additional, Pattaro, Cristian, additional, Pattie, Alison, additional, Polasek, Ozren, additional, Poulter, Neil, additional, Pramstaller, Peter P, additional, Quintana-Murci, Lluis, additional, Räikkönen, Katri, additional, Ralhan, Sarju, additional, Rao, Dabeeru C, additional, van Rheenen, Wouter, additional, Rich, Stephen S, additional, Ridker, Paul M, additional, Rietveld, Cornelius A, additional, Robino, Antonietta, additional, van Rooij, Frank J A, additional, Ruggiero, Daniela, additional, Saba, Yasaman, additional, Sabanayagam, Charumathi, additional, Sabater-Lleal, Maria, additional, Sala, Cinzia Felicita, additional, Salomaa, Veikko, additional, Sandow, Kevin, additional, Schmidt, Helena, additional, Scott, Laura J, additional, Scott, William R, additional, Sedaghati-Khayat, Bahareh, additional, Sennblad, Bengt, additional, van Setten, Jessica, additional, Sever, Peter J, additional, Sheu, Wayne H-H, additional, Shi, Yuan, additional, Shrestha, Smeeta, additional, Shukla, Sharvari Rahul, additional, Sigurdsson, Jon K, additional, Sikka, Timo Tonis, additional, Singh, Jai Rup, additional, Smith, Blair H, additional, Stančáková, Alena, additional, Stanton, Alice, additional, Starr, John M, additional, Stefansdottir, Lilja, additional, Straker, Leon, additional, Sulem, Patrick, additional, Sveinbjornsson, Gardar, additional, Swertz, Morris A, additional, Taylor, Adele M, additional, Taylor, Kent D, additional, Terzikhan, Natalie, additional, Tham, Yih-Chung, additional, Thorleifsson, Gudmar, additional, Thorsteinsdottir, Unnur, additional, Tillander, Annika, additional, Tracy, Russell P, additional, Tusié-Luna, Teresa, additional, Tzoulaki, Ioanna, additional, Vaccargiu, Simona, additional, Vangipurapu, Jagadish, additional, Veldink, Jan H, additional, Vitart, Veronique, additional, Völker, Uwe, additional, Vuoksimaa, Eero, additional, Wakil, Salma M, additional, Waldenberger, Melanie, additional, Wander, Gurpreet S, additional, Wang, Ya Xing, additional, Wareham, Nicholas J, additional, Wild, Sarah, additional, Yajnik, Chittaranjan S, additional, Yuan, Jian-Min, additional, Zeng, Lingyao, additional, Zhang, Liang, additional, Zhou, Jie, additional, Amin, Najaf, additional, Asselbergs, Folkert W, additional, Bakker, Stephan J L, additional, Becker, Diane M, additional, Lehne, Benjamin, additional, Bennett, David A, additional, van den Berg, Leonard H, additional, Berndt, Sonja I, additional, Bharadwaj, Dwaipayan, additional, Bielak, Lawrence F, additional, Bochud, Murielle, additional, Boehnke, Mike, additional, Bouchard, Claude, additional, Bradfield, Jonathan P, additional, Brody, Jennifer A, additional, Campbell, Archie, additional, Carmi, Shai, additional, Caulfield, Mark J, additional, Cesarini, David, additional, Chambers, John C, additional, Chandak, Giriraj Ratan, additional, Cheng, Ching-Yu, additional, Ciullo, Marina, additional, Cornelis, Marilyn, additional, Cusi, Daniele, additional, Smith, George Davey, additional, Deary, Ian J, additional, Dorajoo, Rajkumar, additional, van Duijn, Cornelia M, additional, Ellinghaus, David, additional, Erdmann, Jeanette, additional, Eriksson, Johan G, additional, Evangelou, Evangelos, additional, Evans, Michele K, additional, Faul, Jessica D, additional, Feenstra, Bjarke, additional, Feitosa, Mary, additional, Foisy, Sylvain, additional, Franke, Andre, additional, Friedlander, Yechiel, additional, Gasparini, Paolo, additional, Gieger, Christian, additional, Gonzalez, Clicerio, additional, Goyette, Philippe, additional, Grant, Struan