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We consider a Dirichlet problem driven by the anisotropic (p(z), q(z))-Laplacian, with a parametric reaction exhibiting the combined effects of singular and concave-convex nonlinearities. The superlinear term may change sign. Using variational tools together with truncation and comparison techniques, we prove a global (for the parameter $$\lambda >0$$ λ > 0 ) existence and multiplicity theorem (a bifurcation-type theorem).

We study the large-time behavior of solutions for the inhomogeneous nonlinear Schrödinger equation $$\begin{aligned} iu_t+\Delta u=\lambda |u|^p+\mu |\nabla u|^q+w(x),\quad t>0,\, x\in {\mathbb {R}}^N, \end{aligned}$$ i u t + Δ u = λ | u | p + μ | ∇ u | q + w ( x ) , t > 0 , x ∈ R N , where $$N\ge 1$$ N ≥ 1 , $$p,q>1$$ p , q > 1 , $$\lambda ,\mu \in {\mathbb {C}}$$ λ , μ ∈ C , $$\lambda \ne 0$$ λ ≠ 0 , and $$u(0,\cdot ), w\in L^1_{\mathrm{loc}}({\mathbb {R}}^N,{\mathbb {C}})$$ u ( 0 , · ) , w ∈ L loc 1 ( R N , C ) . We consider both the cases where $$\mu =0$$ μ = 0 and $$\mu \ne 0$$ μ ≠ 0 , respectively. We establish existence/nonexistence of global weak solutions. In each studied case, we compute the critical exponents in the sense of Fujita, and Lee and Ni. When $$\mu \ne 0$$ μ ≠ 0 , we show that the nonlinearity $$|\nabla u|^q$$ | ∇ u | q induces an interesting phenomenon of discontinuity of the Fujita critical exponent.

The aim of this paper is to establish the existence of at least two non-zero homoclinic solutions for a nonlinear Laplacian difference equation without using Ambrosetti-Rabinowitz type-conditions. The main tools are mountain pass theorem and Palais-Smale compactness condition involving suitable functionals.

We consider a nonlinear Dirichlet problem driven by the sum of a $p$ -Laplacian and of a $q$ -Laplacian (double phase equation). In the reaction we have the combined effects of a singular term and of a gradient dependent term (convection) which is locally defined. Using a mixture of variational and topological methods, together with suitable truncation and comparison techniques, we prove the existence of a positive smooth solution.

We consider a Neumann problem driven by the (p, q)-Laplacian under the Landesman-Lazer type condition. Using the classical saddle point theorem and other classical results of the calculus of variations, we show that the problem has at least one nontrivial weak solution.

We consider a nonlinear parametric Neumann problem driven by the sum of a p-Laplacian and of a q-Laplacian and exhibiting in the reaction the competing effects of a singular term and of a resonant term. Using variational methods together with suitable truncation and comparison techniques, we show that for small values of the parameter the problem has at least two positive smooth solutions.

Therapy-related myeloid neoplasms (tMN) following successful treatment of acute myeloid leukemia (AML) are rare and poorly characterized. To evaluate the presence of a common ancestral clone, we performed whole-exome sequencing of 25 patients at AML diagnosis, tMN diagnosis (tMDS: 13; tAML: 12), and matched remission samples, identifying 607 mutations affecting 504 different genes (46 recurrently mutated). Number of mutations was higher in tAML vs. tMDS cases (median 19 vs 13 mutations, p = 0.05). Focusing on 24 genes commonly mutated in hematological malignancies, 19/25 (76%) patients were found to share mutations between AML and tMN, mostly affecting epigenetic modifiers (21/32; 66%), splicing factors (6/32; 19%), and chromatin modifiers (3/32; 9%). Analysis of remission samples identified 13 persisting mutations in 10/22 patients, affecting DNMT3A (n = 6), TET2 (n = 5), IDH1 and SRSF2 (n = 1, each). Comparison of cytogenetics revealed that 9/12 patients with a normal karyotype (NK) in AML harbored aberrations in tMN, four aberrant AML cases presented with NK in tMN, four other patients showed unrelated cytogenetic aberrations. Our study provides novel insights into the pathogenesis of tMN, hypothesizing the presence of a common ancestral clone in AML and tMN. Mutations mostly affected epigenetic modifiers, which have previously been linked to clonal hematopoiesis.

