Search

Introduction / objectives: Stressful events like earthquakes might worsen the symptoms of fibromyalgia, although the influence of medications on these consequences is yet uncertain. The objective of this study was to examine the influence of an earthquake on the symptoms of fibromyalgia and evaluate the impacts of medications used to treat fibromyalgia on the clinical picture. Method: Ninety-five fibromyalgia patients were enrolled in a comparative study and divided into two groups: medication and non-medication. Three subcategories of medication groups were established: selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and gabapentinoid drugs (GDs). Before and after the earthquake, clinical evaluations were conducted using the Fibromyalgia Impact Questionnaire (FIQ), Hospital Anxiety and Depression Scale (HADS), and Jenkins Sleep Rating Scale (JSS). Statistical analyses were conducted to compare the scores before and after the earthquake and evaluate the differences between the groups. Results: Statistically significant increases were observed in FIQ, HADS-anxiety, HADS-depression, and JSS scores in the medication and non-medication groups before and after the earthquake comparisons (p < 0.05). Non-medication group reported significantly higher post-earthquake changes in FIQ, HADS-anxiety, HADS-depression, and JSS compared to the medication group (p < 0.05). While HADS-anxiety, HADS-depression, and JSS changes after the earthquake differed according to the drug subgroups (p < 0.05), no statistically significant difference was observed in FIQ values (p > 0.05). The highest scores were detected in the GD subgroup. Conclusions: This study highlights the substantial impact of earthquakes on fibromyalgia patients. Medication use may assist in reducing the detrimental effects of stresses like earthquakes on fibromyalgia symptomatology. Future research with larger sample sizes and more extended follow-up periods is needed to explain these findings and optimize treatment regimens for fibromyalgia patients experiencing significant stressors. [ABSTRACT FROM AUTHOR]

This article examines the complex interactions between inflammatory rheumatic diseases (IRDs) and men's health. It delves into the effects of IRDs on reproductive health, erectile dysfunction, prostate involvement, male osteoporosis, body composition, physical activity, and coping mechanisms. The findings show that the prevalence of sexual dysfunction varies among different diseases, underscoring the necessity for comprehensive counseling. The link between IRDs and prostate health, with a substantial rise in benign prostatic hyperplasia among IRD patients, demonstrates the condition's importance. In contrast to popular belief, osteoporosis mostly affects women; the current study highlights the growing identification of male osteoporosis, particularly in the setting of IRDs. Male RA patients had a significant loss in bone mineral density, highlighting the importance of increasing awareness and tailored therapy to address osteoporosis in men. IRDs affect body composition, with male RA patients showing imbalances characterized by decreased lean body mass and increased fat mass. Given the dynamic nature of these conditions, coping with IRDs necessitates thorough and individualized diversified approaches. The complex link between IRDs and men's health demands continuing research, including longitudinal studies and tailored therapies. The essay promotes a patient-centered approach, recognizing the unique obstacles that males with IRDs confront. [ABSTRACT FROM AUTHOR]

Kayseri, a densely urbanized province in Türkiye, grapples with pressing challenges of air pollution and limited green spaces, accentuating the need for strategic urban planning. This study, utilizing Landsat 8 and Landsat 9 satellite imagery, investigates the evolution of land surface temperatures (LST) and urban heat island (UHI) effects in key districts—Kocasinan, Melikgazi, Talas, and Hacılar—between 2013 and 2022. This research has been complemented with an analysis of the Normalized Difference Vegetation Index (NDVI) and the Normalized Difference Built-Up Index (NDBI), exploring correlations among the LST, UHI, NDVI, and NDBI changes. The findings indicate that a significant portion (65% and 88%) of the study area remained unchanged with respect to the NDVI and NDBI differences. This research's findings reveal that a substantial portion (65% and 88%) of the study area exhibited consistency in the NDVI and NDBI. Noteworthy increases in the NDVI were observed in 20% of the region, while only 4% exhibited higher NDBI. Strikingly, the UHI displayed strong negative correlations with the NDVI and robust positive correlations with the NDBI. The LST changes demonstrated a reduced temperature range, from 21 to 51 °C in 2013, to 18 to 40 °C in 2022. Localized environmental factors, notably at the National Garden site, showcased the most significant temperature variations. Notably, the UHI exhibited strong negative correlations with the NDVI and strong positive correlations with the NDBI. The study's results emphasize the interplay among the NDBI, LST, and UHI and an inverse relationship with the NDVI and NDBI, LST, and UHI. These findings hold implications for urban planning and policymaking, particularly in the context of resilient and sustainable land use planning and the UHI mitigation. This research underscores the intricate interplay among the NDBI, LST, and UHI, highlighting an inverse relationship with the NDVI. These findings hold crucial implications for resilient and sustainable urban planning, particularly in mitigating the UHI effects. Despite limited vacant spaces in Kayseri, geospatial techniques for identifying potential green spaces can facilitate swift UHI mitigation measures. Acknowledging Kayseri's complex dynamics, future research should delve into the UHI responses to urban morphology and design, extending this methodology to analyze the UHI effects in other Turkish cities. This research contributes to a broader understanding of UHI dynamics and sustainable urban planning practices, offering valuable insights for policymakers, urban planners, and researchers alike. [ABSTRACT FROM AUTHOR]

