1. Early pyloric stenosis: a case control study
- Author
-
Marie Demian, Son Nguyen, and Sherif Emil
- Subjects
Male ,medicine.medical_specialty ,Vomiting ,Pyloric muscle ,Pyloric Stenosis, Hypertrophic ,Pediatrics ,Pyloric stenosis ,Pediatric Surgery ,Ultrasound ,Diagnosis ,Pediatric surgery ,Medicine & Public Health ,Humans ,Medicine ,Pediatrics, Perinatology, and Child Health ,Family history ,Pylorus ,Retrospective Studies ,Ultrasonography ,business.industry ,Infant, Newborn ,Case-control study ,Retrospective cohort study ,General Medicine ,Length of Stay ,medicine.disease ,Surgery ,Breast Feeding ,Early Diagnosis ,Early ,medicine.anatomical_structure ,Case-Control Studies ,Pediatrics, Perinatology and Child Health ,Female ,Original Article ,medicine.symptom ,business ,Breast feeding - Abstract
Objective Pyloric stenosis (PS) is rare in the first 2 weeks of life, often leading to delays in diagnosis and treatment. We conducted a case control study to delineate the characteristics of patients with early PS (EPS). In addition, we tested the hypothesis that patients with EPS present with a smaller pylorus than older patients. Methods A database of all patients presenting with PS to a children’s hospital over a 5-year period (2002–2006) was obtained. Each patient admitted during the first 2 weeks of life (subject) was matched to a patient admitted after 4 weeks of age (control), with the same gender, electrolyte status, and treating surgeon. A single pediatric radiologist, blinded to patient age, reviewed all available ultrasounds retrospectively. Demographic, clinical, diagnostic, therapeutic, and outcome data were compared. Results During the study period, 278 pyloromyotomies were performed for PS. Sixteen patients (5.8%) presented with EPS between 2 and 14 days of life. EPS patients had a higher prevalence of positive family history (31 vs. 0%, P = 0.043), and breast milk feeding (75 vs. 31%, P = 0.045). Sonographic measurements showed a pylorus that was of significantly less length (17.1 ± 0.6 vs. 20.5 ± 0.9 mm, P = 0.006) and muscle thickness (3.5 ± 0.2 vs. 4.9 ± 0.2 mm, P
- Full Text
- View/download PDF