1. Rationale and design of the DP-TRANSFERS project: diabetes prevention-transferring findings from European research to society in Catalonia
- Author
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Gemma Flores-Mateo, J.J. Cabré, Santiago Mestre, Bernardo Costa, Jaana Lindström, Francisco Barrio, Claustre Sole, Antoni Boquet, Xavier Cos, Conxa Castell, Marta Canela, and Daniel Ferrer-Vidal
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Gerontology ,medicine.medical_specialty ,Biomedical Research ,030209 endocrinology & metabolism ,Translational research ,Health Promotion ,Disease ,General Biochemistry, Genetics and Molecular Biology ,Translational Research, Biomedical ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Intervention (counseling) ,Outcome Assessment, Health Care ,Study protocol ,Protocol ,medicine ,Humans ,030212 general & internal medicine ,Prediabetes ,Diabetes prevention ,Life Style ,Aged ,Medicine(all) ,Public health ,Geography ,business.industry ,Biochemistry, Genetics and Molecular Biology(all) ,Impaired glucose tolerance ,General Medicine ,Middle Aged ,medicine.disease ,Impaired fasting glucose ,Metropolitan area ,Europe ,Diabetes Mellitus, Type 2 ,Research Design ,Scale (social sciences) ,business - Abstract
Background Compelling evidence has been accumulated to support the effectiveness of intensive lifestyle intervention in delaying progression to Type 2 diabetes even in people identified as being at high risk determined by the Finnish diabetes risk score. The DE-PLAN-CAT project (diabetes in Europe-prevention using lifestyle, physical activity and nutritional intervention–Catalonia) evidenced that intensive lifestyle intervention was feasible and cost-effective on a short scale in real-life primary care settings, at least over 4 years. However, transferring such lifestyle interventions to society remains the major challenge of research in the field of diabetes prevention. Methods/design The derived DP-TRANSFERS (diabetes prevention-transferring findings from European research to society) is a large scale national programme aimed at translating a tailored lifestyle intervention to the maximum of primary care centres where feasible through a core proposal agreed with all the partners. The method is built upon a 3-step (screening, intervention and follow-up) real-life, community-wide structure on the basis of a dual intensity lifestyle intervention (basic and continuity modules) and supported by a 4-channel transfer strategy (institutional relationships, facilitators’ workshops, collaborative groupware and programme WEB page). Participation will initially cover nine health departments (7 million inhabitants) through nine coordinating centres located in metropolitan (3.2 million), semi-urban (2.9 million) and rural (0.9 million) areas from which it is expected accessing 25 % of all primary care settings, equivalent to 90 associated centres (1.6–1.8 million people) with an estimate of 0.32 million participants aged 45–75 years at high risk of future development of diabetes. To ascertain sustainability, effect, satisfaction and quality of the translation programme statistical analyses will be performed from both the entire population (facilitators and participants) and a stratified representative sample obtained by collecting data from at least 920 participants. Discussion The DP-TRANSFERS will use a strategy of approach to society consistent with the impact of the disease and the fast accessibility provided by primary care settings in Catalonia. Both the widespread effect of the lifestyle intervention and the translational process itself could be assessed.
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