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1. Osteoporosis identification among previously undiagnosed individuals with vertebral fractures

Author

Gold, L. S., Cody, R. F., Tan, W. K., Marcum, Z. A., Meier, E. N., Sherman, K. J., James, K. T., Griffith, B., Avins, A. L., Kallmes, D. F., Suri, P., Friedly, J. L., Heagerty, P. J., Deyo, R. A., Luetmer, P. H., Rundell, S. D., Haynor, D. R., and Jarvik, J. G.

Subjects
Adult, Male, Bone Density, Endocrinology, Diabetes and Metabolism, Humans, Mass Screening, Osteoporosis, Spinal Fractures, Female, Article, Osteoporotic Fractures, Aged
Abstract

Because osteoporosis is under-recognized in patients with vertebral fractures, we evaluated characteristics associated with osteoporosis identification. Most patients with vertebral fractures did not receive evaluation or treatment for osteoporosis. Black, younger, and male participants were particularly unlikely to have had recognized osteoporosis, which could increase their risk of negative outcomes.Vertebral fractures may be identified on imaging but fail to prompt evaluation for osteoporosis. Our objective was to evaluate characteristics associated with clinical osteoporosis recognition in patients who had vertebral fractures detected on their thoracolumbar spine imaging reports.We prospectively identified individuals who received imaging of the lower spine at primary care clinics in 4 large healthcare systems who were eligible for osteoporosis screening and lacked indications of osteoporosis diagnoses or treatments in the prior year. We evaluated characteristics of participants with identified vertebral fractures that were associated with recognition of osteoporosis (diagnosis code in the health record; receipt of bone mineral density scans; and/or prescriptions for anti-osteoporotic medications). We used mixed models to estimate adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs).A total of 114,005 participants (47% female; mean age 65 (interquartile range: 57-72) years) were evaluated. Of the 8579 (7%) participants with vertebral fractures identified, 3784 (44%) had recognition of osteoporosis within the subsequent year. In adjusted regressions, Black participants (OR (95% CI): 0.74 (0.57, 0.97)), younger participants (age 50-60: 0.48 (0.42, 0.54); age 61-64: 0.70 (0.60, 0.81)), and males (0.39 (0.35, 0.43)) were less likely to have recognized osteoporosis compared to white participants, adults aged 65 + years, or females.Individuals with identified vertebral fractures commonly did not have recognition of osteoporosis within a year, particularly those who were younger, Black, or male. Providers and healthcare systems should consider efforts to improve evaluation of osteoporosis in patients with vertebral fractures.

Published
2022
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5. Comparing three approaches for involving patients in research prioritization: a qualitative study of participant experiences

Author

Mary R. Scott, Danielle C. Lavallee, Donald L. Patrick, Sarah O. Lawrence, Todd C. Edwards, Jeffrey G. Jarvik, David R. Nerenz, Anjali R. Truitt, Andrew L. Avins, Sarah E. Monsell, and Zoya Bauer

Subjects
Health (social science), Patient engagement, Delphi method, lcsh:Medicine, Crowdsourcing, 03 medical and health sciences, 0302 clinical medicine, Qualitative research, Nominal group technique, 030212 general & internal medicine, Quality of experience, Patient involvement, Crowd-voting, Research priorities, lcsh:R5-920, Medical education, Descriptive statistics, business.industry, 030503 health policy & services, lcsh:R, Patient-centered outcomes research, Focus groups, Focus group, General Health Professions, Delphi survey, Thematic analysis, lcsh:Medicine (General), 0305 other medical science, business, Psychology, Research Article
Abstract

BackgroundBy participating in priority-setting activities in research, patients and members of the public help ensure that important questions are incorporated into future research agendas. Surveys, focus groups, and online crowdsourcing are increasingly used to obtain input, yet little is known about how they compare for prioritizing research topics. To address this gap, the Study of Methods for Assessing Research Topic Elicitation and pRioritization (SMARTER) evaluated participant satisfaction with the engagement experience across three prioritization activities.MethodsRespondents from Back pain Outcomes using Longitudinal Data (BOLD), a registry of patients 65 years and older with low back pain (LBP), were randomly assigned to one of three interactive prioritization activities: online crowd-voting, in-person focus groups using nominal group technique, and two rounds of a mailed survey (Delphi). To assess quality of experience, participants completed a brief survey; a subset were subsequently interviewed. We used descriptive statistics to characterize participants, and we analyzed responses to the evaluation using a mixed-methods approach, tabulating responses to Likert-scale questions and using thematic analysis of interviews to explore participant understanding of the activity and perceptions of experience.ResultsThe crowd-voting activity had 38 participants, focus groups 39, and the Delphi survey 74. Women outnumbered men in the focus groups and Delphi survey; otherwise, demographics among groups were similar, with participants being predominantly white, non-Hispanic, and college educated. Activities generated similar lists of research priorities, including causes of LBP, improving physician-patient communication, and self-care strategies. The evaluation survey was completed by 123 participants. Of these, 31 across all activities were interviewed about motivations to participate, understanding of activity goals, logistics, clarity of instructions, and the role of patients in research. Focus group participants rated their experience highest, in both the evaluation and interviews.ConclusionCommon methods for research prioritization yielded similar priorities but differing perceptions of experience. Such comparative studies are rare but important in understanding methods to involve patients and the public in research. Preferences for different methods may vary across stakeholder groups; this warrants future study.Trial registrationNICHSR,HSRP20152274. Registered 19 February 2015.

Published
2020
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6. Effects of Including Epidemiologic Data in Lumbar Spine Imaging Reports on Prescribing Non-Opioid Medications for Pain

Author

Marcum, Zachary A., primary, Gold, Laura S., additional, James, Kathryn T., additional, Meier, Eric N., additional, Turner, Judith A., additional, Kallmes, David F., additional, Cherkin, Daniel C., additional, Deyo, Richard A., additional, Sherman, Karen J., additional, Luetmer, Patrick H., additional, Avins, Andrew L., additional, Griffith, Brent, additional, Friedly, Janna L., additional, Suri, Pradeep, additional, Heagerty, Patrick J., additional, and Jarvik, Jeffrey G., additional

Published
2021
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9. Comparing three approaches for involving patients in research prioritization: a qualitative study of participant experiences

Author

Lavallee, Danielle C., primary, Lawrence, Sarah O., additional, Avins, Andrew L., additional, Nerenz, David R., additional, Edwards, Todd C., additional, Patrick, Donald L., additional, Bauer, Zoya, additional, Truitt, Anjali R., additional, Monsell, Sarah E., additional, Scott, Mary R., additional, and Jarvik, Jeffrey G., additional

Published
2020
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10. Forest ethnography: An approach to study the environmental history and political ecology of urban forests

Author

Dexter H. Locke, John Lagrosa, Miriam Avins, Carissa Aoki, J. Morgan Grove, Katie Lautar, Steward T. A. Pickett, Laura A. Ogden, Nancy F. Sonti, and William Hall

Subjects
0106 biological sciences, Ecology, Land use, business.industry, 010604 marine biology & hydrobiology, Ecology (disciplines), Environmental resource management, Land cover, Ecological succession, Political ecology, 010603 evolutionary biology, 01 natural sciences, Urban Studies, Geography, Urban ecology, Urban forest, Environmental history, business
Abstract

A landscape succession paradigm has shaped much of our understanding about the processes of forest emergence and transformation in the United States. Drawing heavily from theory and method in environmental history, this paradigm has focused attention on the role of landscape-scale shifts in land use and land cover in the production of forests. The geography of cities is patchy, dynamic and heterogeneous, with change and differences occurring at much smaller scales (e.g. Jacobs 1961; Clay 1973) compared to coarse scale of stand replacing successions affecting rural forests (Grove et al. Ecosyst Health and Sustain 2(9):e01239, 2016; Pickett et al. Urban Ecosyst 20(1):1–14, 2017). Therefore, trying to understand how urban forests came to be, as well as what they are, requires a research approach that is specific to the land use dynamics of cities and attentive to the social life of urban forests. In response to this methodological gap, this paper describes a research approach called “forest ethnography,” which we are piloting in Baltimore, Maryland as part of the Baltimore Ecosystem Study (BES), one of the National Science Foundation’s urban Long-term Ecological Research Programs (LTER). As we describe, we propose that an urban forest ethnography approach can contribute to our understanding of both forest environmental history and urban political ecology.

