1. Male-to-female transmission of HIV in a cohort of hemophiliacs — Frequency, risk factors and effect of sexual counseling
- Author
-
J. K. Rockstroh, S. Ewig, T. Bauer, H. J. Dengler, T. Sauerbruch, G. Lüchters, J. Oldenburg, H. H. Brackmann, Elke Bailly, R. Kaiser, and K. E. Schneweis
- Subjects
Adult ,Male ,Microbiology (medical) ,Sexual partner ,Sexual Behavior ,Population ,HIV Infections ,Hemophilia A ,Cohort Studies ,Sex Counseling ,Sex Factors ,Acquired immunodeficiency syndrome (AIDS) ,HIV Seroprevalence ,Risk Factors ,HIV Seropositivity ,medicine ,Humans ,Risk factor ,education ,education.field_of_study ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,CD4 Lymphocyte Count ,Sexual intercourse ,Infectious Diseases ,Heterosexuality ,Immunology ,Population study ,Female ,business ,Demography - Abstract
The incidence of male-to-female transmission of HIV infection was studied in a population of 198 sexual partners of hemophiliacs who tested HIV positive since 1984. The follow-up observation period was 1987–1992. Transmission occurred in 20 (10%) cases. The analysis of risk factors for transmission was performed in a subgroup of 57 hemophiliacs with seronegative sexual partners as compared to eight transmitters. Transmitters showed a significantly more advanced immune depletion at enrollment as well as at the end of the observation period. Furthermore, transmitters had a more advanced disease at the end of the study (75% vs. 29% CDC IV; p
- Published
- 1995