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The increasing interest in filter pruning of convolutional neural networks stems from its inherent ability to effectively compress and accelerate these networks. Currently, filter pruning is mainly divided into two schools: norm-based and relation-based. These methods aim to selectively remove the least important filters according to predefined rules. However, the limitations of these methods lie in the inadequate consideration of filter diversity and the impact of batch normalization (BN) layers on the input of the next layer, which may lead to performance degradation. To address the above limitations of norm-based and similarity-based methods, this study conducts empirical analyses to reveal their drawbacks and subsequently introduces a groundbreaking complex hybrid weighted pruning method. By evaluating the correlations and norms between individual filters, as well as the parameters of the BN layer, our method effectively identifies and prunes the most redundant filters in a robust manner, thereby avoiding significant decreases in network performance. We conducted comprehensive and direct pruning experiments on different depths of ResNet using publicly available image classification datasets, ImageNet and CIFAR-10. The results demonstrate the significant efficacy of our approach. In particular, when applied to the ResNet-50 on the ImageNet dataset, achieves a significant reduction of 53.5% in floating-point operations, with a performance loss of only 0.6%. [ABSTRACT FROM AUTHOR]

The evolution mechanism behind low cycle fatigue crack propagation behavior subject to overload was investigated by experimental and numerical methods. The retardation effect after the overload application was investigated by using compact tension (CT) specimens. An analysis model was established to consider accumulative plastic damage for CT specimen under single tensile overload. An elastic-plastic numerical model is established, and the stress-strain field near the crack tip is quantified by different numerical parameters. The crack opening displacement was got to reflect the influence of overload on plasticity-induced crack closure, and the evolution mechanism and accumulative plastic damage were investigated by exploring the residual compressive stress near the crack tip. The results show that the residual compressive stress produced by the tensile overload has great influence on the retardation effect, and the large plastic deformation near the crack front region after an overload witnesses a more significant crack closure phenomenon. The magnitude of residual compressive stress near crack tip increases with the increasing overload ratio, that sharpens the retardation effect after single tensile overload. [ABSTRACT FROM AUTHOR]

The recognition of fish species holds significant importance in aquaculture and marine biology. However, it is a challenging problem due to the high similarity among intra-genus species. Existing recognition methods primarily seek prominent features of the species. However, we believe that the diverse levels of similarity between a species and other species can also function as implicit characteristics for that specific species. Based on this perspective, we propose a dual-branch fusion network for fine-grained fish species recognition utilizing inter-species similarity. This approach consists of a backbone network and two branches for coarse- and fine-grained recognition. In the coarse-grained branch, we designed a guidance matrix and species similarity labels to facilitate the generation of species similarity information. In the fine-grained branch, features from the backbone network are fused with similarity information to achieve precise recognition. Finally, fine-tuning the neural network through loss functions. We conduct experimental validation on three publicly available fish datasets, yielding excellent accuracy outcomes. Code is available at https://github.com/xingxing317/fish_classification. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate the changes in the liver volume and function after direct intrahepatic portocaval shunt (DIPS) in patients with Budd-Chiari syndrome (BCS) with diffuse hepatic vein (HV) occlusion. Methods: The clinical data of 29 patients with BCS who underwent DIPS for intractable ascites caused by diffuse hepatic vein occlusion in the Affiliated Hospital of Xuzhou Medical University were analysed retrospectively; the patients included 8 males and 21 females, with an average age of 33.3 ± 6.3 years. The patients underwent abdominal CT scanning and liver function examinations before DIPS, and 1 week, 3 months, 6 months and 12 months after DIPS. The changes of the liver volume and liver function before and after DIPS were compared. Results: All 29 patients underwent DIPS successfully. 28 patients survived during the follow-up of 12–33 months, with a median follow-up of 16 months. The patients' liver function were significantly improved at 3, 6 and 12 months after the operation compared to before the operation (P < 0.05). The liver volumes measured before the operation and 1 week, 3 months, 6 months and 12 months after the operation were 2124.586 ± 420.889 cm3, 1926.263 ± 372.268 cm3, 1480.592 ± 183.061 cm3, 1461.904 ± 153.027 cm3 and 1469.286 ± 148.549 cm3, respectively. Compared with the preoperative liver volume, the liver volume had decreased significantly at 1 week, 3 months, 6 months and 12 months after the operation (P < 0.05). However, there was no significant difference in the liver volumes at 6 and 12 months after the operation (P = 0.35). Conclusions: Direct intrahepatic portocaval shunt has achieved satisfactory clinical results in the treatment of BCS with diffuse hepatic vein occlusion. The congestive hepatomegaly was gradually reduced after the operation. The liver volume (which was defined as the clinical efficacy in this study) remained stable after 6 months. [ABSTRACT FROM AUTHOR]

