Search

In this study, it is aimed to predict the performance of concretes obtained by using supplementary cementitious materials (SCM) before and after high temperature using artificial neural network. Thus, in addition to contributing to sustainable development and circular economy by using waste materials in concrete production, predicting concrete strength using artificial neural network without the need for experimental studies will provide a great advantage in practice. In addition, it will also contribute to the literature in terms of determining the optimum amount of metakaolin to be used with fly ash in concrete production. Metakaolin, silica fume and fly ash were used as SCM in different proportions in concrete mixes. Accordingly, a total of 22 concrete series were prepared, one of which was the control series. Porosity, ultrasonic pulse velocity, pressure and tensile strength tests were applied to the series at the end of 7th, 28th and 90th curing periods before high temperature. In order to determine the strength losses after elevated temperature, porosity and compressive strength tests were applied at temperatures of 400, 600 and 800 °C. Mineral additive series showed positive mechanical properties up to 20%. However, it has been observed that the use of fly ash after a certain rate causes a decrease in strength. After elevated temperature, strength loss was observed in all series due to the increase in temperature, while it was observed that the rate of being affected by elevated temperature decreased as the percentage of metakaolin increased. Optimum mineral additive usage percentages were determined as 10% fly ash and 15% metakaolin. On the other hand, the use of mineral additives above the optimum level caused the performance of the concrete to decrease. Then, the concrete compression strengths obtained at 7th, 28th, and 90th days and at 400, 600 and 800 °C temperatures are taken as the outputs of the ANN. The artificial neural network provided the closest results to experimental data. Moreover, to prove the predictive performance of ANN, a comparative analysis was made with GPR, SVM and LR and the smallest value of the RMSE value is obtained with the ANN model. Finally, a fivefold cross-validation criteria was used to objectively present the performance of the model. [ABSTRACT FROM AUTHOR]

Background: Thyroid hormones play an important role in the regulation of glucose metabolism. Recently, some studies determined the relationship between diabetes and abnormality of indices of thyroid hormone sensitivity. Thyroid dysfunction may play a role in the etiology of gestational diabetes mellitus (GDM).In the present study, we aim to determine central and peripheral thyroid hormone resistance by evaluating indices of thyroid hormone sensitivity and thyroid function tests and to investigate its effect on the etiology of GDM.A total of 1416 euthyroid pregnant women were included in this study. Of these, 241 (17%) had GDM and 1175 (83%) did not have GDM. We evaluated the association of indices of sensitivity to thyroid hormones including TFQIFT4, TFQIFT3, TSHI, TT4RI, and FT3/FT4, with GDM in pregnant euthyroid women.We found higher FT3, TFQIFT3, and FT3/FT4 ratio in the GDM group. The present study also showed that significantly increased FT3 and TFQIFT3 levels were associated with a higher risk of GDM after adjustment for potential confounding factors such as age and body mass index (BMI).FT3 and TFQIFT3 were independently associated with the risk of GDM. The results of the present study may shed light on future studies by providing new information on the association of FT3 at the first antenatal visit with GDM.Objective: Thyroid hormones play an important role in the regulation of glucose metabolism. Recently, some studies determined the relationship between diabetes and abnormality of indices of thyroid hormone sensitivity. Thyroid dysfunction may play a role in the etiology of gestational diabetes mellitus (GDM).In the present study, we aim to determine central and peripheral thyroid hormone resistance by evaluating indices of thyroid hormone sensitivity and thyroid function tests and to investigate its effect on the etiology of GDM.A total of 1416 euthyroid pregnant women were included in this study. Of these, 241 (17%) had GDM and 1175 (83%) did not have GDM. We evaluated the association of indices of sensitivity to thyroid hormones including TFQIFT4, TFQIFT3, TSHI, TT4RI, and FT3/FT4, with GDM in pregnant euthyroid women.We found