We consider a nonlinear Dirichlet equation driven by the sum of a p-Laplacian and of a Laplacian (a (p,2)-equation). The hypotheses on the reaction f(z,x) are minimal and make the energy (Euler) functional of the problem coercive. We prove two multiplicity theorems producing three and four nontrivial smooth solutions, respectively, all with sign information. We apply our multiplicity results to the particular case of a class of parametric (p,2)-equations.

We consider a semilinear Neumann problem with convection. We assume that the drift coefficient is indefinite. Using the theory of nonlinear operators of monotone type, together with truncation and comparison techniques and flow invariance arguments, we prove a multiplicity theorem producing three nontrivial smooth solutions (positive, negative and nodal).

We consider nonlinear systems driven by a general nonhomogeneous differential operator with various types of boundary conditions and with a reaction in which we have the combined effects of a maximal monotone term $A(x)$ A ( x ) and of a multivalued perturbation $F(t,x,y)$ F ( t , x , y ) which can be convex or nonconvex valued. We consider the cases where $D(A)\neq \mathbb{R}^{N}$ D ( A ) ≠ R N and $D(A)= \mathbb{R}^{N}$ D ( A ) = R N and prove existence and relaxation theorems. Applications to differential variational inequalities and control systems are discussed.

We consider a parametric nonlinear Robin problem driven by a nonlinear nonhomogeneous differential operator plus an indefinite potential. The reaction term is $$(p-1)$$-superlinear but need not satisfy the usual Ambrosetti–Rabinowitz condition. We look for positive solutions and prove a bifurcation-type result for the set of positive solutions as the parameter $$\lambda >0$$ varies. Also we prove the existence of a minimal positive solution $$u_\lambda ^*$$ and determine the monotonicity and continuity properties of the map $$\lambda \rightarrow u_\lambda ^*$$.

We consider a parametric Dirichlet problem driven by the sum of a p-Laplacian ($$p>2$$) and a Laplacian (a (p, 2)-equation). The reaction consists of an asymmetric $$(p-1)$$-linear term which is resonant as $$x \rightarrow - \infty $$, plus a concave term. However, in this case the concave term enters with a negative sign. Using variational tools together with suitable truncation techniques and Morse theory (critical groups), we show that when the parameter is small the problem has at least three nontrivial smooth solutions.

In this article, we use fixed-point methods and measure of noncompactness theory to focus on the problem of establishing the existence of at least a solution for the following functional integral equation ¶ \[u(t)=g(t,u(t))+\int_{0}^{t}G(t,s,u(s))\,ds,\quad t\in{[0,+\infty[},\] in the space of all bounded and continuous real functions on $\mathbb{R}_{+}$ , under suitable assumptions on $g$ and $G$ . Also, we establish an extension of Darbo’s fixed-point theorem and discuss some consequences.

The aim of this paper is to prove the existence of at least one nontrivial weak solution for equations involving the $$(p(\cdot ),q(\cdot ))$$-Laplace operator. The approach is variational and based on the critical point theory.

We consider a nonlinear nonparametric Dirichlet problem driven by the sum of a p-Laplacian and of a Laplacian (a (p, 2)-equation) and a reaction which involves a singular term and a $$(p-1)$$ -superlinear perturbation. Using variational tools and suitable truncation and comparison techniques, we show that the problem has two positive smooth solutions.

We investigate the existence of fixed points of self-mappings via simulation functions and measure of noncompactness. We use different classes of additional functions to get some general contractive inequalities. As an application of our main conclusions, we survey the existence of a solution for a class of integral equations under some new conditions. An example will be given to support our results.

We study the existence of fixed points for multi-valued mappings that satisfy certain generalized contractive conditions in the setting of 0-complete partial metric spaces. We apply our results to the solution of a Volterra type integral equation in ordered 0-complete partial metric spaces.

