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An incisional hernia may occur through the incision area following a surgical operation, through the trocar opening and even through drainage exit points. Various synthetic surgical meshes have recently been used for the surgical repair of incisional hernias. In this study, we analysed the burst strength forces of heavyweight mesh and lightweight mesh in an incisional animal model. Following experimental formation of incisional hernias in 32 Wistar albino rats, they were divided into four groups. Polypropylene suture was used for closure of the abdominal incision in Group 1. In Groups 2, 3 and 4, polyester, polypropylene + polyglactin and polypropylene meshes, respectively, were fixed on the surface of the fascia after closing the defects in the rats. Polypropylene and polyester meshes are classified as heavy mesh. Light mesh is composed of a non-absorbable part (polypropylene) and an absorbable part (polyglactin), which will disappear 80 days after implantation. The rats were sacrificed at the end of the experiment. The pullout force of the fascia and meshes were recorded by use of a digital tension meter. The mean pullout forces for Groups 1, 2, 3 and 4 were found to be 123.4 ± 13.3, 292.33 ± 17.4, 281.66 ± 16.3 and 310.60 ± 26.1 N, respectively. At the end of the experiment, the polypropylene (25 g/cm2) present in the lightweight mesh was found to lose only a small percentage of the burst strength compared to the polypropylene (85 g/cm2) present in the heavyweight mesh. [ABSTRACT FROM AUTHOR]

Objective:This study was designed to evaluate the effects of probiotics on the severity of experimental acute pancreatitis.Design:Experimental study.Setting:Experiments were done in a laboratory at Haydarpasa Numune Teaching and Research Hospital.Subjects:A total of 50 Wistar rats were randomly divided into five groups.Interventions:Group 1 was control group. Group 2 received an intraperitoneal injection of a 20% solution in 0.15 mol/l NaCL. Group 3 was injected NaCL and fed with probiotics. Acute pancreatitis was induced in rats by intrperitoneal injection of L-Arginine in groups 4 and 5. The rats in group 5 were treated with probiotics. The pancreas was removed for histologic examination. Evaluation of the pathologic changes was done by a new combined histopathologic grading scale.Results:The mean scores of fibrosis, acinar cell loss, oedema, parenchymal necrosis, mononuclear cells infiltration, polymorphonuclear leucocytes infiltration, ductal damage and atypical reactive regeneration in group 5 were significantly lower than group 4.Conclusions:We demonstrated that enteral feedings with added probiotics can reduce the severity of acute pancreatitis.Sponsorship:None.European Journal of Clinical Nutrition (2006) 60, 464–468. doi:10.1038/sj.ejcn.1602338; published online 7 December 2005 [ABSTRACT FROM AUTHOR]