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Research shows elevated gender variance among autistic people and more autistic traits among gender diverse people, each of which is related to mental health concerns. Little work has explored broad features of these presentations in a non-clinical sample. College students (n = 174) ages 18–22 years completed questionnaires assessing the broader autism phenotype (BAP), autistic features, nonconformity to gender norms, and internalizing symptoms. Those with more BAP features or autistic communication reported more nonconformity to gender norms. Higher levels of internalizing symptoms were related to more gender nonconformity, BAP, and autistic features. Gender nonconformity marginally moderated the effect of BAP on depression but not anxiety. The BAP, autistic features, and gender nonconformity are important in understanding mental well-being. [ABSTRACT FROM AUTHOR]

Emotion dysregulation is common among autistic people, yet few measures have received psychometric evaluation in this population. We examined the factor structure, reliability, and validity of a commonly-used measure of emotion dysregulation, the Difficulties with Emotion Regulation Scale (DERS), in a sample of 156 autistic adolescents and adults. Data were drawn from the NIH National Database for Autism Research (NDAR) and an author's existing dataset. Results demonstrated that the factor structure generally conformed to the original 6-factor model, with modifications. Reliability analyses revealed good-to-excellent internal consistencies. Validity analyses indicated that the DERS was positively associated with measures of anxiety, depression, and alexithymia. Our findings provide preliminary evidence for the utility of the DERS in a small autistic sample, with minor modifications. [ABSTRACT FROM AUTHOR]

Parents of youth with neurodevelopmental disorders experience unique stressors in family functioning when compared to parents of neurotypical youth. A paucity of research, however, has examined differences in parenting experiences across families of youth with varying neurodevelopmental disorder presentations. This paper focuses on two common and frequently co-occurring conditions: autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD). In this study, we compared parenting stress, parenting efficacy, and the household context across a sample of 90 mothers of adolescents ages 11–16 years with (1) autism, (2) ADHD, or (3) autism and clinically-elevated ADHD symptoms (Autism + ADHD). Our findings demonstrated differences in all three domains of family functioning across these diagnostic groups. Mothers of adolescents in the Autism + ADHD group endorsed greater stress than mothers of adolescents in the Autism alone group. Parenting efficacy and the household context were poorest (i.e., low efficacy and high chaos) among mothers of adolescents with ADHD and significantly greater than in the Autism alone group. Given our results, we highlight the importance of accounting for co-occurring symptomatology in these populations in research and clinical practice. This will help to accurately capture unique needs of the family system and make appropriate treatment recommendations that leverage families' strengths and are sensitive to family stressors. Highlights: Group differences in parenting and household factors were identified between mothers of adolescents with autism, ADHD, or autism and clinically-elevated ADHD symptoms (Autism + ADHD). Parenting stress was highest in the combined Autism + ADHD group and significantly greater than in the Autism alone group. Parenting efficacy and household order were lowest in the ADHD group and significantly different than the Autism alone group. [ABSTRACT FROM AUTHOR]

Both anxiety and autism spectrum disorder (ASD) are associated with atypical physiological activity. Few studies have systematically assessed the resting physiological activity in ASD with co-occurring anxiety disorders. We tested 75 participants divided in four groups: youth with ASD, with (ASD + Anxiety = 22, 6F, 12.29 ± 2.83 years old) and without co-occurring anxiety (ASD Alone = 15, 6F, 11.59 ± 2.85 years old) and compared their physiological profile with that of matched typically developing controls (TDC) with (Anxiety Alone = 16, 6F, 11.24 ± 3.36 years old) and without co-occurring anxiety disorders (TDC = 22, 8F, 11.88 ± 2.88 years old). Results indicated reduced sympathetic and parasympathetic activity at rest in ASD as compared to TDC youth. ASD + Anxiety and Anxiety Alone groups showed different sympathetic, but similar parasympathetic activity. These findings suggest that autonomic profile-based approaches may advance research, diagnosis, and treatment of ASD and anxiety. [ABSTRACT FROM AUTHOR]

Raising a child with autism spectrum disorder (ASD) poses unique challenges that may impact parents’ mental health and parenting experiences. The current study analyzed self-report data from 77 parents of youth with ASD. A serial multiple mediation model revealed that parenting stress (SIPA) and parental mental health (BAI and BDI-II) appears to be impacted by challenging adolescent behaviors (SSIS-PBs) and, in turn, affect parental involvement (PRQ), controlling for social skills (SSIS-SSs). Further, the study explored the malleability of parents’ mental health over the course of a social skills intervention, and provides modest evidence that parent depressive symptoms decline across intervention. This study illustrates the importance of considering the entire family system in research on youth with ASD. [ABSTRACT FROM AUTHOR]

Depression is a common concern among people with autism spectrum disorder (ASD) and is often associated with social skills and relationship challenges. The present data, from a randomized controlled trial, examined the effect of PEERS ® on self-reported depressive symptoms via the Children's Depression Inventory (CDI) among 49 adolescents with ASD. Findings revealed that many CDI subscale scores declined (p's < 0.05) and were related to direct social contact on the Quality of Socialization Questionnaire at posttest (p's < 0.05). Exploratory analyses uncovered that suicidality was less evident following PEERS ®. Findings support the notion that social functioning and depression may be intimately intertwined in ASD; therefore, bolstering social skills in ASD may positively influence other domains of functioning, including mental health. [ABSTRACT FROM AUTHOR]