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A recent approach to restoration of degraded mountain landscapes (e.g. ski slopes) recommend to sow seed mixtures including ‘site-specific’ species, i.e. native germplasm adapted to the prevailing conditions and ecologically compatible with the area of intervention. To better exploit the potential of these species and enhance their spread in revegetation projects, deeper knowledge is needed, however, on the existing variation in their germplasm, particularly for economically useful traits such as seed yield. Snow clover is one of the recommended ‘site-specific’ legumes. This study evaluated 12 populations of snow clover, collected in three valleys of the Rhaetian Alps, Italy, to assess their variation and highlight any promising material. The evaluation encompassed a mountain and a lowland site, to verify the behaviour of the germplasm also in one environment markedly different from that of origin. Differences among valleys were observed for flower colour, growth habit and type, flowering time and susceptibility to mildew, although the overall pattern of phenotypic diversity was similar among valleys. Some effect of the evaluation site on the expression of morphological and seed production traits, and on the overall diversity, was also evident. Furthermore, the lowland site experienced very high plant mortality towards the end of the first growing season. Individual populations proved a valuable source of variation for seed production. Some populations, in particular, were worth of attention for a possible selection of high-seed-yielding snow clover cultivars. An assessment of the mating system suggested a lack of self-tripping or an almost absolute self-incompatibility in snow clover.

Riesz transforms associated to Hermite functions were introduced by S. Thangavelu, who proved that they are bounded operators on L^p(R^d ), 1 < p < ∞ . In this paper we give a different proof that allows us to show that the Lp-norms of these operators are bounded by a constant not depending on the dimension d. Moreover, we define Riesz transforms of higher order and free dimensional estimates of the L^p-bounds of these operators are obtained. In order to prove the mentioned results we give an extension of the Littlewood-Paley theory that we believe of independent interest. Fil: Harboure, Eleonor Ofelia. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Departamento de Matemáticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática Alberto Calderón; Argentina Fil: Rosa, L. de. Universidad de Buenos Aires; Argentina Fil: Segovia Fernandez, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto Argentino de Matemática Alberto Calderón; Argentina Fil: Torrea Hernández, José Luis. Universidad Autónoma de Madrid; España

The aim of the study was to analyze the real cost of single or tandem high-dose chemotherapy (HDC) and peripheral blood progenitor cell autologous transplant (PBPCT) in patients with breast cancer. We analyzed the costs of 40 PBPCT performed in 20 patients. Tandem transplant was planned for each patient. Resources used and direct costs were identified for each patient. The study was carried out using the hospital perspective and monetary values were reported in 1999 Euro. The mean cost of whole procedure for single transplant was 20816.63 Euro, while the mean cost of tandem transplant was 38770.83 Euro. The cost distribution in the two groups was similar: the most expensive phase of procedure was the supportive phase post transplant (about 60% of total cost), with the categories of cost most represented being professional fees (about 28%) and pharmacy (about 35%). Awaiting more convincing trials of the clinical advantage of HDC in breast cancer, our analytical evaluation of transplant costs for different therapeutic options, single or tandem, permits identification of the most expensive categories in order to intervene for cost savings. Bone Marrow Transplantation (2001) 27, 1031–1035.

In this article we give sufficient conditions on a pair of weight (w, v) for some one-sided operators to be bounded from Lp (vp) to Lp (wp). The operators we deal with include the one-sided fractional maximal operator and the one-sided singular integrals. For the first operator, necessary and sufficient conditions are known (see [8, 6]). These conditions usually amount to checking the boundedness of the operator on functions that are powers of the weights and are hard to check. Our conditions are of Ap type and are therefore easy to verify. Similar results for two-sided operators were obtained by C. Perez in [9] and [10].

Using velocity and magnetogram data extracted from the full-disk field of view of MDI during the 1999 Dynamics Program, we have studied the dynamics of small-scale magnetic elements (3–7 Mm in size) over time periods as long as six days while they are readily visible on the solar disk. By exploiting concurrent time series of magnetograms and Doppler images, we have compared the motion of magnetic flux elements with the supergranular velocity field inferred from the correlation tracking of mesogranular motions. Using this new method (which combines the results from correlation tracking of mesogranules with detailed analysis of simultaneous magnetograms), it is now possible to correlate the motions of the velocity field and magnetic flux for long periods of time and at high temporal resolution. This technique can be utilized to examine the long-term evolution of supergranulation and associated magnetic fields, for it can be applied to data that span far longer time durations than has been possible previously. As tests of its efficacy, we are able to use this method to verify many results of earlier investigations. We confirm that magnetic elements travel at approximately 350 m s −1 throughout the duration of their lifetime as they are transported by supergranular outflows. We also find that the positions of the magnetic flux elements coincide with the supergranular network boundaries and adjust as the supergranular network itself evolves over the six days of this data set. Thus we conclude that this new method permits us to study the extended evolution of the supergranular flow field and its advection of magnetic elements. Since small-scale magnetic elements are strongly advected by turbulent convection, their dynamics can give important insight into the properties of the subsurface convection.

Of 17 patients with mild to moderate essential hypertension, 8 showed echocardiographic evidence of left ventricular hypertrophy. Cardiac and renal function evaluated by glomerular filtration rate (GFR) were studied in all patients before and after 20 weeks of quinapril treatment. Systolic pressure decreased from 174.7 +/- 16.7 to 131.7 +/- 7.7 mmHg (p.0001) and diastolic pressure decreased from 101.8 +/- 9.8 to 80 +/- 4.3 mmHg (p.0001). Left ventricular mass index decreased in the eight patients with left ventricular hypertrophy (p.01). Basal values of GFR were lower than normal in 41% of all patients; GFR increased significantly after 20 weeks of treatment (from 96.5 +/- 32.3 to 108.6 +/- 31.12 ml/min, p.01); it decreased in only one patient. Patients reported few adverse effects to quinapril, and no important clinical laboratory abnormality was observed. Quinapril not only lowered arterial pressure, but it had a distinct effect on regression of left ventricular hypertrophy and favorable effects on renal function.

The authors examine the main clinical, cytologic and nosographic aspects of conditions and syndromes associated with SBH on the basis of the literature data (about 40 cases) and 23 personal ones. It is necessary to distinguish between three nosological conditions of SBH: hereditary disease, hereditary asymptomatic, acquired per se asymptomatic. From the clinical viewpoint less a half of all SBH cases are hereditary and present a syndrome based on splenomegaly, periodic hemorrhagic diathesis (due to variable thrombocytopenia), not rarely associated with hepatomegaly and lung or nervous system changes (often eyes are involved). There is also a second SBH hereditary form, vary rare and clinically different from the former, determined by deficiency of plasma-lecitin-cholesterol acyltransferase. The peculiar features of SBH are discussed by means of optical, cytochemical, electron microscopical investigations which point out the polymorphous aspect of these "famished" macrophages. The material stored by SBH is heterogeneous and the enzymatic defect of the most frequent form still remains obscure. The presence of SBH in different haemopathies has an analogous significance as Gaucher's cells found outside Gaucher's disease. It is impossible today to deny the existence of two well-identified SBHS.