22 results on '"K. Kaye"'
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2. Midwives’ perceptions towards the ministry of health guidelines for the provision of immediate postpartum care in rural health facilities in Uganda
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Mariam Namutebi, Gorrette K. Nalwadda, Simon Kasasa, Patience A. Muwanguzi, and Dan K. Kaye
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Obstetrics and Gynecology - Abstract
Background Guidelines for clinical practice have been part of the Ministry of health’s efforts to improve the quality of care for over two decades. Their benefits have been documented in Uganda. However, having practice guidelines may not always result in their use in care provision. We explored the midwives’ perceptions towards the ministry of health guidelines for providing immediate postpartum care. Methods An exploratory descriptive qualitative study was conducted in three districts in Uganda from September 2020 to January 2021. In-depth interviews with 50 midwives from 35 health centers and 2 hospitals in Mpigi, Butambala, and Gomba districts were done. Thematic analysis of data was done. Results Three themes emerged; awareness and use of the guidelines, perceived drivers, and perceived barriers to the provision of immediate postpartum care. The subthemes for theme I included; awareness of the guidelines, variations in the postpartum care practices, variations in preparedness to manage women with complications, and varied access to continuing midwifery education. Fear of complications and litigation were the perceived drivers of guideline use. On the other hand, lack of knowledge, busy maternity units, organization of the care, and the midwives’ perceptions about their clients were the barriers to guideline use. Midwives felt that new guidelines and policies regarding immediate postpartum care should be disseminated widely. Conclusion The midwives felt that the guidelines were good for the prevention of postpartum complications but their knowledge of the guidelines for the provision of immediate postpartum care was suboptimal. They desired on-job training and mentorship to help them bridge the knowledge gaps. Variations in patient assessment, monitoring, and pre-discharge care were acknowledged and said to be due to a poor reading culture and health facility factors like patient-midwife ratios, unit setup, and prioritization of labor.
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- 2023
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3. Readiness of rural health facilities to provide immediate postpartum care in Uganda
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Mariam Namutebi, Gorrette K. Nalwadda, Simon Kasasa, Patience A. Muwanguzi, Cynthia Kuteesa Ndikuno, and Dan K. Kaye
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Health Policy - Abstract
Background Nearly 60% of maternal and 45% of newborn deaths occur within 24 h after delivery. Immediate postpartum monitoring could avert death from preventable causes including postpartum hemorrhage, and eclampsia among mothers, and birth asphyxia, hypothermia, and sepsis for babies. We aimed at assessing facility readiness for the provision of postpartum care within the immediate postpartum period. Methods A cross-sectional study involving 40 health facilities within the greater Mpigi region, Uganda, was done. An adapted health facility assessment tool was employed in data collection. Data were double-entered into Epi Data version 4.2 and analyzed using STATA version 13 and presented using descriptive statistics. Results Facility readiness for the provision of postpartum care was low (median score 24% (IQR: 18.7, 26.7). Availability, and use of up-to-date, policies, guidelines and written clinical protocols for identifying, monitoring, and managing postpartum care were inconsistent across all levels of care. Lack of or non-functional equipment poses challenges for screening, diagnosing, and treating postnatal emergencies. Frequent stock-outs of essential drugs and supplies, particularly, hydralazine, antibiotics, oxygen, and blood products for transfusions were more common at health centers compared to hospitals. Inadequate human resources and sub-optimal supplies inhibit the proper functioning of health facilities and impact the quality of postpartum care. Overall, private not-for-profit health facilities had higher facility readiness scores. Conclusions Our findings suggest sub-optimal rural health facility readiness to assess, monitor, and manage postpartum emergencies to reduce the risk of preventable maternal/newborn morbidity and mortality. Strengthening health system inputs and supply side factors could improve facility capacity to provide quality postpartum care.
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- 2023
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4. Early contraceptive implants removal and its associated factors among women using implants at a National Referral Hospital, Kampala Uganda
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Dan K Kaye, Gerald Ssebatta, and Scovia Nalugo Mbalinda
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medicine.medical_specialty ,Referral ,Reproductive medicine ,Developing country ,Levonorgestrel ,Early implant removal ,Abortion ,Pregnancy ,Contraceptive Agents, Female ,medicine ,Humans ,Uganda ,Referral and Consultation ,Drug Implants ,Obstetrics ,business.industry ,Research ,Implant ,Obstetrics and Gynecology ,Gynecology and obstetrics ,General Medicine ,Hospitals ,Discontinuation ,Cross-Sectional Studies ,Contraception ,Reproductive Medicine ,Family planning ,RG1-991 ,Female ,Public aspects of medicine ,RA1-1270 ,Rural area ,business - Abstract
Background Early discontinuation of implant contraceptive methods and reasons for discontinuation remains a major concern for family planning programs. Early discontinuation is related to higher rates of the overall fertility rate, unwanted pregnancies leading to possibly induced abortion. There is paucity of data on the practice of discontinuation of contraceptives in developing countries. The objective of the study was to determine the magnitude of early implants discontinuation among women receiving implants services in the study area and the factors associated with it. Methods A cross-sectional study was conducted from 2nd January to 3rd March 2020. Data were collected from 207 women who had come to remove implants on socio-demographic characteristics, obstetric history, duration of implant, and reasons for wanting to remove the implant. We computed the proportion of those who removed the implant before 18 months (early discontinuation). To assess the factors associated with early discontinuation, we estimated the prevalence ratios with a generalized linear model of the poisson family with a log link and robust error variance. Results The proportion of early implant discontinuation was 87/207(42%). Factor associated with early implant discontinuation included; experience of side effects (PR = 1.1; 95% CI 1.03–1.24; P = 0.001), not having received pre-insertion counseling about the benefits and side effects of contraceptive implants (PR = 1.5; 95% CI 1.02–1.30; P = 0.019) and staying in rural areas (PR = 1.1; 95% CI 1.03–1.27; P = 0.014). Conclusion Nearly one in every two mothers have early discontinuation of contraceptive implants. Factors associated with early implant removal include; experience of side effects, lack of counseling services, and staying in rural areas. There is a need for intervention to address high prevalence of early contraceptive removal through improving on counselling services about possible side effects.