Abstract   Aims Glaucoma is a common neurodegenerative disease that affects retinal ganglion cells (RGCs) and their axons. Little is known of the synaptic degeneration involved in the pathophysiology of glaucoma. Here we used an experimental ocular hypertension model in rats to investigate this issue. Methods Elevated intraocular pressure (IOP) was induced by laser coagulation of the episcleral and limbal veins. RGCs were retrogradely labeled with Fluoro-Gold (FG). The c-fos protein was used as a neuronal connectivity marker. Expression of c-fos in the retinas was investigated by immunohistochemistry at 5 days and 2 weeks after the induction of ocular hypertension. Both surviving RGCs as revealed by retrograde FG-labeled and c-fos-labeled RGCs were counted. Results The c-fos protein was mainly expressed in the nuclei and nucleoli of cells in the ganglion cell layer and inner nuclear layer in the normal retina. We also confirmed that c-fos was also expressed in the nuclei and nucleoli of RGCs retrogradely labeled with FG. There was no significant RGC loss at 5 days but about 13% RGC loss at 2 weeks after the induction of ocular hypertension. The number of RGCs expressing c-fos was significantly lower in the experimental animals at both 5 days and 2 weeks than normal. Conclusion Our study suggests that there is synaptic disconnection for RGCs after ocular hypertension and it may precede the cell death in the early stage. It may provide insight into novel therapeutic strategies to slow the progress of glaucoma. [ABSTRACT FROM AUTHOR]

Purpose: The aim of this study was to determine the anatomical variations of the superior transverse scapular ligament (STSL) for better understanding the possible predisposing factors for suprascapular nerve entrapment. Methods: The study was using fifty 10% formalin solution-fixed human cadaveric shoulders. After dissection of the suprascapular region, the length, medial width, lateral width and middle width of the suprascapular opening were measured for each STSL. Results: The STSL displayed six types as: (1) band-shaped in 11 cases; (2) fan-shaped in 27 cases; (3) triangular-shaped in 5 cases; (4) linear type in 2 cases; (5) bifid in 1 case; (6) absent in 1 case. The ossified type of STSL was found in 3 cases. There were statistically significant differences in the length (P = 0.009), medial width (P = 0.001), lateral width (P = 0.029) of the three types of fan-shaped, band-shaped and triangular-shaped. However, there was no statistical difference in the middle width of the suprascapular opening of the three types (P = 0.340). Conclusion: Knowing the morphological features and variations of the STSL is important for better understanding the anatomical conditions, which could be taken into consideration during open suprascapular operations or arthroscopic decompressions. [ABSTRACT FROM AUTHOR]

The article discusses Internet-based software that China's Ministry of Science and Technology developed to measure savings that people can make in energy use and emissions on a daily basis. Called the Counter of Energy Conservation and Emission Reduction, the software is said to reduce the lag in public participation in improving energy-related environmental conditions. The software addresses areas of family life and habits that include water use, cooking, use of paper, use of environmentally-friendly products, home-appliance use, and clothes washing.

