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Although apodization patterns have been adopted for the analysis of sputtering sources, the analytical solutions for the film thickness equations are yet limited to only simple conditions. Empirical formulations for thin film sputtering lacking the flexibility in dealing with multi-substrate conditions, a suitable cost-effective procedure is required to estimate the film thickness distribution. This study reports a cross-discipline simulation program, which is based on discrete particle Monte-Carlo methods and has been successfully applied to a non-imaging design to solve problems associated with sputtering uniformity. Robustness of the present method is first proved by comparing it with a typical analytical solution. Further, this report also investigates the overall all effects cause by the sizes of the deposited substrate, such that the determination of the distance between the target surface and the apodization index can be complete. This verifies the capability of the proposed method for solving the sputtering film thickness problems. The benefit is that an optical thin film engineer can, using the same optical software, design a specific optical component and consider the possible coating qualities with thickness tolerance, during the design stage.

Fresnel-like prism arrays are designed using geometric ray optics and fabricated on a curved surface according to specific focal length requirements. In this study, the tolerance of Fresnel-like prism structures on arbitrary surfaces was investigated. Compact equations (iterative and non-iterative) based on analytical formulation can be helpful in exploring the sensitivity associated with the fabrication of Fresnel-like structures. The curved surface in this study revealed a linear relationship between maximum angular tolerance and the angle of incident rays. An understanding of such linearity is a key issue in the fabrication of lenses as well as in the sensitivity formulae used for optical structures in the development of next-generation optics.

We report an intuitive approach to simulating the performance of the phosphor-based light emitting diode (LED) by using the two-light-sources model for an optimized LED lens. The optimized secondary lens shape is achieved by approaching a uniform energy distribution on the detecting plane. Both the spectrum and spatial apodization of the LED structure are discussed, and the results indicate that the two-light-sources model can solve the misleading design on the phosphor-based LED due to imperfect color mixing of light source, that one can satisfy the highly uniformity requirement for specific applications, such as display backlight or optogenetic.

Spatial light modulator is introduced for cell culturing and related illumination experiment. Two kinds of designs were used. The first type put the cell along with the bio-medium directly on top of the analyzer of the microdisplay and set a cover glass on it to retain the medium environment, which turned the microdisplay into a bio-container. The second type introduced an optical lens system placed below the spatial light modulator to focus the light spots on specific position. Details of the advantages and drawbacks for the two different approaches are discussed, and the human melanocyte cell (HMC) is introduced to prove the feasibility of the concept. Results indicate that the second type is much more suitable than the first for precision required application.

We study the biocompatibility, the magnetic clustering, and the possible transfection effect of iron particles on glia cells. Results indicate that iron particles can coexist quite well with glia cells, and the inductive migration of the cell through the vanishing of the Fe compound particles around the cell is examined. Transfection experiments also prove the feasibility of using iron particles with glia cells.

Light emitting diode (LED) has more advantages compared with a traditional incandescent light bulb and a fluorescent lamp, such as small size, low quantity of heat, long life, low power consumption, fast response, plain packaging and ease of develop ment of a frivolous short product. A methodology is proposed to improve the uniformity of the LED illumination system. As a light source in a backlight unit (BLU), the requirement for optical characteristics of a LED is different from highly directional conventional ones. New diffused-type LEDs need to be developed to fulfill the requirement of the BLU industry. A non-spherical lens is designed to optimize uniformity, and a great improvement in uniformity from 28.4 to 64% is demonstrated. In the future, it may used in an LED display to improve the unevenness of illumination.