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- 2021
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5. Impact of surgery on quality of life of Ugandan women with symptomatic pelvic organ prolapse: a prospective cohort study
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Paul Kalyebara Kato, Richard Migisha, Rodgers Tugume, Henry Mark Lugobe, Verena Geissbüehler, Dan K Kaye, and Musa Kayondo
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Quality of life ,medicine.medical_specialty ,genetic structures ,Referral ,Reproductive medicine ,behavioral disciplines and activities ,Urogynecology ,03 medical and health sciences ,0302 clinical medicine ,Personal hygiene ,Surveys and Questionnaires ,medicine ,Humans ,Mbarara ,Uganda ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Pelvic organ ,030219 obstetrics & reproductive medicine ,business.industry ,Research ,Public health ,Obstetrics and Gynecology ,Gynecology and obstetrics ,General Medicine ,humanities ,Pelvic organ prolapse ,Surgery ,Impact ,Reproductive Medicine ,RG1-991 ,Female ,Public aspects of medicine ,RA1-1270 ,business - Abstract
Background Pelvic organ prolapse (POP) is a significant public health issue that negatively affects the Quality of Life (QOL) of women in both low and high-income countries. About 20% of women will undergo surgery for POP over their lifetime. However, there is a paucity of information on the effect of surgery on QOL especially in resource-limited settings. We therefore assessed the QOL among women with symptomatic POP living in rural southwestern Uganda and the impact of surgery on their quality of life. Methods We conducted a prospective cohort study among 120 women with symptomatic POP scheduled for surgery at the urogynecology unit of Mbarara Regional Referral Hospital. The QOL at baseline and at 1 year after surgery in the domains of physical performance, social interaction, emotional state, sexual life, sleep quality, personal hygiene and urinary bladder function was determined using a King’s Quality of Life questionnaire. A paired t-test was used to compare the difference in mean scores at baseline and at 1-year post-surgery. Results Of the 120 participants that were enrolled at baseline, 117(98%) completed the follow-up period of 1 year. The baseline QOL was poor. The domains with the poorest QOL were physical, social, sexual, emotional and sleep quality. The mean QOL scores in all the domains and the overall QOL significantly improved 1 year after surgery (p Conclusions The QOL was poor among women with symptomatic POP and surgery improved the QOL in all the domains of life. We recommend that surgery as an option for treatment of symptomatic POP should be scaled up to improve on the QOL of these women.
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- 2021
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6. Ethical challenges of the healthcare transition to adult antiretroviral therapy (ART) clinics for adolescents and young people with HIV in Uganda
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Derrick Lusota Amooti, Philippa Musoke, Scovia Nalugo Mbalinda, Sabrina Bakeera-Kitaka, Eleanor Namusoke Magongo, and Dan K Kaye
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Adult ,Transition to Adult Care ,Facilitators ,Health (social science) ,Adolescent ,Social Stigma ,education ,Adult ART clinics ,Stigma (botany) ,HIV Infections ,Context (language use) ,Adolescents ,Transitioning HIV care ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Nursing ,030225 pediatrics ,Health care ,Humans ,Uganda ,030212 general & internal medicine ,Child ,Transition experiences ,lcsh:R723-726 ,business.industry ,Health Policy ,digestive, oral, and skin physiology ,Bioethics ,HIV infection ,Focus group ,Issues, ethics and legal aspects ,Philosophy of medicine ,Ethical challenges ,Quality of Life ,Adolescent HIV clinics ,lcsh:Medical philosophy. Medical ethics ,business ,Psychology ,Barriers ,Research Article ,Adolescent health - Abstract
Background Whereas many adolescents and young people with HIV require the transfer of care from paediatric/adolescent clinics to adult ART clinics, this transition is beset with a multitude of factors that have the potential to hinder or facilitate the process, thereby raising ethical challenges of the transition process. Decisions made regarding therapy, such as when and how to transition to adult HIV care, should consider ethical benefits and risks. Understanding and addressing ethical challenges in the healthcare transition could ensure a smooth and successful transition. The purpose of this study was to analyze the ethical challenges of transitioning HIV care for adolescents into adult HIV clinics. Methods Data presented were derived from 191 adolescents attending nine different health facilities in Uganda, who constituted 18 focus group discussions. In the discussions, facilitators and barriers regarding adolescents transitioning to adult HIV clinics were explored. Guided by the Silences Framework for data interpretation, thematic data analysis was used to analyze the data. The principles of bioethics and the four-boxes ethics framework for clinical care (patient autonomy, medical indications, the context of care, and quality of life) were used to analyze the ethical issues surrounding the transition from adolescent to adult HIV care. Results The key emerging ethical issues were: reduced patient autonomy; increased risk of harm from stigma and loss of privacy and confidentiality; unfriendly adult clinics induce disengagement and disruption of the care continuum; patient preference to transition as a cohort, and contextual factors are critical to a successful transition. Conclusion The priority outcomes of the healthcare transition for adolescents should address ethical challenges of the healthcare transition such as loss of autonomy, stigma, loss of privacy, and discontinuity of care to ensure retention in HIV care, facilitate long-term self-care, offer ongoing all-inclusive healthcare, promote adolescent health and wellbeing and foster trust in the healthcare system. Identifying and addressing the ethical issues related to what hinders or facilitates successful transitions with targeted interventions for the transition process may ensure adolescents and young people with HIV infection remain healthy across the healthcare transition.
