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1. p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response

2. The onset of PI3K‐related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib

3. Angiocrine polyamine production regulates adiposity

4. Behavioural immune landscapes of inflammation

5. Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation

6. Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

7. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

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