Background: To get a better cosmetic effect, and to avoid even a small incision and scar in the anterior neck zone, we adapted gasless endoscopic thyroidectomy via anterior chest approach. Methods: From June 2004 to June 2008, 219 patients with thyroid diseases underwent gasless endoscopic thyroidectomy via anterior chest approach. The clinical and pathologic characteristics of patients, the type of operation, operative time, length of postoperative hospital stay, and postoperative complications were analyzed retrospectively. Results: All 219 operations were successfully performed endoscopically. Only three patients showed temporary paralysis of the recurrent laryngeal nerve (RLN), and all of them recovered within 1-3 months after the surgery. One patient showed permanent paralysis of the RLN, one patient developed a postoperative seroma, and one patient suffered a tracheal injury. There were no injuries to the superior laryngeal nerve or any hypoparathyroidism. No further complications, such as irritating cough, tetany, and emphysema developed after the operation. Because of the anterior chest wall approach, none of the patients had a surgical scar on the neck and all were satisfied with the cosmetic effect. Conclusions: Gasless endoscopic thyroid surgery through anterior chest approach is a feasible and safe method. This technique had better cosmetic results and could constitute a new treatment modality for patients with benign tumors and can also be an effective alternative treatment for the selected patients with thyroid cancer. [ABSTRACT FROM AUTHOR]

The physiological stress suffered by patients with coronary heart disease (CHD) may result in a shift in leukocyte differential toward a decreased percentage of lymphocytes ( L%). The purpose of this study was to determine the prognostic value of a low L% in CHD. One hundred forty patients evaluated in our department between 2007 and 2008 were retrospectively reviewed. Thirty-eight patients had primary percutaneous coronary intervention (PCI), and 102 patients had elective PCI. Various statistical analyses were used to examine the association between a low L% or other clinical characteristics and CHD. Univariate analysis showed that low L% was significantly related to ACS compared with stable CHD or control. White blood cell (WBC) count, C-reactive protein (CRP) and left ventricular systolic dysfunction (LVSD) were also correlated with CHD. Multivariate analysis and logistic regression analysis revealed that L%, CRP, WBC count and LVSD were all independently significant risk factors to have predictive value for CHD and 1 year major adverse cardiac events (MACE). A low L% could be used as an independent predictor for ACS on admission and is associated with MACE during clinical follow-up in CHD patients. [ABSTRACT FROM AUTHOR]

In this study we utilized computational fluid dynamic (CFD) techniques to construct a numerical simulation of nasal cavity airflow pre and post virtual functional endoscopic surgery (FESS). A healthy subject was selected, and CFD techniques were then applied to construct an anatomically and proportionally accurate three-dimensional nasal model based on nasal CT scans. A virtual FESS intervention was performed numerically on the normal nasal model using Fluent software. Navier-Stokes and continuity equations were used to calculate and compare airflow, velocity, distribution and pressure in both the pre and post FESS models. In the post-FESS model, there was an increase in airflow distribution in the maxillary, ethmoid and sphenoid sinuses, and a 13% increase through the area connecting the middle meatus and the surgically opened ethmoid. There was a gradual decrease in nasal resistance in the posterior ethmoid sinus region following FESS. These findings highlight the potential of this technique as a powerful preoperative assessment tool to aid clinical decision-making. [ABSTRACT FROM AUTHOR]

Drug addiction is considered an aberrant form of learning, and drug-associated memories evoked by the presence of associated stimuli (drug context or drug-related cues) contribute to recurrent craving and reinstatement. Epigenetic changes mediated by DNA methyltransferase (DNMT) have been implicated in the reconsolidation of fear memory. Here, we investigated the role of DNMT activity in the reconsolidation of cocaine-associated memories. Rats were trained over 10 days to intravenously self-administer cocaine by nosepokes. Each injection was paired with a light/tone conditioned stimulus (CS). After acquisition of stable self-administration behaviour, rats underwent nosepoke extinction (10 d) followed by cue-induced reactivation and subsequent cue-induced and cocaine-priming + cue-induced reinstatement tests or subsequently tested to assess the strength of the cocaine-associated cue as a conditioned reinforcer to drive cocaine seeking behaviour. Bilateral intra-basolateral amygdala (BLA) infusion of the DNMT inhibitor5-azacytidine (5-AZA, 1 μg per side) immediately following reactivation decreased subsequent reinstatement induced by cues or cocaine priming as well as cue-maintained cocaine-seeking behaviour. In contrast, delayed intra-BLA infusion of 5-AZA 6 h after reactivation or 5-AZA infusion without reactivation had no effect on subsequent cue-induced reinstatement. These findings indicate that memory reconsolidation for a cocaine-paired stimulus depends critically on DNMT activity in the BLA. [ABSTRACT FROM AUTHOR]