1. Atherogenic index of plasma may be strong predictor of subclinical atherosclerosis in patients with Behçet disease
- Author
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A. Kucuk, Miyase Ozucan, M. Cumhur Cure, Erkan Cure, Davut Sakiz, F. Yavuz, Abdullah Icli, R. Aydoğan Baykara, A. Ugur Uslu, Sulhattin Arslan, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Cüre, Erkan, and Cüre, Medine Cumhur
- Subjects
Adult ,Male ,medicine.medical_specialty ,Turkey ,Comorbidity ,Behcet's disease ,Disease ,030204 cardiovascular system & hematology ,Carotid Intima-Media Thickness ,Sensitivity and Specificity ,Severity of Illness Index ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,High-density lipoprotein ,Rheumatology ,Risk Factors ,Internal medicine ,medicine ,Humans ,Subclinical atherosclerosis ,Triglycerides ,030203 arthritis & rheumatology ,Predictive marker ,Triglyceride ,business.industry ,Behcet Syndrome ,Incidence ,Atherogenic index of plasma ,Reproducibility of Results ,Atherosclerosis ,Prognosis ,medicine.disease ,Causality ,chemistry ,Case-Control Studies ,Asymptomatic Diseases ,cardiovascular system ,Cardiology ,Carotid artery intima-media thickness ,Female ,Lipoproteins, HDL ,business ,Biomarkers ,Systemic vasculitis - Abstract
cure, erkan/0000-0001-7807-135X; Cure, Medine Cumhur/0000-0001-9253-6459; Aydogan Baykara, Rabia/0000-0003-0542-266X WOS: 000399025700011 PubMed: 27431747 Behcet's disease (BD) is a systemic vasculitis characterized by cardiovascular complications. Early diagnosis of these complications can reduce morbidity and mortality. Carotid artery intima-media thickness (cIMT) and the logarithmic value of triglyceride to high density lipoprotein ratio (atherogenic index of plasma, AIP) are good markers of atherosclerosis. the purpose of this study was to investigate whether AIP is a predictive marker of subclinical atherosclerosis in BD patients. A total of 84 BD patients (60 male, 24 female) and 84 healthy control individuals (58 male, 26 female) were included in this study. cIMT measurements were made, and AIP values were calculated. cIMT (p < 0.001) and AIP (p < 0.001) values of the BD patients were higher than those of the control group. A strong independent relationship was found between the AIP value and cIMT (beta = 0.232, p = 0.018). in the subgroup analysis, the cIMT and AIP values of male BD patients were higher than those of female BD patients. Increased AIP and cIMT values can be a good marker for subclinical atherosclerosis in BD patients, especially in male BD patients.
- Published
- 2016