Published
2018
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11. Prioritizing research topics: a comparison of crowdsourcing and patient registry

Author

Danielle C. Lavallee, Sarah E. Monsell, Bryan A. Comstock, Zoya Bauer, Donald L. Patrick, Sarah O. Lawrence, Anjali R. Truitt, Andrew L. Avins, Todd C. Edwards, Jeffrey G. Jarvik, and David R. Nerenz

Subjects
Adult, Male, Research design, Comparative Effectiveness Research, medicine.medical_specialty, Comparative effectiveness research, computer.software_genre, Crowdsourcing, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Surveys and Questionnaires, Humans, Medicine, Registries, 030212 general & internal medicine, Aged, Aged, 80 and over, Medical education, Descriptive statistics, business.industry, 030503 health policy & services, Public health, Public Health, Environmental and Occupational Health, Middle Aged, Research Design, Content analysis, Quality of Life, Female, Data mining, 0305 other medical science, business, computer, Strengths and weaknesses
Abstract

A cornerstone of patient-centered outcome research is direct patient involvement throughout the research process. Identifying and prioritizing research topics is a critical but often overlooked point for involvement, as it guides what research questions are asked. We assess the feasibility of involving individuals with low back pain in identifying and prioritizing research topics using two approaches: an existing patient registry and an online crowdsourcing platform. We compare and contrast the diversity of participants recruited, their responses, and resources involved. Eligible participants completed a survey ranking their five highest priority topics from an existing list and supplying additional topics not previously identified. We analyzed their responses using descriptive statistics and content analysis. The patient registry yielded older (mean age 72.4), mostly White (70%), and well-educated (95% high school diploma or higher) participants; crowdsourcing yielded younger (mean age 36.6 years), mostly White (82%), and well-educated (98% high school diploma or higher) participants. The two approaches resulted in similar research priorities by frequency. Both provided open-ended responses that were useful, in that they illuminate additional and nuanced research topics. Overall, both approaches suggest a preference towards topics related to diagnosis and treatment over other topics. Using a patient registry and crowdsourcing are both feasible recruitment approaches for engagement. Researchers should consider their approach, community, and resources when choosing their recruitment approach, as each approach has its own strengths and weaknesses. These approaches are likely most appropriate to supplement or to complement in-person and ongoing engagement strategies.

Published
2017
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13. Conducting a pilot randomized controlled trial of community-based mindfulness-based stress reduction versus usual care for moderate-to-severe migraine: protocol for the Mindfulness and Migraine Study (M&M)

Author

Pressman, Alice, primary, Law, Heather, additional, Stahl, Robert, additional, Scott, Alex, additional, Jacobson, Alice, additional, Dean, Lisa, additional, Sudat, Sylvia, additional, Obillo, Angelica, additional, and Avins, Andrew, additional

Published
2019
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14. World Congress Integrative Medicine & Health 2017: part two

