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1. Reduction in the number of neutrophils in the broncho-alveolar aspirate is associated with worse prognosis in elderly patients with severe COVID-19.

Author

Arifa, Raquel Duque Nascimento, Gonçalves-Pereira, Marcela Helena, Santiago, Luciana, Ravetti, Cecilia Gómez, Vassallo, Paula Frizera, de Fátima Souza Oliveira, Fernanda, de Paula Sabino, Adriano, Teixeira, Mauro Martins, Nobre, Vandack, da Costa Santiago, Helton, and Souza, Daniele G.

Subjects
COVID-19, OLDER patients, COVID-19 pandemic, NEUTROPHILS, PROGNOSIS
Abstract

The blood levels of neutrophils are associated with the severity of COVID -19. However, their role in the pulmonary environment during COVID -19 severity is not clear. Here, we found a decrease in the neutrophil count in BAL (bronchoalveolar lavage) in non-survivors and in older patients (> 60 years). In addition, we have shown that older patients have higher serum concentration of CXCL8 and increased IL-10 expression by neutrophils. [ABSTRACT FROM AUTHOR]

Published
2023
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