1. Patient-Specific Modeling of Hemodynamics: Supporting Surgical Planning in a Fontan Circulation Correction
- Author
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Adam L. Dorfman, KD Lau, Theodorus M. J. van Bakel, C. Alberto Figueroa, Santi Trimarchi, and Jennifer C. Hirsch-Romano
- Subjects
Heart Defects, Congenital ,Patient-Specific Modeling ,medicine.medical_specialty ,Medical device ,Adolescent ,Computed Tomography Angiography ,Computer science ,Clinical Decision-Making ,0206 medical engineering ,Pharmaceutical Science ,Hemodynamics ,02 engineering and technology ,030204 cardiovascular system & hematology ,Coronary Angiography ,Fontan Procedure ,Surgical planning ,Time-to-Treatment ,Fontan circulation ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,Patient-Centered Care ,Genetics ,medicine ,Humans ,Ventricular Function ,Medical physics ,Genetics (clinical) ,Patient Selection ,Models, Cardiovascular ,020601 biomedical engineering ,3. Good health ,Clinical Practice ,Surgery, Computer-Assisted ,Molecular Medicine ,Female ,Cardiology and Cardiovascular Medicine - Abstract
Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are being used to calculate patient-specific hemodynamics for a variety of applications, such as disease research, noninvasive diagnostics, medical device evaluation, and surgical planning. This paper provides a concise overview of the methods to perform patient-specific computational analyses using clinical data, followed by a case study where CFD-supported surgical planning is presented in a patient with Fontan circulation complicated by unilateral pulmonary arteriovenous malformations. In closing, the challenges for implementation and adoption of CFD modeling in clinical practice are discussed.
- Published
- 2018