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Bacteriophage therapy could be a solution for the rising problem of antibiotic resistance, as described in this case for cystoprostatitis. A 71-year-old man suffers from severe disabling nocturia and dysuria, because of a cystoprostatitis with a multiresistant Klebsiella pneumoniae. Whereas antibiotic treatment only gave temporary improvement, the treatment with bacteriophages, oral and intravesical, resulted in a decline of complaints so far. Positive results of treatment with bacteriophages are documented in literature, as well as the safe use of them. Bacteriophage therapy seems promising. Randomized controlled trials are needed to research if this could be a solution for problems resolving from the increasing antibiotic resistance. [ABSTRACT FROM AUTHOR]