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Saccharomycopsis fibuligera, also known as Endomyces fibuliger or Saccharomyces fibuligera, is a yeast that produces ascospores and is widely found in all types of fermentation starters. It secretes α-amylase, β-glucosidase and acid protease with high efficiency and is an important functional microorganism in the fermentation of grains. Hence, S. fibuligera has high industrial application value; for example, it has a high starch conversion capacity and can synthesise trehalose from starch and it can decompose and synthesise single-cell proteins from starch and use proteins as a protein feed. It also produces aromas, esters and alcohols via fermentation; thereby, improving liquor quality. Moreover, S. fibuligera exerts an inhibitory effect on guava grey mould and can synthesise fungicides. Because S. fibuligera has excellent development potential and research value in industrial production, it has attracted considerable attention. In this study, the physicochemical, enzymatic and ester-producing properties of S. fibuligera and its effect on liquor flavour were examined. These findings will help screen excellent strains, optimise liquor fermentation conditions and improve liquor production quality.

This study presents an improved impedance method based on unbalanced synchronous excitation to identify the rotordynamic coefficients of labyrinth seals. The rotordynamic coefficient test is implemented near the cylinder resonance frequency to enlarge the influence of seal force. The force generated by the rotor unbalance is used to provide synchronous frequency excitation for the rotordynamic coefficient test. Four unique equations are set up under two sets of different rotor unbalance conditions to obtain four unknown complex rotordynamic coefficients. The factors that influence the rotordynamic coefficients of seals, namely, unbalance mass, inlet/outlet pressure ratio, and rotating speed, are considered. The dynamic coefficients are minimally affected by different rotor unbalances. The direct items are nearly equal with same signs, whereas the cross-coupled items are nearly equal with opposite signs. All coefficients increase with increasing inlet/outlet pressure ratio and rotating speed. The direct stiffness coefficients increase more quickly than the cross-coupled items. In addition, the effect stiffness and effect damping coefficients are analyzed; results indicate that both coefficients increase with increasing rotating speed.

The seal force is an important factor in turbomachineries. Therefore, the current paper puts forward an expanded seal force identification model. A seal test rig consisting of several sets of seals was prepared. Using the double-plane unbalance force identification theory in rotordynamics, the distributed seal force in the cylinder became equivalent to two selected planes. Considering the complex cylinder vibration with increasing rotating speed and inlet pressure, the cylinder was regarded as a vibration system with 4 degrees of freedom. The 4×4 impedance matrix was tested at the two selected planes using a shaker in two orthogonal directions. The equivalent seal force can be obtained by multiplying the impedance matrix with the measured change in the cylinder vibration. In the seal rig, tests were performed on the influence of inlet pressure, rotating speed, eccentricity ratio, rotor vibration, and clearance. The seal force increases almost linearly with the increasing inlet pressure, eccentricity ratio, and vibration amplitude. Furthermore, the seal force is strongly sensitive to the change in clearance between the cylinder and the rotating rotor. The phase difference between the seal force and the vibration influences the work done. If the phase difference is nearly 90°, then the work is at maximum. Moreover, the seal force applies positive force on the cylinder and negative force on the rotor.

The aim of the study was to evaluate the outcome of adenovirus-mediated p27KIP1 (Ad-p27) expression on wound healing after filtration surgery and to investigate the inhibition of cell proliferation induced by Ad-p27. We constructed the adenovirus recombinant vector Ad-p27 and administered it to a rabbit model of glaucoma filtration surgery by subconjunctival injection; phosphate-buffered saline (PBS) and mitomycin C (MMC) were used as controls. Intraocular pressure (IOP), bleb scores, and anterior chamber depths were observed during a 28-d period. Histological examinations, fluorescence observations and Western blot analyses were evaluated. Ad-p27 enhanced the surgical outcome and inhibited cell proliferation when compared with PBS. Bleb scores in the Ad-p27-treated eyes were higher than those in the PBS-treated eyes on d 7 (P

To determine the release characteristics of a 5-fluorouracil-loaded poly (lactic acid) disc (5-FU-PLA-DS) and the effect of sustained drug delivery on the success of glaucoma filtration surgery in rabbit eyes. A method of microspheres accumulated by excessive carriers was used in the preparation of the 5-FU-PLA-DS. The disc was characterized for drug loading, entrapment efficiency, in vitro release, and external morphology. It was then implanted subconjunctivally into rabbit eyes with trabeculectomy. Intraocular pressure, ocular inflammatory reaction, filtration bleb appearance, and persistence were evaluated up to postoperative d 90. A quantitative analysis of 5-fluorouracil (5-FU) was performed in the aqueous humor. Ultrasound biomicroscopy was used to assess the appearance of the filtering fistula. The 5-FU-PLA-DS was produced with the drug-loading of 3.07±0.08 mg (mean±SD). 5-FU was released for 91 d with suppressive concentrations. The decrease in intraocular pressure from baseline was significantly more marked in the 5-FU-PLA-DS-implanted eyes during postoperative d 3-90, and the persistence of bleb and filtration fistula was longer than the control eyes (P