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Your search keyword '"D’Esposito, Vittoria"' showing total 19 results
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19 results on '"D’Esposito, Vittoria"'

3. The role of kidney dysfunction in COVID-19 and the influence of age

Author

La Porta, Edoardo, primary, Baiardi, Paola, additional, Fassina, Lorenzo, additional, Faragli, Alessandro, additional, Perna, Simone, additional, Tovagliari, Federico, additional, Tallone, Ilaria, additional, Talamo, Giuseppina, additional, Secondo, Giovanni, additional, Mazzarello, Giovanni, additional, Esposito, Vittoria, additional, Pasini, Matteo, additional, Lupo, Francesca, additional, Deferrari, Giacomo, additional, Bassetti, Matteo, additional, and Esposito, Ciro, additional

Published
2022
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5. Cytokine signature and COVID-19 prediction models in the two waves of pandemics

Author

Cabaro, Serena, primary, D’Esposito, Vittoria, additional, Di Matola, Tiziana, additional, Sale, Silvia, additional, Cennamo, Michele, additional, Terracciano, Daniela, additional, Parisi, Valentina, additional, Oriente, Francesco, additional, Portella, Giuseppe, additional, Beguinot, Francesco, additional, Atripaldi, Luigi, additional, Sansone, Mario, additional, and Formisano, Pietro, additional

Published
2021
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6. In severe obesity, subcutaneous adipose tissue cell-derived cytokines are early markers of impaired glucose tolerance and are modulated by quercetin

Author

D’Esposito, Vittoria, primary, Ambrosio, Maria Rosaria, additional, Liguoro, Domenico, additional, Perruolo, Giuseppe, additional, Lecce, Manuela, additional, Cabaro, Serena, additional, Aprile, Marianna, additional, Marino, Ada, additional, Pilone, Vincenzo, additional, Forestieri, Pietro, additional, Miele, Claudia, additional, Bruzzese, Dario, additional, Terracciano, Daniela, additional, Beguinot, Francesco, additional, and Formisano, Pietro, additional

Published
2021
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8. Smile! (Life will be better)

Author

Esposito, Vittoria, primary, Sileno, Giuseppe, additional, Abati, Silvio, additional, Colucci, Marco, additional, Torreggiani, Massimo, additional, Grosjean, Fabrizio, additional, and Esposito, Ciro, additional

Published
2020
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9. Pro-inflammatory adipokine profile in psoriatic arthritis: results from a cross-sectional study comparing PsA subset with evident cutaneous involvement and subset “sine psoriasis”

Author

Caso, Francesco, primary, Postiglione, Loredana, additional, Covelli, Bianca, additional, Ricciardone, Margherita, additional, Di Spigna, Gaetano, additional, Formisano, Pietro, additional, D’Esposito, Vittoria, additional, Girolimetto, Nicolò, additional, Tasso, Marco, additional, Peluso, Rosario, additional, Navarini, Luca, additional, Ciccozzi, Massimo, additional, Margiotta, Domenico Paolo Emanuele, additional, Oliviero, Francesca, additional, Afeltra, Antonella, additional, Punzi, Leonardo, additional, Del Puente, Antonio, additional, Scarpa, Raffaele, additional, and Costa, Luisa, additional

Published
2019
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14. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity

Author

Raciti, Gregory A., primary, Spinelli, Rosa, additional, Desiderio, Antonella, additional, Longo, Michele, additional, Parrillo, Luca, additional, Nigro, Cecilia, additional, D’Esposito, Vittoria, additional, Mirra, Paola, additional, Fiory, Francesca, additional, Pilone, Vincenzo, additional, Forestieri, Pietro, additional, Formisano, Pietro, additional, Pastan, Ira, additional, Miele, Claudia, additional, and Beguinot, Francesco, additional

Published
2017
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16. Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population

