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In this work, we have successfully synthesized three kinds of morphological MnO2 (α, δ, γ-MnO2) with mesoporous structures. The performance of catalysts were evaluated by catalytic oxidation of phenol in saline wastewater using ozone as oxidant at room temperature. The catalysts were characterized by XRD, SEM, BET, O2-TPD/TPO, TGA and XPS, respectively. The results demonstrate that γ-MnO2 catalyst is the most active catalyst for phenol removal. It is found that the changes of valence of Mn promote the degradation of phenol, and the existence of lattice oxygen (Olatt) facilitates the circulation of Mn in different valence states. Therefore, Mn4+/Mn3+ and Olatt as active components significantly improved the catalytic activity of γ-MnO2 and have the best stability. [ABSTRACT FROM AUTHOR]

Goldfish is an ornamental fish with diverse phenotypes. However, the limited genomic resources of goldfish hamper our understanding of the genetic basis for its phenotypic diversity. To provide enriched genomic resources and infer possible mechanisms underlying skin pigmentation, we performed a large-scale transcriptomic sequencing on 13 adult goldfish tissues, larvae at one- and three-days post hatch, and skin tissues with four different color pigmentation. A total of 25.52 Gb and 149.80 Gb clean data were obtained using the PacBio and Illumina platforms, respectively. Onto the goldfish reference genome, we mapped 137,674 non-redundant transcripts, of which 5.54% was known isoforms and 78.53% was novel isoforms of the reference genes, and the remaining 21,926 isoforms are novel isoforms of additional new genes. Both skin-specific and color-specific transcriptomic analyses showed that several significantly enriched genes were known to be involved in melanogenesis, tyrosine metabolism, PPAR signaling pathway, folate biosynthesis metabolism and so on. Thirteen differentially expressed genes across different color skins were associated with melanogenesis and pteridine synthesis including mitf, ednrb, mc1r, tyr, mlph and gch1, and xanthophore differentiation such as pax7, slc2a11 and slc2a15. These transcriptomic data revealed pathways involved in goldfish pigmentation and improved the gene annotation of the reference genome. [ABSTRACT FROM AUTHOR]

A series Cu decorated MnO2/γ-Al2O3 catalysts (Cu load, 1%, 3% and 5%) was fabricated by facile co-impregnation method, and investigated for the catalytic oxidative removal Na2S in waste water. Compared with MnO2/γ-Al2O3, the catalytic activity and stability of Cu-MnO2/γ-Al2O3, was enhanced by modifying with Cu element. XRD, SEM, BET, H2-TPR and XPS were carried out to characterize these catalyst. XRD and BET show the Cu successfully decorated on the MnO2/γ-Al2O3, and catalyst's pristine structure are well maintained. SEM shows that the doped Cu species benefits to the uniform dispersion of Mn species, H2-TPR suggests that the reodox capacity of Cu decorated catalysts were improved after doping with Cu, and XPS shows that doped Cu produces higher concentration of Mn4+ and Oads (surface active oxygen species), also expediting the redox cycling between Mn4+/Mn3+ and the promote the Oads production, which resulting in the enhancement of redox properties. Hence, 3%Cu-MnO2/γ-Al2O3 catalyst could achieve 97.5% degradation of Na2S in waste water at room conditions in 2 h, by the help of air, this result is superior to other published work. [ABSTRACT FROM AUTHOR]

Our objective is to analyze and observe the different administration routes of parecoxib sodium pretreatment on the behavioral improvement of rats with neuropathic pain to provide the preclinical data of parecoxib sodium on neuropathic pain treatment. 30 SD rats were randomly divided into five groups, including model group, sham operation group, intrathecal injection group (IT group), intraperitoneal injection group (IP group), and perineural infiltration group (PI group). The rats in model group and three parecoxib sodium pretreatment groups received spinal nerve ligation (SNL). Heat pain test and 50 % paw mechanical withdrawal threshold test (50 % PMWT) were use to assess the responses after parecoxib sodium pretreatment. 50 % PMWT results of right foot in five groups had no statistical difference ( P > 0.05); 50 % PMWT results of left and right feet in three parecoxib sodium pretreatment groups were obviously higher than SNL group at different time points, which was statistically different ( P < 0.05); in comparison with three pretreatment groups, the data of left foot in IT group were obviously higher than PI group and IP group, and the comparison among three groups had significant difference ( P < 0.05). However, the data of right foot had no significant difference among three groups ( P > 0.05). Paw thermal withdrawal latency (PTWL) results of left and right feet in five groups had no significant difference before surgery ( P > 0.05); after the establishment of neuropathic model, PTWL results in five groups were significantly decreased; however, PTWL results of left and right feet at 3 days after surgery in IT group were significantly higher than the two other pretreatment groups ( P < 0.05); PTWL results of left and right feet at 7 and 14 days after surgery had no significant difference. Parecoxib sodium pretreatment can effectively improve the behaviors caused by neuropathic pain, and intrathecal injection is the most effective route of administration. [ABSTRACT FROM AUTHOR]