Chronic skin wounds represent a prominent etiological factor in the occurrence of non-traumatic foot amputations on a global scale and pose a substantial threat to the patient's well-being and mortality in the absence of effective treatment strategies. There exists a subset of patients that exhibit an insufficient response to different treatment options, comprising antibiotics, dressings, gauze bandages, debridement, rehabilitation, collagen patch, and vacuum-assisted closure. In this patient group, distinct treatment strategies emerge before surgery and amputation. Ozone therapy is one of them. Ozone exhibits a wide variety of effects such as antimicrobial, anti-inflammatory, antioxidant, and trophic. Its trophic effect is mediated by disinfection, stimulation of granulation tissue, acceleration of the angiogenesis process, and detoxification mechanisms. In this article, we presented the beneficial effect of ozone therapy in a case of chronic skin ulcer associated with livedoid vasculopathy. In this context, we aimed to discuss the role of ozone therapy in the management of chronic skin ulcers. Finally, we focused on ozone therapy as a promising method in inflammatory rheumatic diseases. [ABSTRACT FROM AUTHOR]

Mining activities degrade the landscape and ecosystems by introducing new land uses that alter soil characteristics. Mapping of this degradation is critical, particularly in the context of environmental protection, including climate change research. Even though mining provides significant industrial and economic benefits to society, it also decreases soil organic carbon (SOC) stocks and increases atmospheric carbon levels. This study aims to develop a practical method for determining the changes in SOC in the Altintepe Gold Mine, Ordu, Turkey, due to land cover changes caused by the mining process. 2013 and 2021 Landsat 8 images and CORINE data were used to map the land cover of the study area. NDVI analyses were conducted to detect land cover and SOC stocks, while the NDWI method was used to identify the water surfaces. SOC stock changes on the changed lands were calculated compared to the Turkey Soil Organic Carbon Stock Project database. The results showed that 109.85 ha of forest and 5.30 ha of agricultural land, corresponding to 4450.82 tons of SOC loss, were destroyed in the research area. Since the alterations in SOC levels are commonly determined by verifying remote sensing based analysis results with the site surveys, it becomes quite challenging to conduct such research in areas like Altintepe due to site access restrictions or data unavailability. From this point, this study presents a practical and alternative approach that avoids the necessity of fieldwork and provides a quick SOC change estimation based on the comparison of available data. The results are expected to provide a comprehensive and holistic perspective for the future operations and management of the mine sites and the surrounding environments. [ABSTRACT FROM AUTHOR]

The study presents a GIS- and RS-based diagnostic model to determine the changes in the existing vegetation in the Urla, Çeşme, and Karaburun peninsulas, Turkey, between 2002 and 2017 after the installation of 239 wind power plants (WPP). The vegetation changes in 7 CORINE land cover classes within the 0–1 km (facility zone) and 1–2 km (control zone) buffer zones were detected in relation with the slope and aspect groups using NDVI analysis. The highest amount of negative change in broad-leaved forests, coniferous forests, and land principally occupied by agriculture, with significant areas of natural vegetation, was detected in the 3–5% slope group, while pasture lands, sclerophyllous vegetation and transitional woodland-shrubs showed the highest degradation in 1–2% slope areas. Negative changes in complex cultivation patterns were found to be on the flat surfaces. Except for the pasture lands and sclerophyllous vegetation classes, the highest degradations were observed on north-facing aspects. In all land cover classes, the most degraded areas were found to be within the facility zone. The results and the proposed model are expected to facilitate planning and decision-making processes for locations with similar landscape characteristics. [ABSTRACT FROM AUTHOR]

