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Image segmentation is an important analysis tool in the field of computer vision. In this paper, on the basis of the traditional level set method, a novel segmentation model using generalized divergences is proposed. The main advantage of generalized divergences is their smooth connection performance among various kinds of well-known and frequently used fundamental divergences with one formula. Therefore, the discrepancy between two probability distributions of segmented image parts can be measured by generalized divergences. We also found a solution to determine the optimal divergence automatically for different images. Experimental results on a variety of synthetic and natural images are presented, which demonstrate the potential of the proposed method. Compared with the previous active contour models formulated to solve the same nonparametric statistical segmentation problem, our method performs better both qualitatively and quantitatively. [ABSTRACT FROM AUTHOR]