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- 2021
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7. The Impact of Gendered Stereotypes on Perceptions of Violence: A Commentary
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Kathryn R. Klement, Charlotte Rebecca Pennington, Elizabeth A. Bates, and Linda K. Kaye
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Sexual violence ,Social Psychology ,05 social sciences ,Z261 ,Psychological intervention ,BATES ,050109 social psychology ,Human sexuality ,Mythology ,Gender Studies ,Z416 ,Developmental and Educational Psychology ,Domestic violence ,0501 psychology and cognitive sciences ,Gender role ,Psychology ,Social psychology ,050104 developmental & child psychology ,Theme (narrative) - Abstract
The present commentary explores the impact of gender role stereotypes on perceptions of both intimate partner violence (IPV) and sexual violence. Two papers published in this issue of Sex Roles explored the influence of gender stereotypes on both IPV (Bates et al., 2019) and rape myths (Klement et al., 2019). An overarching theme of these papers is how gender stereotypes may influence incorrect beliefs in how we view and approach interventions to these two types of violence. Reflecting on this convergence, we have come together as authors to consider how influential and damaging these stereotypes can be to victims of both partner violence and sexual violence. Our paper considers the nature of these stereotypes, who is harmed by them considering both gender and sexuality, and also the impact they have in societal and service responses to violence, as well as policy and practice development
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- 2019
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8. 'Internet Addiction': a Conceptual Minefield
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Linda K. Kaye and Francesca C. Ryding
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050103 clinical psychology ,Platforms ,business.product_category ,Internet addiction ,media_common.quotation_subject ,Internet privacy ,030508 substance abuse ,03 medical and health sciences ,Internet access ,IGD ,0501 psychology and cognitive sciences ,Gratifications ,media_common ,business.industry ,Addiction ,05 social sciences ,Psychiatry and Mental health ,Health psychology ,Contexts ,Commentary ,The Internet ,Technological advance ,0305 other medical science ,business ,Psychology ,Social psychology - Abstract
With Internet connectivity and technological advancement increasing dramatically in recent years, "Internet addiction" (IA) is emerging as a global concern. However, the use of the term 'addiction' has been considered controversial, with debate surfacing as to whether IA merits classification as a psychiatric disorder as its own entity, or whether IA occurs in relation to specific online activities through manifestation of other underlying disorders. Additionally, the changing landscape of Internet mobility and the contextual variations Internet access can hold has further implications towards its conceptualisation and measurement. Without official recognition and agreement on the concept of IA, this can lead to difficulties in efficacy of diagnosis and treatment. This paper therefore provides a critical commentary on the numerous issues of the concept of "Internet addiction", with implications for the efficacy of its measurement and diagnosticity.
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- 2017
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9. Ein erweitertes Facelift-Behandlungskonzept
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K. Kaye
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Gynecology ,medicine.medical_specialty ,business.industry ,Head and neck surgery ,Medicine ,Surgery ,business - Abstract
Chirurgische Facelift-Techniken haben seit mehr als 20 Jahren ihren festen Platz in modernen Gesichtsverjungungskonzepten. Vielfaltige Techniken sind beschrieben worden. Die Tendenz der letzten zehn Jahre geht zu weniger invasiven Eingriffen und naturlichen Resultaten, die ein verjungtes, kein uberstrafftes Gesichtsbild vermitteln. Essenzieller Teil einer Gesichtsverjungung ist die Verjungung bzw. Erneuerung des Hautbildes, welches entscheidend zum Gesamteindruck beitragt. Die reine Repositionierung der Gesichtsvolumina und das Straffen einer gealterten Haut konnen keine umfassende und uberzeugende Verjungung erreichen. Fachubergreifende Kombinationstechniken dienen zur Erweiterung der Indikation des Facelifts und zur Verbesserung des asthetischen Outcomes. Ziel dieses Artikels ist es, Moglichkeiten und Grenzen von zeitgleich mit einer Gesichtsstraffung durchzufuhrenden Hautverjungungstechniken anhand des adjuvanten Einsatzes verschiedener Peelingtechniken und des autologen Fetttransfers im Rahmen unseres P.A.V.E.(„peeling assisted volume enhancing“)-Lift-Konzepts sowie die Effizienz und Sicherheit eines solchermasen erweiterten Behandlungsansatzes aufzuzeigen.
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- 2013
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10. Improving the quality of obstetric care for women with obstructed labour in the national referral hospital in Uganda: lessons learnt from criteria based audit
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Paul Kiondo, Dan K Kaye, Judith Ajeani, and Herbert Kayiga
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Adult ,medicine.medical_specialty ,Quality management ,Adolescent ,Referral ,Attitude of Health Personnel ,Vital signs ,Reproductive medicine ,Audit ,Health administration ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Hospital Administration ,Pregnancy ,Quality of obstetric care ,Obstetrics and Gynaecology ,Health care ,Humans ,Medicine ,Uganda ,Prospective Studies ,030212 general & internal medicine ,Quality improvement ,Equipment and Supplies, Hospital ,Qualitative Research ,Obstructed labour ,Monitoring, Physiologic ,Medical Audit ,030219 obstetrics & reproductive medicine ,Criteria-based audit ,business.industry ,Obstetrics and Gynecology ,Delivery, Obstetric ,medicine.disease ,Dystocia ,Hospitals ,Anti-Bacterial Agents ,Blood Grouping and Crossmatching ,Practice Guidelines as Topic ,Emergency medicine ,Fluid Therapy ,Administration, Intravenous ,Female ,Urinary Catheterization ,business ,Research Article - Abstract