Author

Carolyn Ee, Sharmala Thuraisingam, Marie Pirotta, Simon French, Charlie Xue, Helena Teede, Agnete E. Kristoffersen, Fuschia Sirois, Trine Stub, Jennifer Engler, Stefanie Joos, Corina Güthlin, Jennifer Felenda, Christiane Beckmann, Florian Stintzing, Roni Evans, Gert Bronfort, Daniel Keefe, Anna Taberko, Linda Hanson, Alex Haley, Haiwei Ma, Joseph Jolton, Lana Yarosh, Francis Keefe, Jung Nam, Liwanag Ojala, Mary J. Kreitzer, Careen Fink, Karin Kraft, Andrew Flower, George Lewith, Kim Harman, Beth Stuart, Felicity L. Bishop, Jane Frawley, Lilla Füleki, Eva Kiss, Tamas Vancsik, Tibor Krenacs, Martha Funabashi, Katherine A. Pohlman, Silvano Mior, Haymo Thiel, Michael D. Hill, David J. Cassidy, Michael Westaway, Jerome Yager, Eric Hurwitz, Gregory N. Kawchuk, Maeve O’Beirne, Sunita Vohra, Isabelle Gaboury, Chantal Morin, Katharina Gaertner, Loredana Torchetti, Martin Frei-Erb, Michael Kundi, Michael Frass, Eugenia Gallo, Valentina Maggini, Mattia Comite, Francesco Sofi, Sonia Baccetti, Alfredo Vannacci, Mariella Di Stefano, Maria V. Monechi, Luigi Gori, Elio Rossi, Fabio Firenzuoli, Rocco D. Mediati, Giovanna Ballerini, Paula Gardiner, Anna S. Lestoquoy, Lily Negash, Sarah Stillman, Prachi Shah, Jane Liebschutz, Pamela Adelstein, Christine Farrell-Riley, Ivy Brackup, Brian Penti, Robert Saper, Isabel Giralt Sampedro, Gilda Carvajal, Andreas Gleiss, Marie M. Gross, Dorothea Brendlin, Jonas Röttger, Wiebke Stritter, Georg Seifert, Noelle Grzanna, Rainer Stange, Peter W. Guendling, Wen Gu, Yan Lu, Jie Wang, Chengcheng Zhang, Hua Bai, Yuxi He, Xiaoxu Zhang, Zhengju Zhang, Dali Wang, Fengxian Meng, Alexander Hagel, Heinz Albrecht, Claudia Vollbracht, Wolfgang Dauth, Wolfgang Hagel, Francesco Vitali, Ingo Ganzleben, Hans Schultis, Peter Konturek, Jürgen Stein, Markus Neurath, Martin Raithel, Bianka Krick, Heidemarie Haller, Petra Klose, Gustav Dobos, Sherko Kümmel, Holger Cramer, Felix J. Saha, Anna Kowoll, Barbara Ebner, Bettina Berger, Kyung-Eun Choi, Lisha He, Han Wang, X. He, C. Gu, Y. Zhang, Linhua Zhao, Xiaolin Tong, Xinhui He, Chengjuan Gu, Ying Zhang, Robin S. T. Ho, Vincent C. H. Chung, Xinyin Wu, Charlene H. L. Wong, Justin C. Y. Wu, Samuel Y. S. Wong, Alexander Y. L. Lau, Regina W. S. Sit, Wendy Wong, Michelle Holmes, Felicity Bishop, Lynn Calman, Dave Newell, Jonathan Field, Win L. Htut, Dongwoon Han, Da I. Choi, Soo J. Choi, Ha Y. Kim, Jung H. Hwang, Ching W. Huang, Bo H. Jang, Fang P. Chen, Seong G. Ko, Wenjing Huang, De Jin, Fengmei Lian, Soobin Jang, Kyeong H. Kim, Eun K. Lee, Seung H. Sun, Ho Y. Go, Youme Ko, Sunju Park, Yong C. Shin, Hubert Janik, Natalie Greiffenhagen, Jürgen Bolte, Mariusz Jaworski, Miroslawa Adamus, Aleksandra Dobrzynska, Michael Jeitler, Jessica Jaspers, Christel von Scheidt, Barbara Koch, Andreas Michalsen, Nico Steckhan, Christian Kessler, Wen-jing Huang, Bing Pang, Feng-Mei Lian, Miek Jong, Erik Baars, Anja Glockmann, Harald Hamre, Mosaburo Kainuma, Aya Murakami, Toshio Kubota, Daisuke Kobayashi, Yasuhiro Sumoto, Norihiro Furusyo, Shin-Ichi Ando, Takao Shimazoe, Olaf Kelber, S. Verjee, Eva Gorgus, Dieter Schrenk, Kathi Kemper, Ellie Hill, Nisha Rao, Gregg Gascon, John Mahan, Gunver Kienle, Jörg Dietrich, Claudia Schmoor, Roman Huber, Weon H. Kim, Mansoor Ahmed, Luzhu He, Jung Hye Hwang, Nora Meggyeshazi, Csaba Kovago, Anne K. Klaus, Roland Zerm, Danilo Pranga, Thomas Ostermann, Marcus Reif, Hans Broder von Laue, Benno Brinkhaus, Matthias Kröz, Daniela Rodrigues Recchia, Hans B. von Laue, Christien T. Klein-Laansma, Mats Jong, Cornelia von Hagens, Jean P. Jansen, Herman van Wietmarschen, Miek C. Jong, Seung-Ho Sun, Ho-Yeon Go, Chan-Yong Jeon, Yun-Kyung Song, Seong-Gyu Ko, Anna K. Koch, Sybille Rabsilber, Romy Lauche, Jost Langhorst, Milena Trifunovic-Koenig, Evi Koster, Diana Delnoij, Lena Kroll, Kathrin Weiss, Ai Kubo, Sarah Hendlish, Andrea Altschuler, Nancy Connolly, Andy Avins, Jon Wardle, David Lee, David Sibbritt, Jon Adams, Crystal Park, Gita Mishra, Johann Lechner, Inseon Lee, Younbyoung Chae, Jisu Lee, Seung H. Cho, Yujin Choi, Jee Y. Lee, Han S. Ryu, Sung S. Yoon, Hye K. Oh, Lyun K. Hyun, Jin O. Kim, Seong W. Yoon, Ju-Yeon Lee, Sang-Hoon Shin, Min Jang, Indra Müller, So-Hyun Janson Park, Lance Laird, Suzanne Mitchell, Xiaofei Li, Yunhui Wang, Jianhua Zhen, He Yu, Tiegang Liu, Xiaohong Gu, Hui Liu, Weiguo Ma, Xuezheng Shang, Yu Bai, Wei Liu, Collin Rooney, Amos Smith, Shirlene Lopes, Marcelo Demarzo, Maria do Patrocínio Nunes, Peter Lorenz, Carsten Gründemann, Miriam Heinrich, Manuel Garcia-Käufer, Franziska Grunewald, Silke Messerschmidt, Anja Herrick, Kim Gruber, Matthias Knödler, Carmen Steinborn, Taoying Lu, Lixin Wang, Darong Wu, Christina M Luberto, Daniel L. Hall, Emma Chad-Friedman, Suzanne Lechner, Elyse R. Park, Christina M. Luberto, Elyse Park, Janice Goodman, Sonja Luer, Matthias Heri, Klaus von Ammon, Ida Landini, Andrea Lapucci, Stefania Nobili, Enrico Mini, Clare McDermott, Selwyn Richards, Diane Cox, Sarah Frossell, Geraldine Leydon, Caroline Eyles, Hilly Raphael, Rachael Rogers, Michelle Selby, Charlotte Adler, Jo Allam, Xiangwei Bu, Honghong Zhang, Jianpeng Zhang, Michael Mikolasek, Jonas Berg, Claudia Witt, Jürgen Barth, Ivan Miskulin, Zdenka Lalic, Maja Miskulin, Albina Dumic, Damir Sebo, Aleksandar Vcev, Nasr A. A. Mohammed, Soo Jeung Choi, Hyea Bin Im, Anwesha Mukherjee, Amit Kandhare, Subhash Bodhankar, Prasad Thakurdesai, Niki Munk, Erica Evans, Amanda Froman, Matthew Kline, Matthew J. Bair, Frauke Musial, Terje Alræk, Harald J. Hamre, Lars Björkman, Vinjar M. Fønnebø, Feng-mei Lian, Qing Ni, Xiao-lin Tong, Xin-long Li, Wen-ke Liu, Shuo Feng, Xi-yan Zhao, Yu-jiao Zheng, Xue-min Zhao, Yi-qun Lin, Tian-yu Zhao, Xi-Yan Zhao, Hui Che Phd, Chen Zhang, Feng Liu, Lin-hua Zhao, Ru Ye, Cheng-juan Gu, Wenbo Peng, Diana De Carvalho, Mohamed El-Bayoumi, Bob Haig, Kimbalin Kelly, Darrell J. Wade, Emanuela Portalupi, Giampietro Gobo, Luigi Bellavita, Chiara Guglielmetti, Christa Raak, Myriam Teuber, Friedrich Molsberger, Ulrich von Rath, Ulrike Reichelt, Uta Schwanebeck, Sabine Zeil, Christian Vogelberg, Dolores Rodríguez Veintimilla, Guerrero Tapia Mery, Marisol Maldonado Villavicencio, Sandra Herrera Moran, Christian Sachse, Peter W Gündlin, Monirsadat Sahebkarkhorasani, Hoda Azizi, Dania Schumann, Tobias Sundberg, Matthew J. Leach, Susana Seca, Henry Greten, Sugir Selliah, Anu Shakya, Ha Yun Kim, Hyea B. Im, Anna Sherbakova, Gudrun Ulrich-Merzenich, Heba Abdel-Aziz, Erica Sibinga, Lindsey Webb, Jonathan Ellen, Kari Skrautvol, Dagfinn Nåden, Rhayun Song, Weronika Grabowska, Kamila Osypiuk, Gloria V. Diaz, Paolo Bonato, Moonkyoung Park, Jeffrey Hausdorff, Michael Fox, Lewis R. Sudarsky, Daniel Tarsy, James Novakowski, Eric A. Macklin, Peter M. Wayne, Inok Hwang, Sukhee Ahn, Myung-Ah Lee, Min K. Sohn, Oleg Sorokin, Dagmar Heydeck, Astrid Borchert, Christoph-Daniel Hohmann, Harmut Kühn, Clemens Kirschbaum, Tobias Stalder, Barbara Stöckigt, Michael Teut, Ralf Suhr, Daniela Sulmann, Chris Streeter, Patrica Gerbarg, Marisa Silveri, Richard Brown, John Jensen, Britta Rutert, Angelika Eggert, Alfred Längler, Christine Holmberg, Jin Sun, Xin Deng, Wen-Yuan Li, Bin Wen, Nicola Robinson, Jian-Ping Liu, Hyun K. Sung, Narae Yang, Seon M. Shin, Hee Jung, Young J. Kim, Woo S. Jung, Tae Y. Park, Kiyoshi Suzuki, Toshinori Ito, Seiya Uchida, Seika Kamohara, Naoya Ono, Mitsuyuki Takamura, Ayumu Yokochi, Kazuo Maruyama, Patricio Tapia, Katarzyna Thabaut, Anja Thronicke, Megan Steele, Harald Matthes, Cornelia Herbstreit, Friedemann Schad, Jiaxing Tian, Libo Yang, Tian Tian, Hewei Zhang, Xia Tian, CongCong Wang, Qian Yun Chai, Lijuan Zhang, Ruyu Xia, Na Huang, Yutong Fei, Jianpin Liu, Natalie Trent, Mindy Miraglia, Jeffrey Dusek, Edi Pasalis, Sat B. Khalsa, Milena Trifunovic-König, Anna Koch, Lisa Uebelacker, Geoffrey Tremont, Lee Gillette, Gary Epstein-Lubow, David Strong, Ana Abrantes, Audrey Tyrka, Tanya Tran, Brandon Gaudiano, Ivan Miller, Gerhild Ullmann, Yuhua Li, Sujata Vaidya, Vinod Marathe, Ana C. Vale, Jacquelyne Motta, Fabíola Donadão, Angela C. Valente, Luana C. Carvalho Valente, Ricardo Ghelman, Dusan Vesovic, Dragan Jevdic, Aleksandar Jevdic, Katarina Jevdic, Mihael Djacic, Dragica Letic, Drago Bozic, Marija Markovic, Slobodan Dunjic, Gordana Ruscuklic, Dezire Baksa, Kenan Vrca, Ann Vincent, Dietlind Wahner-Roedler, Mary Whipple, Maria M. Vogelius, Iris Friesecke, Peter W. Gündling, Saswati Mahapatra, Rebecca Hynes, Kimberly Van Rooy, Sherry Looker, Aditya Ghosh, Brent Bauer, Susanne Cutshall, Harald Walach, Ana Borges Flores, Michael Ofner, Andreas Kastner, Gerhard Schwarzl, Hermann Schwameder, Nathalie Alexander, Gerda Strutzenberger, Xianwei Bu, Jianping Zhang, Shang Wang, Jinfeng Shi, Yu Hao, Jun Wu, Zeji Qiu, Yuh-Hai Wang, Chi-Jung Lou, Sam Watts, Peter Wayne, Gloria Vergara-Diaz, Brian Gow, Jose Miranda, Lewis Sudarsky, Eric Macklin, Kathrin Wode, Jenny Bergqvist, Britt-Marie Bernhardsson, Johanna Hök Nordberg, Lena Sharp, Roger Henriksson, Yeonju Woo, Min K. Hyun, Hao Wu, Tian-Fang Wang, Yan Zhao, Yu Wei, Lei Tian, Lei He, Xue Wang, Ruohan Wu, Mei Han, Patrina H. Y. Caldwell, Shigang Liu, Jing Zhang, Jianping Liu, Qianyun Chai, Zhongning Guo, Congcong Wang, Zhijun Liu, Xun Li, I. J. Yang, V. Ruberio Lincha, S. H. Ahn, D. U. Lee, H. M. Shin, Lu Yang, N. Yang, H. Sung, S. M. Shin, H. Y. Go, H. Jung, Y. Kim, T. Y. Park, Angela Yap, Yu H. Kwan, Chuen S. Tan, Syed Ibrahim, Seng B. Ang, Alfred Yayi, Jeong E. Yoo, Ho R. Yoo, Sae B. Jang, Hye L. Lee, Ala’a Youssef, Shahira Ezzat, Amira Abdel Motaal, Hesham El-Askary, Xiaotong Yu, Yashan Cui, Younghee Yun, Jin-Hyang Ahn, Bo-Hyung Jang, Kyu-Seok Kim, Inhwa Choi, Augustina Glinz, Fadime ten Brink, Arnd Büssing, Christoph Gutenbrunner, Bert Helbrecht, Tiesheng Fang, Fengxion Meng, Zhiming Shen, Ruixin Zhang, Fan Wu, Ming Li, Xinyun Xuan, Xueyong Shen, Ke Ren, Brian Berman, Zian Zheng, Yuxiang Wan, Xueyan Ma, Fei Dong, Suzie Zick, Richard Harris, Go E. Bae, Jung N. Kwon, Hye Y. Lee, Jong K. Nam, Sang D. Lee, Dong H. Lee, Ji Y. Han, Young J. Yun, Ji H. Lee, Hye L. Park, Seong H. Park, Chiara Bocci, Giovanni B. Ivaldi, Ilaria Vietti, Ilaria Meaglia, Marta Guffi, Rubina Ruggiero, Marita Gualea, Emanuela Longa, Massimo Bonucci, Sarah Croke, Lourdes Diaz Rodriguez, Juan C. Caracuel-Martínez, Manuel F. Fajardo-Rodríguez, Angélica Ariza-García, Francisca García-De la Fuente, Manuel Arroyo-Morales, Maria S. Estrems, Vicente G. Gómez, Mónica Valero Sabater, Rosaria Ferreri, Simonetta Bernardini, Roberto Pulcri, Franco Cracolici, Massimo Rinaldi, Claudio Porciani, Peter Fisher, John Hughes, Ariadna Mendoza, Hugh MacPherson, Jacqueline Filshie, Antonia Di Francesco, Alberto Bernardini, Monica Messe, Vincenzo Primitivo, Piera A. Iasella, Monica Taminato, Jaqueline Do Carmo Alcantara, Katia R. De Oliveira, Debora C. De Azevedo Rodrigues, Juliana R. Campana Mumme, Olga K. Matsumoto Sunakozawa, Vicente Odone Filho, Joshua Goldenberg, Andrew Day, Masa Sasagawa, Lesley Ward, Kieran Cooley, Thora Gunnarsdottir, Ingibjorg Hjaltadottir, Mahdie Hajimonfarednejad, Nicole Hannan, Rut Hellsing, Susanne Andermo, Maria Arman, Iris von Hörsten, Patricia Vásquez Torrielo, Carmen L. Andrade Vilaró, Francisco Cerda Cabrera, Henny Hui, Eric Ziea, Dora Tsui, Joyce Hsieh, Christine Lam, Edith Chan, Mark P. Jensen, Samuel L. Battalio, Joy Chan, Karlyn A. Edwards, Kevin J. Gertz, Melissa A. Day, Leslie H. Sherlin, Dawn M. Ehde, Bo-Hyoung Jang, Anja Börner, Jihong Lee, Boram Lee, Gyu T. Chang, Alejandra Menassa, Yoshiharu Motoo, Jürgen Müller, Sabine Rabini, Bettina Vinson, Martin Storr, Martin Niemeijer, Joop Hoekman, Wied Ruijssenaaars, Faith C. Njoku, Arne J. Norheim, Filiz Okumus, and Halime Oncu-Celik

