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The phenomenological notion of attitude has gained new traction in recent years, as it proliferates beyond its initial distinction between natural and phenomenological attitudes, notably to describe multiple meanings to critique and reflection. In this paper, I present an account of the concept of an ethical attitude in Husserlian phenomenology. First, I argue that the ethical attitude is best understood as a practical orientation toward personal life as a whole: someone strives to become the best possible person through self-reflection, self-variation, the renewal of values and ends, and resolve. Second, I interpret Husserl's accounts of the ethical reduction and the practical neutrality modification through the notion of the ethical attitude. This allows me to elaborate on questions of motivation for striving to be a good person, even if the world seems inhospitable to that effort. The question of the motivation for the ethical attitude reveals that Husserl grappled with existential and theological issues, including the valuelessness of existence, the problem of contingency, and the idea of God. Ultimately, interpreting Husserl's ethical writings through the notion of the ethical attitude brings together several aspects of his ethics, thereby clarifying the many senses of critique and reflection at play in ethical and social life. [ABSTRACT FROM AUTHOR]

Pinning phenomena for long linear polymers have been studied for a long time. In 2009 Caravenna and Pétrélis (Electron J Probab 14(70):2038–2067, 2009) investigated the effect of a periodic and repulsive multi-interface medium on a (1 + 1) -directed polymer model, when the distance between consecutive interfaces scales with the length of the polymer and with a constant temperature. In this paper, we extend that model and consider weak repulsion, by letting both the temperature and the distance between interfaces scale with the length of the polymer. We obtain a full diagram for this model, showing the behaviour of the polymer depending on the scaling exponents associated to the repulsion and the spacing parameters. When the repulsion is not too weak compared to the interface spacing, we obtain different regimes that extend those obtained by Caravenna and Pétrélis, and either finitely or infinitely many interfaces are visited. When the two exponents match we obtain a diffusive regime with a non-trivial and temperature-dependent diffusion constant. Our key tools include the renewal approach used in the original paper as well as new sharp results on the simple random walk evolving between interfaces. [ABSTRACT FROM AUTHOR]

Laboratory models of renewal are critical for understanding this form of behavioral relapse and informing clinical practice to reduce the occurrence of relapse and facilitate the maintenance of treatment gains. Nonsequential renewal is a modified procedure developed by (Sullivan et al. Journal of the Experimental Analysis of Behavior, 110(1), 74–86 2018) that provides an arrangement to study operant renewal in a manner more consistent with clients receiving clinical services, which involves exposing subjects to treatment and baseline conditions across two or more contexts. Experiment 1 replicated the procedure of (Craig et al. Journal of the Experimental Analysis of Behavior, 112(2), 210–223 2019) to compare ABA renewal of target responding in rats exposed to the nonsequential or sequential renewal procedure. Experiment 2 investigated the use of an olfactory extinction cue in mitigating renewal. In Experiment 1, the Nonsequential Group displayed a greater magnitude of renewal compared to the Sequential Group, consistent with the findings from (Craig et al. Journal of the Experimental Analysis of Behavior, 110(1), 74–86 2019) but inconsistent with those from (Sullivan et al. Journal of the Experimental Analysis of Behavior, 110(1), 74–86 2018) with human participants. The extinction cue did not mitigate renewal in Experiment 2. The use of a laboratory model of renewal that is more analogous to clinical settings may be valuable in a translational approach to investigating relapse-prevention techniques. [ABSTRACT FROM AUTHOR]

Renewal is the return of extinguished responding after removal from the extinction context. Renewal has been extensively studied using classical aversive conditioning procedures that measure a passive freezing response to an aversive conditioned stimulus. However, coping responses to aversive stimuli are complex and can be reflected in passive and active behaviours. Using the shock-probe defensive burying task, we investigated whether different coping responses are susceptible to renewal. During conditioning, male, Long-Evans rats were placed into a specific context (Context A) where an electrified shock-probe delivered a 3 mA shock upon contact. During extinction, the shock-probe was unarmed in either the same (Context A) or a different context (Context B). Renewal of conditioned responses was assessed in the conditioning context (ABA) or in a novel context (ABC or AAB). Renewal of passive coping responses, indicated by an increased latency and a decreased duration of shock-probe contacts, was observed in all groups. However, renewal of passive coping, measured by increased time spent on the side of the chamber opposite the shock-probe, was only found in the ABA group. Renewal of active coping responses linked to defensive burying was not observed in any group. The present findings highlight the presence of multiple psychological processes underlying even basic forms of aversive conditioning and demonstrate the importance of assessing a broader set of behaviours to tease apart these different underlying mechanisms. The current findings suggest that passive coping responses may be more reliable indicators for assessing renewal than active coping behaviours associated with defensive burying. [ABSTRACT FROM AUTHOR]

Punishment and extinction are both effective methods of reducing instrumental responding and may involve similar learning mechanisms. To characterize the similarities and differences between them, we examined three well-established recovery or "relapse" effects –renewal, spontaneous recovery, and reacquisition – following either punishment or extinction of an instrumental response. In Experiment 1a, both punished and extinguished responses renewed to similar degrees following a context change at test (ABA renewal). In Experiment 1b, responding spontaneously recovered to similar degrees following punishment or extinction. In Experiment 2, responding was rapidly reacquired when the response was reinforced again following extinction but not following punishment, as predicted by the idea that the reinforcer delivered in reacquisition is part of the context of punishment, but not extinction. The results collectively suggest that both punishment and extinction produce similar context-dependent retroactive interference effects. More broadly, they also suggest that punished and extinguished responses may be equally likely to return following a change of context despite the intuition that punishment might provide a more extreme and effective means of suppressing behavior. To our knowledge, this is the first direct behavioral comparison of response recovery after punishment and extinction within individual experiments. [ABSTRACT FROM AUTHOR]

According to Husserl's self-description, his phenomenological project was "completely apolitical." Husserl's phenomenology did not provide a political philosophy in the classical sense, a normative description of a functioning social order and its respective institutional structures. Nor did Husserl have much to say about the day-to-day politics of his time. Yet his reflections on community and culture were not completely without political implications. This article deals with an often-neglected strand of Husserl's philosophy, namely his critique of liberalism. In this article, liberalism is understood in the manner of Leo Strauss, as a tradition of individualist philosophy emerging from Hobbes's political thought. As the article shows, Husserl followed many of his contemporaries in criticizing Hobbes's abstract individualism, which could provide only a preventative function for political institutions. More importantly, Husserl's engagement with Hobbes can be understood as a kind of ethical counterpart to his analysis of Galileo in the Crisis, as a critique of formal apriorism in the political domain. What Galileo did for physical nature with his "garb of ideas," Hobbes did for human nature, reducing human sociality to interactions between atomistic individuals. In doing so, Hobbes ended up presenting a "mathematics of sociality" in an empirical garb. Going against the liberal view of the human person, Husserl presented his theory of social ethics founded on an original co-existence of subjects and a theory of human renewal. [ABSTRACT FROM AUTHOR]