Background Obstructed labour remains a major cause of maternal morbidity and mortality whose complications can be reduced with improved quality of obstetric care. The objective was to assess whether criteria-based audit improves quality of obstetric care provided to women with obstructed labour in Mulago hospital, Uganda. Methods Using criteria-based audit, management of obstructed labour was analyzed prospectively in two audits. Six standards of care were compared. An initial audit of 180 patients was conducted in September/October 2013. The Audit results were shared with key stakeholders. Gaps in patient management were identified and recommendations for improving obstetric care initiated. Six standards of care (intravenous fluids, intravenous antibiotics, monitoring of maternal vital signs, bladder catheterization, delivery within two hours, and blood grouping and cross matching) were implemented. A re-audit of 180 patients with obstructed labour was conducted four months later to evaluate the impact of these recommendations. The results of the two audits were compared. In-depth interviews and focus group discussions were conducted among healthcare providers to identify factors that could have influenced the audit results. Results There was improvement in two standards of care (intravenous fluids and intravenous antibiotic administration) 58.9 % vs. 86.1 %; p
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- 2016
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11. Maternal near misses from two referral hospitals in Uganda: a prospective cohort study on incidence, determinants and prognostic factors
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Dan K Kaye, Othman Kakaire, Nelson Kakande, Scovia Nalugo Mbalinda, Sarah Nakubulwa, Michael O Osinde, Annettee Nakimuli, and Rose C. Nabirye
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Adult ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Near Miss, Healthcare ,Gravidity ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Pre-Eclampsia ,Uterine Rupture ,Pregnancy ,Risk Factors ,Obstetrics and Gynaecology ,Maternal near miss ,medicine ,Humans ,Childbirth ,Uganda ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Referral and Consultation ,030219 obstetrics & reproductive medicine ,Eclampsia ,Obstructed labour ,business.industry ,Incidence ,Postpartum Hemorrhage ,Obstetrics and Gynecology ,medicine.disease ,Obstetric Labor Complications ,Obstetric labor complication ,Hospitalization ,Pregnancy Complications ,Maternal Mortality ,Maternal Death ,Educational Status ,Female ,Maternal death ,business ,Research Article - Abstract
Background Maternal near misses occur more often than maternal deaths and could enable more comprehensive analysis of risk factors, short-term outcomes and prognostic factors of complications during pregnancy and childbirth. The study determined the incidence, determinants and prognostic factors of severe maternal outcomes (near miss or maternal death) in two referral hospitals in Uganda. Methods A prospective cohort study was conducted between March 1, 2013 and February 28, 2014, where cases of severe pregnancy and childbirth complications were included. The clinical conditions included abortion-related complications, obstetric haemorrhage, hypertensive disorders, obstructed labour, infection and pregnancy-specific complications such as febrile illness, anemia and premature rupture of membranes. Near miss cases were defined according to the WHO criteria. Multivariate logistic regression analysis was conducted to identify prognostic factors for severe maternal outcomes. Results Of 3100 women with severe obstetric complications, 130 (4.2 %) were maternal deaths and 695 (22.7 %) were near miss cases. Severe pre-eclampsia was the commonest morbidity (incidence ratio (IR) 7.0 %, case-fatality rate (CFR) 2.3 %), followed by postpartum haemorrhage (IR 6.7 %, CFR 7.2 %). Uterine rupture (IR 5.5 %) caused the highest CFR (17.9 %), followed by eclampsia (IR 0.4 %, CFR 17.8 %). The three groups (maternal deaths, near misses and non-life-threatening obstetric complications) differed significantly regarding gravidity and education level. The commonest diagnostic criteria for maternal near miss were admission to the high dependency unit (HDU) or to the intensive care unit (ICU). Thrombocytopenia, circulatory collapse, referral to a more specialized unit, intubation unrelated to anaesthesia, and cardiopulmonary resuscitation were predictive of maternal death (p
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- 2016
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12. Incidence and determinants of neonatal morbidity after elective caesarean section at the national referral hospital in Kampala, Uganda
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Annettee Nakimuli, Dan K Kaye, Othman Kakaire, Rose C. Nabirye, Scovia Nalugo Mbalinda, Nelson Kakande, Sarah Nakubulwa, and Michael O Osinde
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Adult ,Male ,medicine.medical_specialty ,Pediatrics ,Neonatal intensive care unit ,Adolescent ,medicine.medical_treatment ,Birth weight ,Gestational Age ,Hospitals, General ,Infant, Newborn, Diseases ,General Biochemistry, Genetics and Molecular Biology ,Young Adult ,Humans ,Medicine ,Uganda ,Caesarean section ,Prospective cohort study ,Medicine(all) ,Pregnancy ,Biochemistry, Genetics and Molecular Biology(all) ,Cesarean Section ,business.industry ,Obstetrics ,Incidence ,Infant, Newborn ,Gestational age ,General Medicine ,medicine.disease ,Elective Surgical Procedures ,Gestation ,Female ,business ,Elective Surgical Procedure ,Research Article - Abstract
Background Elective caesarean sections (ECS) have been implicated in increased risk of adverse neonatal outcomes. The primary objective was to assess the incidence and determinants of neonatal morbidity after elective caesarean section deliveries. The secondary objective was to describe the maternal morbidity associated with elective caesarean section. Methods This was a prospective cohort study of women admitted for ECS, as well as their newborns, conducted at Mulago hospital from March 1, 2013 to February 28, 2014. These were followed from the time of the operation until 6 weeks after hospitalization following the caesarean delivery. Data was collected using an interviewer-administered questionnaire and review of medical records for demographic characteristics, obstetric history, current pregnancy complications and pregnancy outcomes up to hospital discharge. Study outcomes were maternal and neonatal morbidity. The data was analyzed using Stata version 12. Results There were 25,846 deliveries during the study period, of which 20,083 (77.7 %) were vaginal deliveries or assisted deliveries, and 5763 (22.3 %) were caesarean sections. Of the caesarean sections, 920 (15.9 %) were ECS. The commonest maternal morbidity was hemorrhage (17.2 %). A birth weight less than 2500 g (aRR 11.0 [95 % CI 8.1–17.2]) or more than 4000 g (aRR 12.2 [95 % CI 10.6–23.2]), delivery at gestation age less than or equal to 38 weeks (aRR 1.62 [95 % 1.20–2.10]), multigravidity (aRR 1.70 [95 % CI 1.20–2.90]) and using general anaesthesia (aRR 2.43 [95 % CI 1.20–5.90]) were associated with risk of neonatal morbidity. The commonest neonatal morbidity is respiratory distress especially if delivery occurs at a gestation age of 37 weeks or lower, if the birth weight is less than 2500 g or more than 4000 g, and if general anesthesia is used. Conclusion Our study shows that at Mulago Hospital, ECS is associated with significant neonatal and maternal morbidity. We recommend that elective caesarean sections be performed after 39 weeks of gestation, and preferably avoid using general anaesthesia.
