Search

A bimetallic Pd-Pt catalyst (0.5 and 0.9% w/w of Pd and Pt, respectively) supported on activated carbon has been prepared and tested for hydrodechlorination of dichloromethane (DCM). Different reduction temperatures were used during the catalyst synthesis, and the catalyst reduced at 250 °C was tested under varying reaction conditions, which included H/DCM molar ratio, inlet DCM concentration, reaction temperature and space-time, always at 1 atm pressure. Formation of bimetallic particles was evidenced by TEM. Complete dechlorination was achieved at 250 °C, 2.5 kg h mol space-time and H/DCM = 50. Graphical Abstract: [ABSTRACT FROM AUTHOR]

The aim of this work was to assess the variability in the use of health-care resources, based on the number of visits to rheumatology departments by rheumatoid arthritis patients, in Spain, and its association with patient, physician and center characteristics. The sample consisted of patient records of men and women (aged 16 or older), with a clinical diagnosis of RA, who met the American Rheumatism Association 1987 revised criteria and who had been treated in a rheumatology department at a Spanish hospital with at least one visit to a rheumatologist during the two years preceding the date of the study. To analyze which variables were independently associated with the number of consultations, those with a statistically significant result in the bivariate analysis, or which were clinically relevant or deemed confounders, were used in the construction of a linear regression model. The records of 1188 RA patients were studied. The linear regression model explained the 26.67 % of the variability in the number of visits. The number of csDMARDs prescribed, the administration of biological therapy, corticoid prescription, the presence of nursing consultation, mean time to first visit in the department and attended population showed a positive significant association, while the presence of telephone consultation, distance from the hospital to the patient´s residence (≥20 km) and drug monitoring by rheumatology department + primary care physician or by other specialists were negatively associated with the number of consultations. We observed a high variability in the number of visits, which remains partially unexplained even after taking into account individual, physician and center characteristics. [ABSTRACT FROM AUTHOR]