Author

Savastano, Silvia, primary, Tarantino, Giovanni, additional, D’Esposito, Vittoria, additional, Passaretti, Federica, additional, Cabaro, Serena, additional, Liotti, Antonietta, additional, Liguoro, Domenico, additional, Perruolo, Giuseppe, additional, Ariemma, Fabiana, additional, Finelli, Carmine, additional, Beguinot, Francesco, additional, Formisano, Pietro, additional, and Valentino, Rossella, additional

Published
2015
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17. Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo

Author

Nigro, Cecilia, primary, Raciti, Gregory A., additional, Leone, Alessia, additional, Fleming, Thomas H., additional, Longo, Michele, additional, Prevenzano, Immacolata, additional, Fiory, Francesca, additional, Mirra, Paola, additional, D’Esposito, Vittoria, additional, Ulianich, Luca, additional, Nawroth, Peter P., additional, Formisano, Pietro, additional, Beguinot, Francesco, additional, and Miele, Claudia, additional

Published
2014
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18. In severe obesity, subcutaneous adipose tissue cell-derived cytokines are early markers of impaired glucose tolerance and are modulated by quercetin

Author

Dario Bruzzese, Pietro Formisano, Vincenzo Pilone, Ada Marino, Serena Cabaro, Maria Rosaria Ambrosio, Manuela Lecce, Vittoria D'Esposito, Pietro Forestieri, Claudia Miele, Marianna Aprile, Francesco Beguinot, Domenico Liguoro, Daniela Terracciano, Giuseppe Perruolo, D'Esposito, Vittoria, Ambrosio, Maria Rosaria, Liguoro, Domenico, Perruolo, Giuseppe, Lecce, Manuela, Cabaro, Serena, Aprile, Marianna, Marino, Ada, Pilone, Vincenzo, Forestieri, Pietro, Miele, Claudia, Bruzzese, Dario, Terracciano, Daniela, Beguinot, Francesco, and Formisano, Pietro

Subjects
medicine.medical_specialty, Chemokine, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous), Adipose tissue, 030209 endocrinology & metabolism, Type 2 diabetes, Proinflammatory cytokine, Impaired glucose tolerance, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Adipocyte, Medicine, 030212 general & internal medicine, Nutrition and Dietetics, biology, business.industry, Mesenchymal stem cell, nutritional and metabolic diseases, medicine.disease, Endocrinology, chemistry, biology.protein, Tumor necrosis factor alpha, business
Abstract

Background Excessive adiposity provides an inflammatory environment. However, in people with severe obesity, how systemic and local adipose tissue (AT)-derived cytokines contribute to worsening glucose tolerance is not clear. Methods Ninty-two severely obese (SO) individuals undergoing bariatric surgery were enrolled and subjected to detailed clinical phenotyping. Following an oral glucose tolerance test, participants were included in three groups, based on the presence of normal glucose tolerance (NGT), impaired glucose tolerance (IGT), or type 2 diabetes (T2D). Serum and subcutaneous AT (SAT) biopsies were obtained and mesenchymal stem cells (MSCs) were isolated, characterized, and differentiated in adipocytes in vitro. TNFA and PPARG mRNA levels were determined by qRT-PCR. Circulating, adipocyte- and MSC-released cytokines, chemokines, and growth factors were assessed by multiplex ELISA. Results Serum levels of IL-9, IL-13, and MIP-1β were increased in SO individuals with T2D, as compared with those with either IGT or NGT. At variance, SAT samples obtained from SO individuals with IGT displayed levels of TNFA which were threefold higher compared to those with NGT, but not different from those with T2D. Elevated levels of TNFα were also found in differentiated adipocytes, isolated from the SAT specimens of individuals with IGT and T2D, compared to those with NGT. Consistent with the pro-inflammatory milieu, IL-1β and IP-10 secretion was significantly higher in adipocytes from individuals with IGT and T2D. Moreover, increased levels of TNFα, both mRNA and secreted protein were detected in MSCs obtained from IGT and T2D, compared to NGT SO individuals. Exposure of T2D and IGT-derived MSCs to the anti-inflammatory flavonoid quercetin reduced TNFα levels and was paralleled by a significant decrease of the secretion of inflammatory cytokines. Conclusion In severe obesity, enhanced SAT-derived inflammatory phenotype is an early step in the progression toward T2D and maybe, at least in part, attenuated by quercetin.

