Search

I report on the first application of a novel, generalized Bayesian reconstruction (BR) method for spectral functions to the characterization of QCD constituents. These spectral functions find applications in off-shell kinetics of the quark-gluon plasma and in calculations of transport coefficients. The new BR method is applied to Euclidean propagator data, obtained in Landau gauge on lattices with Nf = 2 + 1 + 1 dynamical flavors by the “twisted mass at finite temperature” (tmfT) collaboration. The deployed reconstruction method is designed for spectral functions that can exhibit positivity violation (opposed to that of hadronic bound states). The transversal and longitudinal gluon spectral functions show a robust structure composed of quasiparticle peak and a negative trough. Characteristic differences between the hadronic and the plasma phase and between the two channels become visible. We obtain the temperature dependence of the transversal and longitudinal gluon masses. [ABSTRACT FROM AUTHOR]

Successful utilization of SCT modalities often requires utilization of both red cell and platelet transfusions. In this retrospective evaluation of clinical factors affecting transplant engraftment and transfusion utilization at a single transplant center in 505 patients from 2005 through 2009, we found that graft type, donor type and the conditioning regimen intensity significantly affected both the neutrophil engraftment time (P<0.001) and the platelet engraftment time (P<0.001). SCT patients required an average of 6.2 red cell units, and 7.9 platelet transfusions in the first 100 days with a wide s.d. Among auto-SCT patients, 5% required neither RBC nor platelet transfusions. Some reduced-intensity transplants were also associated with no transfusion need, and in allogeneic transplants, conditioning regimen intensity was positively correlated with platelet transfusion events as assessed by multivariate analysis. Other patient characteristics such as gender, graft type, donor type, underlying disease and use of TBI were all independently associated with transfusion needs in SCT patients. Further studies are required to understand the means to minimize transfusions and potential related complications in SCT patients. [ABSTRACT FROM AUTHOR]

Komokiaceans are testate agglutinated protists, extremely diverse and abundant in the deep sea. About 40 species are described and share the same main morphological feature: a test consisting of narrow branching tubules forming a complex system. In some species, the interstices between the tubules are filled by sediment, creating a mudball structure. Because of their unusual and sometimes featureless appearance, komokiaceans were frequently ignored or overlooked until they formal description in 1977. The most recent taxonomy places the Komokiacea within the Foraminifera based on general morphological features. To examine their taxonomic position at the molecular level, we analysed the SSU rDNA sequences of two species, Normanina conferta and Septuma ocotillo, obtained either with specific foraminiferal or universal eukaryotic primers. Many different sequences resulted from this investigation but none of them could clearly be attributed to komokiaceans. Although our study failed to confirm univocally that Komokiacea are foraminiferans, it revealed a huge eukaryotic richness associated with these organisms, comparable with the richness in the overall surrounding sediment. These observations suggest strongly that komokiaceans, and probably many other large testate protists, provide a habitat structure for a large spectrum of eukaryotes, significantly contributing to maintaining the biodiversity of micro- and meiofaunal communities in the deep sea. [ABSTRACT FROM AUTHOR]

Recent molecular studies of symbiotic dinoflagellates (genus Symbiodinium) from a wide array of invertebrate hosts have revealed exceptional fine-scale symbiont diversity whose distribution among hosts, regions and environments exhibits significant biogeographic, ecological and evolutionary patterns. Here, similar molecular approaches using the internal transcribed spacer-2 (ITS-2) region were applied to investigate cryptic diversity in Symbiodinium inhabiting soritid foraminifera. Approximately 1,000 soritid specimens were collected and examined during a 12-month period over a 40 m depth gradient from a single reef in Guam, Micronesia. Out of 61 ITS-2 types distinguished, 46 were novel. Most types found are specific for soritid hosts, except for three types (C1, C15 and C19) that are common in metazoan hosts. The distribution of these symbionts was compared with the phylotype of their foraminiferal hosts, based on soritid small subunit ribosomal DNA sequences, and three new phylotypes of soritid hosts were identified based on these sequences. Phylogenetic analyses of 645 host-symbiont pairings revealed that most Symbiodinium types associated specifically with a particular foraminiferal host genus or species, and that the genetic diversity of these symbiont types was positively correlated with the genetic diversity found within each of the three host genera. Compared to previous molecular studies of Symbiodinium from other locations worldwide, the diversity reported here is exceptional and suggests that Micronesian coral reefs are home to a remarkably large Symbiodinium assemblage. [ABSTRACT FROM AUTHOR]