F A, additional, Griffiths, Lyn R, additional, Groop, Leif, additional, Gudnason, Vilmundur, additional, Gyllensten, Ulf, additional, Hakonarson, Hakon, additional, Hamsten, Anders, additional, van der Harst, Pim, additional, Heng, Chew-Kiat, additional, Hicks, Andrew A, additional, Hochner, Hagit, additional, Huikuri, Heikki, additional, Hunt, Steven C, additional, Jaddoe, Vincent W V, additional, De Jager, Philip L, additional, Johannesson, Magnus, additional, Johansson, Åsa, additional, Jonas, Jost B, additional, Jukema, J Wouter, additional, Junttila, Juhani, additional, Kaprio, Jaakko, additional, Kardia, Sharon L. R., additional, Karpe, Fredrik, additional, Kumari, Meena, additional, Laakso, Markku, additional, van der Laan, Sander W, additional, Lahti, Jari, additional, Laudes, Matthias, additional, Lea, Rodney A, additional, Lieb, Wolfgang, additional, Lumley, Thomas, additional, Martin, Nicholas G, additional, März, Winfried, additional, Matullo, Giuseppe, additional, McCarthy, Mark I, additional, Medland, Sarah E, additional, Merriman, Tony R, additional, Metspalu, Andres, additional, Meyer, Brian F, additional, Mohlke, Karen L, additional, Montgomery, Grant W, additional, Mook-Kanamori, Dennis, additional, Munroe, Patricia B, additional, North, Kari E, additional, Nyholt, Dale R, additional, O’connell, Jeffery R, additional, Ober, Carole, additional, Oldehinkel, Albertine J, additional, Palmas, Walter, additional, Palmer, Colin, additional, Pasterkamp, Gerard G, additional, Patin, Etienne, additional, Pennell, Craig E, additional, Perusse, Louis, additional, Peyser, Patricia A, additional, Pirastu, Mario, additional, Polderman, Tinca J. C., additional, Porteous, David J, additional, Posthuma, Danielle, additional, Psaty, Bruce M, additional, Rioux, John D, additional, Rivadeneira, Fernando, additional, Rotimi, Charles, additional, Rotter, Jerome I, additional, Rudan, Igor, additional, Den Ruijter, Hester M, additional, Sanghera, Dharambir K, additional, Sattar, Naveed, additional, Schmidt, Reinhold, additional, Schulze, Matthias B, additional, Schunkert, Heribert, additional, Scott, Robert A, additional, Shuldiner, Alan R, additional, Sim, Xueling, additional, Small, Neil, additional, Smith, Jennifer A, additional, Sotoodehnia, Nona, additional, Tai, E-Shyong, additional, Teumer, Alexander, additional, Timpson, Nicholas J, additional, Toniolo, Daniela, additional, Tregouet, David-Alexandre, additional, Tuomi, Tiinamaija, additional, Vollenweider, Peter, additional, Wang, Carol A, additional, Weir, David R, additional, Whitfield, John B, additional, Wijmenga, Cisca, additional, Wong, Tien-Yin, additional, Wright, John, additional, Yang, Jingyun, additional, Yu, Lei, additional, Zemel, Babette S, additional, Zonderman, Alan B, additional, Perola, Markus, additional, Magnusson, Patrik K. E., additional, Uitterlinden, André G, additional, Kooner, Jaspal S, additional, Chasman, Daniel I, additional, Loos, Ruth J. F., additional, Franceschini, Nora, additional, Franke, Lude, additional, Haley, Chris S, additional, Hayward, Caroline, additional, Walters, Robin G, additional, Perry, John R. B., additional, Esko, Tōnu, additional, Helgason, Agnar, additional, Stefansson, Kari, additional, Joshi, Peter K, additional, Kubo, Michiaki, additional, and Wilson, James F, additional