Rationale: Alcohol use is reliably preceded by discrete and contextual stimuli which, through diverse learning processes, acquire the capacity to promote alcohol use and relapse to alcohol use. Objective: We review contemporary extinction, renewal, reinstatement, occasion setting, and sex differences research within a conditioning framework of relapse to alcohol use to inform the development of behavioural and pharmacological therapies. Key findings: Diverse learning processes and corresponding neurobiological substrates contribute to relapse to alcohol use. Results from animal models indicate that cortical, thalamic, accumbal, hypothalamic, mesolimbic, glutamatergic, opioidergic, and dopaminergic circuitries contribute to alcohol relapse through separable learning processes. Behavioural therapies could be improved by increasing the endurance and generalizability of extinction learning and should incorporate whether discrete cues and contexts influence behaviour through direct excitatory conditioning or occasion setting mechanisms. The types of learning processes that most effectively influence responding for alcohol differ in female and male rats. Conclusion: Sophisticated conditioning experiments suggest that diverse learning processes are mediated by distinct neural circuits and contribute to relapse to alcohol use. These experiments also suggest that gender-specific behavioural and pharmacological interventions are a way towards efficacious therapies to prevent relapse to alcohol use. [ABSTRACT FROM AUTHOR]

Renewal refers to the relapse of a previously reduced response following a context change, and the occurrence of renewal is often countertherapeutic in clinical settings. In the extant literature, renewal has most often been studied following response suppression by extinction or differential reinforcement of alternative behavior. We conducted two human-operant experiments to evaluate ABA and ABC renewal following the suppression of a response by a fixed-time (FT) schedule of point delivery (commonly referred to as noncontingent reinforcement in clinical settings). During baseline, clicking on a moving circle was reinforced with one point according to a random-interval (RI) 5-s schedule in context A. During the FT phase, one point was delivered every 5 s in context B. In the renewal test phase, the FT 5-s schedule remained, and the background color of the screen returned to the baseline context (ABA renewal; Experiment 1) or changed to a third, novel context (ABC renewal; Experiment 2). We investigated within-subject repeatability of renewal using a six-phase reversal design. Renewal occurred in the first iteration of the three-phase arrangement for 11 of 12 participants. ABA renewal was repeated for two of six participants and occurred in the second iteration only for one participant. ABC renewal was repeated for five of six participants. These results extend the literature by demonstrating renewal of responses, previously decreased using FT schedules, following the reintroduction of a previous context or the presentation of a new context. Future research should investigate the occurrence and mitigation of renewal during time-based schedules. [ABSTRACT FROM AUTHOR]

Individuals who engage in problem behavior receive treatment services in various settings, such as their homes, schools, and clinics. These individuals are also likely to experience treatment provision from various practitioners, such as therapists, teachers, and caregivers. Changes in the treatment setting or intervention agent (i.e., context) can cause renewal of problem behavior. Renewal is the form of relapse that occurs when a previously eliminated behavior returns due to a change in context. Practitioners should know six things about renewal to improve clinical practice: (1) generality of renewal; (2) potential for renewal even when alternative reinforcement is available; (3) similarity between renewal testing procedures and situations that practitioners commonly encounter; (4) close relationship between renewal and the generalization of behavior change; (5) distinction between renewal and another form of relapse (i.e., resurgence); and (6) potential mitigation strategies. Practitioners should prepare for renewal during context changes when working with their clients, especially during changes to the treatment setting or intervention agent. [ABSTRACT FROM AUTHOR]

Renewal is one form of behavioral relapse in which a previously reduced response reemerges following a contextual change. Renewal is prevalent during clinical interventions and can result in countertherapeutic increases in undesired behavior. We evaluated renewal during ongoing omission training using a remote human-operant arrangement. Participants responded by clicking on a rectangle, and the context during each of the three phases was represented by the background color of the computer program. During the baseline phase, points were delivered contingent on target responding in Context A. During the omission-training phase, points were delivered according to a differential reinforcement of other behavior (DRO) schedule in Context B. During the renewal-test phase, the DRO schedule remained in place, and the context either returned to Context A (Experiment 1; ABA renewal) or to a novel Context C (Experiment 2; ABC renewal). Renewal occurred for 24 of 25 participants across both experiments. To evaluate the repeatability of renewal, some participants in each experiment completed the three-phase renewal sequence twice. ABA renewal was replicated across iterations for three of five participants, and ABC renewal was replicated for one of four participants. The results of this translational investigation suggest that practitioners employing omission training should be aware of potential renewal following context changes, even when the DRO contingency remains unchanged. Future research should evaluate techniques for mitigating renewal during omission training. [ABSTRACT FROM AUTHOR]

Rationale: Several single or combined therapeutic approaches have been developed to treat addiction, however with partial efficacy in preventing relapse. Recently, the living environment has been suggested as a critical intervening factor determining the treatment outcomes. Despite accumulating evidence confirming a role of living conditions in the vulnerability to addictive behaviours, their impact on single or integrative therapeutic strategies preventing relapse is yet to be identified. Objectives: Here, we explore the possible interaction between brief Environmental Enrichment (EE) exposure and acute fluoxetine administration in inhibiting sucrose-seeking behaviours, and whether this effect could be affected by living environment. Methods: Social and isolated adult male C57BL/6 mice were trained to sucrose self-administration associated to a specific conditioning context (CxA), followed by a 7-day extinction in a different context (CxB). Afterwards, mice were exposed for 22 h to EE and then injected with fluoxetine (10 mg/kg, i.p.) 1 h before a CxA-induced sucrose-seeking test. Results: Brief EE exposure and acute fluoxetine administration alone inhibited context-induced sucrose-seeking in both housing conditions; however, they exhibited additive properties only in social condition. Conclusions: Our data show that social environment may influence the EE/fluoxetine interaction in inhibiting relapse to sucrose. These findings suggest that setting up proper living conditions to boost the efficacy of therapeutic approaches may represent a fundamental strategy to treat addiction disorders. [ABSTRACT FROM AUTHOR]

Recovery-from-extinction effects in which a conditioned response returns after extinction have been shown in mammals, birds and fish. Thus, these effects appear to be conserved among vertebrates; however, they have yet to be investigated in amphibians. Using prey catching conditioning in the fire-bellied toad (Bombina orientalis), we tested if renewal and reinstatement occurred after extinction when subjects were respectively re-exposed to the context or reinforcer used during conditioning. For renewal, a different context was used during extinction and thus renewal tests assessed if external contextual cues associated during conditioning stimulated prey catching performance. For reinstatement, the reinforcer withheld during extinction was simply delivered again prior to a test assessing if internal cues associated with recent prey consumption stimulated prey catching performance. Conditioning followed a fixed ratio 5 schedule of reinforcement, where five attempts to capture a cricket stimulus displayed on a computer screen were reinforced by delivery of a single live cricket. Performance was measured as the time to reach five prey catching attempts. A significant improvement in prey catching performance during conditioning followed by deterioration with extinction was seen in the experiments. Upon return to the context used for conditioning after extinction, toads showed a renewal effect whereby they displayed faster performance during testing compared to the end of extinction. Conversely, toads showed no reinstatement effect because pre-feeding of a cricket did not influence performance during the test that followed extinction. Reinstatement could have been lost in amphibian phylogeny due to secondary simplification of the nervous system. [ABSTRACT FROM AUTHOR]