Subjects
03 medical and health sciences, 0302 clinical medicine, Complementary and alternative medicine, 05 social sciences, 050301 education, 030212 general & internal medicine, General Medicine, 0503 education
Published
2017
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16. Audio recordings of mindfulness-based stress reduction training to improve cancer patients’ mood and quality of life—a pilot feasibility study

Author

Peter Gordon, Elana Rosenbaum, Andrew L. Avins, Sandra Canales, and Andrea Altschuler

Subjects
Adult, Male, medicine.medical_specialty, Mindfulness, Pilot Projects, Hospital Anxiety and Depression Scale, Affect (psychology), Mindfulness-based stress reduction, Quality of life, Neoplasms, Humans, Medicine, Aged, Psychiatric Status Rating Scales, Mind-Body Therapies, business.industry, Attendance, Middle Aged, Clinical trial, Affect, Meditation, Treatment Outcome, Mood, Oncology, Quality of Life, Physical therapy, Feasibility Studies, Female, business, Stress, Psychological
Abstract

Mindfulness-based stress reduction (MBSR), typically taught in eight weekly classes, helps patients cope with illness, including cancer. Current research is almost exclusively based on post-treatment class attendance. Research suggests that short courses and alternative delivery techniques may also be beneficial. This pilot study assessed whether it would be feasible for cancer patients receiving chemotherapy to listen to MBSR audio recordings individually during treatment and at home and evaluate whether the intervention shows preliminary evidence of efficacy to improve patients’ mood and quality of life (QoL). Patients were recruited from two oncology clinics. Inclusion criteria included a score ≥8 on the Hospital Anxiety and Depression Scale (HADS). Participants were asked to listen to study CDs containing MBSR instructions at least 5 days/week for 3 months and to maintain study diaries of their meditation practices. Twenty-three patients enrolled in the study, and 20 (87%; 95% confidence interval (CI), 66% to 97%) completed the study protocol. Analysis showed that participants listened to study CDs an average of 39 times during the study; mean HADS scores declined from 18.3 to 12.2 (change = −6.1 points; 95% CI, −2.9 to −9.4). Participants reported subjectively that participation improved their mood and QoL. This pilot study demonstrates the feasibility of investigating an individual audio MBSR intervention for patients with cancer and provides preliminary evidence that MBSR may benefit chemotherapy patients’ mood and QoL. Fully powered comparative clinical trials to asses this MBSR modality to help improve mood and QoL for patients receiving chemotherapy are feasible and needed.

Published
2011
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18. Using Natural Language Processing of Free-Text Radiology Reports to Identify Type 1 Modic Endplate Changes

Author

Huhdanpaa, Hannu T., primary, Tan, W. Katherine, additional, Rundell, Sean D., additional, Suri, Pradeep, additional, Chokshi, Falgun H., additional, Comstock, Bryan A., additional, Heagerty, Patrick J., additional, James, Kathryn T., additional, Avins, Andrew L., additional, Nedeljkovic, Srdjan S., additional, Nerenz, David R., additional, Kallmes, David F., additional, Luetmer, Patrick H., additional, Sherman, Karen J., additional, Organ, Nancy L., additional, Griffith, Brent, additional, Langlotz, Curtis P., additional, Carrell, David, additional, Hassanpour, Saeed, additional, and Jarvik, Jeffrey G., additional

Published
2017
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19. World Congress Integrative Medicine & Health 2017: part two