Published
2019
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24. Copy number variants in lipid metabolism genes are associated with gallstones disease in men

Author

Pérez-Palma, Eduardo, primary, Bustos, Bernabé I., additional, Lal, Dennis, additional, Buch, Stephan, additional, Azocar, Lorena, additional, Toliat, Mohammad Reza, additional, Lieb, Wolfgang, additional, Franke, Andre, additional, Hinz, Sebastian, additional, Burmeister, Greta, additional, von Shönfels, Witigo, additional, Schafmayer, Clemens, additional, Ahnert, Peter, additional, Völzke, Henry, additional, Völker, Uwe, additional, Homuth, Georg, additional, Lerch, Markus M., additional, Puschel, Klaus, additional, Gutiérrez, Rodrigo A., additional, Hampe, Jochen, additional, Nürnberg, Peter, additional, Miquel, Juan Francisco, additional, and De Ferrari, Giancarlo V., additional

Published
2019
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25. Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice

Author

Malla, Sudarshan R., primary, Krueger, Burkhard, additional, Wartmann, Thomas, additional, Sendler, Matthias, additional, Mahajan, Ujjwal M., additional, Weiss, F. Ulrich, additional, Thiel, Franziska G., additional, De Boni, Carina, additional, Gorelick, Fred S., additional, Halangk, Walter, additional, Aghdassi, Ali A., additional, Reinheckel, Thomas, additional, Gukovskaya, Anna S., additional, Lerch, Markus M., additional, and Mayerle, Julia, additional

Published
2019
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26. Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry

Author

Bustos, Bernabé I., primary, Pérez-Palma, Eduardo, additional, Buch, Stephan, additional, Azócar, Lorena, additional, Riveras, Eleodoro, additional, Ugarte, Giorgia D., additional, Toliat, Mohammad, additional, Nürnberg, Peter, additional, Lieb, Wolfgang, additional, Franke, Andre, additional, Hinz, Sebastian, additional, Burmeister, Greta, additional, von Schönfels, Witigo, additional, Schafmayer, Clemens, additional, Völzke, Henry, additional, Völker, Uwe, additional, Homuth, Georg, additional, Lerch, Markus M., additional, Santos, José Luis, additional, Puschel, Klaus, additional, Bambs, Claudia, additional, Roa, Juan Carlos, additional, Gutiérrez, Rodrigo A., additional, Hampe, Jochen, additional, De Ferrari, Giancarlo V., additional, and Miquel, Juan Francisco, additional

Published
2019
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28. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Author

Zillikens, M. Carola, primary, Demissie, Serkalem, additional, Hsu, Yi-Hsiang, additional, Yerges-Armstrong, Laura M., additional, Chou, Wen-Chi, additional, Stolk, Lisette, additional, Livshits, Gregory, additional, Broer, Linda, additional, Johnson, Toby, additional, Koller, Daniel L., additional, Kutalik, Zoltán, additional, Luan, Jian’an, additional, Malkin, Ida, additional, Ried, Janina S., additional, Smith, Albert V., additional, Thorleifsson, Gudmar, additional, Vandenput, Liesbeth, additional, Hua Zhao, Jing, additional, Zhang, Weihua, additional, Aghdassi, Ali, additional, Åkesson, Kristina, additional, Amin, Najaf, additional, Baier, Leslie J., additional, Barroso, Inês, additional, Bennett, David A., additional, Bertram, Lars, additional, Biffar, Rainer, additional, Bochud, Murielle, additional, Boehnke, Michael, additional, Borecki, Ingrid B., additional, Buchman, Aron S., additional, Byberg, Liisa, additional, Campbell, Harry, additional, Campos Obanda, Natalia, additional, Cauley, Jane A., additional, Cawthon, Peggy M., additional, Cederberg, Henna, additional, Chen, Zhao, additional, Cho, Nam H., additional, Jin Choi, Hyung, additional, Claussnitzer, Melina, additional, Collins, Francis, additional, Cummings, Steven R., additional, De Jager, Philip L., additional, Demuth, Ilja, additional, Dhonukshe-Rutten, Rosalie A. M., additional, Diatchenko, Luda, additional, Eiriksdottir, Gudny, additional, Enneman, Anke W., additional, Erdos, Mike, additional, Eriksson, Johan G., additional, Eriksson, Joel, additional, Estrada, Karol, additional, Evans, Daniel S., additional, Feitosa, Mary F., additional, Fu, Mao, additional, Garcia, Melissa, additional, Gieger, Christian, additional, Girke, Thomas, additional, Glazer, Nicole L., additional, Grallert, Harald, additional, Grewal, Jagvir, additional, Han, Bok-Ghee, additional, Hanson, Robert L., additional, Hayward, Caroline, additional, Hofman, Albert, additional, Hoffman, Eric P., additional, Homuth, Georg, additional, Hsueh, Wen-Chi, additional, Hubal, Monica J., additional, Hubbard, Alan, additional, Huffman, Kim M., additional, Husted, Lise B., additional, Illig, Thomas, additional, Ingelsson, Erik, additional, Ittermann, Till, additional, Jansson, John-Olov, additional, Jordan, Joanne M., additional, Jula, Antti, additional, Karlsson, Magnus, additional, Khaw, Kay-Tee, additional, Kilpeläinen, Tuomas O., additional, Klopp, Norman, additional, Kloth, Jacqueline S. L., additional, Koistinen, Heikki A., additional, Kraus, William E., additional, Kritchevsky, Stephen, additional, Kuulasmaa, Teemu, additional, Kuusisto, Johanna, additional, Laakso, Markku, additional, Lahti, Jari, additional, Lang, Thomas, additional, Langdahl, Bente L., additional, Launer, Lenore J., additional, Lee, Jong-Young, additional, Lerch, Markus M., additional, Lewis, Joshua R., additional, Lind, Lars, additional, Lindgren, Cecilia, additional, Liu, Yongmei, additional, Liu, Tian, additional, Liu, Youfang, additional, Ljunggren, Östen, additional, Lorentzon, Mattias, additional, Luben, Robert N., additional, Maixner, William, additional, McGuigan, Fiona E., additional, Medina-Gomez, Carolina, additional, Meitinger, Thomas, additional, Melhus, Håkan, additional, Mellström, Dan, additional, Melov, Simon, additional, Michaëlsson, Karl, additional, Mitchell, Braxton D., additional, Morris, Andrew P., additional, Mosekilde, Leif, additional, Newman, Anne, additional, Nielson, Carrie M., additional, O’Connell, Jeffrey R., additional, Oostra, Ben A., additional, Orwoll, Eric S., additional, Palotie, Aarno, additional, Parker, Stephen C. J., additional, Peacock, Munro, additional, Perola, Markus, additional, Peters, Annette, additional, Polasek, Ozren, additional, Prince, Richard L., additional, Räikkönen, Katri, additional, Ralston, Stuart H., additional, Ripatti, Samuli, additional, Robbins, John A., additional, Rotter, Jerome I., additional, Rudan, Igor, additional, Salomaa, Veikko, additional, Satterfield, Suzanne, additional, Schadt, Eric E., additional, Schipf, Sabine, additional, Scott, Laura, additional, Sehmi, Joban, additional, Shen, Jian, additional, Soo Shin, Chan, additional, Sigurdsson, Gunnar, additional, Smith, Shad, additional, Soranzo, Nicole, additional, Stančáková, Alena, additional, Steinhagen-Thiessen, Elisabeth, additional, Streeten, Elizabeth A., additional, Styrkarsdottir, Unnur, additional, Swart, Karin M. A., additional, Tan, Sian-Tsung, additional, Tarnopolsky, Mark A., additional, Thompson, Patricia, additional, Thomson, Cynthia A., additional, Thorsteinsdottir, Unnur, additional, Tikkanen, Emmi, additional, Tranah, Gregory J., additional, Tuomilehto, Jaakko, additional, van Schoor, Natasja M., additional, Verma, Arjun, additional, Vollenweider, Peter, additional, Völzke, Henry, additional, Wactawski-Wende, Jean, additional, Walker, Mark, additional, Weedon, Michael N., additional, Welch, Ryan, additional, Wichmann, H.-Erich, additional, Widen, Elisabeth, additional, Williams, Frances M. K., additional, Wilson, James F., additional, Wright, Nicole C., additional, Xie, Weijia, additional, Yu, Lei, additional, Zhou, Yanhua, additional, Chambers, John C., additional, Döring, Angela, additional, van Duijn, Cornelia M., additional, Econs, Michael J., additional, Gudnason, Vilmundur, additional, Kooner, Jaspal S., additional, Psaty, Bruce M., additional, Spector, Timothy D., additional, Stefansson, Kari, additional, Rivadeneira, Fernando, additional, Uitterlinden, André G., additional, Wareham, Nicholas J., additional, Ossowski, Vicky, additional, Waterworth, Dawn, additional, Loos, Ruth J. F., additional, Karasik, David, additional, Harris, Tamara B., additional, Ohlsson, Claes, additional, and Kiel, Douglas P., additional

