4 results on '"Kristina A. Butler"'
Search Results
2. Current update on malignant epithelial ovarian tumors
- Author
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Christine O. Menias, Sherif B. Elsherif, Malak Itani, Priya Bhosale, Kristina A. Butler, Dhakshinamoorthy Ganeshan, and Chandana Lall
- Subjects
Oncology ,medicine.medical_specialty ,endocrine system diseases ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Urology ,Gastroenterology ,Extent of disease ,Magnetic resonance imaging ,Hepatology ,medicine.disease ,female genital diseases and pregnancy complications ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Gynecological malignancy ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,Radiology, Nuclear Medicine and imaging ,Epithelial ovarian cancer ,Ovarian cancer ,business ,Preoperative imaging - Abstract
Epithelial ovarian cancer (EOC) represents the most frequently occurring gynecological malignancy, accounting for more than 70% of ovarian cancer deaths. Preoperative imaging plays an important role in assessing the extent of disease and guides the next step in surgical decision-making and operative planning. In this article, we will review the multimodality imaging features of various subtypes of EOC. We will also discuss the role of imaging in the staging, management, and surveillance of EOC.
- Published
- 2021
3. Borderline epithelial ovarian tumors: what the radiologist should know
- Author
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Kristina A. Butler, Wendaline M. VanBuren, Christine O. Menias, L W Chen, Kristina T. Flicek, Y Lahkman, and Kika M. Dudiak
- Subjects
medicine.medical_specialty ,Urology ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Radiologists ,Humans ,Medicine ,Pseudomyxoma peritonei ,Mucinous carcinoma ,Radiology, Nuclear Medicine and imaging ,Stage (cooking) ,Peritoneal Neoplasms ,Ovarian Neoplasms ,Radiological and Ultrasound Technology ,business.industry ,Gastroenterology ,Clinical course ,Soft tissue ,Hepatology ,Pseudomyxoma Peritonei ,medicine.disease ,Adenocarcinoma, Mucinous ,Serous fluid ,Management implications ,030220 oncology & carcinogenesis ,Female ,Radiology ,business - Abstract
Ovarian borderline tumors are neoplasms of epithelial origin that are typically present in young patients and tend to have a less aggressive clinical course than malignant tumors. Accurate diagnosis and staging of borderline tumors has important prognostic and management implications (like fertility-sparing procedures) for women of child-bearing age. This article will review the sonographic, CT, and MRI features of borderline epithelial ovarian tumors with histopathologic correlation. Borderline tumors have less soft tissue and thinner walls/septations than malignant tumors. Serous borderline tumors more commonly have papillary projections, which can simulate the appearance of a sea anemone. Mucinous borderline tumors often are larger, multi-cystic, and more commonly unilateral. The borderline mucinous tumors may also present with pseudomyxoma peritonei, which can make it difficult to distinguish from malignant mucinous carcinoma. Ultrasound is usually the first-line modality for imaging these tumors with MRI reserved for further characterizing indeterminate cases. CT is best used to stage tumors for both locoregional and distant metastatic disease. Overall, however, the imaging features overlap with both benign and malignant ovarian tumors. Despite this, it is important for the radiologist to be familiar with the imaging appearances of borderline tumors because they can present in younger patients and may benefit from different clinical/surgical management.
- Published
- 2020
4. Outcomes of Concurrent Breast and Gynecologic Risk Reduction Surgery
- Author
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Barbara A. Pockaj, William J. Casey, Nabil Wasif, Paul M. Magtibay, Javier F. Magrina, Kristina A. Butler, Irene T. Ma, Jeffrey L. Cornella, Raman C. Mahabir, Richard Gray, Alanna M. Rebecca, and Katherine S. Hunt
- Subjects
Adult ,medicine.medical_specialty ,Genital Neoplasms, Female ,Mammaplasty ,medicine.medical_treatment ,Breast surgery ,Salpingo-oophorectomy ,Breast Neoplasms ,Hysterectomy ,03 medical and health sciences ,Gynecologic Surgical Procedures ,Postoperative Complications ,0302 clinical medicine ,Breast cancer ,Surgical oncology ,medicine ,Humans ,Genetic Predisposition to Disease ,Mastectomy ,Aged ,Retrospective Studies ,Aged, 80 and over ,030219 obstetrics & reproductive medicine ,business.industry ,General surgery ,Carcinoma, Ductal, Breast ,Middle Aged ,medicine.disease ,Surgery ,Treatment Outcome ,Oncology ,030220 oncology & carcinogenesis ,Female ,Breast reconstruction ,Ovarian cancer ,business ,Carcinoma in Situ - Abstract
Women considering risk reduction surgery after a diagnosis of breast/ovarian cancer and/or inherited cancer gene mutation face difficult decisions. The safety of combined breast and gynecologic surgery has not been well studied; therefore, we evaluated the outcomes for patients who have undergone coordinated multispecialty surgery.We conducted a retrospective review of patients undergoing simultaneous breast and gynecologic surgery for newly or previously diagnosed breast cancer and/or an inherited cancer gene mutation during the same anesthetic at a single institution from 1999 to 2013.Seventy-three patients with a mean age of 50 years (range 27-88) were identified. Most patients had newly diagnosed breast cancer or ductal carcinoma in situ (62 %) and 28 patients (38 %) had an identified BRCA mutation. Almost all gynecologic procedures were for risk reduction or benign gynecologic conditions (97 %). Mastectomy was performed in 39 patients (53 %), the majority of whom (79 %) underwent immediate reconstruction. The most common gynecologic procedure involved bilateral salpingo-oophorectomy, which was performed alone in 18 patients (25 %) and combined with hysterectomy in 40 patients (55 %). A total of 32 patients (44 %) developed postoperative complications, most of which were minor and did not require surgical intervention or hospitalization. Two of the 19 patients who underwent implant reconstruction (11 %; 3 % of the entire cohort) had major infectious complications requiring explantation.Combined breast and gynecologic procedures for a breast cancer diagnosis and/or risk reduction in patients can be accomplished with acceptable morbidity. Concurrent operations, including reconstruction, can be offered to patients without negatively impacting their outcome.
- Published
- 2016
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