Author

Ee, Carolyn, primary, Thuraisingam, Sharmala, additional, Pirotta, Marie, additional, French, Simon, additional, Xue, Charlie, additional, Teede, Helena, additional, Kristoffersen, Agnete E., additional, Sirois, Fuschia, additional, Stub, Trine, additional, Engler, Jennifer, additional, Joos, Stefanie, additional, Güthlin, Corina, additional, Felenda, Jennifer, additional, Beckmann, Christiane, additional, Stintzing, Florian, additional, Evans, Roni, additional, Bronfort, Gert, additional, Keefe, Daniel, additional, Taberko, Anna, additional, Hanson, Linda, additional, Haley, Alex, additional, Ma, Haiwei, additional, Jolton, Joseph, additional, Yarosh, Lana, additional, Keefe, Francis, additional, Nam, Jung, additional, Ojala, Liwanag, additional, Kreitzer, Mary J., additional, Fink, Careen, additional, Kraft, Karin, additional, Flower, Andrew, additional, Lewith, George, additional, Harman, Kim, additional, Stuart, Beth, additional, Bishop, Felicity L., additional, Frawley, Jane, additional, Füleki, Lilla, additional, Kiss, Eva, additional, Vancsik, Tamas, additional, Krenacs, Tibor, additional, Funabashi, Martha, additional, Pohlman, Katherine A., additional, Mior, Silvano, additional, Thiel, Haymo, additional, Hill, Michael D., additional, Cassidy, David J., additional, Westaway, Michael, additional, Yager, Jerome, additional, Hurwitz, Eric, additional, Kawchuk, Gregory N., additional, O’Beirne, Maeve, additional, Vohra, Sunita, additional, Gaboury, Isabelle, additional, Morin, Chantal, additional, Gaertner, Katharina, additional, Torchetti, Loredana, additional, Frei-Erb, Martin, additional, Kundi, Michael, additional, Frass, Michael, additional, Gallo, Eugenia, additional, Maggini, Valentina, additional, Comite, Mattia, additional, Sofi, Francesco, additional, Baccetti, Sonia, additional, Vannacci, Alfredo, additional, Di Stefano, Mariella, additional, Monechi, Maria V., additional, Gori, Luigi, additional, Rossi, Elio, additional, Firenzuoli, Fabio, additional, Mediati, Rocco D., additional, Ballerini, Giovanna, additional, Gardiner, Paula, additional, Lestoquoy, Anna S., additional, Negash, Lily, additional, Stillman, Sarah, additional, Shah, Prachi, additional, Liebschutz, Jane, additional, Adelstein, Pamela, additional, Farrell-Riley, Christine, additional, Brackup, Ivy, additional, Penti, Brian, additional, Saper, Robert, additional, Sampedro, Isabel Giralt, additional, Carvajal, Gilda, additional, Gleiss, Andreas, additional, Gross, Marie M., additional, Brendlin, Dorothea, additional, Röttger, Jonas, additional, Stritter, Wiebke, additional, Seifert, Georg, additional, Grzanna, Noelle, additional, Stange, Rainer, additional, Guendling, Peter W., additional, Gu, Wen, additional, Lu, Yan, additional, Wang, Jie, additional, Zhang, Chengcheng, additional, Bai, Hua, additional, He, Yuxi, additional, Zhang, Xiaoxu, additional, Zhang, Zhengju, additional, Wang, Dali, additional, Meng, Fengxian, additional, Hagel, Alexander, additional, Albrecht, Heinz, additional, Vollbracht, Claudia, additional, Dauth, Wolfgang, additional, Hagel, Wolfgang, additional, Vitali, Francesco, additional, Ganzleben, Ingo, additional, Schultis, Hans, additional, Konturek, Peter, additional, Stein, Jürgen, additional, Neurath, Markus, additional, Raithel, Martin, additional, Krick, Bianka, additional, Haller, Heidemarie, additional, Klose, Petra, additional, Dobos, Gustav, additional, Kümmel, Sherko, additional, Cramer, Holger, additional, Saha, Felix J., additional, Kowoll, Anna, additional, Ebner, Barbara, additional, Berger, Bettina, additional, Choi, Kyung-Eun, additional, He, Lisha, additional, Wang, Han, additional, He, X., additional, Gu, C., additional, Zhang, Y., additional, Zhao, Linhua, additional, Tong, Xiaolin, additional, He, Xinhui, additional, Gu, Chengjuan, additional, Zhang, Ying, additional, Ho, Robin S. T., additional, Chung, Vincent C. H., additional, Wu, Xinyin, additional, Wong, Charlene H. L., additional, Wu, Justin C. Y., additional, Wong, Samuel Y. S., additional, Lau, Alexander Y. L., additional, Sit, Regina W. S., additional, Wong, Wendy, additional, Holmes, Michelle, additional, Bishop, Felicity, additional, Calman, Lynn, additional, Newell, Dave, additional, Field, Jonathan, additional, Htut, Win L., additional, Han, Dongwoon, additional, Choi, Da I., additional, Choi, Soo J., additional, Kim, Ha Y., additional, Hwang, Jung H., additional, Huang, Ching W., additional, Jang, Bo H., additional, Chen, Fang P., additional, Ko, Seong G., additional, Huang, Wenjing, additional, Jin, De, additional, Lian, Fengmei, additional, Jang, Soobin, additional, Kim, Kyeong H., additional, Lee, Eun K., additional, Sun, Seung H., additional, Go, Ho Y., additional, Ko, Youme, additional, Park, Sunju, additional, Shin, Yong C., additional, Janik, Hubert, additional, Greiffenhagen, Natalie, additional, Bolte, Jürgen, additional, Jaworski, Mariusz, additional, Adamus, Miroslawa, additional, Dobrzynska, Aleksandra, additional, Jeitler, Michael, additional, Jaspers, Jessica, additional, von Scheidt, Christel, additional, Koch, Barbara, additional, Michalsen, Andreas, additional, Steckhan, Nico, additional, Kessler, Christian, additional, Huang, Wen-jing, additional, Pang, Bing, additional, Lian, Feng-Mei, additional, Jong, Miek, additional, Baars, Erik, additional, Glockmann, Anja, additional, Hamre, Harald, additional, Kainuma, Mosaburo, additional, Murakami, Aya, additional, Kubota, Toshio, additional, Kobayashi, Daisuke, additional, Sumoto, Yasuhiro, additional, Furusyo, Norihiro, additional, Ando, Shin-Ichi, additional, Shimazoe, Takao, additional, Kelber, Olaf, additional, Verjee, S., additional, Gorgus, Eva, additional, Schrenk, Dieter, additional, Kemper, Kathi, additional, Hill, Ellie, additional, Rao, Nisha, additional, Gascon, Gregg, additional, Mahan, John, additional, Kienle, Gunver, additional, Dietrich, Jörg, additional, Schmoor, Claudia, additional, Huber, Roman, additional, Kim, Weon H., additional, Ahmed, Mansoor, additional, He, Luzhu, additional, Hwang, Jung Hye, additional, Meggyeshazi, Nora, additional, Kovago, Csaba, additional, Klaus, Anne K., additional, Zerm, Roland, additional, Pranga, Danilo, additional, Ostermann, Thomas, additional, Reif, Marcus, additional, von Laue, Hans Broder, additional, Brinkhaus, Benno, additional, Kröz, Matthias, additional, Recchia, Daniela Rodrigues, additional, von Laue, Hans B., additional, Klein-Laansma, Christien T., additional, Jong, Mats, additional, von Hagens, Cornelia, additional, Jansen, Jean P., additional, van Wietmarschen, Herman, additional, Jong, Miek C., additional, Sun, Seung-Ho, additional, Go, Ho-Yeon, additional, Jeon, Chan-Yong, additional, Song, Yun-Kyung, additional, Ko, Seong-Gyu, additional, Koch, Anna K., additional, Rabsilber, Sybille, additional, Lauche, Romy, additional, Langhorst, Jost, additional, Trifunovic-Koenig, Milena, additional, Koster, Evi, additional, Delnoij, Diana, additional, Kroll, Lena, additional, Weiss, Kathrin, additional, Kubo, Ai, additional, Hendlish, Sarah, additional, Altschuler, Andrea, additional, Connolly, Nancy, additional, Avins, Andy, additional, Wardle, Jon, additional, Lee, David, additional, Sibbritt, David, additional, Adams, Jon, additional, Park, Crystal, additional, Mishra, Gita, additional, Lechner, Johann, additional, Lee, Inseon, additional, Chae, Younbyoung, additional, Lee, Jisu, additional, Cho, Seung H., additional, Choi, Yujin, additional, Lee, Jee Y., additional, Ryu, Han S., additional, Yoon, Sung S., additional, Oh, Hye K., additional, Hyun, Lyun K., additional, Kim, Jin O., additional, Yoon, Seong W., additional, Lee, Ju-Yeon, additional, Shin, Sang-Hoon, additional, Jang, Min, additional, Müller, Indra, additional, Park, So-Hyun Janson, additional, Laird, Lance, additional, Mitchell, Suzanne, additional, Li, Xiaofei, additional, Wang, Yunhui, additional, Zhen, Jianhua, additional, Yu, He, additional, Liu, Tiegang, additional, Gu, Xiaohong, additional, Liu, Hui, additional, Ma, Weiguo, additional, Shang, Xuezheng, additional, Bai, Yu, additional, Liu, Wei, additional, Rooney, Collin, additional, Smith, Amos, additional, Lopes, Shirlene, additional, Demarzo, Marcelo, additional, do Patrocínio Nunes, Maria, additional, Lorenz, Peter, additional, Gründemann, Carsten, additional, Heinrich, Miriam, additional, Garcia-Käufer, Manuel, additional, Grunewald, Franziska, additional, Messerschmidt, Silke, additional, Herrick, Anja, additional, Gruber, Kim, additional, Knödler, Matthias, additional, Steinborn, Carmen, additional, Lu, Taoying, additional, Wang, Lixin, additional, Wu, Darong, additional, Luberto, Christina M, additional, Hall, Daniel L., additional, Chad-Friedman, Emma, additional, Lechner, Suzanne, additional, Park, Elyse R., additional, Luberto, Christina M., additional, Park, Elyse, additional, Goodman, Janice, additional, Luer, Sonja, additional, Heri, Matthias, additional, von Ammon, Klaus, additional, Landini, Ida, additional, Lapucci, Andrea, additional, Nobili, Stefania, additional, Mini, Enrico, additional, McDermott, Clare, additional, Richards, Selwyn, additional, Cox, Diane, additional, Frossell, Sarah, additional, Leydon, Geraldine, additional, Eyles, Caroline, additional, Raphael, Hilly, additional, Rogers, Rachael, additional, Selby, Michelle, additional, Adler, Charlotte, additional, Allam, Jo, additional, Bu, Xiangwei, additional, Zhang, Honghong, additional, Zhang, Jianpeng, additional, Mikolasek, Michael, additional, Berg, Jonas, additional, Witt, Claudia, additional, Barth, Jürgen, additional, Miskulin, Ivan, additional, Lalic, Zdenka, additional, Miskulin, Maja, additional, Dumic, Albina, additional, Sebo, Damir, additional, Vcev, Aleksandar, additional, Mohammed, Nasr A. A., additional, Choi, Soo Jeung, additional, Im, Hyea Bin, additional, Mukherjee, Anwesha, additional, Kandhare, Amit, additional, Bodhankar, Subhash, additional, Thakurdesai, Prasad, additional, Munk, Niki, additional, Evans, Erica, additional, Froman, Amanda, additional, Kline, Matthew, additional, Bair, Matthew J., additional, Musial, Frauke, additional, Alræk, Terje, additional, Hamre, Harald J., additional, Björkman, Lars, additional, Fønnebø, Vinjar M., additional, Lian, Feng-mei, additional, Ni, Qing, additional, Tong, Xiao-lin, additional, Li, Xin-long, additional, Liu, Wen-ke, additional, Feng, Shuo, additional, Zhao, Xi-yan, additional, Zheng, Yu-jiao, additional, Zhao, Xue-min, additional, Lin, Yi-qun, additional, Zhao, Tian-yu, additional, Zhao, Xi-Yan, additional, Phd, Hui Che, additional, Zhang, Chen, additional, Liu, Feng, additional, Zhao, Lin-hua, additional, Ye, Ru, additional, Gu, Cheng-juan, additional, Peng, Wenbo, additional, De