The present free operant conditioning experiments with rats examined the impact of manipulating different traits of an extinction-cue on ABA renewal. All rats were trained to perform an operant response (R1) for food in context A, and a different operant response (R2) in context B. Responses were then extinguished, R1 in context B and R2 in context A. In Experiment 1, for half of the rats, both responses were extinguished in the presence of an intermittent light. For the other half, a continuous light was utilized during extinction of R1 and R2. Finally, all rats were tested in both contexts (R1 was tested in the presence of the cue in both contexts, whereas R2 was tested in the presence of the cue only in the extinction context). Returning the rats to the original conditioning context renewed the initial operant behavior. However, we found that both types of extinction-cues (intermittent and continuous) attenuated ABA renewal equally. In addition, both responses underwent extinction in Experiment 2. For half of the subjects, R1 and R2 were extinguished in the presence of a dim light, whereas the other half received a bright light as an extinction-cue for both responses. Once again, we found during testing (R1 was tested in the presence of the cue in both contexts whereas R2 was tested in the presence of the cue only in the extinction context), that both types of extinction-cues reduced ABA renewal in a similar manner. The present results suggest that in some conditions, the features of the extinction cues may not affect their renewal-attenuating properties. [ABSTRACT FROM AUTHOR]

This paper responds to calls for renewal in Islamic schooling and education. In doing so, it provides insight into educators' views on Islamic Studies (IS) in five Australian Islamic schools, with a focus on senior years (years 10, 11 and 12). The study offers a 'dialogic alternative' of 'speaking with' rather than 'speaking for' educators in Islamic educational research, planning, and renewal within K-12 Australian Islamic schools. It privileges educators' voice and enables an insight into their experience with one of the most important and distinct features of Islamic schools – IS. Using phenomenology as a methodological framework, educators' voice was elicited through focus groups where eighteen educators provided information describing their experience with IS. The study identified "strengths" and "challenges" of IS. Strengths includes parents' desire for IS, educators' personal connection with learner, knowledge of subject-matter, autonomy in teaching IS and unity among IS educators. The challenges outweigh the strengths and include insufficient time for IS, lack of resources, absence of a clear vision leading to a tokenistic and fragmented approach to the teaching of IS, low-level respect and recognition of IS educators and more. [ABSTRACT FROM AUTHOR]

Medicaid beneficiaries in most states must go through a redetermination process every 6–12 months to demonstrate continued eligibility. This study sought to examine Medicaid redetermination experiences among beneficiaries with Limited English Proficiency (LEP). A sequential mixed methods study was conducted involving quantitative phone surveys and semi-structured, in-person interviews with Arabic, Chinese, Korean, and Vietnamese speaking beneficiaries in Illinois. Survey respondents experienced notable barriers during the redetermination process. Quantitative data showed LEP respondents to have 5.3 times the odds of losing their Medicaid benefits as compared to English proficient respondents. Qualitative interviews illustrated the impact of Medicaid loss on individuals and families, as well as strategies for successfully navigating redetermination. Findings suggest that language barriers hinder Medicaid redetermination and play a role in cancellation of benefits. Recommendations for better language supports during the Medicaid redetermination process are discussed. [ABSTRACT FROM AUTHOR]

In the midst of the global Covid-19 pandemic, educators are invited to pause and reconsider the legacies this crisis will leave for future generations. What lessons do we take forward in a post-Covid-19 curriculum? This article contemplates the value of Indigenous resilience, innovation, and adaptation in times of crisis—"In(di)genuity", if you will—and considers its implications on Indigenous knowledge and the curricular discourse more broadly. Despite encouraging developments in Indigenous education since the Truth and Reconciliation Commission, a settler historical consciousness continues to pervade the modern discourse of Indigenous education, insofar as Indigenous knowledge is often perceived as outdated, irrelevant, or inferior to Western knowledge systems. This problematic misconception ignores the resilience, innovation, and adaptation that Indigenous peoples have demonstrated in the face of historical crises. This article offers an Indigenous perspective on crisis, grief, and renewal in the context of Covid-19 and advocates for the renewal of the Canadian curricular landscape. [ABSTRACT FROM AUTHOR]

The biomorphological features of Hydrilla verticillata (L. fil.) Royle in tropical and temperate regions of the Eurasian part of the geographical range have been studied. The shoot system is long-growing and sympodial, consisting of (annual)oligoennial monopodial shoots of main and subordinate orders. The number of leaves per node; shape, length, and width of leaf blade; branching peculiarities; and the length of the internode are the most variable signs. Hydrilla verticillata is a perennial (vegetatively oligoennial) polycarpic rooting long-shoot high turion-tuber vegetative–mobile hydrophyte. The flexibility of biomorphs in different biotypes is manifested by the duration of shoot ontogenesis and by a change in the ratio of the specialized vegetative diasporas. Turions and tubers are the two alternative models for maintaining the population. [ABSTRACT FROM AUTHOR]

Renewal is a phenomenon in which a response that has been extinguished recovers when an organism is removed from the setting in which extinction occurred. In most renewal studies, context consists of exteroceptive stimuli (e.g., distinct visual, auditory, tactile, and/or olfactory stimuli). Nevertheless, a number of studies have shown that interoceptive stimuli such as those induced by drugs or food deprivation may come to exert discriminative control over behavior under the relevant contingencies. We investigated how interoceptive organismic conditions brought about through food deprivation and satiation motivating operations (MOs) can serve as contextual cues for the renewal of extinguished operant responding in mice. Three groups of mice received acquisition and extinction sessions under three different combinations of food deprivation and satiation. One group received acquisition sessions while deprived and extinction sessions while satiated. A second group received both acquisition and extinction sessions while satiated. A third group received both acquisition and extinction sessions while deprived. All groups were then tested for renewal under both deprivation and satiation conditions. ABA and AAB renewal were observed for the first two groups under deprivation conditions, but AAB renewal was not observed for the third group under satiation conditions. The results suggest that interoceptive stimuli elicited by MOs may serve as contextual stimuli that occasion the recovery of responding following extinction, but unlike exteroceptive contextual cues, the discriminative functions of these stimuli are accompanied by motivational functions that may affect the extent to which renewal is observed. [ABSTRACT FROM AUTHOR]