higher FT3, TFQIFT3, and FT3/FT4 ratio in the GDM group. The present study also showed that significantly increased FT3 and TFQIFT3 levels were associated with a higher risk of GDM after adjustment for potential confounding factors such as age and body mass index (BMI).FT3 and TFQIFT3 were independently associated with the risk of GDM. The results of the present study may shed light on future studies by providing new information on the association of FT3 at the first antenatal visit with GDM.Methods: Thyroid hormones play an important role in the regulation of glucose metabolism. Recently, some studies determined the relationship between diabetes and abnormality of indices of thyroid hormone sensitivity. Thyroid dysfunction may play a role in the etiology of gestational diabetes mellitus (GDM).In the present study, we aim to determine central and peripheral thyroid hormone resistance by evaluating indices of thyroid hormone sensitivity and thyroid function tests and to investigate its effect on the etiology of GDM.A total of 1416 euthyroid pregnant women were included in this study. Of these, 241 (17%) had GDM and 1175 (83%) did not have GDM. We evaluated the association of indices of sensitivity to thyroid hormones including TFQIFT4, TFQIFT3, TSHI, TT4RI, and FT3/FT4, with GDM in pregnant euthyroid women.We found higher FT3, TFQIFT3, and FT3/FT4 ratio in the GDM group. The present study also showed that significantly increased FT3 and TFQIFT3 levels were associated with a higher risk of GDM after adjustment for potential confounding factors such as age and body mass index (BMI).FT3 and TFQIFT3 were independently associated with the risk of GDM. The results of the present study may shed light on future studies by providing new information on the association of FT3 at the first antenatal visit with GDM.Results: Thyroid hormones play an important role in the regulation of glucose metabolism. Recently, some studies determined the relationship between diabetes and abnormality of indices of thyroid hormone sensitivity. Thyroid dysfunction may play a role in the etiology of gestational diabetes mellitus (GDM).In the present study, we aim to determine central and peripheral thyroid hormone resistance by evaluating indices of thyroid hormone sensitivity and thyroid function tests and to investigate its effect on the etiology of GDM.A total of 1416 euthyroid pregnant women were included in this study. Of these, 241 (17%) had GDM and 1175 (83%) did not have GDM. We evaluated the association of indices of sensitivity to thyroid hormones including TFQIFT4, TFQIFT3, TSHI, TT4RI, and FT3/FT4, with GDM in pregnant euthyroid women.We found higher FT3, TFQIFT3, and FT3/FT4 ratio in the GDM group. The present study also showed that significantly increased FT3 and TFQIFT3 levels were associated with a higher risk of GDM after adjustment for potential confounding factors such as age and body mass index (BMI).FT3 and TFQIFT3 were independently associated with the risk of GDM. The results of the present study may shed light on future studies by providing new information on the association of FT3 at the first antenatal visit with GDM.Conclusions: Thyroid hormones play an important role in the regulation of glucose metabolism. Recently, some studies determined the relationship between diabetes and abnormality of indices of thyroid hormone sensitivity. Thyroid dysfunction may play a role in the etiology of gestational diabetes mellitus (GDM).In the present study, we aim to determine central and peripheral thyroid hormone resistance by evaluating indices of thyroid hormone sensitivity and thyroid function tests and to investigate its effect on the etiology of GDM.A total of 1416 euthyroid pregnant women were included in this study. Of these, 241 (17%) had GDM and 1175 (83%) did not have GDM. We evaluated the association of indices of sensitivity to thyroid hormones including TFQIFT4, TFQIFT3, TSHI, TT4RI, and FT3/FT4, with GDM in pregnant euthyroid women.We found higher FT3, TFQIFT3, and FT3/FT4 ratio in the GDM group. The present study also showed that significantly increased FT3 and TFQIFT3 levels were associated with a higher risk of GDM after adjustment for potential confounding factors such as age and body mass index (BMI).FT3 and TFQIFT3 were independently associated with the risk of GDM. The results of the present study may shed light on future studies by providing new information on the association of FT3 at the first antenatal visit with GDM. [ABSTRACT FROM AUTHOR]