Carvalho, Diana, additional, El-Bayoumi, Mohamed, additional, Haig, Bob, additional, Kelly, Kimbalin, additional, Wade, Darrell J., additional, Portalupi, Emanuela, additional, Gobo, Giampietro, additional, Bellavita, Luigi, additional, Guglielmetti, Chiara, additional, Raak, Christa, additional, Teuber, Myriam, additional, Molsberger, Friedrich, additional, von Rath, Ulrich, additional, Reichelt, Ulrike, additional, Schwanebeck, Uta, additional, Zeil, Sabine, additional, Vogelberg, Christian, additional, Veintimilla, Dolores Rodríguez, additional, Mery, Guerrero Tapia, additional, Villavicencio, Marisol Maldonado, additional, Moran, Sandra Herrera, additional, Sachse, Christian, additional, Gündlin, Peter W, additional, Sahebkarkhorasani, Monirsadat, additional, Azizi, Hoda, additional, Schumann, Dania, additional, Sundberg, Tobias, additional, Leach, Matthew J., additional, Seca, Susana, additional, Greten, Henry, additional, Selliah, Sugir, additional, Shakya, Anu, additional, Kim, Ha Yun, additional, Im, Hyea B., additional, Sherbakova, Anna, additional, Ulrich-Merzenich, Gudrun, additional, Abdel-Aziz, Heba, additional, Sibinga, Erica, additional, Webb, Lindsey, additional, Ellen, Jonathan, additional, Skrautvol, Kari, additional, Nåden, Dagfinn, additional, Song, Rhayun, additional, Grabowska, Weronika, additional, Osypiuk, Kamila, additional, Diaz, Gloria V., additional, Bonato, Paolo, additional, Park, Moonkyoung, additional, Hausdorff, Jeffrey, additional, Fox, Michael, additional, Sudarsky, Lewis R., additional, Tarsy, Daniel, additional, Novakowski, James, additional, Macklin, Eric A., additional, Wayne, Peter M., additional, Hwang, Inok, additional, Ahn, Sukhee, additional, Lee, Myung-Ah, additional, Sohn, Min K., additional, Sorokin, Oleg, additional, Heydeck, Dagmar, additional, Borchert, Astrid, additional, Hohmann, Christoph-Daniel, additional, Kühn, Harmut, additional, Kirschbaum, Clemens, additional, Stalder, Tobias, additional, Stöckigt, Barbara, additional, Teut, Michael, additional, Suhr, Ralf, additional, Sulmann, Daniela, additional, Streeter, Chris, additional, Gerbarg, Patrica, additional, Silveri, Marisa, additional, Brown, Richard, additional, Jensen, John, additional, Rutert, Britta, additional, Eggert, Angelika, additional, Längler, Alfred, additional, Holmberg, Christine, additional, Sun, Jin, additional, Deng, Xin, additional, Li, Wen-Yuan, additional, Wen, Bin, additional, Robinson, Nicola, additional, Liu, Jian-Ping, additional, Sung, Hyun K., additional, Yang, Narae, additional, Shin, Seon M., additional, Jung, Hee, additional, Kim, Young J., additional, Jung, Woo S., additional, Park, Tae Y., additional, Suzuki, Kiyoshi, additional, Ito, Toshinori, additional, Uchida, Seiya, additional, Kamohara, Seika, additional, Ono, Naoya, additional, Takamura, Mitsuyuki, additional, Yokochi, Ayumu, additional, Maruyama, Kazuo, additional, Tapia, Patricio, additional, Thabaut, Katarzyna, additional, Thronicke, Anja, additional, Steele, Megan, additional, Matthes, Harald, additional, Herbstreit, Cornelia, additional, Schad, Friedemann, additional, Tian, Jiaxing, additional, Yang, Libo, additional, Tian, Tian, additional, Zhang, Hewei, additional, Tian, Xia, additional, Wang, CongCong, additional, Chai, Qian Yun, additional, Zhang, Lijuan, additional, Xia, Ruyu, additional, Huang, Na, additional, Fei, Yutong, additional, Liu, Jianpin, additional, Trent, Natalie, additional, Miraglia, Mindy, additional, Dusek, Jeffrey, additional, Pasalis, Edi, additional, Khalsa, Sat B., additional, Trifunovic-König, Milena, additional, Koch, Anna, additional, Uebelacker, Lisa, additional, Tremont, Geoffrey, additional, Gillette, Lee, additional, Epstein-Lubow, Gary, additional, Strong, David, additional, Abrantes, Ana, additional, Tyrka, Audrey, additional, Tran, Tanya, additional, Gaudiano, Brandon, additional, Miller, Ivan, additional, Ullmann, Gerhild, additional, Li, Yuhua, additional, Vaidya, Sujata, additional, Marathe, Vinod, additional, Vale, Ana C., additional, Motta, Jacquelyne, additional, Donadão, Fabíola, additional, Valente, Angela C., additional, Valente, Luana C. Carvalho, additional, Ghelman, Ricardo, additional, Vesovic, Dusan, additional, Jevdic, Dragan, additional, Jevdic, Aleksandar, additional, Jevdic, Katarina, additional, Djacic, Mihael, additional, Letic, Dragica, additional, Bozic, Drago, additional, Markovic, Marija, additional, Dunjic, Slobodan, additional, Ruscuklic, Gordana, additional, Baksa, Dezire, additional, Vrca, Kenan, additional, Vincent, Ann, additional, Wahner-Roedler, Dietlind, additional, Whipple, Mary, additional, Vogelius, Maria M., additional, Friesecke, Iris, additional, Gündling, Peter W., additional, Mahapatra, Saswati, additional, Hynes, Rebecca, additional, Van Rooy, Kimberly, additional, Looker, Sherry, additional, Ghosh, Aditya, additional, Bauer, Brent, additional, Cutshall, Susanne, additional, Walach, Harald, additional, Flores, Ana Borges, additional, Ofner, Michael, additional, Kastner, Andreas, additional, Schwarzl, Gerhard, additional, Schwameder, Hermann, additional, Alexander, Nathalie, additional, Strutzenberger, Gerda, additional, Bu, Xianwei, additional, Zhang, Jianping, additional, Wang, Shang, additional, Shi, Jinfeng, additional, Hao, Yu, additional, Wu, Jun, additional, Qiu, Zeji, additional, Wang, Yuh-Hai, additional, Lou, Chi-Jung, additional, Watts, Sam, additional, Wayne, Peter, additional, Vergara-Diaz, Gloria, additional, Gow, Brian, additional, Miranda, Jose, additional, Sudarsky, Lewis, additional, Macklin, Eric, additional, Wode, Kathrin, additional, Bergqvist, Jenny, additional, Bernhardsson, Britt-Marie, additional, Nordberg, Johanna Hök, additional, Sharp, Lena, additional, Henriksson, Roger, additional, Woo, Yeonju, additional, Hyun, Min K., additional, Wu, Hao, additional, Wang, Tian-Fang, additional, Zhao, Yan, additional, Wei, Yu, additional, Tian, Lei, additional, He, Lei, additional, Wang, Xue, additional, Wu, Ruohan, additional, Han, Mei, additional, Caldwell, Patrina H. Y., additional, Liu, Shigang, additional, Zhang, Jing, additional, Liu, Jianping, additional, Chai, Qianyun, additional, Guo, Zhongning, additional, Wang, Congcong, additional, Liu, Zhijun, additional, Li, Xun, additional, Yang, I. J., additional, Lincha, V. Ruberio, additional, Ahn, S. H., additional, Lee, D. U., additional, Shin, H. M., additional, Yang, Lu, additional, Yang, N., additional, Sung, H., additional, Shin, S. M., additional, Go, H. Y., additional, Jung, H., additional, Kim, Y., additional, Park, T. Y., additional, Yap, Angela, additional, Kwan, Yu H., additional, Tan, Chuen S., additional, Ibrahim, Syed, additional, Ang, Seng B., additional, Yayi, Alfred, additional, Yoo, Jeong E., additional, Yoo, Ho R., additional, Jang, Sae B., additional, Lee, Hye L., additional, Youssef, Ala’a, additional, Ezzat, Shahira, additional, Motaal, Amira Abdel, additional, El-Askary, Hesham, additional, Yu, Xiaotong, additional, Cui, Yashan, additional, Yun, Younghee, additional, Ahn, Jin-Hyang, additional, Jang, Bo-Hyung, additional, Kim, Kyu-Seok, additional, Choi, Inhwa, additional, Glinz, Augustina, additional, ten Brink, Fadime, additional, Büssing, Arnd, additional, Gutenbrunner, Christoph, additional, Helbrecht, Bert, additional, Fang, Tiesheng, additional, Meng, Fengxion, additional, Shen, Zhiming, additional, Zhang, Ruixin, additional, Wu, Fan, additional, Li, Ming, additional, Xuan, Xinyun, additional, Shen, Xueyong, additional, Ren, Ke, additional, Berman, Brian, additional, Zheng, Zian, additional, Wan, Yuxiang, additional, Ma, Xueyan, additional, Dong, Fei, additional, Zick, Suzie, additional, Harris, Richard, additional, Bae, Go E., additional, Kwon, Jung N., additional, Lee, Hye Y., additional, Nam, Jong K., additional, Lee, Sang D., additional, Lee, Dong H., additional, Han, Ji Y., additional, Yun, Young J., additional, Lee, Ji H., additional, Park, Hye L., additional, Park, Seong H., additional, Bocci, Chiara, additional, Ivaldi, Giovanni B., additional, Vietti, Ilaria, additional, Meaglia, Ilaria, additional, Guffi, Marta, additional, Ruggiero, Rubina, additional, Gualea, Marita, additional, Longa, Emanuela, additional, Bonucci, Massimo, additional, Croke, Sarah, additional, Rodriguez, Lourdes Diaz, additional, Caracuel-Martínez, Juan C., additional, Fajardo-Rodríguez, Manuel F., additional, Ariza-García, Angélica, additional, la Fuente, Francisca García-De, additional, Arroyo-Morales, Manuel, additional, Estrems, Maria S., additional, Gómez, Vicente G., additional, Sabater, Mónica Valero, additional, Ferreri, Rosaria, additional, Bernardini, Simonetta, additional, Pulcri, Roberto, additional, Cracolici, Franco, additional, Rinaldi, Massimo, additional, Porciani, Claudio, additional, Fisher, Peter, additional, Hughes, John, additional, Mendoza, Ariadna, additional, MacPherson, Hugh, additional, Filshie, Jacqueline, additional, Di Francesco, Antonia, additional, Bernardini, Alberto, additional, Messe, Monica, additional, Primitivo, Vincenzo, additional, Iasella, Piera A., additional, Taminato, Monica, additional, Alcantara, Jaqueline Do Carmo, additional, De Oliveira, Katia R., additional, Rodrigues, Debora C. De Azevedo, additional, Mumme, Juliana R. Campana, additional, Sunakozawa, Olga K. Matsumoto, additional, Filho, Vicente Odone, additional, Goldenberg, Joshua, additional, Day, Andrew, additional, Sasagawa, Masa, additional, Ward, Lesley, additional, Cooley, Kieran, additional, Gunnarsdottir, Thora, additional, Hjaltadottir, Ingibjorg, additional, Hajimonfarednejad, Mahdie, additional, Hannan, Nicole, additional, Hellsing, Rut, additional, Andermo, Susanne, additional, Arman, Maria, additional, von Hörsten, Iris, additional, Torrielo, Patricia Vásquez, additional, Vilaró, Carmen L. Andrade, additional, Cabrera, Francisco Cerda, additional, Hui, Henny, additional, Ziea, Eric, additional, Tsui, Dora, additional, Hsieh, Joyce, additional, Lam, Christine, additional, Chan, Edith, additional, Jensen, Mark P., additional, Battalio, Samuel L., additional, Chan, Joy, additional, Edwards, Karlyn A., additional, Gertz, Kevin J., additional, Day, Melissa A., additional, Sherlin, Leslie H., additional, Ehde, Dawn M., additional, Jang, Bo-Hyoung, additional, Börner, Anja, additional, Lee, Jihong, additional, Lee, Boram, additional, Chang, Gyu T., additional, Menassa, Alejandra, additional, Motoo, Yoshiharu, additional, Müller, Jürgen, additional, Rabini, Sabine, additional, Vinson, Bettina, additional, Storr, Martin, additional, Niemeijer, Martin, additional, Hoekman, Joop, additional, Ruijssenaaars, Wied, additional, Njoku, Faith C., additional, Norheim, Arne J., additional, Okumus, Filiz, additional, and Oncu-Celik, Halime, additional

