1. Use of venovenous ECMO for neonatal and pediatric ECMO: a decade of experience at a tertiary children's hospital.
- Author
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Carpenter, Jennifer L., Yu, Yangyang R., Cass, Darrell L., Olutoye, Oluyinka O., Thomas, James A., Burgman, Cole, Fernandes, Caraciolo J., and Lee, Timothy C.
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EXTRACORPOREAL membrane oxygenation , *CRITICAL care medicine , *TERTIARY care , *CHILD patients , *CEREBRAL hemorrhage , *CATHETERIZATION , *CEREBRAL ischemia , *CHILDREN'S hospitals , *INTENSIVE care units , *LONGITUDINAL method , *NEONATAL intensive care , *PEDIATRICS , *SPECIALTY hospitals , *NEONATAL intensive care units , *RETROSPECTIVE studies ,CEREBRAL ischemia treatment - Abstract
Background: Advances in extracorporeal membrane oxygenation (ECMO) have led to increased use of venovenous (VV) ECMO in the pediatric population. We present the evolution and experience of pediatric VV ECMO at a tertiary care institution.Methods: A retrospective cohort study from 01/2005 to 07/2016 was performed, comparing by cannulation mode. Survival to discharge, complications, and decannulation analyses were performed.Results: In total, 160 patients (105 NICU, 55 PICU) required 13 ± 11 days of ECMO. VV cannulation was used primarily in 83 patients with 64% survival, while venoarterial (VA) ECMO was used in 77 patients with 54% survival. Overall, 74% of patients (n = 118) were successfully decannulated; 57% survived to discharge. VA ECMO had a higher rate of intra-cranial hemorrhage than VV (22 vs 9%, p = 0.003). Sixteen VA patients (21%) had radiographic evidence of a cerebral ischemic insult. No cardiac complications occurred with the use of dual-lumen VV cannulas. There were no differences in complications (p = 0.40) or re-operations (p = 0.85) between the VV and VA groups.Conclusion: Dual-lumen VV ECMO can be safely performed with appropriate image guidance, is associated with a lower rate of intra-cranial hemorrhage, and may be the preferred first-line mode of ECMO support in appropriately selected NICU and PICU patients.Level Of Evidence: II. [ABSTRACT FROM AUTHOR]- Published
- 2018
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