We investigate the global dynamics of a general Kermack–McKendrick-type epidemic model formulated in terms of a system of renewal equations. Specifically, we consider a renewal model for which both the force of infection and the infected removal rates are arbitrary functions of the infection age, τ , and use the direct Lyapunov method to establish the global asymptotic stability of the equilibrium solutions. In particular, we show that the basic reproduction number, R 0 , represents a sharp threshold parameter such that for R 0 ≤ 1 , the infection-free equilibrium is globally asymptotically stable; whereas the endemic equilibrium becomes globally asymptotically stable when R 0 > 1 , i.e. when it exists. [ABSTRACT FROM AUTHOR]

Extinction of conditioned aversive responses (CR) has been shown to be context-dependent. The hippocampus and prefrontal cortex are of particular importance. The cerebellum may contribute to context-related processes because of its known connections with the hippocampus and prefrontal cortex. Context dependency of extinction can be demonstrated by the renewal effect. When CR acquisition takes place in context A and is extinguished in context B, renewal refers to the recovery of the CR in context A (A-B-A paradigm). In the present study acquisition, extinction and renewal of classically conditioned eyeblink responses were tested in 18 patients with subacute focal cerebellar lesions and 18 age- and sex-matched healthy controls. Standard delay eyeblink conditioning was performed using an A-B-A paradigm. All cerebellar patients underwent a high-resolution T1-weighted brain MRI scan to perform lesion-symptom mapping. CR acquisition was not significantly different between cerebellar and control participants allowing to draw conclusions on extinction. CR extinction was significantly less in cerebellar patients. Reduction of CR extinction tended to be more likely in patients with lesions in the lateral parts of lobule VI and Crus I. A significant renewal effect was present in controls only. The present data provide further evidence that the cerebellum contributes to extinction of conditioned eyeblink responses. Because acquisition was preserved and extinction took place in another context than acquisition, more lateral parts of the cerebellar hemisphere may contribute to context-related processes. Furthermore, lack of renewal in cerebellar patients suggest a contribution of the cerebellum to context-related processes. [ABSTRACT FROM AUTHOR]

In the recent decade, fear conditioning has evolved as a standard procedure for testing cognitive abilities such as memory acquisition, consolidation, recall, reconsolidation, and extinction, preferentially in genetically modified mice. The reasons for the popularity of this powerful approach are its ease to perform, the short duration of training and testing, and its well-described neural basis. So why to bother about flaws in standardization of test procedures and analytical routines? Simplicity does not preclude the existence of fallacies. A short survey of the literature revealed an indifferent use of acoustic stimuli in terms of quality (i.e., white noise vs. sine wave), duration, and intensity. The same applies to the shock procedures. In the present article, I will provide evidence for the importance of qualitative and quantitative parameters of conditioned and unconditioned stimuli for the experimental outcome. Moreover, I will challenge frequently applied interpretations of short-term vs. long-term extinction and spontaneous recovery. On the basis of these concerns, I suggest a guideline for standardization of fear conditioning experiments in mice to improve the comparability of the experimental data. [ABSTRACT FROM AUTHOR]

This paper takes the so-called probabilistic approach to the strong renewal theorem (SRT) for multivariate distributions in the domain of attraction of a stable law. A version of the SRT is obtained that allows any kind of lattice-nonlattice composition of a distribution. A general bound is derived to control the so-called small-n contribution, which arises from random walk paths that have a relatively small number of steps but make large cumulative moves. The asymptotic negligibility of the small-n contribution is essential to the SRT. Applications of the SRT are given, including some that provide a unified treatment to known results but with substantially weaker assumptions. [ABSTRACT FROM AUTHOR]

Morphological variation based on eight measured and four derived traits was studied to establish whether there was significant variation between populations and to identify the influence of the altitude on morphological differentiation among 44 natural stands of common oak (Quercus robur L.) in Bosnia and Herzegovina, ranging from 82 to 860 m. The results point to significant intra- and inter-population differences. Elevation-related variation is less pronounced and determined largely by microclimatic factors. The results could provide management strategies for species reintroduction in the study area. There are no differences in leaf morphology between the different branches of individual trees. However, there are important variations between the altitudinal groups and closely linked to environmental factors in all traits. An important recommendation is to use seeds from oak with attention to their altitudinal origin. [ABSTRACT FROM AUTHOR]