Published
2017
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30. Chronic pancreatitis

Author

Kleeff, Jorg, primary, Whitcomb, David C., additional, Shimosegawa, Tooru, additional, Esposito, Irene, additional, Lerch, Markus M., additional, Gress, Thomas, additional, Mayerle, Julia, additional, Drewes, Asbjørn Mohr, additional, Rebours, Vinciane, additional, Akisik, Fatih, additional, Muñoz, J. Enrique Domínguez, additional, and Neoptolemos, John P., additional

Published
2017
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31. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Author

Zillikens, M. Carola, primary, Demissie, Serkalem, additional, Hsu, Yi-Hsiang, additional, Yerges-Armstrong, Laura M., additional, Chou, Wen-Chi, additional, Stolk, Lisette, additional, Livshits, Gregory, additional, Broer, Linda, additional, Johnson, Toby, additional, Koller, Daniel L., additional, Kutalik, Zoltán, additional, Luan, Jian’an, additional, Malkin, Ida, additional, Ried, Janina S., additional, Smith, Albert V., additional, Thorleifsson, Gudmar, additional, Vandenput, Liesbeth, additional, Hua Zhao, Jing, additional, Zhang, Weihua, additional, Aghdassi, Ali, additional, Åkesson, Kristina, additional, Amin, Najaf, additional, Baier, Leslie J., additional, Barroso, Inês, additional, Bennett, David A., additional, Bertram, Lars, additional, Biffar, Rainer, additional, Bochud, Murielle, additional, Boehnke, Michael, additional, Borecki, Ingrid B., additional, Buchman, Aron S., additional, Byberg, Liisa, additional, Campbell, Harry, additional, Campos Obanda, Natalia, additional, Cauley, Jane A., additional, Cawthon, Peggy M., additional, Cederberg, Henna, additional, Chen, Zhao, additional, Cho, Nam H., additional, Jin Choi, Hyung, additional, Claussnitzer, Melina, additional, Collins, Francis, additional, Cummings, Steven R., additional, De Jager, Philip L., additional, Demuth, Ilja, additional, Dhonukshe-Rutten, Rosalie A. M., additional, Diatchenko, Luda, additional, Eiriksdottir, Gudny, additional, Enneman, Anke W., additional, Erdos, Mike, additional, Eriksson, Johan G., additional, Eriksson, Joel, additional, Estrada, Karol, additional, Evans, Daniel S., additional, Feitosa, Mary F., additional, Fu, Mao, additional, Garcia, Melissa, additional, Gieger, Christian, additional, Girke, Thomas, additional, Glazer, Nicole L., additional, Grallert, Harald, additional, Grewal, Jagvir, additional, Han, Bok-Ghee, additional, Hanson, Robert L., additional, Hayward, Caroline, additional, Hofman, Albert, additional, Hoffman, Eric P., additional, Homuth, Georg, additional, Hsueh, Wen-Chi, additional, Hubal, Monica J., additional, Hubbard, Alan, additional, Huffman, Kim M., additional, Husted, Lise B., additional, Illig, Thomas, additional, Ingelsson, Erik, additional, Ittermann, Till, additional, Jansson, John-Olov, additional, Jordan, Joanne M., additional, Jula, Antti, additional, Karlsson, Magnus, additional, Khaw, Kay-Tee, additional, Kilpeläinen, Tuomas O., additional, Klopp, Norman, additional, Kloth, Jacqueline S. L., additional, Koistinen, Heikki A., additional, Kraus, William E., additional, Kritchevsky, Stephen, additional, Kuulasmaa, Teemu, additional, Kuusisto, Johanna, additional, Laakso, Markku, additional, Lahti, Jari, additional, Lang, Thomas, additional, Langdahl, Bente L., additional, Launer, Lenore J., additional, Lee, Jong-Young, additional, Lerch, Markus M., additional, Lewis, Joshua R., additional, Lind, Lars, additional, Lindgren, Cecilia, additional, Liu, Yongmei, additional, Liu, Tian, additional, Liu, Youfang, additional, Ljunggren, Östen, additional, Lorentzon, Mattias, additional, Luben, Robert N., additional, Maixner, William, additional, McGuigan, Fiona E., additional, Medina-Gomez, Carolina, additional, Meitinger, Thomas, additional, Melhus, Håkan, additional, Mellström, Dan, additional, Melov, Simon, additional, Michaëlsson, Karl, additional, Mitchell, Braxton D., additional, Morris, Andrew P., additional, Mosekilde, Leif, additional, Newman, Anne, additional, Nielson, Carrie M., additional, O’Connell, Jeffrey R., additional, Oostra, Ben A., additional, Orwoll, Eric S., additional, Palotie, Aarno, additional, Parker, Stephen C. J., additional, Peacock, Munro, additional, Perola, Markus, additional, Peters, Annette, additional, Polasek, Ozren, additional, Prince, Richard L., additional, Räikkönen, Katri, additional, Ralston, Stuart H., additional, Ripatti, Samuli, additional, Robbins, John A., additional, Rotter, Jerome I., additional, Rudan, Igor, additional, Salomaa, Veikko, additional, Satterfield, Suzanne, additional, Schadt, Eric E., additional, Schipf, Sabine, additional, Scott, Laura, additional, Sehmi, Joban, additional, Shen, Jian, additional, Soo Shin, Chan, additional, Sigurdsson, Gunnar, additional, Smith, Shad, additional, Soranzo, Nicole, additional, Stančáková, Alena, additional, Steinhagen-Thiessen, Elisabeth, additional, Streeten, Elizabeth A., additional, Styrkarsdottir, Unnur, additional, Swart, Karin M. A., additional, Tan, Sian-Tsung, additional, Tarnopolsky, Mark A., additional, Thompson, Patricia, additional, Thomson, Cynthia A., additional, Thorsteinsdottir, Unnur, additional, Tikkanen, Emmi, additional, Tranah, Gregory J., additional, Tuomilehto, Jaakko, additional, van Schoor, Natasja M., additional, Verma, Arjun, additional, Vollenweider, Peter, additional, Völzke, Henry, additional, Wactawski-Wende, Jean, additional, Walker, Mark, additional, Weedon, Michael N., additional, Welch, Ryan, additional, Wichmann, H.-Erich, additional, Widen, Elisabeth, additional, Williams, Frances M. K., additional, Wilson, James F., additional, Wright, Nicole C., additional, Xie, Weijia, additional, Yu, Lei, additional, Zhou, Yanhua, additional, Chambers, John C., additional, Döring, Angela, additional, van Duijn, Cornelia M., additional, Econs, Michael J., additional, Gudnason, Vilmundur, additional, Kooner, Jaspal S., additional, Psaty, Bruce M., additional, Spector, Timothy D., additional, Stefansson, Kari, additional, Rivadeneira, Fernando, additional, Uitterlinden, André G., additional, Wareham, Nicholas J., additional, Ossowski, Vicky, additional, Waterworth, Dawn, additional, Loos, Ruth J. F., additional, Karasik, David, additional, Harris, Tamara B., additional, Ohlsson, Claes, additional, and Kiel, Douglas P., additional

Published
2017
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32. Schlangenbiss

Author

Bertheau, Sarah, primary, Runge, Sören, additional, Lerch, Markus M., additional, and Simon, Peter, additional

Published
2017
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35. A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis

Author

Heiko, Witt, Miklos Sahin Toth, Olfert, Landt, Jian Min Chen, Thilo, Kahne, Drenth, Joost P. H., Zoltan, Kukor, Edit, Szepessy, Walter, Halangk, Stefan, Dahm, Klaus, Rohde, Hans Ulrich Schulz, Cedric Le Marechal, Nejat, Akar, Ammann, Rudolf W., Kaspar, Truninger, Mario, Bargetzi, Eesh, Bhatia, Carlo, Castellani, Giulia Martina Cavestro, Milos, Cerny, DESTRO-BISOL, Giovanni, Spedini, Gabriella, Hans, Eiberg, Jansen, Jan B. M. J., Monika, Koudova, Eva, Rausova, Milan, Macek, Macek Jr, M., Nuria, Malats, Real, Francisco X., Hans Jurgen Menzel, Pedro, Moral, Roberta, Galavotti, Pier Franco Pignatti, Olga, Rickards, Julius, Spicak, Narcis Octavian Zarnescu, Wolfgang, Bock, Gress, Thomas M., Helmut, Friess, Johann, Ockenga, Hartmut, Schmidt, Roland, Pfutzer, Matthias, Lohr, Peter, Simon, Frank Ulrich Weiss, Lerch, Markus M., Niels, Teich, Volker, Keim, Thomas, Berg, Bertram, Wiedenmann, Werner, Luck, David Alexander Groneberg, Michael, Becker, Thomas, Keil, Andreas, Kage, Jana, Bernardova, Markus, Braun, Claudia, Guldner, Juliane, Halangk, Jonas, Rosendahl, Ulrike, Witt, Matthias, Treiber, Renate, Nickel, Claude, Ferec, Witt, H, SAHIN TOTH, M, Landt, O, Chen, Jm, Kahne, T, Drenth, Jp, Kukor, Z, Szepessy, E, Halangk, W, Dahm, S, Rohde, K, Schulz, Hu, LE MARECHAL, C, Akar, N, Ammann, Rw, Truninger, K, Bargetzi, M, Bhatia, E, Castellani, C, Cavestro, GIULIA MARTINA, Cerny, M, DESTRO BISOL, G, Spedini, G, Eiberg, H, Jansen, Jb, Koudova, M, Rausova, E, MACEK M., Jr, Malats, N, Real, Fx, Menzel, Hj, Moral, P, Galavotti, R, Pignatti, Pf, Rickards, O, Spicak, J, Zarnescu, No, Bock, W, Gress, Tm, Friess, H, Ockenga, J, Schmidt, H, Pfutzer, R, Lohr, M, Simon, P, Weiss, Fu, Lerch, Mm, Teich, N, Keim, V, Berg, T, Wiedenmann, B, Luck, W, Groneberg, Da, Becker, M, Keil, T, Kage, A, Bernardova, J, Braun, M, Guldner, C, Halangk, J, Rosendahl, J, Witt, U, Treiber, M, Nickel, R, and Ferec, C.

Subjects
trypsin inhibitor, Models, Molecular, Enteropeptidase, Pancreatic disease, Membrane transport and intracellular motility [NCMLS 5], arginine, genetic risk, chemistry.chemical_compound, Models, proteinosis, Trypsin, Pancreatic Secretory Trypsin Inhibitor, PRSS1 gene, enteropeptidase, medicine.diagnostic_test, adult, Hydrolysis, cationic trypsinogen, protection, unclassified drug, enzyme activity, female, priority journal, risk factor, CHRONIC PANCREATITIS, protein degradation, Trypsinogen, medicine.drug, medicine.medical_specialty, anionic trypsinogen, Proteolysis, Biology, Article, male, Internal medicine, Genetics, medicine, Matrix-Assisted Laser Desorption-Ionization, Humans, PRSS2, controlled study, human, Molecular gastro-enterology and hepatology [IGMD 2], gene, DNA Primers, Genetic polymorphism, catalysis, Base Sequence, Spectrometry, disease predisposition, Molecular, cationic trypsinogen prss1, glycine, pancreatic secretory trypsin inhibitor spink1, trypsin, trypsinogen, article, chronic pancreatitis, codon, genetic susceptibility, major clinical study, nucleotide sequence, Chronic Disease, Haplotypes, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Mass, medicine.disease, Tripsinogen, Tripsina, Settore BIO/18 - Genetica, Endocrinology, Genetic defects of metabolism [UMCN 5.1], Pancreatitis, chemistry, Genètica
Abstract