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- 2015
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13. Still births, neonatal deaths and neonatal near miss cases attributable to severe obstetric complications: a prospective cohort study in two referral hospitals in Uganda
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Nelson Kakande, Sarah Nakubulwa, Rose C. Nabirye, Dan K Kaye, Othman Kakaire, Scovia Nalugo Mbalinda, Michael O Osinde, and Annettee Nakimuli
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Pediatrics ,medicine.medical_specialty ,Neonatal intensive care unit ,HELLP syndrome ,Perinatal Death ,Birth weight ,Pregnancy ,Risk Factors ,Infant Mortality ,Humans ,Medicine ,Childbirth ,Uganda ,Prospective Studies ,Pediatrics, Perinatology, and Child Health ,Obstructed labour ,business.industry ,Obstetrics ,Infant, Newborn ,Infant ,Stillbirth ,medicine.disease ,Infant mortality ,Pregnancy Complications ,Socioeconomic Factors ,Pediatrics, Perinatology and Child Health ,Female ,business ,Premature rupture of membranes ,Research Article - Abstract
Background Neonatal near miss cases occur more often than neonatal deaths and could enable a more comprehensive analysis of risk factors, short-term outcomes and prognostic factors in neonates born to mothers with severe obstetric complications. The objective was to assess the incidence, presentation and perinatal outcomes of severe obstetric morbidity in two referral hospitals in Central Uganda. Methods A prospective cohort study was conducted between March 1, 2013 and February 28, 2014, in which all newborns from cases of severe pregnancy and childbirth complications were eligible for inclusion. The obstetric conditions included obstetric haemorrhage, hypertensive disorders, obstructed labour, chorioamnionitis and pregnancy-specific complications such as malaria, anemia and premature rupture of membranes. Still births, neonatal deaths and neonatal near miss cases (defined using criteria that employed clinical features, presence of organ-system dysfunction and management provided to the newborns were compiled). Stratified and multivariate logistic regression analysis was conducted to identify risk factors for perinatal death. Results Of the 3100 mothers, 192 (6.2%) had abortion complications. Of the remainder, there were 2142 (73.1%) deliveries, from whom the fetal outcomes were 257 (12.0%) still births, 369 (17.2%) neonatal deaths, 786 (36.7%) neonatal near misses and 730 (34.1%) were newborns with no or minimal life threatening complications. Of the 235 babies admitted to the neonatal intensive care unit (NICU), the main reasons for admission were prematurity for 64 (26.8%), birth asphyxia for 59 (23.7%), and grunting respiration for 26 (11.1%). Of the 235 babies, 38 (16.2%) died in the neonatal period, and of these, 16 died in the first 24 hours after admission. Ruptured uterus caused the highest case-specific mortality of 76.8%, and led to 16.9% of all newborn deaths. Across the four groups, there were significant differences in mean birth weight, p = 0.003. Conclusions Antepartum hemorrhage, ruptured uterus, severe preeclampsia, eclampsia, and the syndrome of Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP syndrome), led to statistically significant attributable risk of newborn deaths (still birth or neonatal deaths). Development of severe maternal outcomes, the mothers having been referred, and gravidity of 5 or more were significantly associated with newborn deaths.
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- 2015
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14. Does knowledge of danger signs of pregnancy predict birth preparedness? A critique of the evidence from women admitted with pregnancy complications
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Annettee Nakimuli, Dan K Kaye, Othman Kakaire, Scovia Nalugo Mbalinda, Nelson Kakande, and Michael O Osinde
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Adult ,Birth preparedness ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Population ,Psychological intervention ,Prenatal care ,Maternal near miss ,Young Adult ,Pregnancy ,Surveys and Questionnaires ,Humans ,Medicine ,Childbirth ,Uganda ,education ,education.field_of_study ,business.industry ,Research ,Health Policy ,Public health ,Health services research ,Prenatal Care ,Delivery, Obstetric ,medicine.disease ,Complication readiness ,Hospitalization ,Pregnancy Complications ,Logistic Models ,Female ,Knowledge about danger signs ,Medical emergency ,business - Abstract
Background Improved knowledge of obstetric danger signs, birth preparedness practices, and readiness for emergency complications are among the strategies aimed at both enhancing utilization of maternal health services and increasing access to skilled care during childbirth, particularly for women with obstetric complications. It is unclear whether knowledge of danger signs translates into improved birth preparedness and complication readiness. The objective was to assess the association between knowledge of danger signs and birth preparedness among women admitted with pregnancy complications. Methods The study included 810 women admitted in the antepartum period to Mulago hospital, Uganda. Data was collected on socio-demographic characteristics, reproductive history, pregnancy complications, knowledge of danger signs, and birth preparedness/complication readiness (BPCR). Logistic regression analyses were conducted to explore the relationship between knowledge of danger signs and birth preparedness. Results Only about 1 in 3 women were able to mention at least three of the five basic components of BPCR, and could be regarded as ‘knowledgeable on BPCR’. One in every 4 women could not mention any of the five components. Women with history of obstetric problems during the previous pregnancy were more likely to be knowledgeable on danger signs when compared to those who had no complications in prior pregnancy. Women who were knowledgeable on danger signs were four times more likely to be knowledgeable on BPCR as compared to those who were not knowledgeable. Conclusions Though awareness about danger signs was low, knowledge of danger signs was associated with knowledge of birth preparedness. More emphasis should be given to emergency/complication readiness during antenatal care sessions. There is a need to strengthen existing policy interventions to address birth preparedness and complication readiness for obstetric emergencies.
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- 2014
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15. Lived experiences of women who developed uterine rupture following severe obstructed labor in Mulago hospital, Uganda
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Annettee Nakimuli, Michael O Osinde, Dan K Kaye, Othman Kakaire, Nelson Kakande, and Scovia Nalugo Mbalinda
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Adult ,medicine.medical_specialty ,Population ,Health Services Accessibility ,Quality of life (healthcare) ,Uterine Rupture ,Pregnancy ,Obstetrics and Gynaecology ,Health care ,Humans ,Medicine ,Childbirth ,Uganda ,Survivors ,education ,Intensive care medicine ,education.field_of_study ,business.industry ,Obstetrics ,Research ,Public health ,Obstetrics and Gynecology ,medicine.disease ,Hospitals ,Obstetric Labor Complications ,Obstetric labor complication ,Uterine rupture ,Maternal Mortality ,Reproductive Medicine ,Quality of Life ,Female ,business ,Delivery of Health Care ,Psychosocial - Abstract
Background Maternal mortality is a major public health challenge in Uganda. Whereas uterine rupture remains a major cause of maternal morbidity and mortality, there is limited research into what happens to women who survive such severe obstetric complications. Understanding their experiences might delineate strategies to support survivors. Methods This qualitative study used a phenomenological approach to explore lived experiences of women who developed uterine rupture following obstructed labor. In-depth interviews initially conducted during their hospitalization were repeated 3–6 months after the childbirth event to explore their health and meanings they attached to the traumatic events and their outcomes. Data were analyzed using thematic analysis. Results The resultant themes included barriers to access healthcare, multiple “losses” and enduring physical, psychosocial and economic consequences. Many women who develop uterine rupture fail to access critical care needed due to failure to recognise danger signs of obstructed labor, late decision making for accessing care, geographical barriers to health facilities, late or failure to diagnose obstructed labor at health facilities, and failure to promptly perform caesarean section. Secondly, the sequel of uterine rupture includes several losses (loss of lives, loss of fertility, loss of body image, poor quality of life and disrupted marital relationships). Thirdly, uterine rupture has grim economic consequences for the survivors (with financial loss and loss of income during and after the calamitous events). Conclusion Uterine rupture is associated with poor quality of care due to factors that operate at personal, household, family, community and society levels, and results in dire physical, psychosocial and financial consequences for survivors. There is need to improve access to and provision of emergency obstetric care in order to prevent uterine rupture consequent to obstructed labor. There is also critical need to provide counselling and support to survivors to enable them cope with physical, social, psychological and economic consequences.
