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Tricyclo[4.3.1.03,7]decane is also known as isotwistane, which is commonly found in the structures of natural products. This work accomplished the synthesis of this scaffold through 7 steps, including pivotal Diels–Alder and Conia-ene reactions. The optimized molecular crystal structure data obtained from density functional theory (DFT) calculation aligned with the actual values from X-ray diffraction. Building upon this, molecular electrostatic potential (MEP) and frontier molecular orbital (FMOs) analyses were performed, elucidating the relevant physicochemical properties of this framework for the first time. [ABSTRACT FROM AUTHOR]

With the increasing of wind energy, it is necessary to develop an energy storage system to level the wave of wind power, and to develop a fault current limiter for improvement of the LVRT capability of the wind farm. An innovative idea to deal with the above problem is to develop a superconducting fault current limiter-magnetic energy storage system (SFCL-MES). In this paper, we report the progress of the superconducting coil for a 1-MJ/0.5-MVA FCL-SMES system. The coil consisted of 46 double pancakes, in which 8 pancakes were made of YBCO tapes and the others were made of Bi2223 tapes; the inductance of the coil was 13.3 H, and its rated current was 388 A while the maximum magnetic field was 3.5 T. This coil had been used for a FCL-SMES system, which was installed and tested at a wind farm connected to the live power grid. [ABSTRACT FROM AUTHOR]

The fish-borne clonorchiasis caused by the oriental liver fluke Clonorchis sinensis is endemic in a number of countries with over 35 million people being infected globally. Rapid and accurate detection of C. sinensis in its intermediate host fish is important for the control and prevention of clonorchiasis in areas where the disease is endemic. In the present study, we established a loop-mediated isothermal amplification (LAMP) approach for the sensitive and rapid detection of C. sinensis metacercariae in fish. The specificity and sensitivity of primers designed from the C. sinensis cathepsins B3 gene were evaluated, and specific amplification products were obtained with C. sinensis, while no amplification products were detected with DNA of related trematodes, demonstrating the specificity of the assay. The LAMP assay was proved to be 100 times more sensitive than a conventional polymerase chain reaction for detection of C. sinensis. The established LAMP assay provides a useful tool for the rapid and sensitive detection of C. sinensis in fish, which has important implications for the effective control of human clonorchiasis. [ABSTRACT FROM AUTHOR]

A symmetric five-dentate Schiff-base ligand N,N-bis(pyridine-2-carboxaldehyde)diethylenetriamine (L) was prepared. An unusual copper(II) complex [CuCl2(L)] ⋅ H2O was obtained, when copper chloride reacted with ligand L. In the course of the coordination reaction, a ring closure reaction happens to ligand L. So, the formation process of the complex can be used for reference to synthesize the ring compound. The complex has been characterized fully by elemental analysis, IR, absorption spectra, emission spectra, and single-crystal X-ray diffraction analysis. Moreover, a reasonable reaction mechanism for forming the complex was presumed. The complex was synthesized by treating an ethanolic solution of the appropriate ligand with an equimolar amount of metallic salt. In the complex, the copper atom is five-coordinated, which can be best described as a distorted square-pyramidal geometry with a N3Cl2 donor set, and two parallel one-dimensional chains are formed by packing of the complex. [ABSTRACT FROM AUTHOR]

Heartburn, bloating, and abdominal discomfort are common problems in patients with spinal cord injury but, despite its clinical significance, little is known about the gastrointestinal effects of spinal transections- To address the potential gastrointestinal pathophysiology of spinal cord injury, we measured mouth-to-cecum transit time (MCTT) in seven subjects with paraplegia and seven with guadriplegia. Gastric emptying was studied in six subjects with quadriplegia. MCTT was significantly prolonged in patients with quadriplegia, an abnormality corrected by the administration of cisa-pride. Patients with paraplegia, in contrast to those with quadriplegia, have normal mouth-to-cecum transit time. In addition, patients with quadriplegia had neither a prolonged gastric emptying time nor a change in gastric emptying time, with cisapride. Changes in gastrointestinal transit after spinal cord injury and the improvement of mouth-to-cecum transit time in subjects with quadriplegia, but not in those with paraplegia, may be explained by an imbalance between parasympathetic and sympathetic outflows to the gastrointestinal tract in this group of subjects. [ABSTRACT FROM AUTHOR]

A new manganeses(II) complex MnLCl2 · CH3OH (L = N,N′-bis(furaldehyde)diethylenetriamine) was synthesized and characterized by X-ray crystallographic analysis. The crystals are orthorhombic, space group Pnma with cell parameters a = 20.998(6), b = 13.314(5), c = 6.785(8) Å, Z = 4, R1 = 0.0609, and wR2 = 0.2116. The coordination geometry around Mn(II) atom is a trigonal-bipyramidic containing one tridenate ligand L and two Cl− ions. [ABSTRACT FROM AUTHOR]