Chronic pancreatitis is a common inflammatory disease of the pancreas. Mutations in the genes encoding cationic trypsinogen (PRSS1) and the pancreatic secretory trypsin inhibitor (SPINK1) are associated with chronic pancreatitis. Because increased proteolytic activity owing to mutated PRSS1 enhances the risk for chronic pancreatitis, mutations in the gene encoding anionic trypsinogen (PRSS2) may also predispose to disease. Here we analyzed PRSS2 in individuals with chronic pancreatitis and controls and found, to our surprise, that a variant of codon 191 (G191R) is overrepresented in control subjects: G191R was present in 220/6,459 (3.4%) controls but in only 32/2,466 (1.3%) affected individuals (odds ratio 0.37; P = 1.1 x 10(-8)). Upon activation by enterokinase or trypsin, purified recombinant G191R protein showed a complete loss of trypsin activity owing to the introduction of a new tryptic cleavage site that renders the enzyme hypersensitive to autocatalytic proteolysis. In conclusion, the G191R variant of PRSS2 mitigates intrapancreatic trypsin activity and thereby protects against chronic pancreatitis. The initial experiments were supported by the DFG (Wi 2036/1-1). This work was supported by the Sonnenfeld-Stiftung, Berlin, Germany (to H.W.), the US National Institutes of Health (NIH) (grant DK058088 to M.S.-T.), INSERM (Institut National de la Santé et de la Recherche Médicale) and the Programme Hospitalier de Recherche Clinique (grant PHRC R 08-04 to C.F.)

Published
2006

36. Evaluation of a non-invasive multisensor accelerometer for calculating energy expenditure in ventilated intensive care patients compared to indirect calorimetry and predictive equations

Author

Krüger, Janine, primary, Kraft, Matthias, additional, Gründling, Matthias, additional, Friesecke, Sigrun, additional, Gärtner, Simone, additional, Vogt, Lena J., additional, Schüler, Nicole, additional, Steveling, Antje, additional, Lerch, Markus M., additional, and Aghdassi, Ali A., additional

Published
2016
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37. Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

Author

Leppkes, Moritz, primary, Maueröder, Christian, additional, Hirth, Sebastian, additional, Nowecki, Stefanie, additional, Günther, Claudia, additional, Billmeier, Ulrike, additional, Paulus, Susanne, additional, Biermann, Mona, additional, Munoz, Luis E., additional, Hoffmann, Markus, additional, Wildner, Dane, additional, Croxford, Andrew L., additional, Waisman, Ari, additional, Mowen, Kerri, additional, Jenne, Dieter E., additional, Krenn, Veit, additional, Mayerle, Julia, additional, Lerch, Markus M., additional, Schett, Georg, additional, Wirtz, Stefan, additional, Neurath, Markus F., additional, Herrmann, Martin, additional, and Becker, Christoph, additional

Published
2016
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39. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

Author

Buch, Stephan, primary, Stickel, Felix, additional, Trépo, Eric, additional, Way, Michael, additional, Herrmann, Alexander, additional, Nischalke, Hans Dieter, additional, Brosch, Mario, additional, Rosendahl, Jonas, additional, Berg, Thomas, additional, Ridinger, Monika, additional, Rietschel, Marcella, additional, McQuillin, Andrew, additional, Frank, Josef, additional, Kiefer, Falk, additional, Schreiber, Stefan, additional, Lieb, Wolfgang, additional, Soyka, Michael, additional, Semmo, Nasser, additional, Aigner, Elmar, additional, Datz, Christian, additional, Schmelz, Renate, additional, Brückner, Stefan, additional, Zeissig, Sebastian, additional, Stephan, Anna-Magdalena, additional, Wodarz, Norbert, additional, Devière, Jacques, additional, Clumeck, Nicolas, additional, Sarrazin, Christoph, additional, Lammert, Frank, additional, Gustot, Thierry, additional, Deltenre, Pierre, additional, Völzke, Henry, additional, Lerch, Markus M, additional, Mayerle, Julia, additional, Eyer, Florian, additional, Schafmayer, Clemens, additional, Cichon, Sven, additional, Nöthen, Markus M, additional, Nothnagel, Michael, additional, Ellinghaus, David, additional, Huse, Klaus, additional, Franke, Andre, additional, Zopf, Steffen, additional, Hellerbrand, Claus, additional, Moreno, Christophe, additional, Franchimont, Denis, additional, Morgan, Marsha Y, additional, and Hampe, Jochen, additional

Published
2015
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41. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis

Author

Fjeld, Karianne, primary, Weiss, Frank Ulrich, additional, Lasher, Denise, additional, Rosendahl, Jonas, additional, Chen, Jian-Min, additional, Johansson, Bente B, additional, Kirsten, Holger, additional, Ruffert, Claudia, additional, Masson, Emmanuelle, additional, Steine, Solrun J, additional, Bugert, Peter, additional, Cnop, Miriam, additional, Grützmann, Robert, additional, Mayerle, Julia, additional, Mössner, Joachim, additional, Ringdal, Monika, additional, Schulz, Hans-Ulrich, additional, Sendler, Matthias, additional, Simon, Peter, additional, Sztromwasser, Paweł, additional, Torsvik, Janniche, additional, Scholz, Markus, additional, Tjora, Erling, additional, Férec, Claude, additional, Witt, Heiko, additional, Lerch, Markus M, additional, Njølstad, Pål R, additional, Johansson, Stefan, additional, and Molven, Anders, additional