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- 2014
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16. Reduced overflow of BDNF from the brain is linked with suicide risk in depressive illness
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Elodie Hotchkin, David Barton, Murray D. Esler, Gavin Lambert, Elisabeth Lambert, Dan K. Kaye, James Anderson, Tye Dawood, and Deepak Haikerwal
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Adult ,Male ,Risk ,medicine.medical_specialty ,Injury control ,MEDLINE ,Poison control ,Suicide prevention ,Occupational safety and health ,Cellular and Molecular Neuroscience ,Injury prevention ,medicine ,Humans ,Suicide Risk ,Psychiatry ,Molecular Biology ,Depression ,Brain-Derived Neurotrophic Factor ,Brain ,Human factors and ergonomics ,Middle Aged ,Suicide ,Psychiatry and Mental health ,Female ,Psychology ,Clinical psychology - Published
- 2007
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17. Doctoral training in Uganda: evaluation of mentoring best practices at Makerere university college of health sciences
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Damalie Nakanjako, Elialilia S. Okello, Harriet Mayanja-Kizza, Achilles Katamba, Nelson K. Sewankambo, Dan K Kaye, and Moses R. Kamya
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Program evaluation ,Low and middle income countries ,Best practice ,Capacity building ,Supervision ,Education ,Schools, Health Occupations ,Mentorship ,Health care ,ComputingMilieux_COMPUTERSANDEDUCATION ,Medicine ,Uganda ,Education, Graduate ,Qualitative Research ,ComputingMilieux_MISCELLANEOUS ,Medicine(all) ,Medical education ,ComputingMilieux_THECOMPUTINGPROFESSION ,business.industry ,Mentors ,General Medicine ,ComputingMilieux_GENERAL ,Doctoral training ,business ,Research Article ,Program Evaluation ,Qualitative research - Abstract
Background Good mentoring is a key variable for determining success in completing a doctoral program. We identified prevailing mentoring practices among doctoral students and their mentors, identified common challenges facing doctoral training, and proposed some solutions to enhance the quality of the doctoral training experience for both candidates and mentors at Makerere University College of Health Sciences (MakCHS). Methods This cross-sectional qualitative evaluation was part of the monitoring and evaluation program for doctoral training. All doctoral students and their mentors were invited for a half-day workshop through the MakCHS mailing list. Prevailing doctoral supervision and mentoring guidelines were summarised in a one-hour presentation. Participants were split into two homogenous students’ (mentees’) and mentors’ groups to discuss specific issues using a focus group discussion (FGD) guide, that highlighted four main themes in regard to the doctoral training experience; what was going well, what was not going well, proposed solutions to current challenges and perceived high priority areas for improvement. The two groups came together again and the note-takers from each group presented their data and discussions were recorded by a note-taker. Results Twelve out of 36 invited mentors (33%) and 22 out of 40 invited mentees (55%) attended the workshop. Mentors and mentees noted increasing numbers of doctoral students and mentors, which provided opportunities for peer mentorship. Delays in procurement and research regulatory processes subsequently delayed students’ projects. Similarly, mentees mentioned challenges of limited; 1) infrastructure and mentors to support basic science research projects, 2) physical office space for doctoral students and their mentors, 3) skills in budgeting and finance management and 4) communication skills including conflict resolution. As solutions, the team proposed skills’ training, induction courses for doctoral students-mentor teams, and a Frequently Asked Questions’ document, to better inform mentors’, mentees’ expectations and experiences. Conclusion Systemic and infrastructural limitations affect the quality of the doctoral training experience at MaKCHS. Clinical and biomedical research infrastructure, in addition to training in research regulatory processes, procurement and finance management, communication skills and information technology, were highlighted as high priority areas for strategic interventions to improve mentoring within doctoral training of clinician scientists.
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- 2014
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18. Community awareness about risk factors, presentation and prevention and obstetric fistula in Nabitovu village, Iganga district, Uganda
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Scovia Nalugo Mbalinda, Nassar Kasamba, and Dan K Kaye
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Adult ,Male ,Rural Population ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Adolescent ,Fistula ,Reproductive medicine ,Vesicovaginal fistula ,Young Adult ,Pregnancy ,Risk Factors ,Obstetrics and Gynaecology ,medicine ,Humans ,Uganda ,Qualitative Research ,Obstructed labour ,Vesicovaginal Fistula ,business.industry ,Obstetrics ,Rectovaginal Fistula ,Obstetrics and Gynecology ,Focus Groups ,Middle Aged ,medicine.disease ,Focus group ,Obstetric Labor Complications ,Obstetric labor complication ,Family planning ,Rectovaginal fistula ,Family medicine ,Female ,business ,Research Article - Abstract
Background Obstetric fistula is a worldwide problem that is devastating for women in developing countries. The cardinal cause of obstetric fistula is prolonged obstructed labour and delay in seeking emergency obstetric care. Awareness about obstetric fistula is still low in developing countries. The objective was to assess the awareness about risk factors of obstetric fistulae in rural communities of Nabitovu village, Iganga district, Eastern Uganda. Methods A qualitative study using focus group discussion for males and females aged 18-49 years, to explore and gain deeper understanding of their awareness of existence, causes, clinical presentation and preventive measures for obstetric fistula. Data was analyzed by thematic analysis. Results The majority of the women and a few men were aware about obstetric fistula, though many had misconceptions regarding its causes, clinical presentation and prevention. Some wrongly attributed fistula to misuse of family planning, having sex during the menstruation period, curses by relatives, sexually transmitted infections, rape and gender-based violence. However, others attributed the fistula to delays to access medical care, induced abortions, conception at an early age, utilization of traditional birth attendants at delivery, and some complications that could occur during surgical operations for difficult deliveries. Conclusion Most of the community members interviewed were aware of the risk factors of obstetric fistula. Some respondents, predominantly men, had misconceptions/myths about risk factors of obstetric fistula as being caused by having sex during menstrual periods, poor usage of family planning, being a curse.
