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The Integrated Neuropsychiatric Assessment System is a portable platform for cognitive neurodynamic research and for clinical evaluations. It provides simultaneous acquisition of heart rate variability, quantitative electroencephalography and event related potentials during a neuropsychological assessment. The analysis protocol includes measures derived from dynamical systems theory including analysis of causal networks, event-dependent interregional synchronization and small world modeling.

We investigate whether causal relationships in coupled Van der Pol oscillators can be determined. Using the instantaneous phase of computer generated time series, which are unidirectionally and time dependently coupled, the technique of lagged mutual information is tested to determine its usefulness in detecting information transmission. If successful, it could assist in improving our understanding of the role of information transmission in organizing CNS activity.