Published
2015
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43. Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

Author

Grabe, Hans J, primary, Assel, Heinrich, additional, Bahls, Thomas, additional, Dörr, Marcus, additional, Endlich, Karlhans, additional, Endlich, Nicole, additional, Erdmann, Pia, additional, Ewert, Ralf, additional, Felix, Stephan B, additional, Fiene, Beate, additional, Fischer, Tobias, additional, Flessa, Steffen, additional, Friedrich, Nele, additional, Gadebusch-Bondio, Mariacarla, additional, Salazar, Manuela, additional, Hammer, Elke, additional, Haring, Robin, additional, Havemann, Christoph, additional, Hecker, Michael, additional, Hoffmann, Wolfgang, additional, Holtfreter, Birte, additional, Kacprowski, Tim, additional, Klein, Kathleen, additional, Kocher, Thomas, additional, Kock, Holger, additional, Krafczyk, Janina, additional, Kuhn, Jana, additional, Langanke, Martin, additional, Lendeckel, Uwe, additional, Lerch, Markus M, additional, Lieb, Wolfgang, additional, Lorbeer, Roberto, additional, Mayerle, Julia, additional, Meissner, Konrad, additional, zu Schwabedissen, Henriette, additional, Nauck, Matthias, additional, Ott, Konrad, additional, Rathmann, Wolfgang, additional, Rettig, Rainer, additional, Richardt, Claudia, additional, Saljé, Karen, additional, Schminke, Ulf, additional, Schulz, Andrea, additional, Schwab, Matthias, additional, Siegmund, Werner, additional, Stracke, Sylvia, additional, Suhre, Karsten, additional, Ueffing, Marius, additional, Ungerer, Saskia, additional, Völker, Uwe, additional, Völzke, Henry, additional, Wallaschofski, Henri, additional, Werner, Vivian, additional, Zygmunt, Marek T, additional, and Kroemer, Heyo K, additional

Published
2014
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44. Pre-Study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulphate in the prevention of post-ERCP pancreatitis

Author

Fluhr, Gabriele, primary, Mayerle, Julia, additional, Weber, Eckhard, additional, Aghdassi, Ali, additional, Simon, Peter, additional, Gress, Thomas, additional, Seufferlein, Thomas, additional, Mössner, Joachim, additional, Stallmach, Andreas, additional, Rösch, Thomas, additional, Müller, Martina, additional, Siegmund, Britta, additional, Büchner-Steudel, Petra, additional, Zuber-Jerger, Ina, additional, Kantowski, Marcus, additional, Hoffmeister, Albrecht, additional, Rosendahl, Jonas, additional, Linhart, Thomas, additional, Maul, Jochen, additional, Czakó, László, additional, Hegyi, Péter, additional, Kraft, Matthias, additional, Engel, Georg, additional, Kohlmann, Thomas, additional, Glitsch, Anne, additional, Pickartz, Tilman, additional, Budde, Christoph, additional, Nitsche, Claudia, additional, Storck, Kirsten, additional, and Lerch, Markus M, additional

Published
2013
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45. L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial

Author

Kraft, Matthias, primary, Kraft, Kathleen, additional, Gärtner, Simone, additional, Mayerle, Julia, additional, Simon, Peter, additional, Weber, Eckhard, additional, Schütte, Kerstin, additional, Stieler, Jens, additional, Koula-Jenik, Heide, additional, Holzhauer, Peter, additional, Gröber, Uwe, additional, Engel, Georg, additional, Müller, Cornelia, additional, Feng, You-Shan, additional, Aghdassi, Ali, additional, Nitsche, Claudia, additional, Malfertheiner, Peter, additional, Patrzyk, Maciej, additional, Kohlmann, Thomas, additional, and Lerch, Markus M, additional

Published
2012
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46. Drug-Induced Pancreatitis

Author

Nitsche, Claudia, primary, Maertin, Sandrina, additional, Scheiber, Jonas, additional, Ritter, Christoph A., additional, Lerch, Markus M., additional, and Mayerle, Julia, additional

Published
2012
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48. In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

Author

Partecke, Ivo L, primary, Kaeding, André, additional, Sendler, Matthias, additional, Albers, Nele, additional, Kühn, Jens-P, additional, Speerforck, Sven, additional, Roese, Sebastian, additional, Seubert, Florian, additional, Diedrich, Stephan, additional, Kuehn, Sandra, additional, Weiss, Ulrich F, additional, Mayerle, Julia, additional, Lerch, Markus M, additional, Hadlich, Stefan, additional, Hosten, Norbert, additional, Heidecke, Claus-D, additional, Puls, Ralf, additional, and von Bernstorff, Wolfram, additional

Published
2011
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