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The Simons Observatory (SO) is an upcoming polarization-sensitive Cosmic Microwave Background (CMB) experiment on the Cerro Toco Plateau (Chile) with large overlap with other optical and infrared surveys (e.g., DESI, LSST, HSC). To enable the readout of \bigO(10,000) detectors in each of the four telescopes of SO, we will employ the microwave SQUID multiplexing technology. With a targeted multiplexing factor of \bigO{(1,000)}, microwave SQUID multiplexing has never been deployed on the scale needed for SO. Here we present the design of the cryogenic coaxial cable and RF component chain that connects room temperature readout electronics to superconducting resonators that are coupled to Transition Edge Sensor bolometers operating at sub-Kelvin temperatures. We describe design considerations including cryogenic RF component selection, system linearity, noise, and thermal power dissipation., 10 pages, 2 figures

The Simons Observatory will measure the cosmic microwave background temperature and polarization using a suite of new telescopes in the Atacama Desert in Chile. The Simons Observatory will use dichroic transition edge sensor (TES) bolometer arrays spanning six frequency bands from 27 to 280 GHz. The Simons Observatory will pioneer the use of a densely packed multiplexing architecture based on the microwave SQUID multiplexer ($$\mu $$mux), housing $$\sim \! 2000$$ microwave resonators, each coupled to a TES. The Simons Observatory aims to multiplex each array of $$\sim \! 2000$$ detectors with a single pair of coaxial cables and requires a multiplexing factor of $$\sim \! 1000$$. The Simons Observatory cryogenic readout system is called the universal microwave multiplexing module (UMM). The UMM couples to both horn and lenslet-coupled detector arrays and is integrated into the universal focal-plane module (UFM) after being independently characterized. We present processes we have developed for highly repeatable and automated integration methods of UMMs, which will be needed for the production of the 49 UFMs required for the first stage of the Simons Observatory.