Rationale: Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli.This study determined if renewal of cocaine seeking is differentially controlled using a context consisting of either a social peer and/or house light illumination.In Experiment 1, male and female rats trained to self-administer cocaine in the presence of a same-sex social peer and house light illumination (context A). Following self-administration, rats were randomly assigned to either an AAA (control) or ABA (renewal) group for extinction. For AAA rats, extinction consisted of the same context A as self-administration; for ABA rats, extinction occurred without the peer or house light (context B). Following extinction, renewal of cocaine seeking occurred by testing the peer alone, house light alone, and the peer + house light combination. Experiment 2 was conducted to ensure that the house light alone was sufficiently salient to produce renewal.Both experiments showed that rats acquired cocaine self-administration and extinguished lever pressing. In Experiment 1, the ABA group renewed cocaine seeking to the peer and peer + house light, but not to the house light alone. In Experiment 2, ABA rats renewed cocaine seeking to the house light alone, indicating it was sufficiently salient to produce renewal. The AAA group did not show renewal in either experiment.Social peers serve as powerful stimuli that can overshadow nonsocial visual stimuli in the renewal of cocaine seeking.Objectives: Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli.This study determined if renewal of cocaine seeking is differentially controlled using a context consisting of either a social peer and/or house light illumination.In Experiment 1, male and female rats trained to self-administer cocaine in the presence of a same-sex social peer and house light illumination (context A). Following self-administration, rats were randomly assigned to either an AAA (control) or ABA (renewal) group for extinction. For AAA rats, extinction consisted of the same context A as self-administration; for ABA rats, extinction occurred without the peer or house light (context B). Following extinction, renewal of cocaine seeking occurred by testing the peer alone, house light alone, and the peer + house light combination. Experiment 2 was conducted to ensure that the house light alone was sufficiently salient to produce renewal.Both experiments showed that rats acquired cocaine self-administration and extinguished lever pressing. In Experiment 1, the ABA group renewed cocaine seeking to the peer and peer + house light, but not to the house light alone. In Experiment 2, ABA rats renewed cocaine seeking to the house light alone, indicating it was sufficiently salient to produce renewal. The AAA group did not show renewal in either experiment.Social peers serve as powerful stimuli that can overshadow nonsocial visual stimuli in the renewal of cocaine seeking.Methods: Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli.This study determined if renewal of cocaine seeking is differentially controlled using a context consisting of either a social peer and/or house light illumination.In Experiment 1, male and female rats trained to self-administer cocaine in the presence of a same-sex social peer and house light illumination (context A). Following self-administration, rats were randomly assigned to either an AAA (control) or ABA (renewal) group for extinction. For AAA rats, extinction consisted of the same context A as self-administration; for ABA rats, extinction occurred without the peer or house light (context B). Following extinction, renewal of cocaine seeking occurred by testing the peer alone, house light alone, and the peer + house light combination. Experiment 2 was conducted to ensure that the house light alone was sufficiently salient to produce renewal.Both experiments showed that rats acquired cocaine self-administration and extinguished lever pressing. In Experiment 1, the ABA group renewed cocaine seeking to the peer and peer + house light, but not to the house light alone. In Experiment 2, ABA rats renewed cocaine seeking to the house light alone, indicating it was sufficiently salient to produce renewal. The AAA group did not show renewal in either experiment.Social peers serve as powerful stimuli that can overshadow nonsocial visual stimuli in the renewal of cocaine seeking.Results: Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli.This study determined if renewal of cocaine seeking is differentially controlled using a context consisting of either a social peer and/or house light illumination.In Experiment 1, male and female rats trained to self-administer cocaine in the presence of a same-sex social peer and house light illumination (context A). Following self-administration, rats were randomly assigned to either an AAA (control) or ABA (renewal) group for extinction. For AAA rats, extinction consisted of the same context A as self-administration; for ABA rats, extinction occurred without the peer or house light (context B). Following extinction, renewal of cocaine seeking occurred by testing the peer alone, house light alone, and the peer + house light combination. Experiment 2 was conducted to ensure that the house light alone was sufficiently salient to produce renewal.Both experiments showed that rats acquired cocaine self-administration and extinguished lever pressing. In Experiment 1, the ABA group renewed cocaine seeking to the peer and peer + house light, but not to the house light alone. In Experiment 2, ABA rats renewed cocaine seeking to the house light alone, indicating it was sufficiently salient to produce renewal. The AAA group did not show renewal in either experiment.Social peers serve as powerful stimuli that can overshadow nonsocial visual stimuli in the renewal of cocaine seeking.Conclusion: Various nonsocial cues have been used as stimuli to examine the contextual control of drug seeking behavior, but little is known about the role of social stimuli.This study determined if renewal of cocaine seeking is differentially controlled using a context consisting of either a social peer and/or house light illumination.In Experiment 1, male and female rats trained to self-administer cocaine in the presence of a same-sex social peer and house light illumination (context A). Following self-administration, rats were randomly assigned to either an AAA (control) or ABA (renewal) group for extinction. For AAA rats, extinction consisted of the same context A as self-administration; for ABA rats, extinction occurred without the peer or house light (context B). Following extinction, renewal of cocaine seeking occurred by testing the peer alone, house light alone, and the peer + house light combination. Experiment 2 was conducted to ensure that the house light alone was sufficiently salient to produce renewal.Both experiments showed that rats acquired cocaine self-administration and extinguished lever pressing. In Experiment 1, the ABA group renewed cocaine seeking to the peer and peer + house light, but not to the house light alone. In Experiment 2, ABA rats renewed cocaine seeking to the house light alone, indicating it was sufficiently salient to produce renewal. The AAA group did not show renewal in either experiment.Social peers serve as powerful stimuli that can overshadow nonsocial visual stimuli in the renewal of cocaine seeking. [ABSTRACT FROM AUTHOR]

Purpose: As a social protection policy, Ghana's National Health Insurance Scheme (NHIS) aims to improve access to healthcare, especially for the vulnerable. Migrant female head porters ( kayayoo), who are part of the informal economic workforce, are underscored as an ethnic minority and vulnerable group in Ghana. This study aimed to analyse the factors associated with enrolment in and renewal and utilisation of the NHIS among migrant female head porters in the Kumasi Metropolis. Method: We purposively sampled 392 migrant female head porters in the Kejetia, Asafo and Bantama markets. We used a binary logit regression model to estimate associations among baseline characteristics, convenience and benefit factors and enrolment in and renewal and utilisation of the NHIS. Result: Age and income significantly increased the probability of NHIS enrolment, renewal and utilisation. Long waiting times at NHIS offices significantly reduced the likelihood of renewal, while provision of drugs highly significantly increased the tendency for migrant female head porters to enrol in, renew and use the NHIS. Consulting and surgery also significantly increased renewal and utilisation of the NHIS. Conclusion: Political commitment is imperative for effective implementation of the decentralisation policy of the NHIS through the National Health Insurance Authority in Kumasi. We argue that retail offices should be well equipped with logistic facilities to ensure convenience in NHIS initial enrolment and renewal processes by citizenry, and by vulnerable groups in particular. [ABSTRACT FROM AUTHOR]

Context-related extinction learning and renewal in humans is mediated by hippocampal and prefrontal regions. Renewal is defined as the reoccurrence of an extinguished response if the contexts present during extinction learning and recall differ. Animal studies implicate hippocampal γ-aminobutyric acid (GABA) A receptors in extinction and renewal. However, human studies on GABAergic mechanisms in extinction learning are lacking. In this fMRI study, we therefore investigated the role of the GABAergic system in context-related extinction learning and renewal. Participants treated with the GABA A agonist lorazepam prior to extinction learning were impaired in encoding changed associations during extinction learning, regardless of context, and in retrieving extinction associations during recall. In contrast, retrieval of associations learned during acquisition was largely unaffected, which led to reduced genuine renewal, since acquisition associations were retrieved context-independently. These deficits, which were presumably due to weak encoding of extinction associations, were related to altered BOLD activation in regions relevant for context processing and retrieval, as well as response selection: reduced activation in bilateral PFC and hippocampus during extinction learning and recall, and increased ventromedial/orbitofrontal cortex activation during recall. Our findings indicate that the GABergic system is involved in context-related extinction learning and recall in humans, by modulating hippocampus-based context processing and PFC-based processing of changed associations and subsequent response selection. [ABSTRACT FROM AUTHOR]

This paper presents an approach proposed for assessing economic performance of retrofit applications performed at functional building element level in residential buildings and exemplifies it for the city of Istanbul, which has a temperate-humid climate. This approach covers three steps. In the first step, typical buildings and their properties are determined by analysing the residential buildings in Istanbul, and then the retrofit alternatives are generated. In the second step, an economic impact analysis is performed for typical buildings by considering the costs during their life cycle phases. In the third step, a life cycle cost assessment is done according to the variables, which are defined as window-to-wall ratio (WWR), window system, thermal insulation material, orientation and building age. The most beneficial retrofits are lastly determined depending on their economic performance ratios (EPRs). In conclusion, insulating exterior wall, projected floors, floors above unheated space and roof floors separately provide the highest benefits at the age of 30, and the lowest benefits occur at the age of 15 for all WWRs. The highest EPRs are obtained for the WWR of 10% at all ages. The renewal with PVC frame provides benefit while the renewal with wooden frame causes losses. Orientation slightly affects the EPRs. The use of stone wool in the retrofit causes a reduction in the EPRs due to high investment cost of stone wool. When the 20-year-old building which has the WWR of 10% is insulated with extruded polystyrene and renewed with PVC, it provides the highest benefit of about 45%. [ABSTRACT FROM AUTHOR]