Mitochondrial genomes have recently become widely used in animal phylogeny, mainly to infer the relationships between vertebrates and other bilaterians. However, only 11 of 723 complete mitochondrial genomes available in the public databases are of early metazoans, including cnidarians (Anthozoa, mainly Scleractinia) and sponges. Although some cnidarians (Medusozoa) are known to possess atypical linear mitochondrial DNA, the anthozoan mitochondrial genome is circular and its organization is similar to that of other metazoans. Because the phylogenetic relationships among Anthozoa as well as their relation to other early metazoans still need to be clarified, we tested whether sequencing the complete mitochondrial genome of Savalia savaglia, an anthozoan belonging to the order Zoantharia (=Zoanthidea), could be useful to infer such relationships. Compared to other anthozoans, S. savaglia’s genome is unusually long (20,766 bp) due to the presence of several noncoding intergenic regions (3691 bp). The genome contains all 13 protein coding genes commonly found in metazoans, but like other Anthozoa it lacks most of the tRNAs. Phylogenetic analyses of S. savaglia mitochondrial sequences show Zoantharia branching closely to other Hexacorallia, either as a sister group to Actiniaria or as a sister group to Actiniaria and Scleractinia. The close relationships suggested between Zoantharia and Actiniaria are reinforced by strong similarities in their gene order and the presence of similar introns in the COI and ND5 genes. Our study suggests that mitochondrial genomes can be a source of potentially valuable information on the phylogeny of Hexacorallia and may provide new insights into the evolution of early metazoans. [ABSTRACT FROM AUTHOR]

Zoantharia (or Zoanthidea) is the third largest order of Hexacorallia, characterised by two rows of tentacles, one siphonoglyph and a colonial way of life. Current systematics of Zoantharia is based exclusively on morphology and follows the traditional division of the group into the two suborders Brachycnemina and Macrocnemina, each comprising several poorly defined genera and species. To resolve the phylogenetic relationships among Zoantharia, we have analysed the sequences of mitochondrial 16S and 12S rRNA genes obtained from 24 specimens, representing two suborders and eight genera. In view of our data, Brachycnemina appears as a monophyletic group diverging within the paraphyletic Macrocnemina. The macrocnemic genus Epizoanthus branches as the sister group to all other Zoantharia that are sampled. All examined genera are monophyletic, except Parazoanthus, which comprises several independently branching clades and individual sequences. Among Parazoanthus, some groups of species can be defined by particular insertion/deletion patterns in the DNA sequences. All these clades show specificity to a particular type of substrate such as sponges or hydrozoans. Substrate specificity is also observed in zoantharians living on gorgonians or anthipatharians, as in the genus Savalia ( Gerardia). If confirmed by further studies, the substrate specificity could be used as reliable character for taxonomic identification of some Macrocnemina. [ABSTRACT FROM AUTHOR]

