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2 results on '"Mark Grose"'

1. Oncolytic immunotherapy for the treatment of non-muscle invasive bladder cancer using intravesical coxsackievirus A21

Author

M. Denyer, Hugh Mostafid, Kevin J. Harrington, Attya Iqbal, Darren R. Shafren, Guy Simpson, Sarbjinder S Sandhu, Nicola E. Annels, Alan Melcher, Mehreen Arif, Hardev Pandha, David Mansfield, Gough G. Au, and Mark Grose

Subjects
Pharmacology, Cancer Research, Bladder cancer, business.industry, medicine.medical_treatment, Bladder cancer cell, Immunology, Coxsackievirus A21, Immunotherapy, medicine.disease, Bioinformatics, Oncolytic virus, Oncology, Poster Presentation, Cancer research, medicine, Molecular Medicine, Immunology and Allergy, Non muscle invasive, business
Abstract

Meeting abstracts As a clinical setting in which local live biological therapy is already well established, nonmuscle invasive bladder cancer (NMIBC) presents intriguing opportunities for oncolytic virotherapy. Coxsackievirus A21 (CVA21) is a novel intercellular adhesion molecule-1 (ICAM-1)

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2. Phase I/II storm study: Intravenous delivery of a novel oncolytic immunotherapy agent, Coxsackievirus A21, in advanced cancer patients

Author

Hardev Pandha, Alan Melcher, Kevin J. Harrington, Darren R. Shafren, Christy Ralph, and Mark Grose

Subjects
Pharmacology, Cancer Research, biology, business.industry, medicine.medical_treatment, Melanoma, Immunology, Cell, Coxsackievirus A21, RNA virus, Common cold, Immunotherapy, biology.organism_classification, Bioinformatics, medicine.disease, Oncolytic virus, medicine.anatomical_structure, Oncology, Prostate, Poster Presentation, medicine, Cancer research, Molecular Medicine, Immunology and Allergy, business
Abstract

Meeting abstracts Coxsackievirus A21 (CVA21) is a naturally occurring “common cold” intercellular adhesion molecule-1 (ICAM-1)-targeted RNA virus. Surface ICAM-1 is up-regulated on a number of cancers including melanoma, non-small cell lung, bladder and prostate cancers. CAVATAK is a novel bio

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