1. Acute kidney injury in critically ill patients with 2009 influenza A (H1N1) viral pneumonia: an observational study
- Author
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José A. Lorente, E. Echevarría, Luis Soto, G. Bujedo, Javier Hurtado, I. Cortés, Nicolás Nin, Pablo Cardinal, C. Ortega, Fernando Rios, Homero Bagnulo, F. Saldarini, A. Esteban, Francisco Arancibia, F. Frutos, and Sebastian M. Ugarte
- Subjects
Adult ,Male ,medicine.medical_specialty ,Original ,Critical Illness ,medicine.medical_treatment ,urologic and male genital diseases ,Critical Care and Intensive Care Medicine ,Risk Assessment ,law.invention ,Cohort Studies ,Influenza A Virus, H1N1 Subtype ,Risk Factors ,law ,Internal medicine ,Intensive care ,Influenza, Human ,medicine ,Humans ,Renal replacement therapy ,Intensive care medicine ,Medical Audit ,urogenital system ,business.industry ,Mortality rate ,Organ dysfunction ,Acute kidney injury ,Odds ratio ,Acute Kidney Injury ,Middle Aged ,South America ,medicine.disease ,Intensive care unit ,female genital diseases and pregnancy complications ,Intensive Care Units ,Female ,H1N1 influenza ,medicine.symptom ,business ,Kidney disease - Abstract
Objective To describe the incidence, risk factors, and impact on mortality of acute kidney injury (AKI) in patients with 2009 influenza A (H1N1) viral pneumonia requiring mechanical ventilation. Design Observational cohort study. Patients and methods AKI was defined as risk, injury or failure, according to the RIFLE classification. Early and late AKI were defined as AKI occurring on intensive care unit (ICU) day 2 or before, or after ICU day 2, respectively. Demographic data and information on organ dysfunction were collected daily. Results Of 84 patients, AKI developed in 43 patients (51%). Twenty (24%) needed renal replacement therapy. Early and late AKI were found in 28 (33%) and 15 (18%) patients, respectively. Patients with AKI, as compared with patients without AKI, had higher Acute Physiology and Chronic Health Evaluation (APACHE) II score and ICU mortality (72% versus 39%, p
- Published
- 2011
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