Large discoidal soritid foraminiferans (Soritinae) are abundant in coral reef ecosystems. As with the many cnidarian invertebrates that inhabit these systems, they also depend on symbiotic dinoflagellates (Symbiodinium) for their growth and survival. Several particularSymbiodiniumsub-genera or clades inhabit these soritids. One of these groups, referred to as clade C, dominates corals and their relatives throughout the tropical Indo-Pacific. In contrast, the distributions ofSymbiodiniumspp. from clades A, B, and C are more evenly apportioned across Caribbean invertebrate communities. To explore the possibility that a similar biogeographic break exists in the symbionts harbored by soritids, we surveyed theSymbiodiniumspp. from the soritid genusSorites, collected from the Pacific and Caribbean coasts of Panama as well as from Florida. Characterization ofSymbiodiniumobtained from foraminiferal and cnidarian samples was conducted using restriction fragment length polymorphism and phylogenetic analyses of the nuclear internal transcribed spacer region 2 (ITS 2) and a portion of the large subunit ribosomal DNA sequences. A distinctive biogeographic break between the kinds of symbionts found inSoritesfrom the East Pacific and Caribbean was clearly evident. Differences between cnidarian and foraminferan symbioses in each ocean may be explained by the subjection of Caribbean communities to severer environmental conditions during the early Quarternary. CaribbeanSoritesspp. harbored symbionts described from clade F (specifically sub-clade Fr4) and clade H (formally referred to as Fr1), whileSoritesspp. from the eastern Pacific were dominated by a singleSymbiodiniumhaplotype in clade C. An ITS 2 phylogeny determined that most clade C “types” recovered from Indo-Pacific soritids form a monophyletic sub-lineage with other clade C symbionts typically found in Pacific corals from the genusPorites. The existence of multipleSymbiodiniumlineages at various taxonomic levels associated specifically with soritids indicates that symbioses with these hosts are important in drivingSymbiodiniumspp. evolution. [ABSTRACT FROM AUTHOR]

Presents information on a study which reported the morphology of the ciliate Maristentor dinoferus. Methodology; Occurrence, ecology and behavior; Discussion of the results.

It has been found empirically that the Virasoro center and three-point functions of quantum Liouville field theory with the potential exp(2bϕ(x)) and the external primary fields exp(αϕ(x)) are invariant with respect to the duality transformations ℏα→q−α, where q=b−1+b. The steps leading to this result (via the Virasoro algebra and three-point functions) are reviewed in the path-integral formalism. The duality occurs because the quantum relationship between the α and the conformal weights Δα is two-to-one. As a result, the quantum Liouville potential can actually contain two exponentials (with related parameters). In the two-exponential theory, the duality appears naturally, and an important previously conjectured extrapolation can be proved. [ABSTRACT FROM AUTHOR]

Objective: To identify the site(s) in tumor necrosis factor (TNF α), interleukin-6 (IL-6), and macrophage inflammatory protein-1 α (MIP-1 α) biosynthesis that is blocked by SB202190, a selective inhibitor of p38-mitogen activated protein kinase (p38). ¶ Materials: Human blood monocytes isolated by centrifugal elutriation. ¶ Methods: Monocytes were stimulated with lipopolysaccharide in the presence of 0, 0.3, 1 and 3 μM SB202190. Induced TNF α, IL-6, and MIP-1 α protein and mRNA were measured by ELISA and quantitative RT-PCR, respectively. The half-lives of cytokine mRNA levels were determined following treatment of cells with actinomycin D or SB202190. ¶ Results: SB202190 suppressed >60% of lipopolysaccharide-induced TNF α, IL-6, and MIP-1 α protein and mRNA expression. Suppressed mRNA levels could be attributed to a >2 to 7-fold reduction in cytokine mRNA half-lives. In contrast, SB202190 did not destabilize mRNAs encoding interferon-induced gene 15 protein and glyceraldehyde-3-phosphate dehydrogenase. ¶ Conclusions: Specific mRNA destabilization represents an important and novel site of action for the cytokine suppressive effects of p38 inhibitors. [ABSTRACT FROM AUTHOR]

Two-dimensional and three-dimensional Green-Naghdi (GN) models equipped with a numerical wave-absorbing beach have been developed to simulate nonlinear, regular, and irregular wave propagation. The numerical beach is introduced near the downstream boundary to absorb outgoing waves. An appropriate amount of numerical damping and an appropriate length of numerical beach are investigated using numerical experiments. The results show that the GN models with a numerical beach work very well in simulating wave propagation in water in a small computational domain. [ABSTRACT FROM AUTHOR]