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- 2013
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19. A community mobilisation intervention to prevent violence against women and reduce HIV/AIDS risk in Kampala, Uganda (the SASA! Study): study protocol for a cluster randomised controlled trial
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Charlotte Watts, Tina Musuya, Karen Devries, Ligia Kiss, Dan K Kaye, Elizabeth Starmann, Leilani Francisco, Janet Nakuti, Nambusi Kyegombe, Tanya Abramsky, and Lori Michau
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Adult ,Male ,Sexual partner ,Domestic Violence ,medicine.medical_specialty ,Adolescent ,Population ,Psychological intervention ,Community randomised trial ,Medicine (miscellaneous) ,Poison control ,HIV Infections ,Models, Psychological ,Community Networks ,Young Adult ,Study Protocol ,Acquired immunodeficiency syndrome (AIDS) ,Risk Factors ,Intervention (counseling) ,Cluster Analysis ,Humans ,Medicine ,Uganda ,Pharmacology (medical) ,Cluster randomised controlled trial ,Psychiatry ,education ,SASA ,lcsh:R5-920 ,Acquired Immunodeficiency Syndrome ,education.field_of_study ,business.industry ,Battered Women ,Community mobilisation ,Behaviour change ,Gender ,Middle Aged ,medicine.disease ,Violence against women ,Intimate partner violence ,Epidemiologic Research Design ,Family medicine ,HIV/AIDS ,Domestic violence ,Female ,lcsh:Medicine (General) ,business - Abstract
Background Gender based violence, including violence by an intimate partner, is a major global human rights and public health problem, with important connections with HIV risk. Indeed, the elimination of sexual and gender based violence is a core pillar of HIV prevention for UNAIDS. Integrated strategies to address the gender norms, relations and inequities that underlie both violence against women and HIV/AIDS are needed. However there is limited evidence about the potential impact of different intervention models. This protocol describes the SASA! Study: an evaluation of a community mobilisation intervention to prevent violence against women and reduce HIV/AIDS risk in Kampala, Uganda. Methods/Design The SASA! Study is a pair-matched cluster randomised controlled trial being conducted in eight communities in Kampala. It is designed to assess the community-level impact of the SASA! intervention on the following six primary outcomes: attitudes towards the acceptability of violence against women and the acceptability of a woman refusing sex (among male and female community members); past year experience of physical intimate partner violence and sexual intimate partner violence (among females); community responses to women experiencing violence (among women reporting past year physical/sexual partner violence); and past year concurrency of sexual partners (among males). 1583 women and men (aged 18–49 years) were surveyed in intervention and control communities prior to intervention implementation in 2007/8. A follow-up cross-sectional survey of community members will take place in 2012. The primary analysis will be an adjusted cluster-level intention to treat analysis, comparing outcomes in intervention and control communities at follow-up. Complementary monitoring and evaluation and qualitative research will be used to explore and describe the process of intervention implementation and the pathways through which change is achieved. Discussion This is one of few cluster randomised trials globally to assess the impact of a gender-focused community mobilisation intervention. The multi-disciplinary research approach will enable us to address questions of intervention impact and mechanisms of action, as well as its feasibility, acceptability and transferability to other contexts. The results will be of importance to researchers, policy makers and those working on the front line to prevent violence against women and HIV. Trial registration ClinicalTrials.Gov NCT00790959
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- 2012
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20. Intimate partner violence among women with HIV infection in rural Uganda: critical implications for policy and practice
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Dan K Kaye, Michael O Osinde, and Othman Kakaire
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Adult ,Male ,Rural Population ,Domestic Violence ,medicine.medical_specialty ,Adolescent ,Population ,Poison control ,HIV Infections ,Social issues ,lcsh:Gynecology and obstetrics ,Occupational safety and health ,Young Adult ,Risk Factors ,Surveys and Questionnaires ,Environmental health ,Obstetrics and Gynaecology ,Prevalence ,Humans ,Medicine ,Uganda ,education ,lcsh:RG1-991 ,Health policy ,Medicine(all) ,education.field_of_study ,business.industry ,lcsh:Public aspects of medicine ,Health Policy ,Public health ,Obstetrics and Gynecology ,lcsh:RA1-1270 ,General Medicine ,Cross-Sectional Studies ,Logistic Models ,Sexual Partners ,Anti-Retroviral Agents ,Reproductive Medicine ,Educational Status ,Women's Health ,Domestic violence ,Female ,Rural area ,business ,Research Article - Abstract
Background Intimate partner violence (IPV) is a major public health problem in Africa and worldwide. HIV infected women face increased IPV risk. We assessed the prevalence and factors associated with IPV among HIV infected women attending HIV care in Kabale hospital, Uganda. Methods This cross-sectional study was conducted among 317 HIV infected women attending Kabale regional hospital HIV treatment centre, from March to December 2010. Participants were interviewed using an interviewer-administered questionnaire. Data was collected on socio-demographic variables, social habits, and IPV (using the abuse assessment screen and the Severity of Violence against Women Scale to identify physical, sexual and psychological violence). Characteristics of the participants who reported IPV were compared with those who did not. Multivariate logistic-regression analysis was conducted to analyze factors that were independently associated with IPV. Results The mean age of 317 respondents was 29.7 years. Twenty two (6.9%) were adolescents and 233 (73.5%) were married or cohabiting. The mean age of the spouse was 33.0 years. One hundred and eleven (35.0%) were currently on antiretroviral therapy. Lifetime prevalence of IPV (physical or sexual) was 36.6%. In the preceding 12 months, IPV (any type) was reported by 93 respondents (29.3%). This was physical for 55 (17.6%), and sexual /psychological for 38 (12.1%). On multivariate multinomial logistic regression analysis, there was a significant but inverse association between education level and physical partner violence (adjusted relative risk (ARR) 0.50, confidence limits (95% CI) 0.31-0.82, p-value = 0.007). There was a significant but inverse association between education level of respondent and sexual/psychological violence (ARR 0.47 95%CI (0.25-0.87), p-value = 0.017) Likewise, there was a significant inverse association between the education level of the spouse and psychological/sexual violence (ARR 0.57, 95% CI 0.25-0.90, p-value = 0.018). Use of antiretroviral therapy was associated with increased prevalence of any type of violence (physical, sexual or psychological) with ARR 3.04 (95%CI 1.15-8.45, p-value = 0.032). Conclusion Almost one in three women living with HIV had suffered intimate partner violence in the preceding 12 months. Nearly one in five HIV patients reported physical violence, and about one in every seven HIV patients reported sexual/psychological violence. Likewise, women who were taking antiretroviral drugs for HIV treatment were more likely to report any type of intimate partner violence (physical, sexual or psychological). The implication of these findings is that women living with HIV especially those on antiretroviral drugs should be routinely screened for intimate partner violence.