Let (ΣP ; σP) be the space of a spacing shifts where P ⊂ N0 = N ∐0{0} and ΣP = {s ∈ {0,1}N0 : si = sj = 1 if |i - j| ∈ P ∐ {0}} and σP the shift map. We will show that ΣP is mixing if and only if it has almost specification property with at least two periodic points. Moreover, we show that if h(σP) = 0, then ΣP is almost specified and if h(σP) > 0 and ΣP is almost specified, then it is weak mixing. Also, some sufficient conditions for a coded ΣP being renewal or uniquely decipherable is given. At last we will show that here are only two conjugacies from a transitive ΣP to a subshift of {0; 1}N0. [ABSTRACT FROM AUTHOR]

Obesity is a non-communicable disease that is associated with an increased risk of heart disease, stroke, diabetes, musculoskeletal disorders, and cancer (WHO, 2016). While there are many ways to treat obesity, approximately 80% of those who attempt a diet or exercise program fail to achieve and/or maintain their weight loss (Wing & Phelan, 2005). This article assesses the problem of obesity and the failure to maintain treatment outcomes through a conceptual analysis of relapse. This includes analyzing not only the behaviors of individuals who are obese, but their surrounding environments. This article includes a discussion of resurgence, renewal, reinstatement, and behavioral momentum theory, which may provide additional information and guidance when creating treatment plans related to obesity and obesity-related disorders. Assessing obesity through a behavior analytic lens of relapse may lead to better adherence and maintenance of obesity treatment programs, but also decrease the burden that obesity and obesity relapse has on the health-care system. [ABSTRACT FROM AUTHOR]

This paper contributes to the emerging literature on reshoring by taking a value-driven enquiry into the renewal of supply chain strategy. It enhances the understanding of the use of reshoring in generating the value demanded by a changing business model. An iconic British high-end clothing brand, Burberry, is the chosen case study to explore the recent move towards reshoring because its changes of leadership, business model and evolving supply chain strategy from 1997 to early 2016 provide a timely and pertinent context. Burberry has continued to realign its business towards a brand-led and customer-centric model along with restoring its corporate heritage and core brand values. The changes in Burberry's business model triggered the need to renew and realign its supply chain strategy through consolidating and rebuilding manufacturing activities back in the UK, in order to support its brand repositioning as quintessentially British and the company's refocus on heritage products. The increased managerial control in the supply chain together with the close proximity of design and manufacture enables the promise of quality and brand provenance to be fulfilled. The renewal of Burberry's supply chain strategy has contributed to an increase in revenues and brand values. These findings suggest that the renewal of supply chain strategy through reshoring and increasing control in supply chain operations can enhance value and firm competitiveness. [ABSTRACT FROM AUTHOR]

University students partitioned in four groups were treated to a four-phase resurgence preparation in which three response sequences were sequentially acquired in the first three phases and tested for serial positioning effects and response variability in terminal resurgence phase. For the three test groups, three colored backgrounds served as the contextual stimuli that corresponded to the acquisition of the response sequences in the initial three phases. In the final resurgence phase, all response sequences were placed on extinction. The three test groups were re-presented a respective colored background found in one of the earlier acquisition phases. The fourth group did not involve any colored background throughout the entire experiment. Across all three test groups, the highest acquired response sequence proportion was correlated with the discriminative stimulus present in the resurgence phase. The no-color group without contextual change across phases showed recency and primacy effects consistent with those found in serial position studies. Moreover, the presence of the discriminative stimulus in the resurgence phase resulted in less variable response sequences relative to the no-color group. These findings support the role of discriminative stimuli in the manner with which response patterns are organized in resurgence. [ABSTRACT FROM AUTHOR]

In two human predictive-learning experiments, we investigated the effects of extinction in multiple contexts on the rate of extinction and the strength of response recovery. In each experiment, participants initially received acquisition training with a target cue in one context, followed by extinction either in a different context (extinction in a single context) or in three different contexts (extinction in multiple contexts). The results of both experiments showed that conducting extinction in multiple contexts led to higher levels of responding during extinction than did extinction in a single context. Additionally, Experiment 2 showed that extinction in multiple contexts prevented ABC renewal but had no detectable impact on ABA renewal. Our results are discussed within the framework of contemporary learning theories of contextual control and extinction. [ABSTRACT FROM AUTHOR]

Previous research on the resurgence effect has suggested that reinforcers that are presented during the extinction of an operant behavior can control inhibition of the response. To further test this hypothesis, in three experiments with rat subjects we examined the effectiveness of using reinforcers that were presented during extinction as a means of attenuating or inhibiting the operant renewal effect. In Experiment 1, lever pressing was reinforced in Context A, extinguished in Context B, and then tested in Context A. Renewal of responding that occurred during the final test was attenuated when a distinct reinforcer that had been presented independent of responding during extinction was also presented during the renewal test. Experiment 2 established that this effect depended on the reinforcer being featured as a part of extinction (and thus associated with response inhibition). Experiment 3 then showed that the reinforcers presented during extinction suppressed performance in both the extinction and renewal contexts; the effects of the physical and reinforcer contexts were additive. Together, the results further suggest that reinforcers associated with response inhibition can serve a discriminative role in suppressing behavior and may be an effective stimulus that can attenuate operant relapse. [ABSTRACT FROM AUTHOR]

Context dependency of extinction is well known and has extensively been studied in fear conditioning, but has rarely been assessed in eyeblink conditioning. One way to demonstrate context dependency of extinction is the renewal effect. ABA paradigms are most commonly used to show the renewal effect of extinguished learned fear: if acquisition takes place in context A, and extinction takes place in context B (extinction phase), learned responses will recover in subsequent extinction trials presented in context A (renewal phase). The renewal effect of the visual threat eyeblink response (VTER), a conditioned eyeblink response, which is naturally acquired in early infancy, was examined in a total of 48 young and healthy participants with two experiments using an ABA paradigm. Twenty paired trials were performed in context A (baseline trials), followed by 50 extinction trials in context B (extinction phase) and 50 extinction trials in context A (renewal phase). In 24 participants, contexts A and B were two different rooms, and in the other 24 participants, two different background colors (orange and blue) and noises were used. To rule out spontaneous recovery, an AAA design was used for comparison. There were significant effects of extinction in both experiments. No significant renewal effects were observed. In experiment 2, however, extinction was significantly less using orange background during extinction compared to the blue background. The present findings suggest that extinction of conditioned eyeblinks depends on the physical context. Findings add to the animal literature that context can play a role in the acquisition of classically conditioned eyeblink responses. Future studies, however, need to be performed to confirm the present findings. Lack of renewal effect may be explained by the highly overlearned character of the VTER. [ABSTRACT FROM AUTHOR]