Published
2017
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21. A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia

Author

Eric Jorgenson, Nadja Makki, Walter L. Eckalbar, Andrew L. Avins, Nadav Ahituv, David C. Chen, David A. Hinds, Ling Shen, and Chao Tian

Subjects
Male, Hernia, medicine.medical_treatment, General Physics and Astronomy, Hernia, Inguinal, Genome-wide association study, Bioinformatics, Cohort Studies, Mice, ADAMTS Proteins, 80 and over, Basic Helix-Loop-Helix Transcription Factors, 2.1 Biological and endogenous factors, Aetiology, Aged, 80 and over, Genetics, Extracellular Matrix Proteins, Multidisciplinary, Middle Aged, Hernia repair, 3. Good health, surgical procedures, operative, medicine.anatomical_structure, Inguinal, Cohort, Female, Biotechnology, Adult, Connective tissue, and over, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Clinical Research, medicine, Animals, Humans, Genetic Predisposition to Disease, WT1 Proteins, Aged, Genetic association, Human Genome, General Chemistry, medicine.disease, ADAM Proteins, Inguinal hernia, Etiology, Digestive Diseases, Genome-Wide Association Study
Abstract

Inguinal hernia repair is one of the most commonly performed operations in the world, yet little is known about the genetic mechanisms that predispose individuals to develop inguinal hernias. We perform a genome-wide association analysis of surgically confirmed inguinal hernias in 72,805 subjects (5,295 cases and 67,510 controls) and confirm top associations in an independent cohort of 92,444 subjects with self-reported hernia repair surgeries (9,701 cases and 82,743 controls). We identify four novel inguinal hernia susceptibility loci in the regions of EFEMP1, WT1, EBF2 and ADAMTS6. Moreover, we observe expression of all four genes in mouse connective tissue and network analyses show an important role for two of these genes (EFEMP1 and WT1) in connective tissue maintenance/homoeostasis. Our findings provide insight into the aetiology of hernia development and highlight genetic pathways for studies of hernia development and its treatment., Inguinal hernia has high lifetime prevalence, especially in men. This genome-wide association study identifies 4 loci to be associated with inguinal hernia, and shows expression of nearby genes in mouse connective tissues.

Published
2015
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22. Spontaneous bleeding associated with Ginkgo biloba

Author

Harley Goldberg, Andrew L. Avins, Stephen Bent, and Amy Padula

Subjects
biology, Traditional medicine, business.industry, Ginkgo biloba, Ginkgo, Internal Medicine, Adult population, Medicine, biology.organism_classification, business
Abstract

BACKGROUND:Ginkgo biloba (ginkgo) is a herbal remedy used by over 2% of the adult population in the United States. Several review articles have suggested that ginkgo may increase the risk of bleeding.

Published
2005
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23. Back pain in seniors: the Back pain Outcomes using Longitudinal Data (BOLD) cohort baseline data

Author

Richard A. Deyo, Bryan A. Comstock, Kathryn T. James, David R. Nerenz, Brian W. Bresnahan, Xu Shi, Zoya Bauer, Srdjan S. Nedeljkovic, Janna L. Friedly, Patrick J. Heagerty, Judith A. Turner, Sean D. Sullivan, Andrew L. Avins, Larry Kessler, and Jeffrey G. Jarvik

Subjects
Male, medicine.medical_specialty, Databases, Factual, Sports medicine, medicine.medical_treatment, MEDLINE, Cohort Studies, Quality of life (healthcare), Rheumatology, Epidemiology, medicine, Back pain, Humans, Orthopedics and Sports Medicine, Longitudinal Studies, Registries, Aged, Pain Measurement, Aged, 80 and over, Rehabilitation, business.industry, Age Factors, Treatment Outcome, Back Pain, Cohort, Quality of Life, Physical therapy, Female, medicine.symptom, business, Research Article, Cohort study
Abstract

Background Back pain represents a substantial burden globally, ranking first in a recent assessment among causes of years lived with disability. Though back pain is widely studied among working age adults, there are gaps with respect to basic descriptive epidemiology among seniors, especially in the United States. Our goal was to describe how pain, function and health-related quality of life vary by demographic and geographic factors among seniors presenting to primary care providers with new episodes of care for back pain. Methods We examined baseline data from the Back pain Outcomes using Longitudinal Data (BOLD) registry, the largest inception cohort to date of seniors presenting to a primary care provider for back pain. The sample included 5,239 patients ≥ 65 years old with a new primary care visit for back pain at three integrated health systems (Northern California Kaiser-Permanente, Henry Ford Health System [Detroit], and Harvard Vanguard Medical Associates [Boston]). We examined differences in patient characteristics across healthcare sites and associations of patient sociodemographic and clinical characteristics with baseline patient-reported measures of pain, function, and health-related quality of life. Results Patients differed across sites in demographic and other characteristics. The Detroit site had more African-American patients (50%) compared with the other sites (7-8%). The Boston site had more college graduates (68%) compared with Detroit (20%). Female sex, lower educational status, African-American race, and older age were associated with worse functional disability as measured by the Roland-Morris Disability Questionnaire. Except for age, these factors were also associated with worse pain. Conclusions Baseline pain and functional impairment varied substantially with a number of factors in the BOLD cohort. Healthcare site was an important factor. After controlling for healthcare site, lower education, female sex, African-American race, and older age were associated with worse physical disability and all of these factors except age were associated with worse pain. Trial registration Clinical Trials.gov NCT01776242; Registration date: June 13, 2012.

Published
2014
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24. Effect of evaluator and resident gender on the American board of internal medicine evaluation scores

Author

Esther S. Hudes, Victoria Rand, Andrew L. Avins, Warren S. Browner, and Robert M. Wachter

Subjects
Male, Health Knowledge, Attitudes, Practice, medicine.medical_specialty, Educational measurement, Cross-sectional study, media_common.quotation_subject, education, MEDLINE, California, Physicians, Women, Sex Factors, Bias, Specialty Boards, Internal medicine, Internship, Internal Medicine, medicine, Humans, health care economics and organizations, media_common, business.industry, Internship and Residency, Social environment, Original Articles, Cross-Sectional Studies, Physician gender, Education, Medical, Graduate, Family medicine, Linear Models, Female, Educational Measurement, Clinical Medicine, Prejudice, business, Training program
Abstract

To examine the effects of resident and attending physician gender on the evaluation of residents in an internal medicine training program.Cross-sectional study.Large urban academic internal medicine residency program.During their first 2 years of training, 132 residents (85 men, 47 women) received a total of 974 evaluations from 255 attending physicians (203 men, 52 women) from 1989 to 1995.The primary measurements were the numerical portions of the American Board of Internal Medicine evaluation form. Separate analyses were performed for each of the nine evaluation dimensions graded on a scale of 1 to 9. The primary outcome was the difference in the average scores received by each resident from male versus female attending physicians.Compared with female trainees, male residents received significantly higher scores from male attending physicians than from female attending physicians in six of the nine dimensions: clinical judgment, history, procedures, relationships, medical care, and overall. Similar trends, not reaching conventional levels of statistical significance, were observed in the other three categories: medical knowledge, physical exam, and attitude. These differences ranged from 0.24 to 0.60 points, and were primarily due to higher grading of male residents by male attending physicians than by female attending physicians.In one academic training program, we found a significant interaction in the grading process between the gender of internal medicine residents and the gender of their attending evaluators. This study raises the possibility that subtle aspects of gender bias may exist in medical training programs.