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- 2011
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21. Male involvement in birth preparedness and complication readiness for emergency obstetric referrals in rural Uganda
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Othman Kakaire, Dan K Kaye, and Michael O Osinde
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Adult ,Male ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,medicine.medical_treatment ,Prenatal care ,lcsh:Gynecology and obstetrics ,Young Adult ,Pregnancy ,Obstetrics and Gynaecology ,medicine ,Humans ,Childbirth ,Uganda ,Caesarean section ,Spouses ,Developing Countries ,Referral and Consultation ,lcsh:RG1-991 ,Vaginal delivery ,business.industry ,Obstetrics ,Research ,Obstetrics and Gynecology ,Prenatal Care ,Patient Acceptance of Health Care ,Delivery, Obstetric ,medicine.disease ,Obstetric Labor Complications ,Obstetric labor complication ,Parity ,Cross-Sectional Studies ,Reproductive Medicine ,Spouse ,Educational Status ,Female ,Emergencies ,business ,Postpartum period - Abstract
Background Every pregnant woman faces risk of life-threatening obstetric complications. A birth-preparedness package promotes active preparation and assists in decision-making for healthcare seeking in case of such complications. The aim was to assess factors associated with birth preparedness and complication-readiness as well as the level of male participation in the birth plan among emergency obstetric referrals in rural Uganda. Methods This was a cross-sectional study conducted at Kabale regional hospital maternity ward among 140 women admitted as emergency obstetric referrals in antenatal, labor or the postpartum period. Data was collected on socio-demographics and birth preparedness and what roles spouses were involved in during developing the birth plan. Any woman who attended antenatal care at least 4 times, received health education on pregnancy and childbirth danger signs, saved money for emergencies, made a plan of where to deliver from and made preparations for a birth companion, was deemed as having made a birth plan. Multivariate logistic regression analysis was conducted to analyze factors that were independently associated with having a birth plan. Results The mean age was 26.8 ± 6.6 years, while mean age of the spouse was 32.8 ± 8.3 years. Over 100 (73.8%) women and 75 (55.2%) of their spouses had no formal education or only primary level of education respectively. On multivariable analysis, Primigravidae compared to multigravidae, OR 1.8 95%CI (1.0-3.0), education level of spouse of secondary or higher versus primary level or none, OR 3.8 95%CI (1.2-11.0), formal occupation versus informal occupation of spouse, OR 1.6 95%CI (1.1-2.5), presence of pregnancy complications OR 1.4 95%CI (1.1-2.0) and the anticipated mode of delivery of caesarean section versus vaginal delivery, OR 1.6 95%CI (1.0-2.4) were associated with having a birth plan. Conclusion Individual women, families and communities need to be empowered to contribute positively to making pregnancy safer by making a birth plan.
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- 2011
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22. Perception and valuations of community-based education and service by alumni at Makerere University College of Health Sciences
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Gilbert Burnham, Dan K Kaye, Lynn Atuyambe, Nelson K. Sewankambo, Hussein Oria, Scovia Nalugo Mbalinda, Larry W. Chang, Sara Groves, Rose C. Nabirye, Andrew Mwanika, Wilson Winstons Muhwezi, and Isaac Okullo
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medicine.medical_specialty ,Teamwork ,lcsh:Public aspects of medicine ,Research ,media_common.quotation_subject ,Public health ,Public Health, Environmental and Occupational Health ,MEDLINE ,lcsh:RA1-1270 ,Focus group ,Nursing ,Perception ,medicine ,Sociology ,Rural area ,Competence (human resources) ,media_common ,Biomedical sciences - Abstract
Background Training of health professionals can be deliberately structured to enhance rural recruitment by exposing the trainees to the realities of rural life and practice through Community-Based Education and Service (COBE) programs. Few studies have surveyed the alumni of these programs to establish their post-university views and whether the positive impact of COBE programs endures into the post-university life. This study surveyed the alumni of COBE at Makerere to obtain their perceptions of the management and administration of COBE and whether COBE had helped develop their confidence as health workers, competence in primary health care and willingness and ability to work in rural communities. Objectives • To assess the efficiency of the management and administration of COBES. • To obtain the views of the impact of COBES on its alumni. Methods A mixed qualitative and quantitative study was conducted using focus group discussions (FGD) and a telephone administered questionnaire. From a total of 300 COBES alumni 150 were contacted. Twenty four Alumni (13 females and 11 males) were purposefully selected by discipline, gender and place of work, and invited for the focus group discussion. The discussions were transcribed and analyzed using a manifest content analysis table. The thematic issues from the FGDs were used to develop a structured questionnaire which was administered by telephone by the authors. The data were entered into Microsoft excel template and exported to Stata for analysis. The findings of the telephone survey were used to cross-match the views expressed during the focus group discussions. Results The alumni almost unanimously agree that the initial three years of COBES were very successful in terms of administration and coordination. COBES was credited for contributing to development of confidence as health workers, team work, communication skills, competence in primary health care and willingness to work in rural areas. The COBES alumni also identified various challenges associated with administration and coordination of COBES at Makerere. Conclusions This study has established that the positive impact of COBES endures with the alumni of the program. Health planners should take advantage of the impact of COBES and provide it with more support.
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- 2011
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