Exposure to a cue alone either before (i.e., latent inhibition treatment) or after (i.e., extinction) the cue is paired with an unconditioned stimulus results in attenuated conditioned responding to the cue. Here we report two experiments in which potential parallels between the context specificity of the effects of extinction and latent inhibition treatments were directly compared in a lick suppression preparation with rats. The reversed ordering of conditioning and nonreinforcement in extinction and latent inhibition designs allowed us to examine the effect of training order on the context specificity of what is learned given phasic reinforcement and nonreinforcement of a target cue. Experiment 1 revealed that when conditioned-stimulus (CS) conditioning and CS nonreinforcement were administered in the same context, both extinction and latent inhibition treatments had reduced impacts on test performance, relative to excitatory conditioning when testing occurred outside the treatment context. Similarly, Experiment 2 showed that when conditioning was administered in one context and nonreinforcement was administered in a second context, the effects of both extinction and latent inhibition treatments were attenuated when testing occurred in a neutral context, relative to the context in which the CS was nonreinforced. The observed context specificity of extinction and latent inhibition treatments has been previously reported in both cases, but not in a single experiment under otherwise identical conditions. The results of the two experiments convergently suggest that memory of nonreinforcement becomes context dependent after a cue is both reinforced and nonreinforced, independent of the order of training. [ABSTRACT FROM AUTHOR]

This paper investigates a firm's decisions regarding renewal and patenting of sequential inventions and tests the implications of a dynamic model of patent portfolio management where a firm makes the decisions taking into account complementarity and substitutability across sequential inventions. We use cross-price effects of renewal fees and filing fees on renewal and patenting decisions to identify complementarity or substitutability. We find that higher filing fees are associated with a lower probability of patent renewal, which supports the idea of complementarity across sequential inventions. [ABSTRACT FROM AUTHOR]

The Attentional Theory of Context Processing (ATCP) states that extinction will arouse attention to contexts resulting in learning becoming contextually controlled. Participants learned to suppress responding to colored sensors in a video-game task where contexts were provided by different gameplay backgrounds. Four experiments assessed the contextual control of simple excitatory learning acquired to a test stimulus (T) after (Exp. 1) or during (Exp. 2-4) extinction of another stimulus (X). Experiment 1 produced no evidence of contextual control of T, though renewal to X was present both at the time T was trained and tested. In Experiment 2 no contextual control of T was evident when X underwent extensive conditioning and extinction. In Experiment 3 no contextual control of T was evident after extensive conditioning and extinction of X, and renewal to X was present. In Experiment 4 contextual control was evident to T, but it neither depended upon nor was enhanced by extinction of X. The results presented here appear to limit the generality of ATCP. [ABSTRACT FROM AUTHOR]

Within the EU regulatory framework, licensees for commercial radio broadcasting may be charged a fee to ensure optimal allocation of scarce resources but not to maximize public revenues. While radio licence renewal occurs in many EU countries, an objective, model-based approach for setting licence fees has not been used so far. In this paper, it is described how such a fee can be determined for the purpose of licence renewal or extension. National and regional Dutch FM licences were valued, taking into account that simulcast broadcasting of digital and analogue radio is obligatory upon extension. Licences are valued using discounted cash flow methodology, whereby the cash flows of an averagely efficient entrant are taken as the benchmark for valuation of each individual licence. Cash flows during the licence period 2011-2017 are forecast based on generalized least squares regressions, using financial variables of Dutch radio stations for the years 2004-2008. Separately, bottom-up cost and investment models are used to calculate analogue and digital distribution costs. This results in a value per licence, based on objective licence characteristics, which can be used to set licence fees if administrative renewal or extension is opted for instead of a new auction or beauty contest. [ABSTRACT FROM AUTHOR]

Retroactive cue interference refers to situations in which a target cue X is paired with an outcome in phase 1 and a nontarget cue Z is paired with the same outcome in phase 2, with less subsequent responding to X being seen as a result of the phase 2 training. Two conditioned suppression experiments with rats were conducted to determine whether retroactive cue interference is similarly modulated by a manipulation that influences retroactive outcome interference (e.g., extinction). Both experiments used an ABC renewal-like design in which phase 1 training, phase 2 training, and testing each occurred in different contexts. Experiment 1 found that training the target association in multiple contexts without altering the number of training trials during phase 1 decreased retroactive cue interference (i.e., increased responding consistent with the target association). Experiment 2 found that training the interfering association in multiple contexts without altering the number of interference trials during phase 2 increased retroactive cue interference (i.e., decreased responding consistent with the target association). The possibility of similar mechanisms underlying cue interference and outcome interference is discussed. [ABSTRACT FROM AUTHOR]

This article presents a 3-D science-fiction-based videogame method to study learning, and two experiments that we used to validate it. In this method, participants are first trained to respond to enemy spaceships (Stimulus 2, or S2) with particular keypresses, followed by transport to a new context (galaxy), where other manipulations can occur. During conditioning, colored flashing lights (Stimulus 1, or S1) can predict S2, and the response attached to S2 from the prior phase comes to be evoked by S1. In Experiment 1 we demonstrated that, in accord with previous findings from animals, conditioning in this procedure was positively related to the ratio of the time between trials to the time within a trial. Experiment 2 demonstrated the phenomena of extinction, timing, and renewal. Responding to S1 was slightly lost with a context change, and diminished over trials in the absence of S2. On early extinction trials, responding during S1 declined after the time that S2 normally occurred. Extinguished responding to S1 recovered robustly with a context change. [ABSTRACT FROM AUTHOR]

Service memberships are commonly used to support consumer relationships, yet the mechanisms for consumers' membership decisions are poorly understood. This paper develops a model of consumers' decision to modify (upgrade or downgrade) a service membership conditional on their decision to renew. Bridging insights from relationship marketing and consumer behavior, the proposed model conceptualizes how relational drivers differentially influence the upgrade/downgrade decision while also modeling the effect of transactional, membership and socio-demographic variables. The posited hypotheses are tested with a multinomial logit model with selection using multi-source (archival and survey) consumer-level data related to renewable service memberships in a not-for-profit context. Results suggest that modification decisions are driven by relational payoffs from ongoing experiences such that upgrade decisions evidence a 'motivator' effect of consumer trust (quadratic), while downgrade decisions indicate a negative influence of consumer trust conditional on perceived knowledge. Managerially, the study indicates that, while membership modification and renewal are disparate decisions with remarkably divergent mechanisms, to examine and analyze them as independent decisions is to risk misjudgments about their determinants and waste resources in investments that are unlikely to yield desired return. [ABSTRACT FROM AUTHOR]

In two predictive-learning experiments, we investigated the role of the informational value of contexts for the formation of context-specific extinction learning. The contexts were each composed of two elements from two dimensions, A and B. In Phase 1 of each experiment, participants received acquisition training with a target cue Z in context A1B1 (the numbers assign particular values on the context dimensions). In Phase 2, participants were trained with conditional discriminations between two other cues, X and Y, for which only one of the two context dimensions was relevant. In a third phase, participants received extinction trials with cue Z in context A2B2. During a final test phase, we observed that a partial change of the extinction context disrupted extinction performance when the extinction context was changed on the dimension that had been trained as being relevant for the conditional discrimination. However, when the extinction context was changed on the irrelevant context dimension, extinction performance was not affected. Our results are consistent with the idea that relevant contexts receive more attention than do irrelevant contexts, leading to stronger context-specific processing of information learned in the former than in the latter type of contexts. [ABSTRACT FROM AUTHOR]