Published
2021
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19. Ultrapure dialysis water obtained with additional ultrafilter may reduce inflammation in patients on hemodialysis

Author

Biagio Di Iorio, Vittoria D'Esposito, Lucia Di Micco, Domenico Russo, Pietro Formisano, Luca Nardone, Dario Bruzzese, Luigi Russo, Di Iorio, B, Di Micco, L, Bruzzese, Dario, Nardone, L, Russo, L, Formisano, Pietro, D'Esposito, Vittoria, and Russo, Domenico

Subjects
Nephrology, medicine.medical_specialty, Dialysis water, Anemia, Ultrapure water, medicine.medical_treatment, 030232 urology & nephrology, Ultrafiltration, Inflammation, 030204 cardiovascular system & hematology, Gastroenterology, Hemoglobins, 03 medical and health sciences, 0302 clinical medicine, Renal Dialysis, Internal medicine, medicine, Humans, Prospective Studies, Serum amyloid A, Aged, Aged, 80 and over, Cross-Over Studies, biology, business.industry, Dialysis patients, C-reactive protein, Water, Middle Aged, medicine.disease, Hemodialysis Solutions, Surgery, C-Reactive Protein, Ultrafilter, Erythropoietin stimulating agents, Hematinics, biology.protein, Cytokines, Original Article, Hemodialysis, Hemoglobin, Erratum, medicine.symptom, Dialysis (biochemistry), business
Abstract

Background Patients on standard dialysis, in particular those on high-flux and high-efficiency dialysis, are exposed to hundreds of liters of dialysis-water per week. The quality of dialysis-water is a factor responsible for inflammation in dialysis patients. Inflammation is a potent trigger of atherosclerosis and a pathogenetic factor in anemia, increasing mortality and morbidity in dialysis patients. Current systems for water treatment do not completely eliminate bacteria and endotoxins. This prospective study tested whether improved dialysis-water purity by an additional ultrafilter can reduce inflammation and ameliorate hemoglobin levels, with a consequent reduction in erythropoietin-stimulating agents (ESA). Methods An ultrafilter, composed of two serially positioned devices with polysulfone membranes of 2.0 and 1.0 m2, respectively, was positioned within the fluid pathway before the dialysis machine. Prevalent dialysis patients were assigned either to continue dialysis with conventional dialysis-water (control phase) or to initiate dialysis sessions with improved dialysis-water purity (study phase). After 6 months, patients were crossed over. Total study duration was 1 year. Routine chemistry, bacterial count, endotoxin levels in dialysis-water as well as blood levels of pro- and anti-inflammatory cytokines, human serum amyloid A, C-reactive protein and fraction 5 of complement were measured. Results Thirty-two patients completed the study. Mean bacterial count was lower and endotoxin levels were absent in dialysis-water obtained with the ultrafilter. At the end of the study-phase, C-reactive protein and pro-inflammatory cytokines decreased while anti-inflammatory ones increased. Hemoglobin levels were improved with lower ESA doses. Conclusions An additional ultrafilter improved dialysis-water purity, reduced levels of inflammation markers, ameliorated hemoglobin concentration with reduced ESA doses. These results remain speculative but they may generate studies to assess whether improved dialysis-water quality with an ultrafilter can reduce inflammation and improve survival of dialysis patients. Electronic supplementary material The online version of this article (doi:10.1007/s40620-017-0422-x) contains supplementary material, which is available to authorized users.

Published
2017
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