Homogeneous 3 α-hydroxysteroid dehydrogenase (3 α-HSD; EC 1.1.1.50) of rat liver cytosol is a monomeric (MR 34000) NAD(P) dependent oxidoreductase which displays 9-, 11- & 15-hydroxyprostaglandin dehydrogenase activity. The enzyme is potently inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs), suggesting that 3 α-HSD may be a target enzyme for NSAIDs. A monospecific, polyclonal anti-sera raised against the purified enzyme was used to screen a λgt11 expression library and oligonucleotide probes complementary to the 5′ and 3′ ends of immunopositive clones were used to isolate a 2.1 kb full-length cDNA. Digestion of the full-length cDNA with Eco RI generated two fragments of 1.1 and 1.0 kb in length. Both fragments were subcloned into pGEM3 and partially sequenced. The 1.1. kb fragment contains the C-terminus of 3 α-HSD which was confirmed by an in-frame stop codon and comparison of the predicted amino acid sequence to peptide sequence obtained from two endo lys-C peptides of 3 α-HSD. The 1.0 kb fragment is 5′ to the 1.1 kb fragment and is sufficient in length to contain the remainder of the entire open reading frame for 3 α-HSD. Dideoxysequencing reveals significant sequence homology with bovine lung prostaglandin PGF synthase. These findings support the role 3 α-HSD in inflammation and suggest that hydroxysteroid dehydrogenases, hydroxyprostaglandin dehydrogenases and prostaglandin F synthase may be members of a common gene family. [ABSTRACT FROM AUTHOR]

Copyright of Rheologica Acta is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rheologica Acta is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rheologica Acta is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Kolloid Zeitschrift is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Kolloid Zeitschrift is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Kolloid Zeitschrift is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Kolloid Zeitschrift is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Kolloid Zeitschrift is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The asymptotic safety scenario in gravity is accessed within the systematic vertex expansion scheme for functional renormalisation group flows put forward in Christiansen et al. (Phys Lett B 728:114, 2014), Christiansen et al. (Phy Rev D 93:044036, 2016), and implemented in Christiansen et al. (Phys Rev D 92:121501, 2015) for propagators and three-point functions. In the present work this expansion scheme is extended to the dynamical graviton four-point function. For the first time, this provides us with a closed flow equation for the graviton propagator: all vertices and propagators involved are computed from their own flows. In terms of a covariant operator expansion the current approximation gives access to Λ, R, R2 as well as Rμν2 and higher derivative operators. We find a UV fixed point with three attractive and two repulsive directions, thus confirming previous studies on the relevance of the first three operators. In the infrared we find trajectories that correspond to classical general relativity and further show non-classical behaviour in some fluctuation couplings. We also find signatures for the apparent convergence of the systematic vertex expansion. This opens a promising path towards establishing asymptotically safe gravity in terms of apparent convergence. [ABSTRACT FROM AUTHOR]

Presents photographs of Maristentor dinoferus, a giant heterotrich ciliate with zooxanthellae, from coral reefs in Guam, Mariana Islands.

Discusses the discovery of the marine green alga Caulerpa taxifolia on the Californian coast. Comparison of the Californian strain to one found in the Mediterranean Sea; Effect of the bacteria on native bacteria; Possibility that the bacteria originated in Australia.

The dawn of animals remains one of the most mysterious milestones in the evolution of life. The fossil lipids 24-isopropylcholestane and 26-methylstigmastane are considered diagnostic for demosponges-arguably the oldest group of living animals. The widespread occurrence and high relative abundance of these biomarkers in Ediacaran sediments from 635-541 million years (Myr) ago have been viewed as evidence for the rise of animals to ecological importance approximately 100 Myr before their rapid Cambrian radiation. Here we show that the biosynthesis of 24-isopropylcholestane and 26-methylstigmastane precursors is common among early-branching unicellular Rhizaria-heterotrophic protists that play an important role in trophic cycling and carbon export in the modern ocean. Negating these hydrocarbons as sponge biomarkers, our study places the oldest evidence for animals closer to the Cambrian Explosion. Cambrian silica hexactine spicules that are approximately 535 Myr old now represent the oldest diagnostic sponge remains, whereas approximately 558-Myr-old Dickinsonia and Kimberella (Ediacara biota) provide the most reliable evidence for the emergence of animals. The proliferation of predatory protists may have been responsible for much of the ecological changes during the late Neoproterozoic, including the rise of algae, the establishment of complex trophic relationships and the oxygenation of shallow-water habitats required for the subsequent ascent of macroscopic animals.