The aim of this study is to monitor the change of the existing vegetation in the area after the construction of wind power plants (WPPs) by using remote sensing (RS) and geographic information systems (GIS) technologies. The effects of WPPs on green areas have not been fully explored. The aim of this study is to expand on current knowledge and create a diagnostic model that shows the relationship between the turbines and the surrounding vegetation. All inventory data obtained within the scope of this study were compiled in GIS, and their relations in the field, the establishment dates, and numbers of WPPs were revealed. In this study, NDVI method was preferred. As a result, some negative changes were found in terms of slope and aspect according to CORINE (broadleaf forest degradation (BLF) and agricultural lands with natural vegetation degradation (NVA)) classes. While this study is a pioneer for studies in which WPP-related deterioration is made in terms of slope and aspect, it reveals the importance of GIS and RS. At the same time, using the Python programming language in common in GIS studies shows that making calculations with bulk data makes it easier to work in relatively large areas, especially for landscape planning studies. [ABSTRACT FROM AUTHOR]

Agriculture is the largest consumer of freshwater and plays a critical role in addressing global water scarcity. While numerous studies have focused on the water footprint (WF) of various agricultural products, little attention has been paid to changing cropping patterns and their impact on WF. Here, we investigate the impact of conversion from hazelnut fields to kiwi orchards on green, blue, and gray WF between 2010 and 2021 in Ordu, Turkey. Our results show a total increase of 803,901 tons WF for all green, blue, and gray WF. Compared to the previous situation, changing the agricultural product and growing kiwifruit on previously established hazelnut fields increases green WF by 372,106 tons and blue WF by 334,167 tons. Thus, the change of cultivation pattern could significantly contribute to the water scarcity in the area, and at the same time, the increase in WF. Although kiwi cultivation might be advantageous economically, this economic benefit might be an ecological disadvantage as kiwi production is highly dependent on limited blue water resources. Therefore, it is suggested to further promote the rain-fed product, the hazelnut. [ABSTRACT FROM AUTHOR]

Within the scope of the study, the change occurring in the vegetation cover was examined in different temporal and spatial scales for in the example of Kırka boron mining site. Two different satellite images, namely Landsat and Sentinel, were utilized while the competence of these two satellite images were analyzed. Unsupervised classification and vegetation indexes have been used from remote sensing techniques. It was observed that the mining area boundary could not be determined using vegetation indexes, whereas unsupervised classification techniques showed that the miningral site occupies 1144.5 ha area. NDVI and NDRe analyses were conducted to determine the vegetation change outside the mining area. It has been determined that the analyses performed with the NDVI (normalized difference vegetation index) and NDRe (normalized difference red edge index) indexes show different results on water surfaces, while they show similar results in rest of the areas. In NDVI analysis, it has been determined that the two satellite images gave similar results in NDVI analyses, while having higher spatial resolution, sentinel satellite images were able to capture more details. [ABSTRACT FROM AUTHOR]

Purpose: Cerebral vasospasm is the common cause of poor outcome after aneurysmal subarachnoid hemorrhage (aSAH). Although many agents are experimentally and clinicaly used to protect or recover from vasospasm, an effective neurotherapeutic drug is still missing. Erythropoietin (EPO) is recently a promising candidate. The aim of this study is to investigate the dose-dependent effects of recombinant human EPO (rhEPO) on arterial wall in a rat femoral artery vasospasm model. Methods: Thirty two animals were divided into four groups: vasospasm without any treatment (group A), vasospasm +250 IU/kg rhEPO group (group B), vasospasm +500 IU/kg rhEPO group (group C), and control group (group D). Rat femoral artery vasospasm model was used. For groups B and C, 7 days of 250 IU/kg and 500 IU/kg intraperitoneal rhEPO in 0.3 ml saline were administered respectively; and for groups A and D, 0.3 ml saline were administered intraperitoneally without any treatment. After 7 days, histological and morphometric analyses were carried out. Results: Vasospasm alone group demonstrated the highest vessel wall thicknesses, comparing to other groups ( p < 0.001). While for groups B and C, vessel wall thickness values were significantly higher than the control group ( p < 0.001), between these two groups, there was no significant difference achieved ( p > 0.05). Conclusion: In our study, there was no significant difference between the two rhEPO treatment groups, but rhEPO treatment was shown to be histologically and morphometrically effective in vasospasm. However, if dosage of EPO treatment is augmented, successful results may be achieved. [ABSTRACT FROM AUTHOR]