Published
1998
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25. Case-finding instruments for depression

Author

Jeanne Miranda, Mary A. Whooley, Andrew L. Avins, and Warren S. Browner

Subjects
medicine.medical_specialty, business.industry, Internal Medicine, Primary health care, Medicine, Case finding, Psychological testing, Original Articles, business, Psychiatry, Depression (differential diagnoses), Clinical psychology
Abstract

Objective To determine the validity of a two-question case-finding instrument for depression as compared with six previously validated instruments.

Published
1997
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26. Should we reconsider the routine use of placebo controls in clinical research?

Author

Alice Pressman, Harley Goldberg, Daniel C. Cherkin, Karen J. Sherman, and Andrew L. Avins

Subjects
Research design, medicine.medical_specialty, Blinding, Placebo controls, Psychological intervention, Alternative medicine, Medicine (miscellaneous), Placebo, Placebos, Clinical trials, medicine, Humans, Pharmacology (medical), Internal validity, Intensive care medicine, Psychiatry, lcsh:R5-920, Placebo effect, business.industry, Patient Selection, Methodology, Clinical trial, Clinical research, Masking, Research Design, Controlled Clinical Trials as Topic, lcsh:Medicine (General), business
Abstract

Background Modern clinical-research practice favors placebo controls over usual-care controls whenever a credible placebo exists. An unrecognized consequence of this preference is that clinicians are more limited in their ability to provide the benefits of the non-specific healing effects of placebos in clinical practice. Methods We examined the issues in choosing between placebo and usual-care controls. We considered why placebo controls place constraints on clinicians and the trade-offs involved in the choice of control groups. Results We find that, for certain studies, investigators should consider usual-care controls, even if an adequate placebo is available. Employing usual-care controls would be of greatest value for pragmatic trials evaluating treatments to improve clinical care and for which threats to internal validity can be adequately managed without a placebo-control condition. Conclusions Intentionally choosing usual-care controls, even when a satisfactory placebo exists, would allow clinicians to capture the value of non-specific therapeutic benefits that are common to all interventions. The result could be more effective, patient-centered care that makes the best use of both specific and non-specific benefits of medical interventions.

Published
2012
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27. Do ratings on the american board of internal medicine resident evaluation form detect differences in clinical competence?

Author

Richard J. Haber and Andrew L. Avins

Subjects
medicine.medical_specialty, Educational measurement, Percentile, business.industry, Public health, MEDLINE, Internship and Residency, United States, Community hospital, Inter-rater reliability, Specialty Boards, Internal medicine, Family medicine, Public hospital, Internal Medicine, medicine, San Francisco, Clinical Competence, Educational Measurement, Forms and Records Control, Analysis of variance, business
Abstract

Objective: To determine whether raters using the American Board of Internal Medicine (ABIM) Resident Evaluation Form can detect differences among residents in clinical competence. Design: Cross-sectional study. Setting: Inpatient general medicine service in a university-affiliated public hospital. Participants: University-based internal medicine (UCIM) residents (ABIM certifying examination pass rate, 91%; mean score, 95th percentile), community hospital-based internal medicine (CHIM) residents (ABIM examination pass rate, 68%; mean score, 42nd percentile), and residents from three university-based non-internal medicine (UC non-IM) programs all assigned to the same inpatient general medicine service over a three-year period. Four hundred eighty-nine evaluations of 110 postgraduate-year-one residents were analyzed. Measurements and main results: Mean ratings for the UCIM residents were significantly higher than those for the CHIM or UC non-IM residents (analysis of variance [ANOVA], p

Published
1994
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29. Comparing recruitment strategies in a study of acupuncture for chronic back pain

Author

Daniel C. Cherkin, Partap S. Khalsa, Richard A. Deyo, Rene J. Hawkes, Laura Ichikawa, Karen J. Sherman, and Andrew L. Avins

Subjects
Male, medicine.medical_specialty, Epidemiology, Acupuncture Therapy, Alternative medicine, Health Informatics, Primary care, 03 medical and health sciences, 0302 clinical medicine, Back pain, Acupuncture, Humans, Medicine, 030212 general & internal medicine, lcsh:R5-920, business.industry, Patient Selection, Middle Aged, 3. Good health, Clinical trial, Back Pain, Chronic Disease, Linear Models, Physical therapy, Female, medicine.symptom, lcsh:Medicine (General), business, 030217 neurology & neurosurgery, Research Article, Follow-Up Studies
Abstract

Background Meeting recruitment goals is challenging for many clinical trials conducted in primary care populations. Little is known about how the use of different recruitment strategies affects the types of individuals choosing to participate or the conclusions of the study. Methods A secondary analysis was performed using data from participants recruited to a clinical trial evaluating acupuncture for chronic back pain among primary care patients in a large integrated health care organization. We used two recruitment methods: mailed letters of invitation and an advertisement in the health plan's magazine. For these two recruitment methods, we compared recruitment success (% randomized, treatment completers, drop outs and losses to follow-up), participant characteristics, and primary clinical outcomes. A linear regression model was used to test for interaction between treatment group and recruitment method. Results Participants recruited via mailed letters closely resembled those responding to the advertisement in terms of demographic characteristics, most aspects of their back pain history and current episode and beliefs and expectations about acupuncture. No interaction between method of recruitment and treatment group was seen, suggesting that study outcomes were not affected by recruitment strategy. Conclusion In this trial, the two recruitment strategies yielded similar estimates of treatment effectiveness. However, because this finding may not apply to other recruitment strategies or trial circumstances, trials employing multiple recruitment strategies should evaluate the effect of recruitment strategy on outcome. Trial registration Clinical Trials.gov NCT00065585.

Published
2009
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30. Back pain in seniors: the Back pain Outcomes using Longitudinal Data (BOLD) cohort baseline data

Author

Jarvik, Jeffrey G, primary, Comstock, Bryan A, additional, Heagerty, Patrick J, additional, Turner, Judith A, additional, Sullivan, Sean D, additional, Shi, Xu, additional, Nerenz, David R, additional, Nedeljkovic, Srdjan S, additional, Kessler, Larry, additional, James, Kathryn, additional, Friedly, Janna L, additional, Bresnahan, Brian W, additional, Bauer, Zoya, additional, Avins, Andrew L, additional, and Deyo, Richard A, additional

Published
2014
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31. Study protocol: The back pain outcomes using longitudinal data (BOLD) registry

Author

Jarvik, Jeffrey G, primary, Comstock, Bryan A, additional, Bresnahan, Brian W, additional, Nedeljkovic, Srdjan S, additional, Nerenz, David R, additional, Bauer, Zoya, additional, Avins, Andrew L, additional, James, Kathryn, additional, Turner, Judith A, additional, Heagerty, Patrick, additional, Kessler, Larry, additional, Friedly, Janna L, additional, Sullivan, Sean D, additional, and Deyo, Richard A, additional

Published
2012
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33. Study Protocol- Lumbar Epidural Steroid Injections for Spinal Stenosis (LESS): a double-blind randomized controlled trial of epidural steroid injections for lumbar spinal stenosis among older adults

Author

Friedly, Janna L, primary, Bresnahan, Brian W, additional, Comstock, Bryan, additional, Turner, Judith A, additional, Deyo, Richard A, additional, Sullivan, Sean D, additional, Heagerty, Patrick, additional, Bauer, Zoya, additional, Nedeljkovic, Srdjan S, additional, Avins, Andrew L, additional, Nerenz, David, additional, and Jarvik, Jeffrey G, additional

Published
2012
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43. The PRIME curriculum

Author

Kohlwes, R. J., primary, Shunk, R. L., additional, Avins, A., additional, Garber, J., additional, Bent, S., additional, and Shlipak, M. G., additional

Published
2006
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45. Screening for depression

Author

David A. Nardone, Mary A. Whooley, Andrew L. Avins, Jeanne Miranda, Warren S. Browner, and Susan P. Smith

Subjects
medicine.medical_specialty, business.industry, Predictive value of tests, Internal Medicine, medicine, Psychological testing, Psychiatry, business, Depression (differential diagnoses)
Published
1997
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47. Screening for depression

Author

Nardone, David A., primary, Smith, Susan P., additional, Whooley, Mary A., additional, Avins, Andrew L., additional, Miranda, Jeanne, additional, and Browner, Warren S., additional

Published
1997
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49. Screening for high cholesterol

Author

Stephen B. Hulley and Andrew L. Avins

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Internal Medicine, medicine, medicine.disease, business, High cholesterol
Published
1990
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