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Since nail psoriasis restricts the patient's daily activities, therapeutic intervention based on reliable and reproducible evaluation is critical. The Nail Psoriasis Severity Index (NAPSI) is a validated scoring tool, but its usefulness is limited by interobserver variability. This study aimed to develop a reliable and accurate NAPSI scoring tool using deep learning. The tool "NAPSI calculator" includes two parts: nail detection from images and NAPSI scoring. NAPSI was annotated by nine nail experts who are board-certified dermatologists with sufficient experience in a specialized clinic for nail diseases. In the final test set, the "NAPSI calculator" correctly located 137/138 nails and scored NAPSI with higher accuracy than the compared six non-board-certified residents: 83.9% vs 65.7%; P = 0.008 and four board-certified non-nail expert dermatologists: 83.9% vs 73.0%; P = 0.005. The "NAPSI calculator" can be readily used in a clinical situation, contributing to raising the medical practice level for nail psoriasis. [ABSTRACT FROM AUTHOR]

Inexpensive and safe energy-storage batteries with high energy densities are in high demand (e.g., for electric vehicles and grid-level renewable energy storage). This study focused on using NaFeCl4, comprising ubiquitous elements, as an electrode material for all-solid-state sodium-ion batteries. Monoclinic NaFeCl4, expected to be the most resource-attractive Fe redox material, is also thermodynamically stable. The Fe2+/3+ redox reaction of the monoclinic NaFeCl4 electrode has a higher potential (3.45 V vs. Na/Na+) than conventional oxide electrodes (e.g., Fe2O3 with 1.5 V vs. Na/Na+) because of the noble properties of chlorine. Additionally, NaFeCl4 exhibits unusually high deformability (99% of the relative density of the pellet) upon uniaxial pressing (382 MPa) at 298 K. NaFeCl4 operates at 333 K in an electrode system containing no electrolyte, thereby realizing next-generation all-solid-state batteries with high safety. A high energy density per positive electrode of 281 Wh kg−1 was achieved using only a simple powder press. [ABSTRACT FROM AUTHOR]

Non-heat-treated Al–Mg-based die casting alloys have been developed for the structural parts of automobiles. In previous studies, alloy compositions with at least 1.0%Si have been proposed to reduce the hot tearing susceptibility (HTS). On the other hand, the increase in the Si content reduces the ductility. For some automotive body structures, Al–Mg alloy die castings with Si content exceeding 1.0% should not have the required ductility. This study aims to develop an Al–Mg alloy with both high ductility and low HTS by investigating the following three characteristics of an Al–4.5Mg–1.0Mn alloy with 0.2%Si added: (1) additional elements to reduce the HTS, (2) the associated mechanical properties (requirements for the automotive company: 0.2% proof stress ≥ 140 MPa and fracture elongation ≥ 15%), and (3) the mechanism of decreasing the HTS. It was revealed that the co-addition of 0.025%Sr, 0.08%Ti, and 0.016%B reduced the HTS when the hydrogen content of the melt was 0.5–1.0 mL/100 g Al. Furthermore, the 0.2% proof stress and fracture elongation of a lower link arm produced via HPDC with the above composition were found to achieve the requirements. It was also indicated that the mechanism of decrease in the HTS by the Sr addition should result from the decrease in the thermal tensile load due to the formation of hydrogen porosity at a lower solid fraction than that without Sr. It is suggested that when 0.025%Sr, 0.08%Ti, and 0.016%B are added to the Al–4.5Mg–1.0Mn–0.2Si alloy, non-heat-treated automotive structural parts with both high ductility and low HTS will be obtained by high-pressure die casting. [ABSTRACT FROM AUTHOR]