In this paper, we prove a new common fixed point theorem for four self mappings by using the notions of compatibility and subsequential continuity (alternate subcompatibility and reciprocal continuity) in metric spaces satisfying a general contractive condition of integral type. We give some examples to support the useability of our main result. Also, we obtain some fixed point theorems of Gregus type for four mappings satisfying a strict general contractive condition of integral type in metric spaces. We conclude the paper with an application of our main result to solvability of systems of functional equations.

We establish a new fixed point theorem for mappings satisfying a general contractive condition of integral type. The presented theorem generalizes the well known Ciric's fixed point theorem [Lj. B. Ciric, Generalized contractions and fixed point theorems, Publ. Inst. Math. 12 (26) (1971) 19-26]. Some examples and applications are given.

In this paper we prove some common fixed point theorems for fuzzy contraction respect to a mapping, which satisfies a condition of weak compatibility. We deduce also fixed point results for fuzzy contractive mappings in the sense of Gregori and Sapena.

The purpose of this paper is to study the existence of solutions set of integrodifferential problems in Banach spaces. We obtain our results by using fixed point theorems for multivalued mappings, under new contractive conditions, in the setting of complete b-metric spaces. Also, we present a data dependence theorem for the solutions set of fixed point problems.

We discuss multivalued weakly Picard operators on partial Hausdorff metric spaces. First, we obtain Kikkawa-Suzuki type fixed point theorems for a new type of generalized contractive conditions. Then, we prove data dependence of a fixed points set theorem. Finally, we present sufficient conditions for well-posedness of a fixed point problem. Our results generalize, complement and extend classical theorems in metric and partial metric spaces.

In this work, we establish some fixed point theorems by revisiting the notion of ψ-contractive mapping in Menger PM-spaces. One of our results (namely, Theorem2.3) may be viewed as a possible answer to the problem of existence of a fixed point for generalized type contractive mappings in M-complete Menger PM-spaces under arbitrary t-norm. Some examples are furnished to demonstrate the validity of the obtained results.

We introduce the notion ofα, λ-absolute continuity for functions of several variables and we compare it with the Hencl’s definition. We obtain that eachα, λ-absolutely continuous function isn, λ-absolutely continuous in the sense of Hencl and hence is continuous, differentiable almost everywhere and satisfies change of variables results based on a coarea formula and an area formula.

In this paper we give a common fixed point theorem for a family of mappings of a G-complete fuzzy metric space (X, M, *) into itself. From this result we deduce a common fixed point theorem for a family of mappings of a complete metric space (X, d) into itself.

We study the real valued functions having a primitive with respect to the oscillation or a primitive with respect to the oscillation up to anegligible set.

Ran and Reurings (Proc. Am. Math. Soc. 132(5):1435-1443, 2004) proved an analog of the Banach contraction principle in metric spaces endowed with a partial order and discussed some applications to matrix equations. The main novelty in the paper of Ran and Reurings involved combining the ideas in the contraction principle with those in the monotone iterative technique. Motivated by this, we present some common fixed point results for a pair of fuzzy mappings satisfying an almost generalized contractive condition in partially ordered complete metric spaces. Also we give some examples and an application to illustrate our results. MSC:46S40, 47H10, 34A70, 54E50.

We prove some coincidence and common fixed point results for three mappings satisfying a generalized weak contractive condition in ordered partial metric spaces. As application of the presented results, we give a unique fixed point result for a mapping satisfying a weak cyclical contractive condition. We also provide some illustrative examples. MSC:47H10, 54H25.

In this paper, we introduce the concepts of -compatible mappings, b-coupled coincidence point and b-common coupled fixed point for mappings F, G : X × X → X, where (X, d) is a cone metric space. We establish b-coupled coincidence and b-common coupled fixed point theorems in such spaces. The presented theorems generalize and extend several well-known comparable results in the literature, in particular the recent results of Abbas et al. [Appl. Math. Comput. 217, 195-202 (2010)]. Some examples are given to illustrate our obtained results. An application to the study of existence of solutions for a system of non-linear integral equations is also considered. 2010 Mathematics Subject Classifications: 54H25; 47H10.