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When the envelope of the conducting strips for the input transducer of magnetostatic surface wave (MSSW) device is designed according to the wavelet-function envelope, the impulse-response function of the input transducer for MSSW device is equal to the wavelet function, so that single-scale wavelet-transform processor of MSSW type is fabricated. First, according to the envelope function of the wavelet, the length function of the conducting strips is defined, then, the lengths of the conducting strips can be calculated from the length function of the conducting strips, finally, the input transducer can be designed according to the lengths and widths for the conducting strips. The compensation method of the insertion loss for single-scale wavelet transform processor of MSSW type is also given in the paper. When the output end of single-scale wavelet transform processor of MSSW type is connected to the amplifier, its insertion loss can be compensated. [ABSTRACT FROM AUTHOR]

Hypernatremic myopathy was rarely reported in the literature and its clinical features have never been well-described. We present a 22-year-old man who had adipsic hypernatremia manifested with progressive proximal muscle weakness and remarkably high creatine kinase level that has never been reported in the cases of hypernatremic myopathy. His initial presentations were similar to that of polymyositis without the evidence of central nervous system dysfunction and hypopituitarism. The serum level of sodium at the beginning of myopathy is the lowest known in the literature. All the clinical presentations in this patient resulted from a hypothalamic mixed germ cell tumor with sub-acute intra-tumoral hemorrhage. [ABSTRACT FROM AUTHOR]

Methamphetamine (Meth) is one of the most frequently abused drugs worldwide. Recent studies have indicated that antibodies with high affinity for Meth reduce its pharmacological effects. The purpose of this study was to develop a technique for virus-based passive immunization against Meth effects. We generated a recombinant adeno-associated virus serotype-8 vector (AAV-MethAb) carrying the gene for a Meth-specific monoclonal antibody (MethAb). Infection of 293 cells with AAV-MethAb resulted in the expression and secretion of antibodies which bind to Meth. The viral vector was then examined in adult ICR mice. Systemic administration of AAV-MethAb resulted in long-term expression of MethAb in the serum for up to 29 weeks. Serum collected from the animals receiving AAV-MethAb retained a high specificity for (+)-Meth. Animals were challenged with Meth five weeks after viral injection. Meth levels in the brain and serum were reduced while Meth-induced locomotor activity was significantly attenuated. In conclusion, AAV-MethAb administration effectively depletes Meth from brain and serum while reducing the behavioral response to Meth, and thus is a potential therapeutic approach for Meth abuse. [ABSTRACT FROM AUTHOR]