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A previously undescribed badnavirus was isolated from Zamia fischeri showing symptoms of chlorosis, necrosis, and ringspot. The virus has bacilliform virions 30 nm in diameter and averaging 120 nm in length. The viral genome is 9227 bp in length and contains three open reading frames characteristic of members of the genus Badnavirus. The largest open reading frame (ORF3) encodes a putative polyprotein, with predicted domains including zinc finger, aspartic protease, reverse transcriptase (RT) and RNase H. The virus is tentatively named "cycad leaf necrosis virus" (CLNV). Within the genus Badnavirus, CLNV was most closely related to sugarcane bacilliform Guadeloupe D virus (FJ439817), sharing 69% identity at the nucleotide level in the RT + RNase H region. This virus is the first badnavirus reported to infect cycads, and it has the largest genome among the currently characterized badnaviruses. [ABSTRACT FROM AUTHOR]

A prototype of a heavy liquid metal free surface target as proposed for the multi-purpose hybrid research reactor for high-tech applications in Mol, Belgium, has been set up and experimentally investigated at the Karlsruhe Liquid Metal Laboratory. A stable operation was demonstrated in a wide range of operating conditions and the surface shape was detected and compared with numerical pre-calculations employing Star-CD. Results show a very good agreement of experiment and numerical predictions which is an essential input for other windowless target designs like the META:LIC target for the European Spallation Source. [ABSTRACT FROM AUTHOR]

Copyright of Manuelle Medizin is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The retention behavior of large polycyclic aromatic hydrocarbons (LPAHs) (≥ 7 rings) on newly developed metalloprotoporphyrin (MProP)-silica stationary phases is examined and the results are compared to previously reported data for retention of the same solutes on commercially available phases. HPLC columns packed with FeProP-silica are shown to exhibit unique shape selectivity for LPAH retention, with the planar LPAHs always retained much longer than corresponding non-planar solutes. Solute planarity, length to breadth ratio (L/B value), and number of carbon atoms within the LPAHs are all demonstrated to contribute to the retention sequence observed. Further, the retention of LPAH solutes on FeProP-silica phases is shown to be more predictable than on other reversed-phase columns, with the elution sequence constant regardless of the mobile phase composition. Due to the extremely high planar selectivity of FeProP-silicas with respect to LPAH retention, it is envisioned that columns packed with these phases could be used in conjunction with existing commercial columns to devise methods for more efficient separation of complex mixtures of LPAHs in environmental and other samples. [ABSTRACT FROM AUTHOR]

A hybrid boundary element method (BEM)/finite element method (FEM) approach is proposed in order to properly consider the anisotropic properties of the cardiac muscle in the magneto- and electrocardiographic forward problem. Within the anisotropic myocardium a bidomain model based FEM formulation is applied. In the surrounding isotropic volume conductor the BEM is adopted. Coupling is enabled by requesting continuity of the electric potential and the normal of the current density across the boundary of the heart. Here, the BEM part is coupled as an equivalent finite element to the finite element stiffness matrix, thus preserving in part its sparse property. First, continuous convergence of the coupling scheme is shown for a spherical model comparing the computed results to an analytic reference solution. Then, the method is extended to the depolarization phase in a fibrous model of a dog ventricle. A precomputed activation sequence obtained using a fine mesh of the heart was downsampled and used to calculate body surface potentials and extracorporal magnetic fields considering the anisotropic bidomain conductivities. Results are compared to those obtained by neglecting in part or totally (oblique or uniform dipole layer model) anisotropic properties. The relatively large errors computed indicate that the cardiac muscle is one of the major torso inhomogeneities. © 2000 Biomedical Engineering Society. PAC00: 8719Nn, 8719Hh, 8719Ff, 8710+e, 8717Nn [ABSTRACT FROM AUTHOR]

Copyright of Electrical Engineering is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archiv für Elektrotechnik is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archiv für Elektrotechnik is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The retention behavior of large polycyclic aromatic hydrocarbons (PAH) in reversed-phase microcolumn liquid chromatography has been found to depend primarily on the inherent planarity of the molecules, the degree of orderliness of the bonded phase, and the concentration of solvent. The planarity recognition capability of cholesteryl 10-undecenoate bonded phase for large PAH is comparable with that of monomeric ODS phases. During solvation, however, the phase characteristics seemed to suggest a fairly rigid structure (an ordered phase), i.e. increased selectivity for non-planar molecules which approaches that of polymeric ODS rather than that of other phases with similarly bulky groups, e.g. naphthylethyl and pyrenylethyl bonded phases. [ABSTRACT FROM AUTHOR]

The author comments on the importance of improving an employee's performance review as a career management strategy. He offers several tips and a different attitude about performance reviews. He mentions the importance of a preparation for turning performance reviews into something positive that will help an employee stand out and gain the edge in performance-based results.

The author reflects on issues related to the occurrence of conflicts within research groups. To avoid conflicts, the author states that everyone in the laboratory should do things in a more orderly manner and understand what the others do. According to the author, scientists should avoid gossiping or making jokes about coworkers because it can lead to less productive working relationships.

The article focuses on the personal and professional benefits of working in a small pharmaceutical startup company. Briefly discussed are the influences behind the corporate culture in such a company setting such as a supervisor's personality and attitudes. It also cites some of the limited resources of startups which may affect its management in gaining investments like access to scientific literature.

Discusses the advantages and disadvantages of being a professor in the analytical chemistry field. Independence in selecting research areas; Scramble of professors to obtain research funding; Involvement in scientific societies and journals; Altruism of teaching.

The article presents information on the determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization. Lactic acid in mammals is mainly composed of the L-form which is produced from pyruvic acid under anaerobic conditions. But its optical isomer, D-lactic acid, also exists in mammals even though the amount is approximately 1.0% relative to L-lactic acid. For the determination of D-lactic acid in blood, serum, or plasma, the reported methods have mostly utilized D-lactic acid dehydrogenase, which transforms D-lactic acid to pyruvic acid.

The article discusses accepted writing styles in technical publications. It informs that the contents of the technical paper must be much more detailed than the description given in a fifteen or twenty minute talk. The giving of a much more detailed description, however, cannot be the reason why we expect papers to be so much more straightforward and dry than the analogous talk. A published paper does not have to be flashy. It does not have to be fine literature. It does not have to be good comedy. It can, however, be human, containing touches reflecting each of us as people in addition to our being scientists.

The article reports that one of the current trends in analytical chemistry is for research to be very focused on certain applications areas. Among these are proteomics or recombinant DNA analysis or characterization of nanostructures. Scientists from many fields have come together to help create these new, very hot, topical areas. Each of the resulting hybrid disciplines of study can be very dynamic. The wide recognition, the large number of publications, and the high levels of funding are all to be found within these hot topical fields. The keen interest attracts experienced scientists from a wide variety of areas and also graduate and post-doctoral students.