In resurgence, an extinguished instrumental behavior (R1) recovers when a behavior that has replaced it (R2) is also extinguished. The phenomenon may be relevant to understanding relapse that can occur after the termination of 'contingency management' treatments, in which an unwanted behavior (e.g., substance abuse) is reduced by reinforcing an alternative behavior. When reinforcement is discontinued, the unwanted behavior might resurge. However, unlike most resurgence experiments, contingency management treatments also introduce a negative contingency, in which reinforcers are not delivered unless the client has abstained from the unwanted behavior. In two experiments with rats, we therefore examined the effects of adding a negative 'abstinence' contingency to the resurgence design. During response elimination, R2 was not reinforced unless R1 had not been emitted for a minimum period of time (45, 90, or 135 s). In both experiments, adding such a contingency to simple R1 extinction reduced, but did not eliminate, resurgence. In Experiment 2, we found the same effect in a yoked group that could earn reinforcers for R2 at the same points in time as the negative-contingency group, but without the requirement to abstain from R1. Thus, the negative contingency per se did not contribute to the reduction in resurgence. These results suggest that the contingency reduced resurgence by making reinforcers more difficult to earn and more widely spaced in time. This could have allowed the animal to learn that R1 was extinguished in the 'context' of infrequent reinforcement-a context more like that of resurgence testing. The results are thus consistent with a contextual (renewal) account of resurgence. The method might provide a better model of relapse after termination of a contingency management treatment. [ABSTRACT FROM AUTHOR]

Two experiments with human participants were used to investigate recovery of an extinguished learned response after a context change using ABC designs. In an ABC design, the context changes over the three successive stages of acquisition (context A), extinction (context B), and test (context C). In both experiments, we found reduced recovery in groups that had extinction in multiple contexts, and that the extinction contexts acquired inhibitory strength. These results confirm those of previous investigations, that multiple-context extinction can produce less response recovery than single-context extinction, and they also provide new evidence for the involvement of contextual inhibitory processes in extinction in humans. The foregoing results are broadly in line with a protection-from-extinction account of response recovery. Yet, despite the fact that we detected contextual inhibition, predictions based on protection-from-extinction were not fully reliable for the single- and multiple-context group differences that we observed in (1) rates of extinction and (2) the strength of context inhibition. Thus, although evidence was obtained for a protection-from-extinction account of response recovery, this account can not explain all of the data. [ABSTRACT FROM AUTHOR]

The source of renewal of instrumental responding in rats was investigated. In Experiment 1, two responses (R1 and R2) were reinforced with one outcome (O1) in contexts A and B (i.e., R1→O1, R2→O1), and then R2 was extinguished in A and R1 was extinguished in B. At test, the rate of R1 was higher than that of R2 in context A, and the reverse was the case in context B: Renewed responding was independent of the Pavlovian context→O1 associations. In Experiment 2, all rats received R1→O1 and R2→O2 trials in A and then were placed in B, where they were sated on O2 and either did (Group Extinction) or did not (Group No Extinction) receive concurrent extinction of R1 and R2. At test, we found more responding in A than in B for Group Extinction, but not for Group No Extinction, and the renewed responding in A was as sensitive to the current value of the outcome as responding that had not been subject to extinction (i.e., the rate was higher for R1 than for R2). That is, the renewed responding was goal-directed. These results identify the removal of contextual inhibion of either the response or the response→outcome associaon as potenal bases for renewal, and the response→outcome associaon as the source of renewed responding. [ABSTRACT FROM AUTHOR]

In two predictive-learning experiments, we investigated the role of the informational value of contexts for the formation of context-dependent behavior. During Phase 1 of each experiment, participants received either a conditional discrimination in which contexts were relevant (Group Relevant) or a simple discrimination in which contexts were irrelevant (Group Irrelevant). Each experiment also included an ABA renewal procedure. Participants received Z+ in context A during Phase 1, extinction of Z in context B during Phase 2, and were tested with Z in context A during a test phase. In each experiment, extinction of Z proceeded faster and was followed by stronger response recovery in Group Relevant than in Group Irrelevant. In Experiment 2, which included recording of eye-gaze behavior, dwell times on contexts were longer in Group Relevant than in Group Irrelevant. Our results support the idea that relevant contexts receive more attention, leading to stronger context specificity of learning. [ABSTRACT FROM AUTHOR]

Four conditioned suppression experiments with rats, using an ABC renewal design, investigated the effects of compounding the target conditioned excitor with additional, nontarget conditioned excitors during extinction. Experiment 1 showed stronger extinction, as evidenced by less renewal, when the target excitor was extinguished in compound with a second excitor, relative to when it was extinguished with associatively neutral stimuli. Critically, this deepened extinction effect was attenuated (i.e., more renewal occurred) when a third excitor was added during extinction training. This novel demonstration contradicts the predictions of associative learning models based on total error reduction, but it is explicable in terms of a counteraction effect within the framework of the extended comparator hypothesis. The attenuated deepened extinction effect was replicated in Experiments 2a and 3, which also showed that pretraining consisting of weakening the association between the two additional excitors (Experiments 2a and 2b) or weakening the association between one of the additional excitors and the unconditioned stimulus (Experiment 3) attenuated the counteraction effect, thereby resulting in a decrease in responding to the target excitor. These results suggest that more than simple total error reduction determines responding after extinction. [ABSTRACT FROM AUTHOR]

Behavioral conditioning of immune responses is one of the most impressive examples for the bidirectional communication among the nervous and immune systems. We established a model of behaviorally conditioned immunosuppression employing a conditioned taste aversion (CTA) paradigm in the rat pairing a novel taste (saccharin) as a conditioned stimulus (CS) with the immunosuppressive drug cyclosporine A (CsA) as an unconditioned stimulus (US). By re-presenting the CS during evocation, rats avoid drinking the saccharin. Concomitantly animals display an immunosuppression reflected by an ex vivo reduction in splenic T cell proliferation as well as diminished interleukin-2 and interferon-γ production and cytokine mRNA expression, mimicking the actual effect of the US (CsA). Due to the fact that the kinetics of this behaviorally conditioned immunosuppression are completely unknown, extinction of the conditioned response on the behavioral level (CTA) as well as in the immune response needs to be elucidated together with the neural processes mediating the extinction process. [ABSTRACT FROM AUTHOR]

The model for a wide class of any territorially distributed standby systems consisting of unreliable repairable elements is described. It represents special type of closed queuing system in which two maintenance operations - replacements and repairs of failed elements are carried out. The possible applications of the model are discussed. [ABSTRACT FROM AUTHOR]